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Thomas Chittenden
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Journal Articles

IMGN632: A CD123-Targeting Antibody-Drug Conjugate (ADC) with a Novel DNA-Alkylating Payload, Is Highly Active and Prolongs Survival in Acute Myeloid Leukemia (AML) Xenograft Models

Sharlene Adams, PhD, Alan Wilhelm, Lauren Harvey, MS, Chen Bai, Nicholas Yoder, PhD, Yelena Kovtun, PhD, Thomas Chittenden, PhD, Jan Pinkas, PhD
Journal: Blood
Blood (2016) 128 (22): 2832.
https://doi.org/10.1182/blood.V128.22.2832.2832
Published: 2016
Journal Articles

A CD123-Targeting Antibody-Drug Conjugate (ADC), IMGN632, Designed to Eradicate Acute Myeloid Leukemia (AML) Cells While Sparing Normal Bone Marrow Cells

Yelena Kovtun, PhD, Gregory Jones, Charlene Audette, Lauren Harvey, MS, Baudouin Gerard, PhD, Alan Wilhelm, Chen Bai, Sharlene Adams, PhD, Victor S Goldmacher, PhD, Ravi Chari, PhD, Thomas Chittenden, PhD
Journal: Blood
Blood (2016) 128 (22): 768.
https://doi.org/10.1182/blood.V128.22.768.768
Published: 2016
Journal Articles

A novel anti-CD37 antibody-drug conjugate with multiple anti-tumor mechanisms for the treatment of B-cell malignancies

Jutta Deckert, Peter U. Park, Sharon Chicklas, Yong Yi, Min Li, Katharine C. Lai, Michele F. Mayo, Christina N. Carrigan, Hans K. Erickson, Jan Pinkas, Robert J. Lutz, Thomas Chittenden, John M. Lambert
Journal: Blood
Blood (2013) 122 (20): 3500–3510.
https://doi.org/10.1182/blood-2013-05-505685
Published: 2013
Journal Articles

Potent B-Cell Depletion by IMGN529, a CD37-Targeting Antibody-Maytansinoid Conjugate for the Treatment of B-Cell Malignancies,

Jutta Deckert, Ph.D., Sharon Chicklas, Yong Yi, Min Li, Jan Pinkas, Ph. D., Thomas Chittenden, Ph.D., Robert J. Lutz, PhD, Peter U. Park, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 3726.
https://doi.org/10.1182/blood.V118.21.3726.3726
Published: 2011
Journal Articles

SAR650984: A Potent Anti-CD38 Therapeutic Antibody with Three Mechanisms of Action (Apoptosis, ADCC, CDC) for Hematological Malignancies

Peter U. Park, Véronique Blanc, Jutta Deckert, Pascale Lejeune, Laura M. Bartle, Anna Skaletskaya, Michele F. Mayo, Chonghui Zhang, Marie-Cécile Wetzel, Daniel J. Tavares, Robert J. Lutz, Thomas Chittenden, Marie-Christine Bissery, John M. Lambert, Victor S. Goldmacher
Journal: Blood
Blood (2008) 112 (11): 2756.
https://doi.org/10.1182/blood.V112.11.2756.2756
Published: 2008