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Journal Articles

Signaling Gene Mutations Are Characterized By Diverse Patterns of Expansion and Contraction during Progression from MDS to Secondary AML

Andrew J Menssen, BA, Ajay Khanna, Christopher A Miller, PhD, Gue Su Chang, PhD, Jin J Shao, Sridhar Nonavinkere Srivatsan, MS, Joshua Robinson, Michelle O'Laughlin, Catrina Fronick, BS, Robert Fulton, MS, Kimberly J Brendel, Sharon E Heath, Peter Westervelt, MDPhD, John F. DiPersio, MD PhD, Daniel C. Link, MD, Meagan A. Jacoby, Eric Duncavage, MD, Timothy J Ley, MD, Matthew J. Walter, MD

Blood (2020) 136 (Supplement 1): 2–3.

https://doi.org/10.1182/blood-2020-140394

Published: 2020

Journal Articles

Molecular Profiling of Decitabine Response in MDS and AML Patients

Pawan Kumar Upadhyay, PhD, Jeremy Beales, MS, Nakul Kumar Shah, MD, Christopher A Miller, PhD, Allegra A Petti, PhD, Daniel C. Link, MD, Timothy J Ley, MD, John Welch, MDPhD

Blood (2020) 136 (Supplement 1): 40.

https://doi.org/10.1182/blood-2020-141292

Published: 2020

Journal Articles

Comparison of Deep Whole Exome Versus Targeted Gene Sequencing for Assessment of Persistent Molecular Disease in Acute Myeloid Leukemia Samples

Michael Slade, MDMS, Michelle O'Laughlin, Robert S Fulton, Eric J. Duncavage, MD, Timothy J Ley, MD, Meagan A. Jacoby, MD, David H Spencer, MD

Blood (2020) 136 (Supplement 1): 6–7.

https://doi.org/10.1182/blood-2020-133279

Published: 2020

Journal Articles

Gata2 Expression and Function in PML-RARA- driven Preleukemia and APL

Casey D.S. Katerndahl, PhD, Timothy J Ley, MD, Michelle A Cai, Timothy P Rooney, Jr., Sai Mukund Ramakrishnan, MS, Sridhar Nonavinkere Srivatsan, MS, Christopher A Miller, PhD

Blood (2019) 134 (Supplement_1): 534.

https://doi.org/10.1182/blood-2019-131883

Published: 2019

Journal Articles

DNMT3A R882 Alters the Epigenome of Hematopoietic Cells

Amanda M Smith, PhD, Taylor LaValle, BS, Shamika Ketkar, PhD, Sai Mukund Ramakrishnan, MS, Christopher A Miller, PhD, Timothy J Ley, MD

Blood (2019) 134 (Supplement_1): 112.

https://doi.org/10.1182/blood-2019-129003

Published: 2019

Journal Articles

The Molecular Basis of Long First Remissions in Normal Karyotype AML Patients

Francesca Ferraro, MD PhD, Christopher A Miller, PhD, Amy Abdalla, Nichole Helton, Nathan Salomonis, PhD, Robert S Fulton, Catrina Fronick, BS, Sharon E Heath, Peter Westervelt, MD PhD, Timothy J Ley, MD

Blood (2019) 134 (Supplement_1): 3827.

https://doi.org/10.1182/blood-2019-122967

Published: 2019

Journal Articles

Whole Genome Bisulfite Sequencing of 63 Primary AML Samples Identifies a Unique DNA Hypermethylation Signature for Mutant IDH1/2 Cases That Is Different from That of TET2 Mutant AML

Ellie Wilson, BS, Nichole Helton, Catrina Fronick, BS, Robert Fulton, MS, John S. Welch, MD PhD, Timothy J Ley, MD, David H Spencer, MD

Blood (2019) 134 (Supplement_1): 3755.

https://doi.org/10.1182/blood-2019-122340

Published: 2019

Journal Articles

Evidence for Complete Mutation Clearance in Normal Karyotype AML Patients with Very Long (> 5 years) Remissions after Chemotherapy Alone

Francesca Ferraro, MD PhD, Christopher A Miller, PhD, Nichole Helton, Robert S Fulton, Catrina Fronick, BS, Sharon E Heath, Peter Westervelt, MD PhD, Timothy J Ley, MD

Blood (2018) 132 (Supplement 1): 1503.

https://doi.org/10.1182/blood-2018-99-117288

Published: 2018

Journal Articles

Improving Risk Assessment of AML with a Precision Genomic Strategy to Assess Mutation Clearance

Blood (2018) 132 (Supplement 1): 5277.

https://doi.org/10.1182/blood-2018-99-114979

Published: 2018

Journal Articles

Direct Detection of Expressed Mutations in AML Cells Using Single Cell RNA-Sequencing, and Its Impact on Defining Sources of Expression Heterogeneity

Allegra A Petti, PhD, Stephen R Williams, PhD, Christopher A Miller, PhD, Ian T Fiddes, PhD, David Chen, MD PhD, Sridhar Nonavinkere Srivatsan, MS, Catrina Fronick, BS, Robert Fulton, MS, Deanna M Church, PhD, Timothy J Ley, MD

Blood (2018) 132 (Supplement 1): 1314.

https://doi.org/10.1182/blood-2018-99-119075

Published: 2018

Journal Articles

Generation and Characterization of Murine Allogeneic T Cell Resistant APL Cells

Ezhilarasi Chendamarai, PhD, Michael P Rettig, PhD, Gue Su Chang, PhD, Allegra A Petti, PhD, Christopher A Miller, PhD, Julie Ritchey, Lukas D Wartman, MD, Timothy J Ley, MD, John F DiPersio, MD PhD

Blood (2017) 130 (Supplement 1): 3170.

https://doi.org/10.1182/blood.V130.Suppl_1.3170.3170

Published: 2017

Journal Articles

Clonal Evolution and Relapse in Adult De Novo Acute Myeloid Leukemia

Timothy J. Ley, MD

Blood (2017) 130 (Supplement 1): SCI-40.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-40.SCI-40

Published: 2017

Journal Articles

Ultra-Deep Sequencing As a Predictive Tool for MDS Progression after Allogeneic Hematopoietic Cell Transplant

Eric J. Duncavage, MD, Meagan Jacoby, MD PhD, Gue Su Chang, PhD, Christopher A Miller, PhD, Natasha Edwin, MD, Geoffrey L. Uy, MD, Joshua Robinson, Haley J Abel, PhD, Jin Shao, Kevin Elliot, Robert Fulton, Catrina Fronick, Michelle O'Laughlin, John F DiPersio, MD PhD, Timothy J Ley, MD, Kathryn Trinkaus, PhD, Timothy Aaron Graubert, MD, Matthew J. Walter, MD

Blood (2017) 130 (Supplement 1): 1669.

https://doi.org/10.1182/blood.V130.Suppl_1.1669.1669

Published: 2017

Journal Articles

Clonal Evolution of Acute Myeloid Leukemia Following Allogeneic Stem Cell Transplantation

Matt Christopher, MD PhD, Allegra A. Petti, PhD, Christopher Miller, PhD, Lukas D. Wartman, MD, Jacqueline E. Payton, MD PhD, Sharon Heath, Robert Fulton, John S. Welch, MD PhD, Matthew J. Walter, MD, Peter Westervelt, MD PhD, Daniel C. Link, MD, Richard K Wilson, PhD, Timothy J. Ley, MD, John F. DiPersio, MD, PhD

Blood (2016) 128 (22): 1528.

https://doi.org/10.1182/blood.V128.22.1528.1528

Published: 2016

Journal Articles

DNMT3A -Dependent DNA Methylation May Act As a Tumor Suppressor-Not a Tumor Promoter-during AML Progression

David Spencer, MDPhD, David Russler-Germain, Nichole M Helton, B.S., Tamara L Lamprecht, B.S., Marwan Shinawi, MD, Peter Westervelt, MD PhD, Jacqueline E. Payton, MD PhD, Robert S. Fulton, PhD, Richard K Wilson, PhD, Matthew J. Walter, MD, Daniel C. Link, MD, John F. DiPersio, MD, PhD, Timothy J. Ley, MD

Blood (2016) 128 (22): 1050.

https://doi.org/10.1182/blood.V128.22.1050.1050

Published: 2016

Journal Articles

Dynamic Changes in MDS Clonal Architecture Following Allogeneic Stem Cell Transplant

Meagan A. Jacoby, MD PhD, Eric J. Duncavage, MD, Gue Su Chang, PhD, Christopher A. Miller, PhD, Jin Shao, Kevin Elliott, Robert S. Fulton, PhD, Catrina Fronick, Michelle O'Laughlin, Daniel C. Link, MD, John F DiPersio, MD PhD, Peter Westervelt, MD PhD, Timothy J. Ley, MD, Timothy A. Graubert, MD, Matthew J. Walter, MD, Richard K Wilson, PhD

Blood (2016) 128 (22): 5506.

https://doi.org/10.1182/blood.V128.22.5506.5506

Published: 2016

Journal Articles

Obesity As a Risk Factor for Acute Promyelocytic Leukemia. Results from Population and Case-Control Studies Across Western Countries and Correlation with Gene Expression in the TCGA

Luca Mazzarella, MD PhD, Edoardo Botteri, PhD, Anthony Matthews, MPhil, Davide Disalvatore, PhD, Vincenzo Bagnardi, PhD, Massimo Breccia, MD, Pau Montesinos, MD PhD, Teresa Bernal, MD PhD, Cristina Gil, MD, Timothy J. Ley, MD, Miguel A. Sanz, MD PhD, Krishnan Bhaskaran, PhD, Francesco Lo Coco, MD, Pier Giuseppe Pelicci, MD

Blood (2016) 128 (22): 448.

https://doi.org/10.1182/blood.V128.22.448.448

Published: 2016

Journal Articles

MIR142 Loss-of-Function Mutations Promote Leukemogenesis through Derepression of ASH1L Resulting in Increased HOX Gene Expression

Juo-Chin Yao, BS, Terrence Neal Wong, MD PhD, Maria Trissal, MD PhD, Rahul Ramaswamy, Yaping Sun, MD PhD, Timothy J. Ley, MD, Pavan R. Reddy, MD, Daniel C. Link, MD

Blood (2016) 128 (22): 2718.

https://doi.org/10.1182/blood.V128.22.2718.2718

Published: 2016

Journal Articles

Reprogramming of Leukemic and Pre-Leukemic Cells from Primary Human De Novo Acute Myeloid Leukemia Samples into Induced Pluripotent Stem (iPS) Cells

David Spencer, MDPhD, Daniel R. George, Jeffery M. Klco, MDPhD, Timothy J. Ley, MD

Blood (2015) 126 (23): 1862.

https://doi.org/10.1182/blood.V126.23.1862.1862

Published: 2015

Journal Articles

Loss-of-Function Mutations of MIR142 May Contribute to Leukemogenesis By Expanding the Pool of Myeloid-Biased HSCs

Juo-Chin Yao, BS, Terrence Neal Wong, MDPhD, Maria Trissal, BS, Yaping Sun, MD PhD, Timothy J. Ley, MD, Pavan Reddy, MD, Daniel C. Link, MD

Blood (2015) 126 (23): 1254.

https://doi.org/10.1182/blood.V126.23.1254.1254

Published: 2015

NARROW

Signaling Gene Mutations Are Characterized By Diverse Patterns of Expansion and Contraction during Progression from MDS to Secondary AML

Molecular Profiling of Decitabine Response in MDS and AML Patients

Comparison of Deep Whole Exome Versus Targeted Gene Sequencing for Assessment of Persistent Molecular Disease in Acute Myeloid Leukemia Samples

Gata2 Expression and Function in PML-RARA- driven Preleukemia and APL

DNMT3A R882 Alters the Epigenome of Hematopoietic Cells

The Molecular Basis of Long First Remissions in Normal Karyotype AML Patients

Whole Genome Bisulfite Sequencing of 63 Primary AML Samples Identifies a Unique DNA Hypermethylation Signature for Mutant IDH1/2 Cases That Is Different from That of TET2 Mutant AML

Evidence for Complete Mutation Clearance in Normal Karyotype AML Patients with Very Long (> 5 years) Remissions after Chemotherapy Alone

Improving Risk Assessment of AML with a Precision Genomic Strategy to Assess Mutation Clearance

Direct Detection of Expressed Mutations in AML Cells Using Single Cell RNA-Sequencing, and Its Impact on Defining Sources of Expression Heterogeneity

Generation and Characterization of Murine Allogeneic T Cell Resistant APL Cells

Clonal Evolution and Relapse in Adult De Novo Acute Myeloid Leukemia

Ultra-Deep Sequencing As a Predictive Tool for MDS Progression after Allogeneic Hematopoietic Cell Transplant

Clonal Evolution of Acute Myeloid Leukemia Following Allogeneic Stem Cell Transplantation

DNMT3A -Dependent DNA Methylation May Act As a Tumor Suppressor-Not a Tumor Promoter-during AML Progression

Dynamic Changes in MDS Clonal Architecture Following Allogeneic Stem Cell Transplant

Obesity As a Risk Factor for Acute Promyelocytic Leukemia. Results from Population and Case-Control Studies Across Western Countries and Correlation with Gene Expression in the TCGA

MIR142 Loss-of-Function Mutations Promote Leukemogenesis through Derepression of ASH1L Resulting in Increased HOX Gene Expression

Reprogramming of Leukemic and Pre-Leukemic Cells from Primary Human De Novo Acute Myeloid Leukemia Samples into Induced Pluripotent Stem (iPS) Cells

Loss-of-Function Mutations of MIR142 May Contribute to Leukemogenesis By Expanding the Pool of Myeloid-Biased HSCs

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American Society of Hematology

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ASH Publications

American Society of Hematology

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