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Vassilios I. Avramis
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Journal Articles

Is glutamine depletion needed in ALL disease?

Vassilios I. Avramis
Journal: Blood
Blood (2014) 123 (23): 3532–3533.
https://doi.org/10.1182/blood-2014-04-565523
Published: 2014
Journal Articles

High-Grade Pegylated Asparaginase-Related Hepatotoxicity Occurrence In a Pediatric-Inspired Adult Acute Lymphoblastic Leukemia Regimen Does Not Necessarily Predict Recurrent Hepatotoxicity In Subsequent Cycles

Patrick W. Burke, MD, Ibrahim Aldoss, MD, Matthew A. Lunning, DO, Vassilios I. Avramis, PhD, Ann M. Mohrbacher, MD, Vinod Pullarkat, MD, Martin S. Tallman, MD, Dan Douer, MD
Journal: Blood
Blood (2013) 122 (21): 2671.
https://doi.org/10.1182/blood.V122.21.2671.2671
Published: 2013
Journal Articles

Adverse Reactions to PEG and Erwinia Asparaginase and Correlation with Anti-Asparaginase Antibody Data and Survival in Children with Acute Lymphoblastic Leukemia (ALL): A Report From the Children's Oncology Group Study CCG 1961.

Girish Dhall, M.D., Tamekia Jones, PhD, David Radvinsky, Nathan Robison, MD, Anna Butturini, MD, Joan I Rubin, RN, Paul S. Gaynon, MD, Eduard H Panosyan, MD, Ioannis A Avramis, Vassilios I Avramis, PhD, Lawrence J. Ettinger, MD, Nita L. Seibel, MD
Journal: Blood
Blood (2009) 114 (22): 3077.
https://doi.org/10.1182/blood.V114.22.3077.3077
Published: 2009
Journal Articles

Obesity Alters the Pharmacokinetics of Vincristine in Mice.

James W Behan, Vassilios I Avramis, PhD, Jason P Yun, Anna Butturini, MD, Steven D Mittelman, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1636.
https://doi.org/10.1182/blood.V112.11.1636.1636
Published: 2008
Journal Articles

Sustained and Prolonged Asparagine Depletion by Multiple Doses of Intravenous Pegylated Asparaginase in the Treatment of Adults with Newly Diagnosed Acute Lymphoblastic Leukemia.

Dan Douer, Kristy Watkins, Lisa Mark, Mohrbacher Ann, Allen S Yang, Vassilios I Avramis
Journal: Blood
Blood (2008) 112 (11): 1928.
https://doi.org/10.1182/blood.V112.11.1928.1928
Published: 2008
Journal Articles

Failure of Asparagine (ASN) Depletion, Not Inadequate Asparaginase (ASNase) Activity, Predicts Relapse in Standard Risk (SR) Childhood Acute Lymphoblastic Leukemia (ALL): A Children’s Oncology Group (COG) Report.

Vassilios I. Avramis, PhD, John S. Holcenberg, MD, Alice G. Ettinger, RN, Linda C. Stork, MD, Mei La, MS, Paul S. Gaynon, MD
Journal: Blood
Blood (2007) 110 (11): 588.
https://doi.org/10.1182/blood.V110.11.588.588
Published: 2007
Journal Articles

Pharmacodynamics and safety of intravenous pegaspargase during remission induction in adults aged 55 years or younger with newly diagnosed acute lymphoblastic leukemia

Clinical Trials & Observations
Dan Douer, Henry Yampolsky, Lewis J. Cohen, Kristy Watkins, Alexandra M. Levine, Antonia P. Periclou, Vassilios I. Avramis
Journal: Blood
Blood (2006) 109 (7): 2744–2750.
https://doi.org/10.1182/blood-2006-07-035006
Published: 2006
Journal Articles

Assessment of Anti-Asparaginase (ASNase) Antibodies (Ab) and ASNase Activity after Suspected Clinical Allergy.

Prakash N. Tiwari, MD, Monica Zielinski, MS, John J. Quinn, MD, Stuart E. Siegel, MD, Paul S. Gaynon, MD, Peter Wakamatsu, MPH, Nita L. Seibel, MD, Vassilios I. Avramis, PhD
Journal: Blood
Blood (2006) 108 (11): 1878.
https://doi.org/10.1182/blood.V108.11.1878.1878
Published: 2006
Journal Articles

A Phase I Study of Oral 6-Thioguanine, Followed by Continuous Infusion Cytarabine, Followed by Intramuscular PEG-Asparaginase (“TGAP”) in Children with Relapsed or Refractory Acute Leukemia or Non-Hodgkin’s Lymphoma.

Cecilia H. Fu, MD, Janet L. Franklin, MD, Paul Gaynon, MD, Colleen McCarthy, RN, Edward Panosyan, MD, Stuart E. Siegel, MD, Vassilios I. Avramis, MD
Journal: Blood
Blood (2006) 108 (11): 4536.
https://doi.org/10.1182/blood.V108.11.4536.4536
Published: 2006
Journal Articles

Pharmacokinetics and Pharmacodynamics of Three Asparaginases in Pediatric Patients with Higher Risk Acute Lymphoblastic Leukemia: A Report from CCG-1961.

Eduard H. Panosyan, M.D., Nita L. Seibel, M.D., Rita S. Grigoryan, M.D., Ioannis A. Avramis, B.S., Jon D. Jaques, Lawrence J. Ettinger, M.D., Paul S. Gaynon, M.D., Harland N. Sather, Ph.D., Janet Franklin, M.D., Fu Cecilia, M.D., Stuart E. Siegel, M.D., Howard J. Fingert, M.D., Vassilios I. Avramis, Ph.D.
Journal: Blood
Blood (2004) 104 (11): 2745.
https://doi.org/10.1182/blood.V104.11.2745.2745
Published: 2004
Journal Articles

Pharmacodynamic (PD) Analyses of Asparagine (Asn) Deamination and Asn Input (Imax) in Serum of Pediatric Patients with Standard Risk Acute Lymphoblastic Leukemia (SR ALL) Receiving Native or Pegylated E. Coli Asparaginases (ASNase) (CCG-1962).

Vassilios I. Avramis, Ph.D., Eduard H. Panosyan, M.D., Cecilia H. Fu, M.D., Linda C. Stork, M.D., Paul S. Gaynon, M.D.
Journal: Blood
Blood (2004) 104 (11): 2082.
https://doi.org/10.1182/blood.V104.11.2082.2082
Published: 2004
Journal Articles

A randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: a Children's Cancer Group study

Clinical Trials & Observations
Vassilios I. Avramis, Susan Sencer, Antonia P. Periclou, Harland Sather, Bruce C. Bostrom, Lewis J. Cohen, Alice G. Ettinger, Lawrence J. Ettinger, Janet Franklin, Paul S. Gaynon, Joanne M. Hilden, Beverly Lange, Fataneh Majlessipour, Pracad Mathew, Michael Needle, Joseph Neglia, Gregory Reaman, John S. Holcenberg
Journal: Blood
Blood (2002) 99 (6): 1986–1994.
https://doi.org/10.1182/blood.V99.6.1986
Published: 2002