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Journal Articles

Alisertib-Induced Polyploidy and Senescence in DH/DP-DLBCL Is Abrogated By Synthetic Lethal Interactions with Ibrutinib and Rituximab

Shariful Islam, MS, Wenqing Qi, PhD, Carla Morales, B.S., Laurence Cooke, M.S., Manjari Pandey, MD, Catherine M. Spier, MD, Daruka Mahadevan, MD PhD
Journal: Blood
Blood (2016) 128 (22): 5397.
https://doi.org/10.1182/blood.V128.22.5397.5397
Published: 2016
Journal Articles

Aurora Plus PI3K Inhibition Abrogates PD-L1 Induction in Peripheral T-Cell Non-Hodgkin Lymphoma

Daruka Mahadevan, MD PhD, Eric Vick, PhD, Bryan Huber, MD, Carla Morales, B.S., Laurence Cooke, M.S., Catherine M. Spier, MD, Wenqing Qi, PhD
Journal: Blood
Blood (2015) 126 (23): 1560.
https://doi.org/10.1182/blood.V126.23.1560.1560
Published: 2015
Journal Articles

Novel Targeted Combination Therapies for Peripheral T-Cell Lymphoma

Daruka Mahadevan, MD PhD, Carla Morales, BS, Bryan D. Huber, MD, Mansoor Ul Haq, MD, Catherine M. Spier, MD, Laurence S. Cooke, MS, Wenqing Qi, PhD
Journal: Blood
Blood (2014) 124 (21): 4494.
https://doi.org/10.1182/blood.V124.21.4494.4494
Published: 2014
Journal Articles

SF1126, a Pan-PI3K Inhibitor Has Superior Preclinical Activity to CAL-101 a PI3K Delta-Specific Inhibitor in Aggressive B-Cell Non-Hodgkin's Lymphoma

Daruka Mahadevan, MD, PhD, Wenqing Qi, PhD, Amy Stejskal, MA, Laurence Cooke, BA, Joseph R Garlich, PhD
Journal: Blood
Blood (2011) 118 (21): 2720.
https://doi.org/10.1182/blood.V118.21.2720.2720
Published: 2011
Journal Articles

Mitotic Spindle Assembly Inhibition Through Aurora A (MLN8237) Plus Vincristine Is Synthetic Lethal and Synergizes with Rituximab As a Curative Therapy in Aggressive B-Cell Non-Hodgkin Lymphoma

Daruka Mahadevan, MD, PhD, Laurence Cooke, BA, Amy Stejskal, MA, Ann Manziello, BS, Carla Morales, Daniel O. Persky, MD, Richard I Fisher, MD, Thomas P. Miller, MD, Wenqing Qi, PhD
Journal: Blood
Blood (2011) 118 (21): 2721.
https://doi.org/10.1182/blood.V118.21.2721.2721
Published: 2011
Journal Articles

Phase I Study of Novel Prodrug Dual PI3K/mTOR Inhibitor SF1126 In B-Cell Malignancies.

Joseph R Garlich, PhD, Michael D Becker, Candace F Shelton, Wenqing Qi, PhD, Xiaobing Liu, Laurence Cooke, Daruka Mahadevan, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1783.
https://doi.org/10.1182/blood.V116.21.1783.1783
Published: 2010
Journal Articles

AT9283, a Novel Pan-Aurora/JAK-2 Kinase Inhibitor Suppresses Tumor Growth In Aggressive B-Cell Non-Hodgkin's Lymphoma

Daruka Mahadevan, MD, PhD, Xiaobing Liu, BS, Daniel Oscar Persky, MD, Thomas P. Miller, MD, Matthew S Squires, PhD, Wenqing Qi, PhD
Journal: Blood
Blood (2010) 116 (21): 3930.
https://doi.org/10.1182/blood.V116.21.3930.3930
Published: 2010
Journal Articles

Addition of Rituximab to MLN8237 An Aurora A Kinase Inhibitor Plus Vincristine or Docetaxel Has Synergistic Anti-Tumor Activity In a Mouse Model of Aggressive B-Cell Non-Hodgkin's Lymphoma

Daruka Mahadevan, MD, PhD, Laurence Cooke, BS, Xiaobing Liu, BS, Daniel Oscar Persky, MD, Catherine M. Spier, MD, Thomas P. Miller, MD, Wenqing Qi, PhD
Journal: Blood
Blood (2010) 116 (21): 3933.
https://doi.org/10.1182/blood.V116.21.3933.3933
Published: 2010
Journal Articles

Targeting Aurora Kinase in Aggressive B-Cell Non-Hodgkin's Lymphomas.

Daruka Mahadevan, MD, PhD, Wenqing Qi, Laurence Cooke, Xiabing Lui, Daniel Oscar Persky, MD, Lisa M. Rimsza, MD, Thomas P. Miller, MD
Journal: Blood
Blood (2009) 114 (22): 284.
https://doi.org/10.1182/blood.V114.22.284.284
Published: 2009
Journal Articles

AT7519, a Potent CDK Inhibitor, Is Active in Leukemia Models and Primary CLL Patient Samples.

Matthew S. Squires, PhD, Ruth E. Feltell, BSc, Victoria Lock, Donna M. Smith, PhD, Jon E. Lewis, Jacqueline Higgins, Murray Yule, MD, Neil T. Thompson, PhD, Laurence Cooke, Kimiko D. Croce, Wenqing Qi, John F. Lyons, PhD, Daruka Mahadevan
Journal: Blood
Blood (2007) 110 (11): 3127.
https://doi.org/10.1182/blood.V110.11.3127.3127
Published: 2007