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Journal Articles

Transcriptome Alterations of Isolated Primary Bone Marrow Endothelial Cells Provide Insigt to MGUS and Multiple Myeloma Pathobiology

Sandro Bräunig, MSc, Dimitra Zacharaki, PhD, Hongzhe Li, PhD, Hooi Ching Lim, PhD, Stefan Lang, PhD, Thoas Fioretos, MD PhD Prof., Stefan Scheding, MD

Blood (2019) 134 (Supplement_1): 4373.

https://doi.org/10.1182/blood-2019-128024

Published: 2019

Journal Articles

AML Xenografts Undergo Extensive Clonal Competition and Unmask Rare Clones in Patient Samples

Carl Sandén, PhD, Henrik Lilljebjörn, PhD, Christina Orsmark-Pietras, PhD, Karim Saba, MSc, Carl Högberg, PhD, Marianne Rissler, MSc, Vladimir Lazarevic, MD PhD, Gunnar Juliusson, MD PhD, Helena Ågerstam, PhD, Thoas Fioretos, MD PhD

Blood (2018) 132 (Supplement 1): 2621.

https://doi.org/10.1182/blood-2018-99-110497

Published: 2018

Journal Articles

CDK8 Inhibitor SEL120-34A Has Therapeutic Efficacy in Murine and Human Acute Myeloid Leukemia Models

Blood (2018) 132 (Supplement 1): 1520.

https://doi.org/10.1182/blood-2018-99-111859

Published: 2018

Journal Articles

Transcriptome Alterations of Prospectively Isolated Bone Marrow Stromal Cells Provide Potential Cues to MGUS and Multiple Myeloma Pathobiology

Dimitra Zacharaki, Roshanak Ghazanfari, PhD, Hongzhe Li, PhD, Hooi Ching Lim, PhD, Sofia Von Palffy, Shamit Soneji, PhD, Thoas Fioretos, MD PhD, Stefan Scheding, MD

Blood (2017) 130 (Supplement 1): 4375.

https://doi.org/10.1182/blood.V130.Suppl_1.4375.4375

Published: 2017

Journal Articles

The Proteogenomic Landscape of High Hyperdiploid and ETV6/RUNX1-Positive Childhood Acute Lymphoblastic Leukemia

Minjun Yang, Mattias Vesterlund, Ioannis Siavelis, Eleanor Woodward, Naveen Ravi, Henrik Lilljebjörn, MSc, Thoas Fioretos, MD PhD, Janne Lehtiö, Kajsa Paulsson

Blood (2017) 130 (Supplement 1): 1433.

https://doi.org/10.1182/blood.V130.Suppl_1.1433.1433

Published: 2017

Journal Articles

Monitoring Leukemic Mutations Using Ultrasensitive IBSAFE Digital Droplet Analysis Predicts Relapse of Acute Myeloid Leukemia

Louise Pettersson, MD, Yilun Chen, MSc, Anthony M George, MSc, Christina Orsmark-Pietras, PhD, Henrik Lilljebjörn, MSc, Robert Rigo, MSc, Vladimir Lazarevic, MD PhD, Thoas Fioretos, MD PhD, Gunnar Juliusson, MD PhD, Mats Ehinger, MD PhD, Lao H Saal, MD PhD

Blood (2017) 130 (Supplement 1): 3951.

https://doi.org/10.1182/blood.V130.Suppl_1.3951.3951

Published: 2017

Journal Articles

Modeling Chronic Myeloid Leukemia in Immunodeficient Mice Reveals an Inflammatory State with Expansion of Aberrant Mast Cells and Accumulation of Pre B Cells

Maria Askmyr, PhD, Helena Agerstam, PhD, Henrik Lilljebjörn, PhD, Nils Hansen, PhD, Christine Karlsson, PhD, Niklas Landberg, Carl Hogberg, PhD, Carin Lassen, Msc, Marianne Rissler, Johan Richter, MD PhD, Mats Ehinger, MD PhD, Marcus Jaras, PhD, Thoas Fioretos, MD PhD

Blood (2014) 124 (21): 3132.

https://doi.org/10.1182/blood.V124.21.3132.3132

Published: 2014

Journal Articles

Comprehensive Genetic Characterization of Pediatric T-Cell Acute Lymphoblastic Leukemia

Kristina Karrman, MD PhDstudent, Anders Castor, Mikael Behrendtz, MD, Erik Forestier, Linda Olsson, PhDstudent, Mats Ehinger, MD PhD, Andrea Biloglav, Thoas Fioretos, MD PhD, Kajsa Paulsson, MSc, PhD, Bertil Johansson, MD PhD

Blood (2014) 124 (21): 1084.

https://doi.org/10.1182/blood.V124.21.1084.1084

Published: 2014

Journal Articles

Toll-like Receptor 1 Is a Candidate Therapeutic Target in Acute Myeloid Leukemia

Mia Eriksson, Pablo Peña, Marion Chapellier, PhD, Carl Högberg, PhD, Thoas Fioretos, MD PhD, Benjamin L Ebert, MD PhD, Marcus Järås, PhD

Blood (2014) 124 (21): 5782.

https://doi.org/10.1182/blood.V124.21.5782.5782

Published: 2014

Journal Articles

Upregulation Of IL1RAP On Human Progenitor/Stem Cells Induces Features Of a Myeloproliferative Disorder In Mice

Nils Hansen, Kristian Reckzeh, PhD, Helena Agerstam, PhD, Maria Askmyr, PhD, Sandra Gordon, Marianne Rissler, Carl Högberg, PhD, Johan Richter, MD, PhD, Marcus Järås, PhD, Thoas Fioretos, MD, PhD

Blood (2013) 122 (21): 1650.

https://doi.org/10.1182/blood.V122.21.1650.1650

Published: 2013

Journal Articles

Strong Therapeutic Effect Of Anti-IL1RAP Immunotherapy In a Xenograft Model Of Acute Myeloid Leukemia

Helena Agerstam, PhD, Maria Askmyr, PhD, Nils Hansen, Marianne Rissler, Gunnar Juliusson, MD, PhD, Johan Richter, MD, PhD, Mark Wunderlich, MS, Marcus Järås, PhD, James C. Mulloy, PhD, Thoas Fioretos, MD PhD

Blood (2013) 122 (21): 3954.

https://doi.org/10.1182/blood.V122.21.3954.3954

Published: 2013

Journal Articles

Leukemic Stem Cell Quantification Is Of Prognostic Value In Newly Diagnosed Patients In Chronic Phase Chronic Myeloid Leukemia (CML-CP) Receiving Nilotinib Therapy: Results From The ENEST1st Stem Cell Substudy

Noortje Thielen, MD, Johan Richter, MD, PhD, Gisela Barbany, MD PhD, Thoas Fioretos, MD PhD, Frank Giles, MD MB, Bjorn T Gjertsen, MD PhD, Andreas Hochhaus, MD, Gert J. Ossenkoppele, MD PhD, Kimmo Porkka, MD, PhD, Gerrit Jan Schuurhuis, PhD, Sieghart Sopper, PhD, Leif Stenke, MD, PhD, Sara Thunberg, PhD, Dominik Wolf, MD, Jeroen Janssen, MD PhD, Satu Mustjoki, MD, PhD

Blood (2013) 122 (21): 649.

https://doi.org/10.1182/blood.V122.21.649.649

Published: 2013

Journal Articles

Whole Genome Sequence Analysis of 22 MLL Rearranged Infant Acute Lymphoblastic Leukemias Reveals Remarkably Few Somatic Mutations: A Report From the St Jude Children‘s Research Hospital - Washington University Pediatric Cancer Genome Project

Blood (2011) 118 (21): 69.

https://doi.org/10.1182/blood.V118.21.69.69

Published: 2011

Journal Articles

Socs2 Is Dispensable for BCR/ABL1-Induced Chronic Myeloid Leukemia-Like Disease in Mice and for Normal Hematopoietic Stem Cell Function,

Nils Hansen, Helena Agerstam, PhD, Martin Wahlestedt, Mats Ehinger, MD, PhD, Petra Johnels, PhD, Jun Ishiko, PhD, Junia V. Melo, MD, PhD, Warren S Alexander, PhD, David Bryder, Marcus Järås, PhD, Thoas Fioretos, MD, PhD

Blood (2011) 118 (21): 3743.

https://doi.org/10.1182/blood.V118.21.3743.3743

Published: 2011

Journal Articles

Favorable Therapeutic Responses in Newly Diagnosed CML-CP Patients Induced by Dasatinib Are Reflected At the CD34+CD38+ Progenitor Cell but Not At the CD34+CD38− Stem Cell Level: Results From Randomized NordCML006 Study

Blood (2011) 118 (21): 784.

https://doi.org/10.1182/blood.V118.21.784.784

Published: 2011

Journal Articles

The Proportion of Ph+ CD34 + CD38 neg Leukemic Stem Cells In the Bone Marrow of Newly Diagnosed Patients with Chronic Myeloid Leukemia (CML) In Chronic Phase (CP) Is Variable and Correlates with High Sokal Risk, High Leukocyte Count, Low Hemoglobin Concentration, Splenomegaly and Increased Hematological Toxicity During Initial TKI-Therapy. Data From a Randomized Phase II NordCML006 Study

Blood (2010) 116 (21): 667.

https://doi.org/10.1182/blood.V116.21.667.667

Published: 2010

Journal Articles

SMAD4 Sequestrates HOXA9 to Protect Hematopoietic Stem Cells Against Leukemia Transformation

Ronan Quere, PhD, Göran Karlsson, PhD, Falk Hertwig, Marianne Rissler, Beata Lindqvist, Thoas Fioretos, MD, PhD, Peter Vandenberghe, MD, PhD, Marilyn L. Slovak, PhD, Kristian Reckzeh, Jörg Cammenga, MD, PhD, Stefan Karlsson, MD, PhD

Blood (2010) 116 (21): 3153.

https://doi.org/10.1182/blood.V116.21.3153.3153

Published: 2010

Journal Articles

Relapsed Childhood High Hyperdiploid Acute Lymphoblastic Leukemia: Genome-Wide Screening Reveals the Presence of Preleukemic Ancestral Clones and the Secondary Nature of Microdeletions and RTK-RAS Mutations.

Josef Davidsson, PhD, Kajsa Paulsson, PhD, David Lindgren, PhD, Henrik Lilljebjörn, MS, Tracy Chaplin, MS, Erik Forestier, MD, PhD, Mette K Andersen, MD, PhD, Ann Nordgren, MD, PhD, Richard Rosenquist, MD, PhD, Thoas Fioretos, MD, PhD, Bryan D Young, PhD, Bertil Johansson, MD, PhD

Blood (2009) 114 (22): 2591.

https://doi.org/10.1182/blood.V114.22.2591.2591

Published: 2009

Journal Articles

High Resolution Genome-Wide Array-Based Comparative Genome Hybridization Reveals Cryptic Chromosome Changes in AML and MDS Cases with Trisomy 8 as the Sole Cytogenetic Aberration.

Kajsa Paulsson, PhD, Markus Heidenblad, PhD, Bodil Strombeck, Ake Borg, PhD, Thoas Fioretos, MD, PhD, Bertil Johansson, MD, PhD

Blood (2005) 106 (11): 2847.

https://doi.org/10.1182/blood.V106.11.2847.2847

Published: 2005

Journal Articles

Evidence for a Single Step Mechanism in the Origin of Hyperdiploid Childhood Acute Lymphoblastic Leukemia.

Kajsa Paulsson, Helena Morse, MD, Thoas Fioretos, MD, PhD, Mikael Behrendtz, MD, Bodil Strombeck, Felix Mitelman, MD, PhD, Bertil Johansson, MD, PhD

Blood (2004) 104 (11): 1966.

https://doi.org/10.1182/blood.V104.11.1966.1966

Published: 2004

NARROW

Transcriptome Alterations of Isolated Primary Bone Marrow Endothelial Cells Provide Insigt to MGUS and Multiple Myeloma Pathobiology

AML Xenografts Undergo Extensive Clonal Competition and Unmask Rare Clones in Patient Samples

CDK8 Inhibitor SEL120-34A Has Therapeutic Efficacy in Murine and Human Acute Myeloid Leukemia Models

Transcriptome Alterations of Prospectively Isolated Bone Marrow Stromal Cells Provide Potential Cues to MGUS and Multiple Myeloma Pathobiology

The Proteogenomic Landscape of High Hyperdiploid and ETV6/RUNX1-Positive Childhood Acute Lymphoblastic Leukemia

Monitoring Leukemic Mutations Using Ultrasensitive IBSAFE Digital Droplet Analysis Predicts Relapse of Acute Myeloid Leukemia

Modeling Chronic Myeloid Leukemia in Immunodeficient Mice Reveals an Inflammatory State with Expansion of Aberrant Mast Cells and Accumulation of Pre B Cells

Comprehensive Genetic Characterization of Pediatric T-Cell Acute Lymphoblastic Leukemia

Toll-like Receptor 1 Is a Candidate Therapeutic Target in Acute Myeloid Leukemia

Upregulation Of IL1RAP On Human Progenitor/Stem Cells Induces Features Of a Myeloproliferative Disorder In Mice

Strong Therapeutic Effect Of Anti-IL1RAP Immunotherapy In a Xenograft Model Of Acute Myeloid Leukemia

Leukemic Stem Cell Quantification Is Of Prognostic Value In Newly Diagnosed Patients In Chronic Phase Chronic Myeloid Leukemia (CML-CP) Receiving Nilotinib Therapy: Results From The ENEST1st Stem Cell Substudy

Whole Genome Sequence Analysis of 22 MLL Rearranged Infant Acute Lymphoblastic Leukemias Reveals Remarkably Few Somatic Mutations: A Report From the St Jude Children‘s Research Hospital - Washington University Pediatric Cancer Genome Project

Socs2 Is Dispensable for BCR/ABL1-Induced Chronic Myeloid Leukemia-Like Disease in Mice and for Normal Hematopoietic Stem Cell Function,

Favorable Therapeutic Responses in Newly Diagnosed CML-CP Patients Induced by Dasatinib Are Reflected At the CD34+CD38+ Progenitor Cell but Not At the CD34+CD38− Stem Cell Level: Results From Randomized NordCML006 Study

SMAD4 Sequestrates HOXA9 to Protect Hematopoietic Stem Cells Against Leukemia Transformation

Relapsed Childhood High Hyperdiploid Acute Lymphoblastic Leukemia: Genome-Wide Screening Reveals the Presence of Preleukemic Ancestral Clones and the Secondary Nature of Microdeletions and RTK-RAS Mutations.

High Resolution Genome-Wide Array-Based Comparative Genome Hybridization Reveals Cryptic Chromosome Changes in AML and MDS Cases with Trisomy 8 as the Sole Cytogenetic Aberration.

Evidence for a Single Step Mechanism in the Origin of Hyperdiploid Childhood Acute Lymphoblastic Leukemia.

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American Society of Hematology

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American Society of Hematology

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