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Nidhi Jyotsana
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Journal Articles

Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in AML

Sagarajit Mohanty, MSc, Nidhi Jyotsana, PhD, Amit Sharma, PhD, Basem Othman, Arnold Kloos, PhD, Madhvi Mandhania, MSc, Renate Schottmann, Euan Ramsay, PhD, Hans- Peter Vornlocher, PhD, Arnold Ganser, MD, Felicitas Thol, MD, Michael Heuser, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2545.
https://doi.org/10.1182/blood-2019-123709
Published: 2019
Journal Articles

Signaling Pathways of Mutant IDH1 Independent of R-2-Hydroxyglutarate

Charu Gupta, Michelle Maria Araujo Cruz, PhD, Nidhi Jyotsana, PhD, Amit Sharma, PhD, Ramya Goparaju, PhD, Kerstin Görlich, Renate Schottmann, Eduard Struys, PhD, Erwin E Jansen, Felicitas Thol, MD, Arnold Ganser, MD, Michael Heuser, MD, Anuhar Chaturvedi, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2617.
https://doi.org/10.1182/blood-2018-99-110159
Published: 2018
Journal Articles

Serially Transplantable Patient-Derived Xenograft Model of Chronic Myelomonocytic Leukemia (CMML)

Arnold Kloos, PhD, Felicitas Thol, MD, Lina Winckler, Razif Gabdoulline, PhD, Konstantinos Mintzas, Nidhi Jyotsana, PhD, Renate Schottmann, Felix F. Adams, Adrian Schwarzer, MD PhD, Dirk Heckl, PhD, Suzan Imren, MD, R. Keith Humphries, Arnold Ganser, MD, Michael Heuser, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4236.
https://doi.org/10.1182/blood.V130.Suppl_1.4236.4236
Published: 2017
Journal Articles

Effective Treatment of Human CML By RNAi In Vivo in a Xenotransplantation Mouse Model

Nidhi Jyotsana, PhD, Amit Sharma, PhD MSc, BSc, Anuhar Chaturvedi, PhD MS, BPharm, Colin Walsh, Anitha Thomas, Michaela Scherr, PhD, Matthias Eder, MD, Karin Battmer, Florian Kuchenbauer, MD PhD, Sajti Laszlo, Annette Barchanski, Kerstin Goerlich, Robert Lindner, Fatih Noyan, PhD, Suehs.Kurt Wolfram, Denis Grote-Koska, Korbinian Brand, Hans-Peter Vornlocher, Arnold Ganser, MD, Euan Ramsay, Pieter Cullis, Michael Heuser, MD
Journal: Blood
Blood (2015) 126 (23): 1261.
https://doi.org/10.1182/blood.V126.23.1261.1261
Published: 2015
Journal Articles

A Novel Inhibitor of Mutant IDH1 Induces Differentiation in Vivo and Prolongs Survival in a Mouse Model of Leukemia

Anuhar Chaturvedi, PhD, Michelle Maria Araujo Cruz, Ramya Goparaju, Nidhi Jyotsana, Heike Baehre, PhD, Kerstin Goerlich, Renate Schottmann, Matthias Preller, PhD, Eduard A. Struys, PhD, Arnold Kloos, PhD, Volkhard Kaever, PhD, Arnold Ganser, Felicitas Thol, MD, Michael Heuser, MD
Journal: Blood
Blood (2014) 124 (21): 3598.
https://doi.org/10.1182/blood.V124.21.3598.3598
Published: 2014
Journal Articles

The Metabolite R-2-Hydroxyglutarate (R2HG) Collaborates with HoxA9 to Induce Monocytic Leukemia

Anuhar Chaturvedi, PhD, Michelle Maria Araujo Cruz, Nidhi Jyotsana, Amit Sharma, PhD, Ramya Goparaju, Vishwas Sharma, PhD, Adrian Schwarzer, MDPhD, Kerstin Goerlich, Renate Schottmann, Eduard A. Struys, PhD, Erwin E. Jansen, Robert Geffers, PhD, Gudrun Goehring, MD, Felicitas Thol, MD, Arnold Ganser, Michael Heuser, MD
Journal: Blood
Blood (2014) 124 (21): 366.
https://doi.org/10.1182/blood.V124.21.366.366
Published: 2014
Journal Articles

High-Throughput Drug Screening Identifies Pyrimethamine As a Potent and Selective Inhibitor of Acute Myeloid Leukemia

Amit Sharma, PhD, Nidhi Jyotsana, Courteney K. Lai, BSc, Anuhar Chaturvedi, PhD, Kerstin Görlich, Cecilia Murphy, Jan E. Blanchard, Arnold Ganser, Eric Brown, John A. Hassell, R. Keith Humphries, MD PhD, Michael A Morgan, PhD, Michael Heuser, MD
Journal: Blood
Blood (2014) 124 (21): 2304.
https://doi.org/10.1182/blood.V124.21.2304.2304
Published: 2014
Journal Articles

Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML

Anuhar Chaturvedi, Michelle Maria Araujo Cruz, Nidhi Jyotsana, Amit Sharma, Haiyang Yun, Kerstin Görlich, Martin Wichmann, Adrian Schwarzer, Matthias Preller, Felicitas Thol, Johann Meyer, Reinhard Haemmerle, Eduard A. Struys, Erwin E. Jansen, Ute Modlich, Zhixiong Li, Laura M. Sly, Robert Geffers, Robert Lindner, Dietmar J. Manstein, Ulrich Lehmann, Jürgen Krauter, Arnold Ganser, Michael Heuser
Journal: Blood
Blood (2013) 122 (16): 2877–2887.
https://doi.org/10.1182/blood-2013-03-491571
Published: 2013
Includes: Supplemental data
Journal Articles

Mutated IDH1 Has 2-Hydroxyglutarate-Independent Functions in Leukemogenesis

Anuhar Chaturvedi, PhD, Michelle Maria Araujo Cruz, Nidhi Jyotsana, Amit Sharma, Haiyang Yun, Kerstin Görlich, Martin Wichmann, Adrian Schwarzer, MD, Matthias Preller, PhD, Felicitas Thol, MD, Johann Meyer, PhD, Reinhard Haemmerle, Eduard A. Struys, PhD, Erwin E. Jansen, Ute Modlich, DVM, PhD, Zhixiong Li, MD, Laura M. Sly, PhD, Robert Geffers, PhD, Robert Lindner, PhD, Dietmar J. Manstein, PhD, Urlich Lehmann, PhD, Jürgen Krauter, MD, Arnold Ganser, Michael Heuser, MD
Journal: Blood
Blood (2012) 120 (21): 770.
https://doi.org/10.1182/blood.V120.21.770.770
Published: 2012