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Timothy J. Kottke
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Journal Articles

Effects of the Bcr/abl kinase inhibitors STI571 and adaphostin (NSC 680410) on chronic myelogenous leukemia cells in vitro

Benjamin M. F. Mow, Joya Chandra, Phyllis A. Svingen, Christopher G. Hallgren, Ellen Weisberg, Timothy J. Kottke, Ven L. Narayanan, Mark R. Litzow, James D. Griffin, Edward A. Sausville, Ayalew Tefferi, Scott H. Kaufmann
Journal: Blood
Blood (2002) 99 (2): 664–671.
https://doi.org/10.1182/blood.V99.2.664
Published: 2002
Journal Articles

Enhanced ceramide generation and induction of apoptosis in human leukemia cells exposed to DT 388 –granulocyte-macrophage colony-stimulating factor (GM-CSF), a truncated diphtheria toxin fused to human GM-CSF

Alex Senchenkov, Tie-Yan Han, Hongtao Wang, Arthur E. Frankel, Timothy J. Kottke, Scott H. Kaufmann, Myles C. Cabot
Journal: Blood
Blood (2001) 98 (6): 1927–1934.
https://doi.org/10.1182/blood.V98.6.1927
Published: 2001
Journal Articles

Clinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: a phase 1 clinical-laboratory correlative trial

Clinical Trials & Observations
Judith E. Karp, Jeffrey E. Lancet, Scott H. Kaufmann, David W. End, John J. Wright, Kees Bol, Ivan Horak, Michael L. Tidwell, Jane Liesveld, Timothy J. Kottke, Dawn Ange, Laxmi Buddharaju, Ivana Gojo, W. Edward Highsmith, Robert T. Belly, Raymond J. Hohl, Mary Ellen Rybak, Alain Thibault, Joseph Rosenblatt
Journal: Blood
Blood (2001) 97 (11): 3361–3369.
https://doi.org/10.1182/blood.V97.11.3361
Published: 2001
Journal Articles

Phosphorylated Forms of Activated Caspases Are Present in Cytosol From HL-60 Cells During Etoposide-Induced Apoptosis

Luis M. Martins, Timothy J. Kottke, Scott H. Kaufmann, William C. Earnshaw
Journal: Blood
Blood (1998) 92 (9): 3042–3049.
https://doi.org/10.1182/blood.V92.9.3042
Published: 1998
Journal Articles

Comparison of Caspase Activation and Subcellular Localization in HL-60 and K562 Cells Undergoing Etoposide-Induced Apoptosis

Luis M. Martins, Peter W. Mesner, Timothy J. Kottke, Guriqbal S. Basi, Sukanto Sinha, Jay S. Tung, Phyllis A. Svingen, Benjamin J. Madden, Atsushi Takahashi, Daniel J. McCormick, William C. Earnshaw, Scott H. Kaufmann
Journal: Blood
Blood (1997) 90 (11): 4283–4296.
https://doi.org/10.1182/blood.V90.11.4283
Published: 1997
Journal Articles

Comparison of Apoptosis in Wild-Type and Fas-Resistant Cells: Chemotherapy-Induced Apoptosis Is Not Dependent on Fas/Fas Ligand Interactions

Christine M. Eischen, Timothy J. Kottke, Luis M. Martins, Guriqbal S. Basi, Jay S. Tung, William C. Earnshaw, Paul J. Leibson, Scott H. Kaufmann
Journal: Blood
Blood (1997) 90 (3): 935–943.
https://doi.org/10.1182/blood.V90.3.935
Published: 1997