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Journal Articles

Hematopoietic Mononuclear Cell Transplant with Minimal Gvhd in up to Completely Mismatched Unrelated Recipients

Suzanne T Ildstad, MD

Blood (2019) 134 (Supplement_1): 3243.

https://doi.org/10.1182/blood-2019-130943

Published: 2019

Journal Articles

Use of a Processed Hematopoietic Stem Cell Product (FCRx) in Unmatched Related and Unrelated Donor — Recipient Pairs Is Associated with High Levels of Donor Chimerism and Donor-Specific Tolerance to Kidney Allografts

Joseph R. Leventhal, MD PhD, John P. Galvin, MDMS,MPH, James Mathew, PhD, Lorenzo Gallon, MD, Kadiyala Ravindra, MD, Mitchell E. Horwitz, MD, Michael Abecassis, MD, MBA, Suzanne T Ildstad, MD

Blood (2018) 132 (Supplement 1): 202.

https://doi.org/10.1182/blood-2018-99-118832

Published: 2018

Journal Articles

CD8 + TCR - Bone Marrow Facilitating Cells Prime Migration and Enhance Homing of Hematopoietic Stem Cells

Yujie Wen, MD PhD, Yiming Huang, MD, Thomas O Miller, BS, Mariusz Z Ratajczak, MD PhD, Suzanne T Ildstad, MD

Blood (2014) 124 (21): 2412.

https://doi.org/10.1182/blood.V124.21.2412.2412

Published: 2014

Journal Articles

Immune Reconstitution in Recipients of Living Donor Kidney/Hematopoietic Stem + Facilitating Cell Transplants

Joseph R. Leventhal, MD PhD, Mary J Elliott, Esma S. Yolcu, PhD, Larry D. Bozulic, PhD, David J Tollerud, MD MPH, James M Mathew, PhD, Iwona M Konieczna, Michael G Ison, MD, Mark Badder, Michael M I Abecassis, MD MBA, Joshua Miller, MD, Suzanne T. Ildstad, MD

Blood (2014) 124 (21): 191.

https://doi.org/10.1182/blood.V124.21.191.191

Published: 2014

Journal Articles

Human Facilitating Cells (FCs): Two Distinct, Complementary, and Synergistic CD56 Subpopulations That Uniquely Define FC Function

Yiming Huang, MD, Mary J Elliott, BS, Thomas O Miller, BS, Janina Ratajczak, MD PhD, Larry D Bozulic, PhD, Yujie Wen, MD PhD, Hong Xu, MD, Mariusz Z Ratajczak, MD PhD, Suzanne T. Ildstad, MD

Blood (2014) 124 (21): 1106.

https://doi.org/10.1182/blood.V124.21.1106.1106

Published: 2014

Journal Articles

Evaluation Of Immunocompentence In Tolerant Chimeric Recipients Of Hematopoietic Stem Cell/Renal Transplants

Joseph Leventhal, MD, PhD, Larry D Bozulic, PhD, Mark D. Badder, MSc, Mary Jane Elliott, M.S., Michael N Issa, M.D., James Mathew, M.D., Iwona Konieczna, Suzanne T. Ildstad, MD

Blood (2013) 122 (21): 4483.

https://doi.org/10.1182/blood.V122.21.4483.4483

Published: 2013

Journal Articles

Update On Phase 2 Clinical Trial To Induce Tolerance In Mismatched Living Donor Renal Transplant Recipients

Joseph Leventhal, MD, PhD, Michael Abecassis, MD, Joshua Miller, MD, Lorenzo Gallon, MD, David J Tollerud, MD, MPH, Suzanne T. Ildstad, MD

Blood (2013) 122 (21): 4622.

https://doi.org/10.1182/blood.V122.21.4622.4622

Published: 2013

Journal Articles

Human CD8 + / TCR − / CD56 dim / - Facilitating Cells Facilitate Homing and Engraftment of Human HSC in Vivo

Yiming Huang, MD, Mary J Elliott, Thomas Miller, Deborah R Corbin, Larry D. Bozulic, PhD, Hong Xu, MD, Yujie Wen, Maryam Jazayeri, PhD, Suzanne T. Ildstad, MD

Blood (2012) 120 (21): 4093.

https://doi.org/10.1182/blood.V120.21.4093.4093

Published: 2012

Journal Articles

Flt3-Ligand Plays a Critical Role in Development and Function of CD8 + /TCR − Facilitating Cells in Bone Marrow,

Yiming Huang, MD, Thomas Miller, Hong Xu, MD, Yujie Wen, M.D., Ph.D., Suzanne T Ildstad, MD

Blood (2011) 118 (21): 4003.

https://doi.org/10.1182/blood.V118.21.4003.4003

Published: 2011

Journal Articles

Durable Chimerism, Absence of Graft-Versus-Host Disease and the Induction of Donor Specific Tolerance in Recipients of HLA Disparate Living Donor Kidney Transplants and Therapeutic Cell Transfer

Joseph Leventhal, Michael Abecassis, M.D., Joshua Miller, M.D., Lorenzo Gallon, M.D., Kadiyala Ravindra, M.D., David J Tollerud, MD, MPH, Bradley J King, Geoffrey Herzig, M.D., Roger Herzig, MD, Suzanne T Ildstad, MD

Blood (2011) 118 (21): 832.

https://doi.org/10.1182/blood.V118.21.832.832

Published: 2011

Journal Articles

The CXCR4 Antagonist AMD 3100 Induces Rapid Mobilization of Facilitating Cells and Hematopoietic Stem Cells in Mice

Hong Xu, MD, Ziqiang Zhu, MD, Yiming Huang, MD, Suzanne T. Ildstad, MD

Blood (2011) 118 (21): 4694.

https://doi.org/10.1182/blood.V118.21.4694.4694

Published: 2011

Journal Articles

A Critical Role for Innate Immunity In Allogeneic Hematopoietic Cell Rejection Via the TLR4/TRIF Pathway

Hong Xu, MD, Jun Yan, MD, PhD, Ziqiang Zhu, MD, Yiming Huang, MD, Yujie Wen, MD, PhD, Larry D Bozulic, PhD, Suzanne T. Ildstad, MD

Blood (2010) 116 (21): 77.

https://doi.org/10.1182/blood.V116.21.77.77

Published: 2010

Journal Articles

Human CD8 + /TCR − /CD56 dim/− facilitating Cells Enhance Engraftment of HSC In NOD/SCID/IL2rγ null Recipients.

Yiming Huang, MD, Mary J Elliott, Deborah M Ramsey, Thomas Miller, Larry D Bozulic, Ashley A Ocker, Bradley J King, Suzanne T. Ildstad, MD

Blood (2010) 116 (21): 3709.

https://doi.org/10.1182/blood.V116.21.3709.3709

Published: 2010

Journal Articles

CD8 + /TCR − Facilitating Cells Induce Generation of Regulatory T cells in Vivo: Chimeric Regulatory T Cells are Antigen-Specific and Enhance Engraftment of Allogeneic HSC in Non-Obese Diabetic (NOD) Mice.

Yiming Huang, M.D., Larry D Bozulic, Ph.D, Thomas Miller, B.S., Hong Xu, M.D., Lala-Rukh Hussain, B.S., Suzanne T. Ildstad, MD

Blood (2008) 112 (11): 2318.

https://doi.org/10.1182/blood.V112.11.2318.2318

Published: 2008

Journal Articles

CD154:CD40 Co-Stimulatory Blockade: A Specific Approach To Prevent Sensitization to Donor Alloantigens.

Hong Xu, MD, Jun Yan, MD, PhD, Suzanne T. Ildstad, MD

Blood (2007) 110 (11): 2246.

https://doi.org/10.1182/blood.V110.11.2246.2246

Published: 2007

Journal Articles

CD154 Blockade Prevents Allosensitization through Inhibiting Both T- and B-Cell Activation and Decreasing Expression of IFN-γ and IL-10 in T-Cells.

Hong Xu, MD, Jun Yan, MD PhD, Yiming Huang, MD, Paula M. Chilton, PhD, Michael K. Tanner, MS, Lala-Rukh Hussain, BS, Suzanne T. Ildstad, MD

Blood (2007) 110 (11): 1346.

https://doi.org/10.1182/blood.V110.11.1346.1346

Published: 2007

Journal Articles

CD8 + /TCR − Graft Facilitating Cells Enhance HSC Engraftment and Survival Via TNF-α Mediated Prevention of Apoptosis.

Suzanne T. Ildstad, MD, Francine Rezzoug, PhD, Yiming Huang, MD, Marcin Wysoczynski, Carrie L. Schanie, Mariusz Z. Ratajczak, MD, Ph.D, Isabelle J. Fugier-Vivier, PhD

Blood (2005) 106 (11): 1352.

https://doi.org/10.1182/blood.V106.11.1352.1352

Published: 2005

Journal Articles

CD154:CD40 Co-Stimulatory Blockade: A Novel Approach To Prevent Sensitization to Donor Alloantigens.

Hong Xu, MD, Jun Yan, MD, PhD, Suzanne T. Ildstad, MD

Blood (2005) 106 (11): 1273.

https://doi.org/10.1182/blood.V106.11.1273.1273

Published: 2005

Journal Articles

In the Absence of Preformed Antibody, Sensitized T Cells Mediate an Increased Barrier to Engraftment.

Hong Xu, MD, Paula M. Chilton, PhD, Yiming Huang, MD, Carrie L. Schanie, Michael K. Tanner, Mariano Dy-Liacco, MD, Lala-Rukh Hussain, Suzanne T. Ildstad, MD

Blood (2005) 106 (11): 191.

https://doi.org/10.1182/blood.V106.11.191.191

Published: 2005

Journal Articles

TNFα Mediated Facilitating Cell Enhancement of Hematopoietic Stem Cell Function in Vivo and In Vitro Involves Bcl-3.

Francine Rezzoug, Ph.D., Yiming Huang, Michael K. Tanner, Marcin Wysoczynski, Carrie L. Shannie, Mariusz Z. Ratajczak, MD.Ph.D., Isabelle J. Fugie-Vivier, Ph.D, Suzanne T. Ildstad, MD.

Blood (2004) 104 (11): 2174.

https://doi.org/10.1182/blood.V104.11.2174.2174

Published: 2004

NARROW

Hematopoietic Mononuclear Cell Transplant with Minimal Gvhd in up to Completely Mismatched Unrelated Recipients

Use of a Processed Hematopoietic Stem Cell Product (FCRx) in Unmatched Related and Unrelated Donor — Recipient Pairs Is Associated with High Levels of Donor Chimerism and Donor-Specific Tolerance to Kidney Allografts

CD8 + TCR - Bone Marrow Facilitating Cells Prime Migration and Enhance Homing of Hematopoietic Stem Cells

Immune Reconstitution in Recipients of Living Donor Kidney/Hematopoietic Stem + Facilitating Cell Transplants

Human Facilitating Cells (FCs): Two Distinct, Complementary, and Synergistic CD56 Subpopulations That Uniquely Define FC Function

Evaluation Of Immunocompentence In Tolerant Chimeric Recipients Of Hematopoietic Stem Cell/Renal Transplants

Update On Phase 2 Clinical Trial To Induce Tolerance In Mismatched Living Donor Renal Transplant Recipients

Human CD8 + / TCR − / CD56 dim / - Facilitating Cells Facilitate Homing and Engraftment of Human HSC in Vivo

Flt3-Ligand Plays a Critical Role in Development and Function of CD8 + /TCR − Facilitating Cells in Bone Marrow,

Durable Chimerism, Absence of Graft-Versus-Host Disease and the Induction of Donor Specific Tolerance in Recipients of HLA Disparate Living Donor Kidney Transplants and Therapeutic Cell Transfer

The CXCR4 Antagonist AMD 3100 Induces Rapid Mobilization of Facilitating Cells and Hematopoietic Stem Cells in Mice

A Critical Role for Innate Immunity In Allogeneic Hematopoietic Cell Rejection Via the TLR4/TRIF Pathway

Human CD8 + /TCR − /CD56 dim/− facilitating Cells Enhance Engraftment of HSC In NOD/SCID/IL2rγ null Recipients.

CD8 + /TCR − Facilitating Cells Induce Generation of Regulatory T cells in Vivo: Chimeric Regulatory T Cells are Antigen-Specific and Enhance Engraftment of Allogeneic HSC in Non-Obese Diabetic (NOD) Mice.

CD154:CD40 Co-Stimulatory Blockade: A Specific Approach To Prevent Sensitization to Donor Alloantigens.

CD154 Blockade Prevents Allosensitization through Inhibiting Both T- and B-Cell Activation and Decreasing Expression of IFN-γ and IL-10 in T-Cells.

CD8 + /TCR − Graft Facilitating Cells Enhance HSC Engraftment and Survival Via TNF-α Mediated Prevention of Apoptosis.

CD154:CD40 Co-Stimulatory Blockade: A Novel Approach To Prevent Sensitization to Donor Alloantigens.

In the Absence of Preformed Antibody, Sensitized T Cells Mediate an Increased Barrier to Engraftment.

TNFα Mediated Facilitating Cell Enhancement of Hematopoietic Stem Cell Function in Vivo and In Vitro Involves Bcl-3.

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American Society of Hematology

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American Society of Hematology

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