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Szymon M. Kielbasa
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Journal Articles

Detection of Occurrent Somatic Hypermutation and Associated Gene Expression Profile in Single B Cells

Julieta Sepulveda-Yanez, Diego Alvarez-Saravia, David Medina, Edwin Quinten, Szymon M. Kiełbasa, Marcelo Navarrete, Cornelis A.M. van Bergen, Hendrik Veelken
Journal: Blood
Blood (2023) 142 (Supplement 1): 4139.
https://doi.org/10.1182/blood-2023-190074
Published: 2023
Journal Articles

B-Cell Receptor Function and Gene Expression Profiling at Single-Cell Level across the Spectrum from Normal to Neoplastic CD5-Positive B-Cell Compartments in Humans

Edwin Quinten, Julieta Sepulveda-Yanez, Ramin Monajemi, Roberta Menafra, Susan L. Kloet, Szymon M. Kiełbasa, Cornelis A.M. van Bergen, Hendrik Veelken
Journal: Blood
Blood (2023) 142 (Supplement 1): 1885.
https://doi.org/10.1182/blood-2023-189097
Published: 2023
Journal Articles

"Snapshotting" Somatic Hypermutation in Single Follicular Lymphoma Cells

Juleta H. Sepulveda-Yanez, Diego Alvarez-Saravia, Edwin Quinten, Roberta Menafra, Susan L. Kloet, Ramin Monajemi, Szymon M. Kielbasa, Marcelo Navarrete Signorile, Cornelis A.M. van Bergen, Hendrik Veelken
Journal: Blood
Blood (2021) 138 (Supplement 1): 1151.
https://doi.org/10.1182/blood-2021-150475
Published: 2021
Journal Articles

High-Throughput BCR Sequencing and Single-Cell Transcriptomics Reveal Distinct Transcriptional Profiles Associated with Subclonal Evolution of Follicular Lymphoma

Cornelis A.M. van Bergen, Marvyn T. Koning, BSc, Edwin Quinten, Agnieszka Mykowiecka, MSc, Julieta Sepulveda, MSc, Ramin Monajemi, PhD, Ruben A.L. De Groen, Joost Vermaat, MD PhD, Susan L. Kloet, PhD, Szymon M. Kielbasa, PhD, Marcelo A. Navarrete, PhD, Pawel Górecki, PhD, Hendrik Veelken, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 298.
https://doi.org/10.1182/blood-2019-130508
Published: 2019
Journal Articles

Primary Cutaneous Follicle Center Lymphomas (PCFCL) Express Heavily Mutated B-Cell Receptors with Acquired N-Glycosylation Motifs and Lack Ongoing Somatic Hypermutation

Marvyn T. Koning, BSc, Edwin Quinten, Willem H. Zoutman, Sander A.J. van der Zeeuw, Szymon M. Kielbasa, PhD, Hailang Mei, PhD, Cornelis A.M. van Bergen, PhD, Patty M. Jansen, MD PhD, Rein Willemze, MD PhD, Christian Schmidt, MD, Maarten Vermeer, MD PhD, Cornelis P. Tensen, PhD, Hendrik Veelken, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1573.
https://doi.org/10.1182/blood-2018-99-115134
Published: 2018
Journal Articles

Whole Transcriptome RNA Sequencing As a Comprehensive Diagnostic Tool for Acute Myeloid Leukemia

Marieke Griffioen, PhD, Wibowo Arindrarto, Daniel M. Borras, PhD, Irene J. Locher, Saskia A.M.E. van Diessen, Rosalie van der Holst, Edith D. van der Meijden, M. Willy Honders, Rick H. de Leeuw, Inge Jedema, PhD, Wilma G.M. Kroes, Jeroen Knijnenburg, PhD, Joost Vermaat, MD PhD, Peter Valk, PhD, Bart Janssen, PhD, Peter de Knijff, PhD, Cornelis A.M. van Bergen, PhD, Erik B. van den Akker, PhD, Peter A.C. 't Hoen, PhD, Szymon M. Kielbasa, PhD, Jeroen F.J. Laros, PhD, Hendrik Veelken, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2762.
https://doi.org/10.1182/blood-2018-99-111115
Published: 2018
Journal Articles

Fusion Transcripts without Corresponding Cytogenetic Abnormalities in Acute Myeloid Leukemia: Implications for AML Pathogenesis

Irene J. Locher, Wibowo Arindrarto, M.Sc., Daniel M. Borràs, M.Sc., M. Willy Honders, ing., Rick H. de Leeuw, ing., Wilma G.M. Kroes, PhD, Peter de Knijff, PhD, Cornelis A.M. van Bergen, PhD, Peter A.C. 't Hoen, PhD, Szymon M. Kielbasa, PhD, Jeroen F.J. Laros, PhD, Marieke Griffioen, PhD, Hendrik Veelken, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2703.
https://doi.org/10.1182/blood.V130.Suppl_1.2703.2703
Published: 2017
Journal Articles

Primary Mediastinal Large B-Cell Lymphoma Exhibits Autonomous BCR Signaling and Responds to the Second Generation BTK Inhibitor Acalabrutinib

Marvyn T. Koning, BSc, Rudolf Übelhart, PhD, Sander A.J. van der Zeeuw, BSc, Philip Kluin, MD PhD, Marieke Griffioen, PhD, Hans G. Drexler, MD PhD, Szymon M. Kielbasa, PhD, Marcelo A. Navarrete, MD PhD, Hassan Jumaa, PhD, Hendrik Veelken, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4171.
https://doi.org/10.1182/blood.V128.22.4171.4171
Published: 2016
Journal Articles

Antigen-Independent, Autonomous B-Cell Receptor Signaling As a Dominant Candidate Oncogenic Mechanism in ABC DLBCL

Marvyn T. Koning, BSc, Rudolf Übelhart, PhD, Arjen H.G. Cleven, PhD, Willem H. Zoutman, BSc, Sander A.J. van der Zeeuw, BSc, Philip Kluin, MD PhD, Marieke Griffioen, PhD, Cornelis P. Tensen, PhD, Maarten H. Vermeer, MD PhD, Rein Willemze, MD PhD, Szymon M. Kielbasa, PhD, Marcelo A. Navarrete, MD PhD, Hassan Jumaa, PhD, Hendrik Veelken, MD PhD
Journal: Blood
Blood (2016) 128 (22): 778.
https://doi.org/10.1182/blood.V128.22.778.778
Published: 2016
Journal Articles

Whole Transcriptome Sequencing (RNAseq) As a Comprehensive, Cost-Efficient Diagnostic Tool for Acute Myeloid Leukemia

Marieke Griffioen, PhD, Wibowo Arindrarto, MSc, Daniel Borràs, MSc, Saskia A.M.E. van Diessen, BSc, Edith D. van der Meijden, M. Willy Honders, Mariam Alloul, PhD, Inge Jedema, PhD, Wilma G.M. Kroes, PhD, Peter J.M. Valk, PhD, Bart Janssen, PhD, Cornelis A.M. van Bergen, PhD, Szymon M. Kiełbasa, PhD, Jeroen F.J. Laros, PhD, Peter A.C. 't Hoen, PhD, Hendrik Veelken, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1701.
https://doi.org/10.1182/blood.V128.22.1701.1701
Published: 2016
Journal Articles

Massive Parallel Sequencing of Full-Length B-Cell Receptor Sequences Reveals HLA-Dependent Shaping of the B-Cell Immune Repertoire

Marvyn T. Koning, Sander A.J. van der Zeeuw, Marcelo Navarrete, MD, Cornelis A.M. van Bergen, Valeri Nteleah, MSc, Marieke Griffioen, PhD, Szymon M. Kiełbasa, PhD, Hendrik Veelken, MDPhD
Journal: Blood
Blood (2014) 124 (21): 4143.
https://doi.org/10.1182/blood.V124.21.4143.4143
Published: 2014