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Journal Articles

Monitoring the "Lifetime" of a Thrombus over Long Timescales By Leveraging a Novel Microvasculature-on-Chip Thrombosis Resolution Assay

Yongzhi Qiu, PhD, Yumiko Sakurai, MSc, Wilbur A. Lam, MD PhD

Blood (2019) 134 (Supplement_1): 441.

https://doi.org/10.1182/blood-2019-128718

Published: 2019

Journal Articles

Stiff Erythrocyte Subpopulations Biomechanically Induce Endothelial Inflammation in Sickle Cell Disease

Christina Caruso, MD, Xiao Zhang, BS, Yumiko Sakurai, MSc, Wei Li, MD, Meredith E. Fay, BS, Marcus A. Carden, MD, David R. Myers, PhD, Robert G. Mannino, PhD, Clinton H. Joiner, MD PhD, Michael D. Graham, PhD, Wilbur A. Lam, MD PhD

Blood (2019) 134 (Supplement_1): 3560.

https://doi.org/10.1182/blood-2019-125408

Published: 2019

Journal Articles

Increased Platelet Force Is Associated with Decreased Bleeding Severity in Pediatric Immune Thrombocytopenia

Oluwamayokun T. Oshinowo, BS, Renee Copeland, BS, Christina Caruso, MD, Meredith E. Fay, BS, Traci Leong, PhD, Carolyn M. Bennett, MDMSc, Wilbur A. Lam, MD PhD, David R. Myers, PhD

Blood (2019) 134 (Supplement_1): 1096.

https://doi.org/10.1182/blood-2019-129573

Published: 2019

Journal Articles

Mitochondrial Uncoupling Prevents Procoagulant Platelet Formation Resulting in Decreased Thrombus Stability

Andaleb Kholmukhamedov, MD, Yumiko Sakurai, MSc, Elaissa L. Hardy, PhD, Wilbur A Lam, MD PhD, Shawn M. Jobe, MD PhD

Blood (2018) 132 (Supplement 1): 2421.

https://doi.org/10.1182/blood-2018-99-117004

Published: 2018

Journal Articles

Platelet Contraction Force As a Biophysical Biomarker for Bleeding Risk in Patients with Immune Thrombocytopenia

Oluwamayokun T. Oshinowo, Renee Copeland, BS, Carolyn M. Bennett, MD MSc, Wilbur A Lam, MD PhD, David R. Myers, PhD

Blood (2018) 132 (Supplement 1): 517.

https://doi.org/10.1182/blood-2018-99-115292

Published: 2018

Journal Articles

A Comparative Medicine Study of Platelet Biophysics Among Hemostasis Models of Different Species

Renee Copeland, BS, Oluwamayokun T. Oshinowo, Yumiko Sakurai, MSc, Meredith Ellen Fay, BS, Brian G. Petrich, PhD, Benjamin Brainard, VMD, Dipl ACVAA, ACVECC, Wilbur A Lam, MD PhD, David R. Myers, PhD

Blood (2018) 132 (Supplement 1): 869.

https://doi.org/10.1182/blood-2018-99-113107

Published: 2018

Journal Articles

Real-Time Visualization of Shear-Dependent Erythrocyte Deformation into Schistocytes Using Single Micron Microfluidics

Julia Lins Arrighi Woodall, Meredith Ellen Fay, BS, Jordan Ciciliano, BS, PhD, Reza Abbaspour, BS, MS, Muhannad S Bakir, MS, PhD, Wilbur A Lam, MD PhD

Blood (2018) 132 (Supplement 1): 1030.

https://doi.org/10.1182/blood-2018-99-120113

Published: 2018

Journal Articles

A Simple, Rapid, and Inexpensive Color-Based Hemoglobin Assay As a Robust Screening Test for Severe Anemia in Limited Resource Settings

Marina Perez-Plazola, Erika Tyburski, BS, Luke R. Smart, MD, Thad A. Howard, MS, Sophie Perier, BS MS, Russell E. Ware, MD PhD, Wilbur A Lam, MD PhD, Patrick T. McGann, MD

Blood (2018) 132 (Supplement 1): 4724.

https://doi.org/10.1182/blood-2018-99-112898

Published: 2018

Journal Articles

Integrated Microfluidic Automated Particle Tracking Enables High-Throughput Cell Deformability Cytometry for Red Cell Disorders

Christina Caruso, MD, Puneeth Guruprasad, Robert G Mannino, PhD, Hanqing Zhang, PhD, Cassandra D Josephson, MD, John D Roback, MD PhD, Wilbur A Lam, MD PhD

Blood (2018) 132 (Supplement 1): 1033.

https://doi.org/10.1182/blood-2018-99-118830

Published: 2018

Journal Articles

A Microengineered Matrix to Decouple the Biophysical and Biochemical Mechanisms of Blood Cell Interactions with Thrombi and Vascular Wall Matrices

Jordan Ciciliano, BS, MS, Reza Abbaspour, Caroline Wu, Muhhanad Bakir, PhD, Wilbur A Lam, MD PhD

Blood (2016) 128 (22): 555.

https://doi.org/10.1182/blood.V128.22.555.555

Published: 2016

Journal Articles

Leveraging the Contractile Force of Platelets for Targeted Factor VIII Delivery in Hemophilia with Inhibitors

Caroline E. Hansen, BS, David R Myers, PhD, Yumiko Sakurai, MSc, Wallace Hunter Baldwin, BS, Shannon L. Meeks, MD, L. Andrew Lyon, PhD, Wilbur A Lam, MD PhD

Blood (2016) 128 (22): 81.

https://doi.org/10.1182/blood.V128.22.81.81

Published: 2016

Journal Articles

Improving Lentiviral Transduction Efficiency with Microfluidic Systems

Reginald Tran, BS, David R Myers, PhD, Jordan E Shields, MS, Byungwook Ahn, PhD, Yongzhi Qiu, PhD, Caroline Hansen, BS, Yumiko Sakurai, MSc, Robert Moot, BS, H. Trent Spencer, PhD, Christopher B Doering, PhD, Wilbur A Lam, MD PhD

Blood (2015) 126 (23): 4415.

https://doi.org/10.1182/blood.V126.23.4415.4415

Published: 2015

Journal Articles

Vessel Geometry Interacts with Red Blood Cell Stiffness to Promote Endothelial Dysfunction in Sickle Cell Disease

Yichen Wang, Robert G Mannino, BS, David R Myers, PhD, Wei Li, Clinton H. Joiner, MD PhD, Wilbur A Lam, MD PhD

Blood (2015) 126 (23): 965.

https://doi.org/10.1182/blood.V126.23.965.965

Published: 2015

Journal Articles

Clot Contraction-Mediated Erythrocyte Packing Is Significantly Altered in Sickle Cell Disease

Hunter Strauss, David R Myers, PhD, Margo Renee Rollins, MD, John W. Weisel, PhD, Wilbur A Lam, MD PhD

Blood (2015) 126 (23): 215.

https://doi.org/10.1182/blood.V126.23.215.215

Published: 2015

Journal Articles

Commonly Used Clinical Intravenous Fluid Formulations Differentially Affect Sickle Red Blood Cell Stiffness and Transit Time

Marcus A Carden, MD, Meredith Ellen Fay, BS, Yumiko Sakurai, MSc, Robert G Mannino, BS, Jordan Ciciliano, BS, Reginald Tran, BS, Wilbur A Lam, MD PhD

Blood (2015) 126 (23): 2164.

https://doi.org/10.1182/blood.V126.23.2164.2164

Published: 2015

Journal Articles

Characterizing Cellular Interactions Contributing to Vaso-Occlusion in Patients with Sickle Cell Disease Utilizing a Novel Endothelialized Microfluidic Device

Margo Renee Rollins, MD, Byungwook Ahn, PhD, Yumiko Sakurai, MSc, Wilbur A Lam, MD PhD

Blood (2015) 126 (23): 3381.

https://doi.org/10.1182/blood.V126.23.3381.3381

Published: 2015

Journal Articles

Engineering a "Self-Healing" Hydrogel-Based Microvasculature-on-a-Chip for Investigating the Effects of Cellular and Biomolecular Interactions on Endothelial Permeability in Sickle Cell Disease

Yongzhi Qiu, PhD, Byungwook Ahn, PhD, Yumiko Sakurai, MSc, Caroline Hansen, BS, Clinton H. Joiner, MD PhD, Solomon Fiifi Ofori-Acquah, PhD, Wilbur A Lam, MD PhD

Blood (2015) 126 (23): 240.

https://doi.org/10.1182/blood.V126.23.240.240

Published: 2015

Journal Articles

Engineering a Valve-Regulated Endothelialized Microfluidic Device As an " in Vitro " Bleeding Time for Assessing Global Hemostasis

Yumiko Sakurai, MSc, Elaissa T. Hardy, PhD, Byungwook Ahn, PhD, Shannon L. Meeks, MD, W. Hunter Baldwin, BS, Shawn M Jobe, MD PhD, Wilbur A Lam, MD PhD

Blood (2015) 126 (23): 3485.

https://doi.org/10.1182/blood.V126.23.3485.3485

Published: 2015

Journal Articles

Vascular Geometry and Flow Profile Mediate Pathological Cell-Cell Interactions in Sickle Cell Disease As Measured with "Do-It-Yourself" "Endothelial-Ized" Microfluidics

Robert Mannino, BS, David R Myers, PhD, Byungwook Ahn, PhD, Hope Gole, PhD, Yichen Wang, Angela Lin, Robert Guldberg, PhD, Don Giddens, PhD, Lucas Timmins, PhD, Wilbur A Lam, MD PhD

Blood (2014) 124 (21): 454.

https://doi.org/10.1182/blood.V124.21.454.454

Published: 2014

Journal Articles

Investigating Platelet Interactions in Sickle Cell Disease Using a Novel Multi-Shear "Endothelialized" Microfluidic System

Margo Renee Rollins, MD, Byungwook Ahn, PhD, Yumiko Sakurai, MSc, Jordan C Ciciliano, BS, Wilbur A Lam, MD PhD

Blood (2014) 124 (21): 4155.

https://doi.org/10.1182/blood.V124.21.4155.4155

Published: 2014

NARROW

Monitoring the "Lifetime" of a Thrombus over Long Timescales By Leveraging a Novel Microvasculature-on-Chip Thrombosis Resolution Assay

Stiff Erythrocyte Subpopulations Biomechanically Induce Endothelial Inflammation in Sickle Cell Disease

Increased Platelet Force Is Associated with Decreased Bleeding Severity in Pediatric Immune Thrombocytopenia

Mitochondrial Uncoupling Prevents Procoagulant Platelet Formation Resulting in Decreased Thrombus Stability

Platelet Contraction Force As a Biophysical Biomarker for Bleeding Risk in Patients with Immune Thrombocytopenia

A Comparative Medicine Study of Platelet Biophysics Among Hemostasis Models of Different Species

Real-Time Visualization of Shear-Dependent Erythrocyte Deformation into Schistocytes Using Single Micron Microfluidics

A Simple, Rapid, and Inexpensive Color-Based Hemoglobin Assay As a Robust Screening Test for Severe Anemia in Limited Resource Settings

Integrated Microfluidic Automated Particle Tracking Enables High-Throughput Cell Deformability Cytometry for Red Cell Disorders

A Microengineered Matrix to Decouple the Biophysical and Biochemical Mechanisms of Blood Cell Interactions with Thrombi and Vascular Wall Matrices

Leveraging the Contractile Force of Platelets for Targeted Factor VIII Delivery in Hemophilia with Inhibitors

Improving Lentiviral Transduction Efficiency with Microfluidic Systems

Vessel Geometry Interacts with Red Blood Cell Stiffness to Promote Endothelial Dysfunction in Sickle Cell Disease

Clot Contraction-Mediated Erythrocyte Packing Is Significantly Altered in Sickle Cell Disease

Commonly Used Clinical Intravenous Fluid Formulations Differentially Affect Sickle Red Blood Cell Stiffness and Transit Time

Characterizing Cellular Interactions Contributing to Vaso-Occlusion in Patients with Sickle Cell Disease Utilizing a Novel Endothelialized Microfluidic Device

Engineering a "Self-Healing" Hydrogel-Based Microvasculature-on-a-Chip for Investigating the Effects of Cellular and Biomolecular Interactions on Endothelial Permeability in Sickle Cell Disease

Engineering a Valve-Regulated Endothelialized Microfluidic Device As an " in Vitro " Bleeding Time for Assessing Global Hemostasis

Vascular Geometry and Flow Profile Mediate Pathological Cell-Cell Interactions in Sickle Cell Disease As Measured with "Do-It-Yourself" "Endothelial-Ized" Microfluidics

Investigating Platelet Interactions in Sickle Cell Disease Using a Novel Multi-Shear "Endothelialized" Microfluidic System

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American Society of Hematology

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ASH Publications

American Society of Hematology

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