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Ute Modlich, DVM, PhD
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Journal Articles

Hematopoietic Stem Cell Gene Therapy For Wiskott- Aldrich Syndrome

Maximilian GW Witzel, MD, Christian J. Braun, MD, Kaan Boztug, MD, Anna Paruzynski, PhD, Michael H. Albert, MD, Adrian Schwarzer, MD PhD, Ute Modlich, DVM, PhD, Rita Beier, MD, Gudrun Göhring, MD, Sonja Naundorf, Klaus Kühlcke, Martina Rose, MD, Christopher Fraser, MD, Liesl Mathias, MD, Rudolf Ferrari, MD, Miguel R. Abboud, MD, MHA, Waleed Al-Herz, MD, Irina Kondratenko, MD, László Maródi, MD, Brigitte Schlegelberger, MD, PhD, Christopher Baum, MD, Manfred Schmidt, PhD, Christof von Kalle, MD, Christoph Klein, MD PhD
Journal: Blood
Blood (2013) 122 (21): 718.
https://doi.org/10.1182/blood.V122.21.718.718
Published: 2013
Journal Articles

Mutated IDH1 Has 2-Hydroxyglutarate-Independent Functions in Leukemogenesis

Anuhar Chaturvedi, PhD, Michelle Maria Araujo Cruz, Nidhi Jyotsana, Amit Sharma, Haiyang Yun, Kerstin Görlich, Martin Wichmann, Adrian Schwarzer, MD, Matthias Preller, PhD, Felicitas Thol, MD, Johann Meyer, PhD, Reinhard Haemmerle, Eduard A. Struys, PhD, Erwin E. Jansen, Ute Modlich, DVM, PhD, Zhixiong Li, MD, Laura M. Sly, PhD, Robert Geffers, PhD, Robert Lindner, PhD, Dietmar J. Manstein, PhD, Urlich Lehmann, PhD, Jürgen Krauter, MD, Arnold Ganser, Michael Heuser, MD
Journal: Blood
Blood (2012) 120 (21): 770.
https://doi.org/10.1182/blood.V120.21.770.770
Published: 2012
Journal Articles

Telomere Attrition and Chromosomal Instability During Long-Term Cultivation of Hematopoietic Stem Cells,

Kathrin Lange, Dipl. Biochem., Beate Kuhlmann, PhD, Andrea Schienke, Axel Schambach, MD PhD, Ute Modlich, DVM, PhD, Christopher Baum, MD, Brigitte Schlegelberger, M.D., Gudrun Göhring, MD
Journal: Blood
Blood (2011) 118 (21): 4001.
https://doi.org/10.1182/blood.V118.21.4001.4001
Published: 2011
Journal Articles

Lentiviral Vector Induced Insertional Haploinsufficiency of Ebf1 Causes Leukemia in a Murine Bone Marrow Transplantation Model

Dirk Heckl, PhD, Adrian Schwarzer, MD, Reinhard Haemmerle, Johann Meyer, PhD, Doris Steinemann, PhD, Cornelia Rudolph, PhD, Britta Skawran, PhD, Brigitte Schlegelberger, MD, Christopher Baum, MD, Ute Modlich, DVM, PhD
Journal: Blood
Blood (2011) 118 (21): 671.
https://doi.org/10.1182/blood.V118.21.671.671
Published: 2011
Journal Articles

Retroviral Ectopic Expression of a Signaling-Defective Thrombopoietin Receptor (Mpl) Induces a Systemic Loss of Hematopoietic Stem Cells in Mice,

Sabine Wintterle, MD, Dirk Heckl, PhD, Adrian Schwarzer, MD, Guntram Buesche, MD, Christopher Baum, MD, Ute Modlich, DVM, PhD
Journal: Blood
Blood (2011) 118 (21): 4175.
https://doi.org/10.1182/blood.V118.21.4175.4175
Published: 2011
Journal Articles

Use of the in Vitro Immortalization Assay to Quantify the Impact of Integration Spectrum and Vector Design on Insertional Mutagenesis

Ute Modlich, DVM, PhD, Julia Sürth, Daniela Zychlinski, PhD, Johann Meyer, PhD, Christian Brendel, Manuel Grez, PhD, Paritha Arumugam, PhD, Punam Malik, MD, Elke Grassman, PhD, Axel Schambach, MD PhD, Christopher Baum, MD
Journal: Blood
Blood (2011) 118 (21): 3123.
https://doi.org/10.1182/blood.V118.21.3123.3123
Published: 2011
Journal Articles

Somatic Gene Therapy for X-Linked Severe Combined Immunodeficiency Using a Self-Inactivating Modified Gammaretroviral Vector Results in An Improved Preclinical Safety Profile and Early Clinical Efficacy in a Human Patient

Sung-Yun Pai, MD, Luigi Daniele Notarangelo, MD, Chad Harris, Federica Cattaneo, MD, Matthew Wladkowski, Myriam Armant, PhD, Grace S. Kao, MD, Matthew Wielgosz, Arthur W. Nienhuis, MD, Ute Modlich, DVM, PhD, Martijn Brugman, PhD, Axel Schambach, MD PhD, Michael Rothe, Susannah I Thornhill, PhD, H. Bobby Gaspar, Kathryn Parsley, PhD, Samantha Cooray, PhD, Elke Grassman, Ph.D., Frederic Bushman, PhD, Sally Shupien, Matias Oleastro, MD, Salima Hacein-Bey-Abina, Alain Fischer, MD, Marina Cavazzana-Calvo, MD, PhD, Punam Malik, MD, Alexandra Filipovich, MD, Donald B. Kohn, MD, Christopher Baum, MD, David A. Williams, MD, Adrian J Thrasher, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 164.
https://doi.org/10.1182/blood.V118.21.164.164
Published: 2011
Journal Articles

Efficacy of Gene Therapy for Wiskott-Aldrich-Syndrome

Christian J. Braun, MD, Kaan Boztug, MD, Manfred Schmidt, PhD, Michael H Albert, MD, Adrian Schwarzer, MD, Anna Paruzynski, PhD, Ute Modlich, DVM, PhD, Rita Beier, MD, Gudrun Göhring, MD, Sonja Naundorf, Klaus Kühlcke, Martina Rose, MD, Christopher Fraser, MD, Liesl A. Mathias, MBBS, MD, Rudolf Ferrari, MD, Miguel R. Abboud, MD, Waleed Al-Herz, MD, Irina Kondratenko, MD, László Maródi, MD, Brigitte Schlegelberger, M.D., Christopher Baum, MD, Christof von Kalle, MD, PhD, Christoph Klein, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 165.
https://doi.org/10.1182/blood.V118.21.165.165
Published: 2011