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Journal Articles

Pioneer Part 2: A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study to Evaluate Safety and Efficacy of Avapritinib in Indolent Systemic Mastocytosis

Blood (2020) 136 (Supplement 1): 41–42.

https://doi.org/10.1182/blood-2020-136632

Published: 2020

Journal Articles

Increased Detection of KIT D816V Mutation in Peripheral Blood Samples from Patients with Indolent Systemic Mastocytosis (ISM) in the Phase 2 Pioneer Study Using a High Sensitivity Droplet Digital (dd) PCR Assay Compared with Next Generation Sequencing (NGS)

Tracy I. George, MD, Gerard Hoehn, PhD, Hui-Min Lin, PhD, Stephen Miller, PhD, Cem Akin, MDPhD

Blood (2020) 136 (Supplement 1): 7–8.

https://doi.org/10.1182/blood-2020-136930

Published: 2020

Journal Articles

Pure Pathologic Response Is Associated with Improved Overall Survival in Patients with Advanced Systemic Mastocytosis Receiving Avapritinib in the Phase I EXPLORER Study

Jason Gotlib, MD MS, Deepti H. Radia, MRCPI, FRCPath, Tracy I. George, MD, William A Robinson, MD PhD, Albert T. Quiery, MD, Mark W. Drummond, PhD FRCPath, Prithviraj Bose, MD, Elizabeth O. Hexner, MD, Elliott F. Winton, MD, Hans-Peter Horny, Prof, Dr, Meera Tugnait, PhD, Oleg Schmidt-Kittler, PhD, Erica K. Evans, PhD, Hui-Min Lin, PhD, Brenton G. Mar, MD PhD, Michael W. Deininger, MD PhD, Daniel J. DeAngelo, MD PhD

Blood (2020) 136 (Supplement 1): 37–38.

https://doi.org/10.1182/blood-2020-137413

Published: 2020

Journal Articles

Diagnostic Testing Patterns and Concordance with World Health Organization (WHO) Criteria for Patients (Pts) with Newly Diagnosed (ND) Myelodysplastic Syndromes (MDS) in the Connect ® MDS/AML Registry

Tracy I. George, MD, Christopher R. Cogle, MD, Guillermo Garcia-Manero, MD, David L. Grinblatt, Rami Komrokji, Michael R. Savona, MD, Bart L. Scott, MD, Mikkael A. Sekeres, MD MS, David P. Steensma, MD, E. Dawn Flick, Pavel Kiselev, Chrystal U. Louis, Melissa Nifenecker, Arlene S. Swern, Kathryn Foucar

Blood (2019) 134 (Supplement_1): 4747.

https://doi.org/10.1182/blood-2019-122913

Published: 2019

Journal Articles

Pioneer: A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of Avapritinib in Patients with Indolent or Smoldering Systemic Mastocytosis with Symptoms Inadequately Controlled with Standard Therapy

Blood (2019) 134 (Supplement_1): 2950.

https://doi.org/10.1182/blood-2019-126035

Published: 2019

Journal Articles

Comprehensive Cytokine Profiling of Patients with Advanced Systemic Mastocytosis Treated with Midostaurin

Asiri Ediriwickrema, MD, Daniel J. DeAngelo, MD, Tracy I. George, MD, Yael Rosenberg-Hasson, Cecelia Perkins, Cheryl Langford, Jason R. Gotlib, MDMS

Blood (2018) 132 (Supplement 1): 1792.

https://doi.org/10.1182/blood-2018-99-117689

Published: 2018

Journal Articles

Systemic Mastocytosis Patient Experience from Mast Cell Connect, the First Patient-Reported Registry for Mastocytosis

Philina Lee, PhD, Tracy I. George, MD, Hongliang Shi, MS, Erica K. Evans, PhD, Teghpal Singh, PhD, Anthony L Boral, MD PhD, Vanessa Rangel Miller, MS, MBA, Srdan Verstovsek, MD PhD

Blood (2016) 128 (22): 4783.

https://doi.org/10.1182/blood.V128.22.4783.4783

Published: 2016

Journal Articles

Current Diagnosis Patterns for Acute Myeloid Leukemia (AML) in Clinical Practice Compared with World Health Organization (WHO) 2008 Recommendations: Outcomes from the CONNECT ® Myelodysplastic Syndromes (MDS) and AML Disease Registry

Blood (2016) 128 (22): 3548.

https://doi.org/10.1182/blood.V128.22.3548.3548

Published: 2016

Journal Articles

A Recombinant Antibody to Siglec-8 Shows Selective ADCC Activity Against Mast Cells from Systemic Mastocytosis Patients

Rustom Falahati, PhD, Jessica Bright, Alejandro Dorenbaum, MD, Christopher Bebbington, PhD, Nenad Tomasevic, PhD, Diane Lidke, PhD, Tracy I. George, MD, Jason Gotlib, MD

Blood (2015) 126 (23): 4092.

https://doi.org/10.1182/blood.V126.23.4092.4092

Published: 2015

Journal Articles

Midostaurin (PKC412) Demonstrates a High Rate of Durable Responses in Patients with Advanced Systemic Mastocytosis: Results from the Fully Accrued Global Phase 2 CPKC412D2201 Trial

Jason Gotlib, MD MS, Hanneke C. Kluin-Nelemans, MD PhD, Tracy I. George, MD, Cem Akin, MD PhD, Karl Sotlar, MD, Olivier Hermine, MD PhD, Farrukh Awan, MD MS, Elizabeth O Hexner, MD, Michael Mauro, MD, David Sternberg, MD PhD, Matthieu Villeneuve, Fabienne Emery-Salbert, MSc, Eric Stanek, PharmD, Karin Hartmann, MD, Hans-Peter Horny, MD, Peter Valent, MD, Andreas Reiter, MD

Blood (2014) 124 (21): 636.

https://doi.org/10.1182/blood.V124.21.636.636

Published: 2014

Journal Articles

Durable Responses and Improved Quality Of Life With Midostaurin (PKC412) In Advanced Systemic Mastocytosis (SM): Updated Stage 1 Results Of The Global D2201 Trial

Jason Gotlib, MD, Hanneke C. Kluin-Nelemans, MD, PhD, Tracy I. George, MD, Cem Akin, MD, PhD, Karl Sotlar, MD, Olivier Hermine, Farrukh Awan, MD, MS, Elizabeth Hexner, MD, Michael Mauro, MD, Rodica Morariu, MD, Margaret Squier, MD, PhD, Matthieu Villeneuve, Fabienne Emery-Salbert, MSc, John Coombs, PharmD, MBA, Karin Hartmann, MD, Hans-Peter Horny, MD, Peter Valent, MD, Andreas Reiter, MD

Blood (2013) 122 (21): 106.

https://doi.org/10.1182/blood.V122.21.106.106

Published: 2013

Journal Articles

Refractory Anemia With Excess Blasts In Transformation (Acute Myeloid Leukemia with 20-29% Blasts) in Older Adults is Less Aggressive Than Acute Myeloid Leukemia With ≥30% Blasts

Blood (2013) 122 (21): 1345.

https://doi.org/10.1182/blood.V122.21.1345.1345

Published: 2013

Journal Articles

Hemoglobinuria and Mechanical Hemolysis Associated with Red Blood Cell Transfusion in Pediatric Patients

Janet McNaughton, MD, Jonathan Hughes, MD, Jennifer C. Andrews, MD, MSc, Tracy I. George, MD, Cassandra Bergero, RN, MSN, CNS, FNP, Kimberly Pike-Grimm, RN, MN, CNS, Susan Galel, MD, Chris Gonzalez, MD, Lawrence Goodnough, MD, Magali J. Fontaine, MD, PhD

Blood (2012) 120 (21): 3429.

https://doi.org/10.1182/blood.V120.21.3429.3429

Published: 2012

Journal Articles

KIT Inhibitor Midostaurin in Patients with Advanced Systemic Mastocytosis: Results of a Planned Interim Analysis of the Global CPKC412D2201 Trial

Jason Gotlib, MD, MS, Hanneke C. Kluin-Nelemans, MD, PhD, Tracy I. George, MD, Cem Akin, MD, PhD, Karl Sotlar, MD, Olivier Hermine, MD, PhD, Farrukh Awan, MD, MS, Elizabeth Hexner, MD, Michael J. Mauro, MD, Rodica Morariu, MD, Margaret Squier, MD, PhD, Matthieu Villeneuve, Fabienne Emery-Salbert, MSc, Karin Hartmann, MD, Hans-Peter Horny, MD, Peter Valent, MD, Andreas Reiter, MD

Blood (2012) 120 (21): 799.

https://doi.org/10.1182/blood.V120.21.799.799

Published: 2012

Journal Articles

AL Amyloidosis and Concomitant Myeloma: Time to Reconsider Assumptions

Wesley Witteles, MD, Ronald Witteles, MD, Michaela Liedtke, MD, Sally Arai, MD, Richard Lafayette, MD, Tracy I. George, MD, Stanley L. Schrier, MD

Blood (2010) 116 (21): 4044.

https://doi.org/10.1182/blood.V116.21.4044.4044

Published: 2010

Journal Articles

High Risk of Early Mortality in Adult Patients with Acquired Hemophagocytic Lymphohistiocytosis.

Aaron C. Logan, MD, PhD, Robert Su, MD, Tracy I. George, MD, Holbrook E. Kohrt, MD, Bruno C. Medeiros, MD, Ash A. Alizadeh, MD, PhD

Blood (2009) 114 (22): 1359.

https://doi.org/10.1182/blood.V114.22.1359.1359

Published: 2009

Journal Articles

Allosensitized Memory CD4 T Cells Induce Chronic Graft Versus Host Disease.

Suparna Dutt, PhD, Diane Tseng, BS, Tracy I. George, MD, Joerg Ermann, MD, Yinping Liu, MS, C. Garrison Fathman, MD, Samuel Strober, MD

Blood (2006) 108 (11): 449.

https://doi.org/10.1182/blood.V108.11.449.449

Published: 2006

Journal Articles

Memory CD4 T Cells Induce Graft Versus Host Disease.

Suparna Dutt, PhD, Diane Tseng, Joerg Ermann, MD, Yin Ping Liu, MD, Tracy I. George, MD, C. Garrison Fathman, MD, Samuel Strober, MD

Blood (2005) 106 (11): 1309.

https://doi.org/10.1182/blood.V106.11.1309.1309

Published: 2005

Journal Articles

TNFRSF6 (Fas Antigen) Mutations in Patients with Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman Disease).

Tracy I. George, MD, Lisa Ma, Peter L. Nagy, MD, PhD, Yasodha Natkunam, MD, PhD, Roger A. Warnke, MD, Ronald F. Dorfman, MD, Daniel A. Arber, MD

Blood (2004) 104 (11): 2389.

https://doi.org/10.1182/blood.V104.11.2389.2389

Published: 2004

NARROW

Pioneer Part 2: A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study to Evaluate Safety and Efficacy of Avapritinib in Indolent Systemic Mastocytosis

Increased Detection of KIT D816V Mutation in Peripheral Blood Samples from Patients with Indolent Systemic Mastocytosis (ISM) in the Phase 2 Pioneer Study Using a High Sensitivity Droplet Digital (dd) PCR Assay Compared with Next Generation Sequencing (NGS)

Pure Pathologic Response Is Associated with Improved Overall Survival in Patients with Advanced Systemic Mastocytosis Receiving Avapritinib in the Phase I EXPLORER Study

Diagnostic Testing Patterns and Concordance with World Health Organization (WHO) Criteria for Patients (Pts) with Newly Diagnosed (ND) Myelodysplastic Syndromes (MDS) in the Connect ® MDS/AML Registry

Pioneer: A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of Avapritinib in Patients with Indolent or Smoldering Systemic Mastocytosis with Symptoms Inadequately Controlled with Standard Therapy

Comprehensive Cytokine Profiling of Patients with Advanced Systemic Mastocytosis Treated with Midostaurin

Systemic Mastocytosis Patient Experience from Mast Cell Connect, the First Patient-Reported Registry for Mastocytosis

Current Diagnosis Patterns for Acute Myeloid Leukemia (AML) in Clinical Practice Compared with World Health Organization (WHO) 2008 Recommendations: Outcomes from the CONNECT ® Myelodysplastic Syndromes (MDS) and AML Disease Registry

A Recombinant Antibody to Siglec-8 Shows Selective ADCC Activity Against Mast Cells from Systemic Mastocytosis Patients

Midostaurin (PKC412) Demonstrates a High Rate of Durable Responses in Patients with Advanced Systemic Mastocytosis: Results from the Fully Accrued Global Phase 2 CPKC412D2201 Trial

Durable Responses and Improved Quality Of Life With Midostaurin (PKC412) In Advanced Systemic Mastocytosis (SM): Updated Stage 1 Results Of The Global D2201 Trial

Refractory Anemia With Excess Blasts In Transformation (Acute Myeloid Leukemia with 20-29% Blasts) in Older Adults is Less Aggressive Than Acute Myeloid Leukemia With ≥30% Blasts

Hemoglobinuria and Mechanical Hemolysis Associated with Red Blood Cell Transfusion in Pediatric Patients

KIT Inhibitor Midostaurin in Patients with Advanced Systemic Mastocytosis: Results of a Planned Interim Analysis of the Global CPKC412D2201 Trial

AL Amyloidosis and Concomitant Myeloma: Time to Reconsider Assumptions

High Risk of Early Mortality in Adult Patients with Acquired Hemophagocytic Lymphohistiocytosis.

Allosensitized Memory CD4 T Cells Induce Chronic Graft Versus Host Disease.

Memory CD4 T Cells Induce Graft Versus Host Disease.

TNFRSF6 (Fas Antigen) Mutations in Patients with Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman Disease).

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American Society of Hematology

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ASH Publications

American Society of Hematology

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