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Renate Schottmann
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Journal Articles

Efficacy of Chemotherapy, Phd-Inhibitor Molidustat or BRD4 Inhibitor JQ1 in Combination with Targeted Inhibition of Mutated IDH1 in Human AML In Vivo

Anuhar Chaturvedi, PhD, Charu Gupta, Stefan Kaulfuss, PhD, Basem Othman, Kerstin Görlich, Renate Schottmann, Olaf Panknin, Markus Wagner, PhD, Arnold Ganser, MD, Michael Jeffers, PhD, Andrea Haegebarth, Michael Heuser, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3933.
https://doi.org/10.1182/blood-2019-124016
Published: 2019
Journal Articles

Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in AML

Sagarajit Mohanty, MSc, Nidhi Jyotsana, PhD, Amit Sharma, PhD, Basem Othman, Arnold Kloos, PhD, Madhvi Mandhania, MSc, Renate Schottmann, Euan Ramsay, PhD, Hans- Peter Vornlocher, PhD, Arnold Ganser, MD, Felicitas Thol, MD, Michael Heuser, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2545.
https://doi.org/10.1182/blood-2019-123709
Published: 2019
Journal Articles

Functional Screening for Pathways Regulating Chemoresistance and Sensitivity in Leukemia Stem Cells

Konstantinos Mintzas, MSc, Arnold Kloos, Razif Gabdoulline, Renate Schottmann, Simon Danisch, PhD, Renata Stripecke, Prof., Arnold Ganser, MD, Felicitas Thol, MD, Michael Heuser, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3933.
https://doi.org/10.1182/blood-2018-99-112373
Published: 2018
Journal Articles

Prolyl Hydroxylase 3 (Phd3) Is a Therapeutic Target in Isocitrate Dehydrogenase 1 (IDH1) Mutated Acute Myeloid Leukemia

Anuhar Chaturvedi, PhD, Michelle Maria Araujo Cruz, PhD, Ramya Goparaju, PhD, Razif Gabdoulline, Renate Schottmann, Kerstin Görlich, Arnold Kloos, Felicitas Thol, MD, Robert Geffers, PhD, Dimitrios Mougiakakos, Peter Carmeliet, MD PhD, Arnold Ganser, MD, Michael Heuser, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 759.
https://doi.org/10.1182/blood-2018-99-110425
Published: 2018
Journal Articles

Signaling Pathways of Mutant IDH1 Independent of R-2-Hydroxyglutarate

Charu Gupta, Michelle Maria Araujo Cruz, PhD, Nidhi Jyotsana, PhD, Amit Sharma, PhD, Ramya Goparaju, PhD, Kerstin Görlich, Renate Schottmann, Eduard Struys, PhD, Erwin E Jansen, Felicitas Thol, MD, Arnold Ganser, MD, Michael Heuser, MD, Anuhar Chaturvedi, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2617.
https://doi.org/10.1182/blood-2018-99-110159
Published: 2018
Journal Articles

Synergistic Activity of IDH1 Inhibitor Bay-1436032 with Azacitidine in IDH1 Mutant Acute Myeloid Leukemia

Anuhar Chaturvedi, PhD, Charu Gupta, Ramya Goparaju, Razif Gabdoulline, PhD, Stefan Kaulfuss, PhD, Kerstin Görlich, Renate Schottmann, Olaf Panknin, Markus Wagner, PhD, Robert Geffers, PhD, Arnold Ganser, MD, Felicitas Thol, MD, Michael Jeffers, PhD, Andrea Haegebarth, Michael Heuser, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1352.
https://doi.org/10.1182/blood.V130.Suppl_1.1352.1352
Published: 2017
Journal Articles

Serially Transplantable Patient-Derived Xenograft Model of Chronic Myelomonocytic Leukemia (CMML)

Arnold Kloos, PhD, Felicitas Thol, MD, Lina Winckler, Razif Gabdoulline, PhD, Konstantinos Mintzas, Nidhi Jyotsana, PhD, Renate Schottmann, Felix F. Adams, Adrian Schwarzer, MD PhD, Dirk Heckl, PhD, Suzan Imren, MD, R. Keith Humphries, Arnold Ganser, MD, Michael Heuser, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4236.
https://doi.org/10.1182/blood.V130.Suppl_1.4236.4236
Published: 2017
Journal Articles

Patient Derived Xenotransplantation Model of Atypical Chronic Myeloid Leukemia (aCML)

Arnold Kloos, PhD, Felicitas Thol, MD, Sabrina Klesse, Alessandro Liebich, Arne Trummer, MD, Renate Schottmann, Rubén Trespando Jiménez, Gudrun Göhring, MD, Brigitte Schlegelberger, MD PhD, Arnold Ganser, MD, Michael Heuser, MD
Journal: Blood
Blood (2015) 126 (23): 2836.
https://doi.org/10.1182/blood.V126.23.2836.2836
Published: 2015
Journal Articles

A Novel Inhibitor of Mutant IDH1 Induces Differentiation in Vivo and Prolongs Survival in a Mouse Model of Leukemia

Anuhar Chaturvedi, PhD, Michelle Maria Araujo Cruz, Ramya Goparaju, Nidhi Jyotsana, Heike Baehre, PhD, Kerstin Goerlich, Renate Schottmann, Matthias Preller, PhD, Eduard A. Struys, PhD, Arnold Kloos, PhD, Volkhard Kaever, PhD, Arnold Ganser, Felicitas Thol, MD, Michael Heuser, MD
Journal: Blood
Blood (2014) 124 (21): 3598.
https://doi.org/10.1182/blood.V124.21.3598.3598
Published: 2014
Journal Articles

The Metabolite R-2-Hydroxyglutarate (R2HG) Collaborates with HoxA9 to Induce Monocytic Leukemia

Anuhar Chaturvedi, PhD, Michelle Maria Araujo Cruz, Nidhi Jyotsana, Amit Sharma, PhD, Ramya Goparaju, Vishwas Sharma, PhD, Adrian Schwarzer, MDPhD, Kerstin Goerlich, Renate Schottmann, Eduard A. Struys, PhD, Erwin E. Jansen, Robert Geffers, PhD, Gudrun Goehring, MD, Felicitas Thol, MD, Arnold Ganser, Michael Heuser, MD
Journal: Blood
Blood (2014) 124 (21): 366.
https://doi.org/10.1182/blood.V124.21.366.366
Published: 2014