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Journal Articles

Interaction of Mantle Cell Lymphoma with the Microenvironment Induces Phospho Akt-Mediated Resistance Against BTK Inhibition and Can be Overcome By Co-Treatment with a Specific Akt Inhibitor (MK-2206)

Elisabeth Silkenstedt, MD, Claudia Schwandner, Johanna Deuss, Natalie Mack, Yvonne Zimmermann, Martin Dreyling, MD

Blood (2019) 134 (Supplement_1): 2802.

https://doi.org/10.1182/blood-2019-128782

Published: 2019

Journal Articles

Cotargeting of PIM, PI3K and Mtor in Mantle Cell Lymphoma (MCL)

Bianca Freysoldt, Andrea Schnaiter, MD, Luca Fischer, Michael O'Neill, PhD, Yvonne Zimmermann, Grit Hutter, Wolfgang Hiddemann, MD, Martin H. Dreyling, MD PhD

Blood (2015) 126 (23): 5120.

https://doi.org/10.1182/blood.V126.23.5120.5120

Published: 2015

Journal Articles

The Novel CDK4/6-Inhibitor Abemaciclib Induces Early G1-Arrest in MCL Cell Lines, Sensitizes Cells to Cytarabine Treatment and Is Additive with Ibrutinib

Luca Fischer, Andrea Schnaiter, MD, Bianca Freysoldt, Markus Irger, Yvonne Zimmermann, Grit Hutter, Wolfgang Hiddemann, MD, Martin H. Dreyling, MD PhD

Blood (2015) 126 (23): 5124.

https://doi.org/10.1182/blood.V126.23.5124.5124

Published: 2015

Journal Articles

Gray platelet syndrome can mimic autoimmune lymphoproliferative syndrome

Anne Rensing-Ehl, Ulrich Pannicke, Stefanie-Yvonne Zimmermann, Myriam Ricarda Lorenz, Benedicte Neven, Ilka Fuchs, Ulrich Salzer, Carsten Speckmann, Anne Strauss, Eberhard Maaβ, Benedicte Collet, Anselm Enders, Remi Favier, Marie Christine Alessi, Frederic Rieux-Laucat, Barbara Zieger, Klaus Schwarz, Stephan Ehl

Blood (2015) 126 (16): 1967–1969.

https://doi.org/10.1182/blood-2015-06-654145

Published: 2015

Journal Articles

Combination of PI3K and PDPK1 Inhibitors Is Highly Effective in Mantle Cell Lymphoma

Grit Hutter, PhD, Yvonne Zimmermann, Anna-Katharina Zoellner, MD, Philip Irrgang, Oliver Weigert, MD, Wolfgang Hiddemann, MD, Martin Dreyling

Blood (2014) 124 (21): 3123.

https://doi.org/10.1182/blood.V124.21.3123.3123

Published: 2014

Journal Articles

Rituximab But Not GA101 Is Partially Antagonistic With Inhibitors Of The B-Cell Receptor Pathway In Diffuse Large B-Cell Lymphoma

Anna-Katharina Zoellner, Nico Peter, Grit Hutter, Yvonne Zimmermann, Wolfgang Hiddemann, MD, Martin Dreyling

Blood (2013) 122 (21): 4420.

https://doi.org/10.1182/blood.V122.21.4420.4420

Published: 2013

Journal Articles

High Efficiency Of the PDPK1-Inhibitor, BX912, In MCL

Grit Hutter, Yvonne Zimmermann, Vladimir Giller, Anna-Katharina Zoellner, Oliver Weigert, Wolfgang Hiddemann, M.D., Martin Dreyling

Blood (2013) 122 (21): 3077.

https://doi.org/10.1182/blood.V122.21.3077.3077

Published: 2013

Journal Articles

Differential Regulation Patterns of Anti-CD20 Antibodies GA101 and Rituximab in Mantle Cell Lymphoma

Daniel Heinrich, Marc Weinkauf, Grit Hutter, Kristina Decheva, Yvonne Zimmermann, Wolfgang Hiddemann, MD, Martin H. Dreyling, MD

Blood (2010) 116 (21): 1839.

https://doi.org/10.1182/blood.V116.21.1839.1839

Published: 2010

Journal Articles

Proteasome Inhibition Leads to Dephosphorylation and Downregulation of Protein Expression of Members of the Akt/mTOR Pathway In MCL

Grit Hutter, Yvonne Zimmermann, Malte Rieken, Elena Hartmann, Wolfgang Hiddemann, MD, PhD, Andreas Rosenwald, Martin H. Dreyling, MD

Blood (2010) 116 (21): 4449.

https://doi.org/10.1182/blood.V116.21.4449.4449

Published: 2010

Journal Articles

Enzastaurin Treatment Affects Multiple Regulatory Pathways at Transcriptome and Cellular Proteome Level of Mantle Cell Lymphoma

Marc Weinkauf, Grit Hutter, Yvonne Zimmermann, Malte Rieken, Alessandro Pastore, Elena Hartmann, Andreas Rosenwald, Wolfgang Hiddemann, MD, Martin H. Dreyling, MD

Blood (2010) 116 (21): 2893.

https://doi.org/10.1182/blood.V116.21.2893.2893

Published: 2010

Journal Articles

Anti-CD20 Antibody GA101 in Combination with Chemotherapy or Flavopiridol in Mantle Cell Lymphoma.

Daniel A. Heinrich, Christian Klein, Kristina Decheva, Marc Weinkauf, Grit Hutter, Yvonne Zimmermann, Tobias Weiglein, Wolfgang Hiddemann, Martin H. Dreyling

Blood (2009) 114 (22): 4781.

https://doi.org/10.1182/blood.V114.22.4781.4781

Published: 2009

Journal Articles

Synergistic Antilymphoma Effect of Protein Kinase C Beta (PKCβ) and mTOR Inhibition in Mantle Cell Lymphoma.

Grit Hutter, Yvonne Zimmermann, Malte Rieken, Elena Hartmann, MD, Vindi Jurinovic, Andreas Rosenwald, Marc Weinkauf, Wolfgang Hiddemann, Martin H. Dreyling

Blood (2009) 114 (22): 4780.

https://doi.org/10.1182/blood.V114.22.4780.4780

Published: 2009

Journal Articles

Anti-CD20 Antibody GA101 Shows Higher Cytotoxicity but Is Competitively Displaced by Rituximab in Mantle Cell Lymphoma.

Daniel A. Heinrich, Christian Klein, Kristina Decheva, Marc Weinkauf, Grit Hutter, Yvonne Zimmermann, Tobias Weiglein, Wolfgang Hiddemann, Martin H. Dreyling

Blood (2009) 114 (22): 2704.

https://doi.org/10.1182/blood.V114.22.2704.2704

Published: 2009

Journal Articles

RNA-Expression and Proteome Analysis Identify Complementary but Not Identical Molecular Targets in Enzastaurin-Treated Mantle Cell Lymphoma.

Marc Weinkauf, Grit Hutter, Yvonne Zimmermann, Elena Hartmann, MD, Andreas Rosenwald, Wolfgang Hiddemann, Martin H. Dreyling

Blood (2009) 114 (22): 1915.

https://doi.org/10.1182/blood.V114.22.1915.1915

Published: 2009

Journal Articles

Regulation of the Cyclin D1 Proto-Oncogene by Cell Cycle Regulatory MicroRNAs.

Anagha Borwankar, Alessandro Pastore, Aniruddha Deshpande, Yvonne Zimmermann, Christian Buske, Wolfgang Hiddemann, Martin Dreyling

Blood (2008) 112 (11): 1801.

https://doi.org/10.1182/blood.V112.11.1801.1801

Published: 2008

Journal Articles

The Functional Impact of PKCβ/PI3K/AKT Signalling on Translational Initiation in MCL

Grit Hutter, Yvonne Zimmermann, Marc Weinkauf, Alina Postnikova, Tobias Weiglein, Wolfgang Hiddemann, Martin Dreyling

Blood (2008) 112 (11): 2624.

https://doi.org/10.1182/blood.V112.11.2624.2624

Published: 2008

Journal Articles

TRAIL Receptor 1 and TRAIL Receptor 2 Monoclonal Antibodies Induce Apoptosis and Increase Susceptibility to Cytostatic Agents in Mantle Cell Lymphoma.

Malte Rieken, MD, Alessandro Pastore, MD, Oliver Weigert, MD, Marc Weinkauf, MD, Grit Hutter, MD, Yvonne Zimmermann, MD, Wolfgang Hiddemann, MD, Martin Dreyling, MD

Blood (2006) 108 (11): 4751.

https://doi.org/10.1182/blood.V108.11.4751.4751

Published: 2006

Journal Articles

Inhibition of Proteasome Is Associated with Early Alterations of Cell Cycle Regulators and Induces Synergistic Antitumour Activities in Mantle Cell Lymphoma in a Sequence Dependent Manner.

Alessandro Pastore, Malte Rieken, Oliver Weigert, MD, Yvonne Zimmermann, Grit Hutter, PhD, Marc Weinkauf, Wolfgang Hiddemann, MD, PhD, Martin Dreyling, MD, PhD

Blood (2005) 106 (11): 2409.

https://doi.org/10.1182/blood.V106.11.2409.2409

Published: 2005

Journal Articles

Inhibition of Protein Kinase C beta by Enzastaurin (LY 317615) Induces Alterations of Key Regulators of Cell Cycle and Apoptosis in Mantle Cell Lymphoma and Synergizes with Chemotherapeutic Agents in a Sequence Dependent Manner.

Malte Rieken, Oliver Weigert, MD, Alessandro Pastore, Grit Hutter, PhD, Yvonne Zimmermann, Marc Weinkauf, Wolfgang Hiddemann, MD, PhD, Martin Dreyling, MD, PhD

Blood (2005) 106 (11): 2416.

https://doi.org/10.1182/blood.V106.11.2416.2416

Published: 2005

Journal Articles

Cell Cycle Dysregulation Represents an Early Effect of the Proteasome Inhibitor Bortezomib in Mantle Cell Lymphoma.

Grit Hutter, MSc, Yvonne Zimmermann, Malte Rieken, Marc Weinkauf, Oliver Weigert, MD, Wolfgang Hiddemann, MD, PhD, Martin H. Dreyling, MD, PhD

Blood (2004) 104 (11): 2287.

https://doi.org/10.1182/blood.V104.11.2287.2287

Published: 2004

NARROW

Interaction of Mantle Cell Lymphoma with the Microenvironment Induces Phospho Akt-Mediated Resistance Against BTK Inhibition and Can be Overcome By Co-Treatment with a Specific Akt Inhibitor (MK-2206)

Cotargeting of PIM, PI3K and Mtor in Mantle Cell Lymphoma (MCL)

The Novel CDK4/6-Inhibitor Abemaciclib Induces Early G1-Arrest in MCL Cell Lines, Sensitizes Cells to Cytarabine Treatment and Is Additive with Ibrutinib

Gray platelet syndrome can mimic autoimmune lymphoproliferative syndrome

Combination of PI3K and PDPK1 Inhibitors Is Highly Effective in Mantle Cell Lymphoma

Rituximab But Not GA101 Is Partially Antagonistic With Inhibitors Of The B-Cell Receptor Pathway In Diffuse Large B-Cell Lymphoma

High Efficiency Of the PDPK1-Inhibitor, BX912, In MCL

Differential Regulation Patterns of Anti-CD20 Antibodies GA101 and Rituximab in Mantle Cell Lymphoma

Proteasome Inhibition Leads to Dephosphorylation and Downregulation of Protein Expression of Members of the Akt/mTOR Pathway In MCL

Enzastaurin Treatment Affects Multiple Regulatory Pathways at Transcriptome and Cellular Proteome Level of Mantle Cell Lymphoma

Anti-CD20 Antibody GA101 in Combination with Chemotherapy or Flavopiridol in Mantle Cell Lymphoma.

Synergistic Antilymphoma Effect of Protein Kinase C Beta (PKCβ) and mTOR Inhibition in Mantle Cell Lymphoma.

Anti-CD20 Antibody GA101 Shows Higher Cytotoxicity but Is Competitively Displaced by Rituximab in Mantle Cell Lymphoma.

RNA-Expression and Proteome Analysis Identify Complementary but Not Identical Molecular Targets in Enzastaurin-Treated Mantle Cell Lymphoma.

Regulation of the Cyclin D1 Proto-Oncogene by Cell Cycle Regulatory MicroRNAs.

The Functional Impact of PKCβ/PI3K/AKT Signalling on Translational Initiation in MCL

TRAIL Receptor 1 and TRAIL Receptor 2 Monoclonal Antibodies Induce Apoptosis and Increase Susceptibility to Cytostatic Agents in Mantle Cell Lymphoma.

Inhibition of Proteasome Is Associated with Early Alterations of Cell Cycle Regulators and Induces Synergistic Antitumour Activities in Mantle Cell Lymphoma in a Sequence Dependent Manner.

Inhibition of Protein Kinase C beta by Enzastaurin (LY 317615) Induces Alterations of Key Regulators of Cell Cycle and Apoptosis in Mantle Cell Lymphoma and Synergizes with Chemotherapeutic Agents in a Sequence Dependent Manner.

Cell Cycle Dysregulation Represents an Early Effect of the Proteasome Inhibitor Bortezomib in Mantle Cell Lymphoma.

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American Society of Hematology

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American Society of Hematology

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