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Journal Articles

Iomab with Adoptive Cellular Therapy (Iomab-ACT): A Pilot Study of 131-I Apamistamab Followed By CD19-Targeted CAR T-Cell Therapy for Patients with Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia or Diffuse Large B-Cell Lymphoma

Mark B. Geyer, Briana Cadzin, Elizabeth Halton, Peter Kane, Brigitte Senechal, Eileen M. Geoghegan, Vijay Reddy, Mark S. Berger, Dale Ludwig, Neeta Pandit-Taskar, Craig S. Sauter
Journal: Blood
Blood (2021) 138 (Supplement 1): 4810.
https://doi.org/10.1182/blood-2021-144994
Published: 2021
Journal Articles

Clinical Experience in the Randomized Phase 3 Sierra Trial: Anti-CD45 Iodine ( 131 I) Apamistamab [Iomab-B] Conditioning Enables Hematopoietic Cell Transplantation with Successful Engraftment and Acceptable Safety in Patients with Active, Relapsed/Refractory AML Not Responding to Targeted Therapies

Boglarka Gyurkocza, Rajneesh Nath, Stuart Seropian, Hannah Choe, Mark R. Litzow, Nebu V. Koshy, Patrick Stiff, Camille Abboud, Sr., Benjamin Tomlinson, Sunil Abhyankar, Parameswaran Hari, Zaid S. Al-Kadhimi, George L. Chen, Mitchell Sabloff, Johnnie J. Orozco, James M. Foran, Partow Kebriaei, Katarzyna Joanna Jamieson, Margarida Magalhaes Magalhaes-Silverman, Koen van Besien, Michael W. Schuster, Arjun Law, Moshe Levy, Hillard M Lazarus, Sergio A Giralt, Mark S. Berger, Jennifer A Spross, Avinash G Desai, Vijay Reddy, John M. Pagel
Journal: Blood
Blood (2021) 138 (Supplement 1): 1791.
https://doi.org/10.1182/blood-2021-148497
Published: 2021
Journal Articles

Personalized Targeted Radioimmunotherapy with Anti-CD45 Iodine ( 131 I) Apamistamab [Iomab-B] in Patients with Active Relapsed or Refractory Acute Myeloid Leukemia Results in Successful Donor Hematopoietic Cells Engraftment with the Timing of Engraftment Not Related to the Radiation Dose Delivered

Boglarka Gyurkocza, MD, Rajneesh Nath, MD, Hannah Choe, MD, Stuart Seropian, MD, Patrick J. Stiff, MD, Sunil Abhyankar, MD, Edward Agura, MD, Mark Litzow, MD, Benjamin K. Tomlinson, MD, George L. Chen, MD, Parameswaran Hari, MD MRCP, Johnnie Orozco, MD, Zaid S. Al-Kadhimi, MD, Camille Abboud, MD, Koen Van Besien, MD PhD, Mitchell Sabloff, MSc,MDFRCPC, Margarida Magalhaes Magalhaes-Silverman, James M. Foran, MD, Michael W. Schuster, MD, Partow Kebriaei, MD, Moshe Y. Levy, MD, Hillard M Lazarus, MD, Sergio A. Giralt, MD, Qing Liang, PhD, Mark S. Berger, MD, Vijay Reddy, MDPhD, John M. Pagel, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42–44.
https://doi.org/10.1182/blood-2020-134948
Published: 2020
Journal Articles

High Doses of Targeted Radiation with Anti-CD45 Iodine ( 131 I) Apamistamab [Iomab-B] Do Not Correlate with Incidence of Mucositis, Febrile Neutropenia or Sepsis in the Prospective, Randomized Phase 3 Sierra Trial for Patients with Relapsed or Refractory Acute Myeloid Leukemia

Boglarka Gyurkocza, MD, Rajneesh Nath, MD, Hannah Choe, MD, Stuart Seropian, MD, Patrick J. Stiff, MD, Sunil Abhyankar, MD, Edward Agura, MD, Mark Litzow, MD, Benjamin K. Tomlinson, MD, George L. Chen, MD, Parameswaran Hari, MD MRCP, Johnnie Orozco, MD, Zaid S. Al-Kadhimi, MD, Camille Abboud, MD, Koen Van Besien, MD PhD, Mitchell Sabloff, MSc,MDFRCPC, Margarida Magalhaes Magalhaes-Silverman, James M. Foran, MD, Michael W. Schuster, MD, Partow Kebriaei, MD, Moshe Levy, MD, Hillard M Lazarus, MD, Sergio A. Giralt, MD, Qing Liang, PhD, Mark S. Berger, MD, Vijay Reddy, MDPhD, John M. Pagel, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30–31.
https://doi.org/10.1182/blood-2020-134624
Published: 2020
Journal Articles

Sierra Clinical Trial Dosimetry Results Support Low Dose Anti-CD45 Iodine (131I) Apamistamab [Iomab-B] for Targeted Lymphodepletion Prior to Adoptive Cell Therapy

Rajneesh Nath, MD, Eileen M Geoghegan, Matthew L. Ulrickson, MD, Jennifer A Spross, MA, Renee H Lichtenstein, BA, Sandy Konerth, MS, Darrell R. Fisher, PhD, Qing Liang, PhD, Dale Ludwig, PhD BS, Vijay Reddy, MD PhD, Mark S. Berger, MD, Boglarka Gyurkocza, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1958.
https://doi.org/10.1182/blood-2019-128838
Published: 2019
Journal Articles

Re-Induction and Targeted Conditioning with Anti-CD45 Iodine ( 131 I) Apamistamab [Iomab-B] Leads to High Rates of Transplantation and Successful Engraftment in Older Patients with Active, Relapsed or Refractory (rel/ref) AML after Failure of Chemotherapy and Targeted Agents: Preliminary Midpoint Results from the Prospective, Randomized Phase 3 Sierra Trial

Boglarka Gyurkocza, MD, Rajneesh Nath, MD, Patrick J. Stiff, MD, Edward Agura, MD, Mark Litzow, MD, Ben Tomlinson, MD, Hannah K. Choe, MD, Sunil Abhyankar, MD, Stuart Seropian, MD, George L. Chen, MD, Parameswaran Hari, MBBS, MD, Zaid S. Al-Kadhimi, MD, James M. Foran, MD, Johnnie Orozco, MD, Koen Van Besien, MD PhD, Mitchell Sabloff, MD, Partow Kebriaei, MD, Moshe Yair Levy, MD, Hillard M Lazarus, MD, Sergio A Giralt, MD, Mark S. Berger, MD, Vijay Reddy, MD PhD, John M. Pagel, MD PhD DSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 5642.
https://doi.org/10.1182/blood-2019-122776
Published: 2019
Journal Articles

Feasibility of Administering Anti-CD45 Iodine ( 131 I) Apamistamab [Iomab-B] for Re-Induction and Targeted Conditioning in Older Patients with Active, Relapsed or Refractory AML without Lead-Lined Rooms: Sierra Trial Experience at MSKCC

Bae P Chu, MPH, Neeta Pandit-Taskar, MD, Boglarka Gyurkocza, MD, Qing Liang, PhD, Daniel Miodownik, MPH, Vijay Reddy, MD PhD, Mark S. Berger, MD, Lawrence T. Dauer, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5839.
https://doi.org/10.1182/blood-2019-131230
Published: 2019
Journal Articles

Preclinical Development of an Actinium-225-Labeled Antibody Radio-Conjugate Directed Against CD45 for Targeted Conditioning and Radioimmunotherapy

Dale Ludwig, PhD BS, Ruth Bryan, Wojciech Dawicki, PhD, Eileen M Geoghegan, Qing Liang, PhD, Sandesh Seth, MS, MBA, Mamata Gokhale, Mark S. Berger, MD, Vijay Reddy, MD PhD, Ravendra Garg, Kevin Allen, PhD, Ekaterina Dadachova
Journal: Blood
Blood (2019) 134 (Supplement_1): 5601.
https://doi.org/10.1182/blood-2019-128678
Published: 2019
Journal Articles

Risk Model for Overall Survival for Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia: Validated for Patients on Ibrutinib, Idelalisib, Venetoclax, or Chemoimmunotherapy

Jacob D. Soumerai, MD, Ai Ni, PhD, Mohamed Darif, PhD, Anil Londhe, PhD, Guan Xing, PhD, Yong Mun, PhD, Neil E. Kay, MD, Tait D. Shanafelt, MD, Kari G. Chaffee, MS, Richard R. Furman, MD, Peter Hillmen, MB ChB, PhD FRCP, FRCPath, Jeff Sharman, MD, John F. Seymour, MBBS, PhD, Asher A. Chanan-Khan, MD, John C. Byrd, MD, Jeffrey A. Jones, MD MPH, Lucille A. Ferrante, MD, Lyndah K. Dreiling, MD, Mehrdad Mobasher, MD MPH, Thomas Stark, MD PhD, Vijay Reddy, MD PhD, Angela J. Howes, BSc, PhD, Danelle James, MD MAS, Pankaj Bhargava, MD, Andrew D. Zelenetz, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4394.
https://doi.org/10.1182/blood-2018-99-112989
Published: 2018
Journal Articles

Targeted Conditioning of Iomab-B ( 131 I-anti-CD45) Prior to Allogeneic Hematopoietic Cell Transplantation Versus Conventional Care in Relapsed or Refractory Acute Myeloid Leukemia (AML): Preliminary Feasibility and Safety Results from the Prospective, Randomized Phase 3 Sierra Trial

Edward Agura, MD, Boglarka Gyurkocza, MD, Rajneesh Nath, MD, Mark R. Litzow, MD, Benjamin K. Tomlinson, MD, Sunil Abhyankar, MD, Stuart Seropian, MD, Patrick J. Stiff, MD, Hannah K. Choe, MD, Partow Kebriaei, MD, James M. Foran, MD, George Chen, MD, Moshe Yair Levy, MD, Hillard M Lazarus, MD, Sergio Giralt, MD, Mark S. Berger, MD, Vijay Reddy, MD PhD, John M. Pagel, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1017.
https://doi.org/10.1182/blood-2018-99-111914
Published: 2018
Journal Articles

Incidence of and Risk Factors for Major Hemorrhage in Patients Treated with Ibrutinib: Results from an Integrated Analysis

Jennifer R. Brown, MD PhD, Javid Moslehi, MD, Michael S. Ewer, MD MPH, JD, Susan M. O'Brien, MD, Paolo Ghia, MD PhD, Florence Cymbalista, MD, Tait D. Shanafelt, MD, Graeme Fraser, MD, Simon Rule, MD, Steven E. Coutre, MD, Marie-Sarah Dilhuydy, MD, Paula Cramer, MD, Ulrich Jaeger, MD, Martin Dreyling, MD, John C. Byrd, MD, Steven Treon, MD PhD, Emily Liu, Stephen Chang, PhD, Amulya Bista, Rama Vempati, Lisa Boornazian, BSN, Rudolph Valentino, PharmD, Vijay Reddy, MD PhD, Michelle Mahler, MD, Huiying Yang, MD PhD, Jan A. Burger, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1743.
https://doi.org/10.1182/blood.V130.Suppl_1.1743.1743
Published: 2017
Journal Articles

A Validated Risk Model for Overall Survival in Relapsed/Refractory Chronic Lymphocytic Leukemia Applicable to Patients Treated with Novel Therapies and Standard of Care

Jacob D. Soumerai, MD, Ai Ni, PhD, Mohamed Darif, PhD, Anil Londhe, PhD, Guan Xing, PhD, Julie Huang, PhD, Ming Lin, PhD, John C. Byrd, MD, Asher A. Chanan-Khan, MD, Richard R. Furman, MD, Michael Hallek, MD, Peter Hillmen, MBChB, PhD, Jeffrey Jones, MD, Jeffrey P. Sharman, MD, Lucille Ferrante, MD, Vijay Reddy, MD PhD, Lyndah K. Dreiling, MD, Henry Adewoye, MD, Ronald Dubowy, MD, Angela Howes, PhD, Danelle F. James, MD MAS, Andrew D. Zelenetz, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4303.
https://doi.org/10.1182/blood.V130.Suppl_1.4303.4303
Published: 2017
Journal Articles

Safety Results from the United States Cohort of the Ibrutinib Early Access Treatment Protocol (EAP: MCL4001) in Patients with Relapsed or Refractory Mantle Cell Lymphoma

Peter Martin, MD, Andre Goy, MD, Radhakrishnan Ramchandren, MD, Lucille Ferrante, MD, Vijay Reddy, MD PhD, Anil Londhe, Mark Wildgust, Tracy McGowan, MD, Nancy L Bartlett, MD
Journal: Blood
Blood (2014) 124 (21): 4461.
https://doi.org/10.1182/blood.V124.21.4461.4461
Published: 2014
Journal Articles

Amino acid substitution at peptide-binding pockets of HLA class I molecules increases risk of severe acute GVHD and mortality

Joseph Pidala, Tao Wang, Michael Haagenson, Stephen R. Spellman, Medhat Askar, Minoo Battiwalla, Lee Ann Baxter-Lowe, Menachem Bitan, Marcelo Fernandez-Viña, Manish Gandhi, Ann A. Jakubowski, Martin Maiers, Susana R. Marino, Steven G. E. Marsh, Machteld Oudshoorn, Jeanne Palmer, Vinod K. Prasad, Vijay Reddy, Olle Ringden, Wael Saber, Stella Santarone, Kirk R. Schultz, Michelle Setterholm, Elizabeth Trachtenberg, E. Victoria Turner, Ann E. Woolfrey, Stephanie J. Lee, Claudio Anasetti
Journal: Blood
Blood (2013) 122 (22): 3651–3658.
https://doi.org/10.1182/blood-2013-05-501510
Published: 2013
Includes: Supplemental data
Journal Articles

Efficacy Of a Pharmacokinetics-Directed IV Busulfan (Bu), Plus Cyclophosphamide (Cy) and Etoposide (E) Preparative Regimen With Autologous Hematopoietic Stem Cell Transplantation For Lymphoma: Final Report Of a Multi-Center Phase 2 Study In North America

Christopher R. Flowers, MD, Michael Lill, M.D., Luciano J Costa, MD, PhD, Tsiporah B. Shore, William Vaughan, MD, Michael Craig, MD, Cesar O. Freytes, MD, Thomas C. Shea, M.D., Mitchell E. Horwitz, MD, Joseph W. Fay, MD, Shin Mineishi, MD, Damiano Rondelli, MD, James Mason, MD, Vijay Reddy, MD, PhD, Ira Braunschweig, MD, Weiyun Ai, MD, PhD, Elizabeth Armstrong, MS, Angela Smith, MS, PA, Cathy Zhao, PhD, Agnes Elekes, MD, Kazunobu Kato, MD, PhD, Edmund K. Waller, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 768.
https://doi.org/10.1182/blood.V122.21.768.768
Published: 2013
Journal Articles

Amino Acid Substitution At Peptide-Binding Pockets of HLA Class I Molecules Adversely Impacts Hematopoietic Cell Transplantation Outcomes

Joseph Pidala, MD, MS, Tao Wang, PhD, Michael D Haagenson, MS, Stephen Spellman, MBS, Medhat Askar, MD, PhD, Minoo Battiwalla, MD, MS, Lee Ann Baxter-Lowe, PhD, Menachem Bitan, MD, PhD, Marcelo Fernandez-Vina, PhD, Manish Gandhi, MD, Ann A. Jakubowski, MD, PhD, Martin Maiers, PhD, Susana R. Marino, MD, PhD, Steven GE Marsh, BSc, PhD, ARCS, Machteld Oudshoorn, PhD, Jeanne Palmer, MD, Vinod K. Prasad, MBBS, MD, MRCP, Vijay Reddy, MD, PhD, Olle Ringden, MD, PhD, Wael Saber, MD, MS, Stella Santarone, MD, Kirk R. Schultz, MD, Michelle Setterholm, Elizabeth Trachtenberg, Vicky Turner, PhD, D(ABHI), Ann Woolfrey, MD, Stephanie J. Lee, MD, MPH, Claudio Anasetti, MD
Journal: Blood
Blood (2012) 120 (21): 467.
https://doi.org/10.1182/blood.V120.21.467.467
Published: 2012
Journal Articles

Evaluation of HLA matching in unrelated hematopoietic stem cell transplantation for nonmalignant disorders

Clinical Trials & Observations
John Horan, Tao Wang, Michael Haagenson, Stephen R. Spellman, Jason Dehn, Mary Eapen, Haydar Frangoul, Vikas Gupta, Gregory A. Hale, Carolyn K. Hurley, Susana Marino, Machteld Oudshoorn, Vijay Reddy, Peter Shaw, Stephanie J. Lee, Ann Woolfrey
Journal: Blood
Blood (2012) 120 (14): 2918–2924.
https://doi.org/10.1182/blood-2012-03-417758
Published: 2012
Journal Articles

A multicenter prospective phase 2 randomized study of extracorporeal photopheresis for treatment of chronic graft-versus-host disease

Clinical Trials & Observations
Mary E. D. Flowers, Jane F. Apperley, Koen van Besien, Ahmet Elmaagacli, Andrew Grigg, Vijay Reddy, Andrea Bacigalupo, Hans-Jochem Kolb, Luis Bouzas, Mauricette Michallet, H. Miles Prince, Robert Knobler, Dennis Parenti, Jose Gallo, Hildegard T. Greinix
Journal: Blood
Blood (2008) 112 (7): 2667–2674.
https://doi.org/10.1182/blood-2008-03-141481
Published: 2008
Includes: Supplemental data
Journal Articles

A Pilot Trial of Two Dose Levels of Rabbit Antithymocyte Globulin, (rATG), Thymoglobulin, as Part of a Myeloablative-Conditioning for a HLA Identical Matched Related Donor Stem Cell Transplant (SCT) with Cyclosporine (CsA) as Graft Versus Host Disease (GvHD) Prophylaxis.

Kenneth B. Miller, MD, Nelson J. Chao, MD, Hans A. Messner, MD,PhD, Steven C. Goldstein, MD, Vijay Reddy, MD,PhD, William Vaughan, MD, Steven Devine, MD, Scott D. Rowley, MD, Ned Waller, MD,PhD, Marcel Devetten, MD, Gary J. Schiller, MD
Journal: Blood
Blood (2006) 108 (11): 5369.
https://doi.org/10.1182/blood.V108.11.5369.5369
Published: 2006
Journal Articles

A Randomized Single−Blind Study of Extracorporeal Photopheresis with UVADEX® Plus Conventional Therapy (CT) Compared to CT Alone in Chronic GVHD.

Mary E.D. Flowers, MD, Koen Van Besien, MD, Jane Apperley, MD, Andrea Bacigalupo, MD, Ahmet Elmaagacli, MD, Andrew Grigg, MD, Hans-Jochem Kolb, MD, Luis Fernando Bouzas, MD, Mauricette Michallet, MD, Vijay Reddy, MD, Jim Wang, MD, Paul Williamson, MD, Robert Knobler, MD, Hildegard Greinix, MD
Journal: Blood
Blood (2006) 108 (11): 758.
https://doi.org/10.1182/blood.V108.11.758.758
Published: 2006