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Journal Articles

Bone Marrow Niche Down-Regulates Mir-30 In Multiple Myeloma Cells to Promote Cancer Progression and Cancer Initiation by Targeting BCL9/Wnt Pathway.

Jian-Jun Zhao, M.D., Ph.D., Jianhong Lin, M.D., Zhangbo Chu, M.D., Qi Wang, Ph.D., Kohichi Takada, M.D., Ph.D., Mala Mani, Ph.D., Bryan Ciccarelli, Teru Hideshima, M.D., Ph.D., Tai Yu-Tzu, Ph.D., Jianguo Tao, MD, PhD, Steven P. Treon, MD, PhD, Nikhil C. Munshi, M.D., Kenneth C. Anderson, M.D., Ruben Carrasco, MD, PhD

Blood (2010) 116 (21): 1569.

https://doi.org/10.1182/blood.V116.21.1569.1569

Published: 2010

Journal Articles

HDAC Inhibition by LBH589 Affects Phenotype and Function of Human Dendritic Cells.

Weihua Song, MD, Yu-Tzu Tai, Ph.D., Ze Tian, Ph.D, Teru Hideshima, M.D., Ph.D., Dharminder Chauhan, Ph.D, Puru Nanjappa, MS, Mark A. Exley, Ph.D, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2009) 114 (22): 1646.

https://doi.org/10.1182/blood.V114.22.1646.1646

Published: 2009

Journal Articles

RFP2 Modulates 20S Proteasome Activity, NF Kappa B Activation, and Tumor Cell Growth in Multiple Myeloma.

Moshe E Gatt, MD, Mala Mani, PhD, Mikael Lerner, Teru Hideshima, M.D., Ph.D., Yunyu Zhang, Jui Dutta, Daniel E Carrasco, Alexei Protopopov, Olle Sangfelt, Dan Grander, MD, PhD, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., Kenneth C. Anderson, MD, Daniel Ruben Carrasco, M.D., Ph.D.

Blood (2009) 114 (22): 1786.

https://doi.org/10.1182/blood.V114.22.1786.1786

Published: 2009

Journal Articles

Molecular Sequaele of Activin A-Dependent Osteoblast Inhibition in Myeloma.

Blood (2009) 114 (22): 1789.

https://doi.org/10.1182/blood.V114.22.1789.1789

Published: 2009

Journal Articles

Significant Biological Role of Sp1 Transactivation in Myeloma: Potential Therapeutic Application.

Mariateresa Fulciniti, PhD, Teru Hideshima, M.D., Ph.D., Puru Nanjappa, MS, Scott Rodig, M.D., Ph.D., Samir B Amin, MBBS, Dheeraj Pelluru, PhD, Jagannath Pal, Rao Prabhala, PhD, Masood A Shammas, PhD, Pierfrancesco Tassone, Scott Mohrland, Kenneth C. Anderson, MD, Nikhil C. Munshi

Blood (2009) 114 (22): 1841.

https://doi.org/10.1182/blood.V114.22.1841.1841

Published: 2009

Journal Articles

CCL3 Impairs Osteoblast Function Via Downregulation of Osteocalcin.

Sonia Vallet, MD., Kishan Patel, Nileshwari Vaghela, Mariateresa Fulciniti, PhD, Petter Veiby, Teru Hideshima, M.D., Ph.D., Samantha Pozzi, MD, Loredana Santo, MD, Siddhartha Mukherjee, M.D., Diana Cirstea, MD, David T Scadden, MD, Kenneth C. Anderson, MD, Noopur Raje, MD.

Blood (2009) 114 (22): 739.

https://doi.org/10.1182/blood.V114.22.739.739

Published: 2009

Journal Articles

Bcl6 as a Novel Therapeutic Target in Multiple Myeloma (MM).

Teru Hideshima, M.D., Ph.D., Constantine S. Mitsiades, MD, PhD, Hiroshi Ikeda, MD, PhD, Dharminder Chauhan, PhD, Noopur Raje, M.D., Gullu Gorgun, PhD, Mariateresa Fulciniti, PhD, Diana Cirstea, MD, Giulia Perron, MD, Loredana Santo, M.D., Ayaka Hideshima, Klaus Podar, MD, MSc, PhD, Nikhil C. Munshi, MD, Paul Richardson, M.D., Ph.D., Daniel R. Carrasco, MD, PhD, Kenneth C. Anderson, MD

Blood (2009) 114 (22): 295.

https://doi.org/10.1182/blood.V114.22.295.295

Published: 2009

Journal Articles

Gadolinium Containing Contrast Agent Promotes Multiple Myeloma Cell Growth: Implication for Clinical Use of MRI in Myeloma.

Mariateresa Fulciniti, PhD, Swaminathan Sundararaman, Puru Nanjappa, MS, Samir B Amin, MBBS, Prajwal Chevireddy, Neriman Gokden, PhD, Kim Hiatt, Whitney High, Masood A Shammas, PhD, Rao Prabhala, PhD, Teru Hideshima, M.D., Ph.D., Pierfrancesco Tassone, Kenneth C. Anderson, MD, Sudhir V. Shah, Nikhil C. Munshi, MD

Blood (2009) 114 (22): 1809.

https://doi.org/10.1182/blood.V114.22.1809.1809

Published: 2009

Journal Articles

Targeting MEK1/2 Signaling Cascade by AS703026, a Novel Selective MEK1/2 Inhibitor, Induces Pleiotropic Anti-Myeloma Activity in Vitro and In Vivo.

Yu-Tzu Tai, Ph.D., Kihyun Kim, M.D., Xian-Feng Li, M.S., Mariateresa Fulciniti, Ph.D., Weihua Song, M.D., Sabikun Nahar, B.S., Peter Burger, B.S., Mathew J. Rumizen, Klaus Podar, M.D., Ph.D., Dharminder Chauhan, Ph.D, Teru Hideshima, M.D., Ph.D., Robert L Schlossman, M.D., Ph.D., Nikhil C. Munshi, Paul Richardson, M.D., Ph.D., Ann Clark, Ph.D., Janet Ogden, Ph.D., Goutopoulos Andreas, Ph.D., Luca Rastelli, Ph.D., Kenneth C. Anderson, MD

Blood (2009) 114 (22): 3848.

https://doi.org/10.1182/blood.V114.22.3848.3848

Published: 2009

Journal Articles

Panobinostat Inhibits JAK2/STAT3 Pathway in Multiple Myeloma.

Giulia Perrone, MD, Elisabetta Calabrese, MD., Teru Hideshima, M.D., Ph.D., Gullu Gorgun, PhD,, Ikeda Hiroshi, Diana Cristea, Loredana Santo, Hu Yiguo, Kenneth C. Anderson, MD

Blood (2009) 114 (22): 2849.

https://doi.org/10.1182/blood.V114.22.2849.2849

Published: 2009

Journal Articles

Promoting Osteoblastogenesis Using a Novel Dkk-1 Neutralizing Antibody in the Treatment of Multiple Myeloma Related Bone Disease

Samantha Pozzi, MD, Hua Yan, MD, Sonia Vallet, M.D., Nileshwari Vaghela, MS, Mariateresa Fulciniti, PhD, Diana Cirstea, MD, Loredana Santo, M.D., Siddhartha Mukherjee, MD, Teru Hideshima, M.D., Ph.D., Linda Schirtzinger, M.S., Stuart Kuhstoss, Nikhil C. Munshi, MD, Kenneth C Anderson, MD, David Scadden, MD, Noopur Raje, MD

Blood (2008) 112 (11): 2739.

https://doi.org/10.1182/blood.V112.11.2739.2739

Published: 2008

Journal Articles

Combination of Nab -Rapamycin and Perifosine Induces Synergistic Cytotoxicity and Antitumor Activity Via Autophagy and Apoptosis in Multiple Myeloma (MM)

Blood (2008) 112 (11): 3663.

https://doi.org/10.1182/blood.V112.11.3663.3663

Published: 2008

Journal Articles

CCL5 (RANTES) Is Suspected to Be the Key Chemokine to Understand the Bone Pathology of Multiple Myeloma

Kunio Hayashi, M.D., Ph.D., Shosaku Nomura, M.D., Ph.D., Seiji Hashimoto, Teru Hideshima, M.D., Ph.D.

Blood (2008) 112 (11): 5150.

https://doi.org/10.1182/blood.V112.11.5150.5150

Published: 2008

Journal Articles

A Novel Aurora-a Kinase Inhibitor MLN8237 Induces Cytotoxicity and Cell Cycle Arrest in Experimental Multiple Myeloma Models.

Gullu Gorgun, PhD, Elisabetta Calabrese, MD, Mala Mani, PhD, Teru Hideshima, M.D., Ph.D., Hiroshi Ikeda, MD, PhD, Giulia Perrone, MD, Loredana Santo, MD, Diana Cirstea, MD, Simona Blotta, Paul G. Richardson, MD, Jeffrey Ecsedy, Kenneth C. Anderson, MD

Blood (2008) 112 (11): 1719.

https://doi.org/10.1182/blood.V112.11.1719.1719

Published: 2008

Journal Articles

RGB 286638, a Novel Multi-Targeted Small Molecule Inhibitor, Induces Multiple Myeloma (MM) Cell Death through Abrogation of CDKDependent and Independent Survival Mechanisms

Diana Cirstea, M.D., Teru Hideshima, M.D., Ph.D., Samantha Pozzi, M.D., Sonia Vallet, M.D., Hiroshi Ikeda, M.D., Ph.D., Loredana Santo, M.D., Hannes Loferer, Nileshwari Vaghela, M.B.S., Yutaka Okawa, M.D., Ph.D., Giulia Perrone, M.D., Gullu Gorgun, Ph.D., Elisabetta Calabrese, M.D., Nikhil C. Munshi, MD, Kenneth C. Anderson, M.D., Noopur Raje, M.D.

Blood (2008) 112 (11): 2759.

https://doi.org/10.1182/blood.V112.11.2759.2759

Published: 2008

Journal Articles

AT7519, a Novel Small Molecule Multi-Cyclin Dependent Kinase Inhibitor, Induces Apoptosis in Multiple Myeloma VIA GSK3β

Loredana Santo, MD, Sonia Vallet, M.D., Teru Hideshima, M.D., Ph.D., Diana Cirstea, MD, Samantha Pozzi, MD, Nileshwari Vaghela, Hiroshi Ikeda, MD, PhD, Yutaka Okawa, MD, Gullu Gorgun, PhD, Giulia Perrone, MD, Elisabetta Calabrese, MD, Matthew S Squires, Marco Ladetto, MD, Nikhil C. Munshi, MD, Mario Boccadoro, Kenneth C. Anderson, MD, Noopur Raje, MD

Blood (2008) 112 (11): 251.

https://doi.org/10.1182/blood.V112.11.251.251

Published: 2008

Journal Articles

Molecular Profiling of Extramedullary and Medullary Plasmacytomas

Gabriela Motyckova, M.D., Ph.D., Aliyah Rahemtullah, M.D., Nileshwari Vaghela, M.S., Sonia Vallet, M.D., Adam Ackerman, Siddhartha Mukherjee, M.D., Ph.D., Samantha Pozzi, M.D., Loredana Santo, Ph.D., Diana Cirstea, M.D., Christiana Toomey, Ephraim P. Hochberg, M.D., Paola Dal Cin, Ph.D., Scott Rodig, M.D., Ph.D., Teru Hideshima, M.D., Ph.D., Kenneth C Anderson, M.D., Nikhil Munshi, M.D., Noopur Raje, M.D.

Blood (2008) 112 (11): 5111.

https://doi.org/10.1182/blood.V112.11.5111.5111

Published: 2008

Journal Articles

Restoration of Bone Balance Via Activin a Inhibition Results in Anti-Myeloma Activity

Blood (2008) 112 (11): 645.

https://doi.org/10.1182/blood.V112.11.645.645

Published: 2008

Journal Articles

Low Levels of Circulating CS1, a Newly Identified Multiple Myeloma (MM) Antigen for a Novel Humanized HuLuc63 Monoclonal Antibody, Is Detected in MM Patient Sera and Correlates with Active Disease.

Yu-Tzu Tai, PhD, Audie G. Rice, Ph.D., Marav Leiba, M.D., Xian-Feng Li, M.S., Peter Burger, B.S., Weihua Song, M.D., Rao Prabhala, Ph.D., Myles Dillon, B.S., Edie Tolan, Ph.D., Xanling Xie, Ph.D., Teru Hideshima, M.D., Ph.D., Noopur Raje, M.D., Paul Richardson, M.D., Nihkil C. Munshi, M.D., Arnon Nagler, M.D., Herve Avet-Loiseau, M.D., Daniel E.H. Afar, Ph.D., Kenneth C. Anderson, M.D.

Blood (2007) 110 (11): 1509.

https://doi.org/10.1182/blood.V110.11.1509.1509

Published: 2007

Journal Articles

Activation of B-Cell Maturation Antigen (BCMA) on Human Multiple Myeloma Cells by a Proliferation-Inducing Ligand (APRIL) Promotes Myeloma Cell Function in the Bone Marrow Microenvironment.

Merav Leiba, M.D., Jiangchun Xu, M.D., Ph.D., Weihua Song, M.D., Xian-Feng Li, M.S., Peter Burger, B.S., Jennifer Kordich, M.S., Linda Cassiano, B.A., Klaus Podar, M.D., Ph.D., Dharminder Chauhan, Ph.D., Teru Hideshima, M.D., Ph.D., Nikhil C. Munshi, M.D., Paul Richardson, M.D., Kenneth C. Anderson, M.D., Yu-Tzu Tai, PhD

Blood (2007) 110 (11): 1503.

https://doi.org/10.1182/blood.V110.11.1503.1503

Published: 2007

NARROW

Bone Marrow Niche Down-Regulates Mir-30 In Multiple Myeloma Cells to Promote Cancer Progression and Cancer Initiation by Targeting BCL9/Wnt Pathway.

HDAC Inhibition by LBH589 Affects Phenotype and Function of Human Dendritic Cells.

RFP2 Modulates 20S Proteasome Activity, NF Kappa B Activation, and Tumor Cell Growth in Multiple Myeloma.

Molecular Sequaele of Activin A-Dependent Osteoblast Inhibition in Myeloma.

Significant Biological Role of Sp1 Transactivation in Myeloma: Potential Therapeutic Application.

CCL3 Impairs Osteoblast Function Via Downregulation of Osteocalcin.

Bcl6 as a Novel Therapeutic Target in Multiple Myeloma (MM).

Gadolinium Containing Contrast Agent Promotes Multiple Myeloma Cell Growth: Implication for Clinical Use of MRI in Myeloma.

Targeting MEK1/2 Signaling Cascade by AS703026, a Novel Selective MEK1/2 Inhibitor, Induces Pleiotropic Anti-Myeloma Activity in Vitro and In Vivo.

Panobinostat Inhibits JAK2/STAT3 Pathway in Multiple Myeloma.

Promoting Osteoblastogenesis Using a Novel Dkk-1 Neutralizing Antibody in the Treatment of Multiple Myeloma Related Bone Disease

Combination of Nab -Rapamycin and Perifosine Induces Synergistic Cytotoxicity and Antitumor Activity Via Autophagy and Apoptosis in Multiple Myeloma (MM)

CCL5 (RANTES) Is Suspected to Be the Key Chemokine to Understand the Bone Pathology of Multiple Myeloma

A Novel Aurora-a Kinase Inhibitor MLN8237 Induces Cytotoxicity and Cell Cycle Arrest in Experimental Multiple Myeloma Models.

RGB 286638, a Novel Multi-Targeted Small Molecule Inhibitor, Induces Multiple Myeloma (MM) Cell Death through Abrogation of CDKDependent and Independent Survival Mechanisms

AT7519, a Novel Small Molecule Multi-Cyclin Dependent Kinase Inhibitor, Induces Apoptosis in Multiple Myeloma VIA GSK3β

Molecular Profiling of Extramedullary and Medullary Plasmacytomas

Restoration of Bone Balance Via Activin a Inhibition Results in Anti-Myeloma Activity

Low Levels of Circulating CS1, a Newly Identified Multiple Myeloma (MM) Antigen for a Novel Humanized HuLuc63 Monoclonal Antibody, Is Detected in MM Patient Sera and Correlates with Active Disease.

Activation of B-Cell Maturation Antigen (BCMA) on Human Multiple Myeloma Cells by a Proliferation-Inducing Ligand (APRIL) Promotes Myeloma Cell Function in the Bone Marrow Microenvironment.

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American Society of Hematology

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American Society of Hematology

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