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Journal Articles

Bone Marrow Cell Based Enzyme Replacement Prolongs Survival and Improves Disease Phenotypes In a Mouse Model Of Lethal Hypophosphatasia

Osamu Iijima, PhD, Koichi Miyake, MD, PhD, Aki Nakamura, DDS, Tsutomu Igarashi, MD, PhD, Chizu Kanokoda, Atsushi Watanabe, MD, PhD, Takashi Shimada, MD, PhD

Blood (2013) 122 (21): 2897.

https://doi.org/10.1182/blood.V122.21.2897.2897

Published: 2013

Journal Articles

Rescue of Lethal Hypophosphatasia Mice by Neonatal Ex Vivo Gene Therapy Using Lentivirally Transduced Bone Marrow Cells.

Osamu Iijima, PhD, Koichi Miyake, MD, PhD, Hanako Sugano-Tajima, MD, PhD, Tsutomu Igarashi, MD, PhD, Chizu Kanokoda, Atsushi Watanabe, MD, PhD, Takashi Shimada, MD, PhD

Blood (2012) 120 (21): 3154.

https://doi.org/10.1182/blood.V120.21.3154.3154

Published: 2012

Journal Articles

AAV8 vector expressing IL24 efficiently suppresses tumor growth mediated by specific mechanisms in MLL/AF4 -positive ALL model mice

Hayato Tamai, Koichi Miyake, Hiroki Yamaguchi, Miyuki Takatori, Kazuo Dan, Koiti Inokuchi, Takashi Shimada

Blood (2012) 119 (1): 64–71.

https://doi.org/10.1182/blood-2011-05-354050

Published: 2012

Includes: Supplemental data

Journal Articles

The Clinical Features and Prognostic Impact of DNMT3A Gene Mutation in Japanese Patients with De Novo AML

Takeshi Ryotokuji, MD, Hiroki Yamaguchi, MD, PhD, Ikuko Omori, Tuneaki Hirakawa, MD, PhD, Satoshi Wakita, MD, Tomoaki Kitano, Yoshio Mitamura, Fumiko Kosaka, Takashi Shimada, MD, PhD, Koiti Inokuchi, MD, PhD, Kazuo Dan, MD, PhD

Blood (2011) 118 (21): 2537.

https://doi.org/10.1182/blood.V118.21.2537.2537

Published: 2011

Journal Articles

Gene Mutations in Paired Initial Presentation and Relapse Samples From Acute Myeloid Leukemia Patients,

Satoshi Wakita, MD, Hiroki Yamaguchi, MD, PhD, Yoshio Mitamura, Fumiko Kosaka, Takashi Shimada, MD, PhD, Koiti Inokuchi, MD, PhD, Kazuo Dan, MD, PhD

Blood (2011) 118 (21): 3592.

https://doi.org/10.1182/blood.V118.21.3592.3592

Published: 2011

Journal Articles

A Single Intramuscular Injection of AAV-8 Vector Expressing MDA7/IL-24 Efficiently Suppresses Tumor Growth Mediated by Multiple Anti-Cancer Mechanisms In Lymphoma Model Mice.

Nanya Wang, MD, Bai Fan, MD, Noriko Miyake, PhD, Koichi Miyake, MD, PhD, Takashi Shimada, MD, PhD

Blood (2010) 116 (21): 1474.

https://doi.org/10.1182/blood.V116.21.1474.1474

Published: 2010

Journal Articles

The Activated K-RAS Protein Accelerates Human Derived-MLL/AF4 Induced Leukemo-Lymphomogenicity In Transgenic Mice Model

Hayato Tamai, MD, Koichi Miyake, MD, PhD, Miyuki Takatori, Noriko Miyake, Hiroki Yamaguchi, MD, PhD, Kazuo Dan, MD, PhD, Takashi Shimada, MD, PHD, Koiti Inokuchi, PhD, MD

Blood (2010) 116 (21): 61.

https://doi.org/10.1182/blood.V116.21.61.61

Published: 2010

Journal Articles

MLL/AF4 Positive Acute Lymphoblastic Leukemia Has Resistance to Tumor Necrosis Factor-Alpha Caused by up-Regration of S100A6

Hayato Tamai, MD, Koichi Miyake, MD, PhD, Hiroki Yamaguchi, MD, PhD, Masahiro Okabe, MD, Kazuo Dan, MD, PhD, Koiti Inokuchi, PhD, MD, Takashi Shimada, MD, PHD

Blood (2010) 116 (21): 2477.

https://doi.org/10.1182/blood.V116.21.2477.2477

Published: 2010

Journal Articles

Establishment and Characterization of A New Leukemia Mouse Model Induced by MLL/AF4 Fusion Protein.

Hayato Tamai, Koichi Miyake, Noriko Miyake, Hiroki Yamaguchi, Kazuo Dan, Takashi Shimada, Koiti Inokuchi

Blood (2009) 114 (22): 3573.

https://doi.org/10.1182/blood.V114.22.3573.3573

Published: 2009

Journal Articles

Insertion of the 1.2kb Chicken β-Globin 5′HS4 Insulator Element in the LTR Inhibits HIV-1 Vector Mediated Transduction at the Early Infection Step.

Hideki Hanawa, MD, PhD, Takashi Shimada, MD, PhD

Blood (2007) 110 (11): 5137.

https://doi.org/10.1182/blood.V110.11.5137.5137

Published: 2007

Journal Articles

Hematopoiesis in Bone Marrow Regenerated from Adipose-Derived Stromal Cells.

Makoto Migita, MD, Atsushi Fujita, Rei Ogawa, MD, Takahiro Ueda, MD, Yoshitaka Fukunaga, MD, Takashi Shimada, MD

Blood (2007) 110 (11): 4108.

https://doi.org/10.1182/blood.V110.11.4108.4108

Published: 2007

Journal Articles

Hematopoiesis in Regenerated Bone Marrow on the Hydroxyapatite Scaffold.

Atsushi Fujita, Makoto Migita, MD, Takahiro Ueda, MD, Yoshitaka Fukunaga, MD, Takashi Shimada, MD

Blood (2007) 110 (11): 1419.

https://doi.org/10.1182/blood.V110.11.1419.1419

Published: 2007

Journal Articles

The Use of Hoechst Staining To Identify Hematopoietic and Other Adult Stem Cells.

Rei Ogawa, MD, PhD, Juri Fujimura, MD, PhD, Hidemitsu Sugihara, PhD, Hidenori Suzuki, MD, PhD, Hiko Hyakusoku, MD, PhD, Takashi Shimada, MD, PhD

Blood (2006) 108 (11): 4242.

https://doi.org/10.1182/blood.V108.11.4242.4242

Published: 2006

Journal Articles

Hematopoietic Microenvironment Regeneration Using Adipose-Derived Stem Cells.

Rei Ogawa, MD, PhD, Juri Fujimura, MD, PhD, Hiroshi Mizuno, MD, PhD, Hiko Hyakusoku, MD, PhD, Takashi Shimada, MD, PhD

Blood (2006) 108 (11): 4243.

https://doi.org/10.1182/blood.V108.11.4243.4243

Published: 2006

Journal Articles

MLL-AF4 and FLT3 Activation Synergize To Induce Multi Step Leukemogenesis.

Hiroki Yamaguchi, MD, PhD, Koiti Inokuchi, MD.PhD., Hideki Hanawa, MD.PhD., Kazuhiro Sawaguchi, Yoshio Mitamura, Naoya Uchida, MD., Mituharu Inami, MD., Takashi Shimada, MD.PhD., Kazuo Dan, MD.PhD.

Blood (2006) 108 (11): 4321.

https://doi.org/10.1182/blood.V108.11.4321.4321

Published: 2006

Journal Articles

Development of an In Vivo Exon Trapping Vector System To Detect Insertional Gene Activation by Lentiviral Vector.

Hideki Hanawa, MD, PhD, Takashi Shimada, MD, PhD

Blood (2005) 106 (11): 3059.

https://doi.org/10.1182/blood.V106.11.3059.3059

Published: 2005

Journal Articles

Leukemogenesis of the b2a2 Type p210 BCR/ABL in a Bone Marrow Transplantation Mouse Model Using a Lentivirus Vector.

Naoya Uchida, MD, Hideki Hanawa, MD, PhD, Koiti Inokuchi, MD, PhD, Kazuo Dan, MD, PhD, Takashi Shimada, MD, PhD

Blood (2005) 106 (11): 2875.

https://doi.org/10.1182/blood.V106.11.2875.2875

Published: 2005

Journal Articles

Comparison of Stem Cells Harvested from Adipose Tissue and Bone Marrow.

Rei Ogawa, MD, PhD, Juri Fujimura, MD, Hideki Hanawa, MD, PhD, Yukihiko Hirai, MD, PhD, Toshiyuki Kurai, MD, Hiroshi Mizuno, MD, PhD, Hiko Hyakusoku, MD, PhD, Takashi Shimada, MD, PhD

Blood (2005) 106 (11): 4221.

https://doi.org/10.1182/blood.V106.11.4221.4221

Published: 2005

Journal Articles

Regeneration of Hematopoietic Microenvironment (Bone Marrow) Using Adipose-Derived Stem Cells - The 2nd Report.

Rei Ogawa, MD, PhD, Juri Fujimura, MD, Hiroshi Mizuno, MD, PhD, Hiko Hyakusoku, MD, PhD, Takashi Shimada, MD, PhD

Blood (2005) 106 (11): 4304.

https://doi.org/10.1182/blood.V106.11.4304.4304

Published: 2005

Journal Articles

Regeneration of Bone Marrow from Adipose-Derived Stromal Cells - a Novel Approach for the Treatment of Fibroblastic Bone Marrow Diseases.

Rei Ogawa, MD, Hiroshi Mizuno, MD, Hiko Hyakusoku, MD, PhD, Makoto Migita, MD, PhD, Takashi Shimada, MD, PhD

Blood (2004) 104 (11): 2343.

https://doi.org/10.1182/blood.V104.11.2343.2343

Published: 2004

NARROW

Bone Marrow Cell Based Enzyme Replacement Prolongs Survival and Improves Disease Phenotypes In a Mouse Model Of Lethal Hypophosphatasia

Rescue of Lethal Hypophosphatasia Mice by Neonatal Ex Vivo Gene Therapy Using Lentivirally Transduced Bone Marrow Cells.

AAV8 vector expressing IL24 efficiently suppresses tumor growth mediated by specific mechanisms in MLL/AF4 -positive ALL model mice

The Clinical Features and Prognostic Impact of DNMT3A Gene Mutation in Japanese Patients with De Novo AML

Gene Mutations in Paired Initial Presentation and Relapse Samples From Acute Myeloid Leukemia Patients,

A Single Intramuscular Injection of AAV-8 Vector Expressing MDA7/IL-24 Efficiently Suppresses Tumor Growth Mediated by Multiple Anti-Cancer Mechanisms In Lymphoma Model Mice.

The Activated K-RAS Protein Accelerates Human Derived-MLL/AF4 Induced Leukemo-Lymphomogenicity In Transgenic Mice Model

MLL/AF4 Positive Acute Lymphoblastic Leukemia Has Resistance to Tumor Necrosis Factor-Alpha Caused by up-Regration of S100A6

Establishment and Characterization of A New Leukemia Mouse Model Induced by MLL/AF4 Fusion Protein.

Insertion of the 1.2kb Chicken β-Globin 5′HS4 Insulator Element in the LTR Inhibits HIV-1 Vector Mediated Transduction at the Early Infection Step.

Hematopoiesis in Bone Marrow Regenerated from Adipose-Derived Stromal Cells.

Hematopoiesis in Regenerated Bone Marrow on the Hydroxyapatite Scaffold.

The Use of Hoechst Staining To Identify Hematopoietic and Other Adult Stem Cells.

Hematopoietic Microenvironment Regeneration Using Adipose-Derived Stem Cells.

MLL-AF4 and FLT3 Activation Synergize To Induce Multi Step Leukemogenesis.

Development of an In Vivo Exon Trapping Vector System To Detect Insertional Gene Activation by Lentiviral Vector.

Leukemogenesis of the b2a2 Type p210 BCR/ABL in a Bone Marrow Transplantation Mouse Model Using a Lentivirus Vector.

Comparison of Stem Cells Harvested from Adipose Tissue and Bone Marrow.

Regeneration of Hematopoietic Microenvironment (Bone Marrow) Using Adipose-Derived Stem Cells - The 2nd Report.

Regeneration of Bone Marrow from Adipose-Derived Stromal Cells - a Novel Approach for the Treatment of Fibroblastic Bone Marrow Diseases.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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