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Steven L. Highfill, PhD
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Journal Articles

Deep and Durable Remissions of Relapsed Multiple Myeloma on a First-in-Humans Clinical Trial of T Cells Expressing an Anti-B-Cell Maturation Antigen (BCMA) Chimeric Antigen Receptor (CAR) with a Fully-Human Heavy-Chain-Only Antigen Recognition Domain

Lekha Mikkilineni, MD, Elisabet E. Manasanch, MD, Danielle Vanasse, BS, Jennifer N. Brudno, MD, Jennifer Mann, CRNP, Richard Sherry, MD, Stephanie L Goff, MD, James C Yang, MD, Norris Lam, BS, Irina Maric, MD MSci, Maryalice Stetler-Stevenson, MD PhD, Hao-Wei Wang, MD PhD, Constance M. Yuan, MD PhD, David F. Stroncek, MD, Steven L Highfill, PhD, Vicki Fellowes, Micaela Ganadan, BSN, RN, Rashmika Patel, Steven A Rosenberg, MD PhD, James N. Kochenderfer, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 50–51.
https://doi.org/10.1182/blood-2020-138839
Published: 2020
Journal Articles

Cell Density of NK Cells during Ex Vivo Expansion Impacts NK Cell Surface TRAIL Expression

Joseph A. Clara, MD, Robert Reger, MS, Mala Chakraborty, PhD, Steven L Highfill, PhD, Jianjian Jin, PhD, David F. Stroncek, MD, Richard W. Childs, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
https://doi.org/10.1182/blood-2020-141487
Published: 2020
Journal Articles

Abbreviated T-Cell Activation on the Automated Clinimacs Prodigy Device Enhances Bispecific CD19/22 Chimeric Antigen Receptor T-Cell Viability and Fold Expansion, Reducing Total Culture Duration

Sandeep K Srivastava, PhD, Sandhya R. Panch, MD MPH, Jianjian Jin, PhD, Haneen Shalabi, DO, Nirali N. Shah, MD, Steven L Highfill, PhD, David F. Stroncek
Journal: Blood
Blood (2018) 132 (Supplement 1): 4551.
https://doi.org/10.1182/blood-2018-99-116846
Published: 2018
Journal Articles

Very Early Adoptive Transfer of Ex Vivo Generated Multi-Virus Specific T Cells Is a Safe Strategy for Prevention of Viral Infection after Allogeneic T Cell Depleted Stem Cell Transplantation

Pawel Muranski, MD, Sarah I Davies, Sawa Ito, MD, Eleftheria Koklanaris, RN, Jeanine Superata, RN, Quan Yu, Steven L Highfill, PhD, Marianna Sabatino, MD, David F. Stroncek, Minoo Battiwalla, MD, Austin John Barrett
Journal: Blood
Blood (2018) 132 (Supplement 1): 812.
https://doi.org/10.1182/blood-2018-99-119314
Published: 2018
Journal Articles

CD4/CD8 T-Cell Selection Enhances CD22 CAR-T Cell Transduction and in-Vivo CAR-T Expansion: Updated Results on Phase I Anti-CD22 CAR Dose Expansion Cohort

Nirali N Shah, MD, Steven L Highfill, PhD, Haneen Shalabi, DO, Bonnie Yates, RN, Eli Kane, Vicki Fellowes, Cynthia Delbrook, RN, Jiaqiang Ren, MD PhD, Jianjian Jin, David Stroncek, MD, Terry J. Fry, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 809.
https://doi.org/10.1182/blood.V130.Suppl_1.809.809
Published: 2017
Journal Articles

Modulation of CD22 Antigen Density Improves Efficacy of CD22 Chimeric Antigen Receptor (CAR) T Cells Against CD22 lo B-Lineage Leukemia and Lymphoma

Sneha Ramakrishna, MD, Sang M Nguyen, BS, Haiying Qin, MS, Steven L Highfill, PhD, Ira Kraft, John Shern, MD, Zachary Walsh, Dimiter Dimitrov, PhD, Terry J Fry, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3894.
https://doi.org/10.1182/blood.V130.Suppl_1.3894.3894
Published: 2017
Journal Articles

The Post-Thaw Recovery of Cryopreserved Chimeric Antigen Receptor (CAR) T-Cells during Manufacture Is Better Than That of Cryopreserved Peripheral Blood CD3+ Cells

Nasha Elavia, MD MBBS, Andrew McManus, Steven L Highfill, PhD, Jiaqiang Ren, MD PhD, Nirali N Shah, MD, Terry J. Fry, MD, Jennifer Brudno, MD, James N. Kochenderfer, MD, David Stroncek, MD, Sandhya R. Panch, MDMPH
Journal: Blood
Blood (2017) 130 (Supplement 1): 4475.
https://doi.org/10.1182/blood.V130.Suppl_1.4475.4475
Published: 2017
Journal Articles

Early Adoptive Transfer of Ex Vivo Generated Multi-Virus Specific T Cells Is a Safe Strategy to Prevent Viral Reactivation in Recipients of Allogeneic T Cell Depleted Stem Cell Transplant

Pawel Muranski, MD, Greg Whitehill, BS, Debbie Draper, RN, Eleftheria Koklanaris, RN, Jeanine Superata, RN, Quan Yu, MS, Marianna Sabatino, MD, Steven L. Highfill, PhD, Hanh Khuu, MD, Sarah I Davies, Mark Chang, Upneet Chawla, BS, MD, Alexandros Spyridonidis, MD PhD, Gary Fahle, MT,SM, Sawa Ito, MD PhD, David Stroncek, MD, Minoo Battiwalla, MDMS, John Barrett, MD
Journal: Blood
Blood (2016) 128 (22): 979.
https://doi.org/10.1182/blood.V128.22.979.979
Published: 2016
Journal Articles

Bone Marrow Myeloid-Derived Suppressor Cells (MDSC) Inhibit Graft Versus Host Disease (GVHD) Via An Arginase-1 Dependant Mechanism That Is Upregulated by IL-13

Steven L Highfill, PhD, Paulo Rodriguez, PhD, Qing Zhou, PhD, Christine A Goetz, PhD, Rachelle Veenstra, Patricia A Taylor, DVM, Angela Panoskaltsis-Mortari, PhD, Jonathan Serody, MD, David Munn, Jakub Tolar, MD, PhD, Augusto C Ochoa, MD, Bruce R. Blazar, MD
Journal: Blood
Blood (2010) 116 (21): 241.
https://doi.org/10.1182/blood.V116.21.241.241
Published: 2010