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Journal Articles

Frequency and Clinical Characteristics Associated with Putative CAR Targets ADGRE2, CCR1, CD70, and LILRB2 in Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 5259.

https://doi.org/10.1182/blood-2018-99-113037

Published: 2018

Journal Articles

Synergy between FLT3-ITD and p53 Haploinsufficiency or Loss in the Development of Acute Myeloid Leukemia

Zengkai Pan, MD PhD, Min Yang, Kezhi Huang, MD PhD, Guntram Buesche, MD, Gudrun Göhring, MD, Michaela Scherr, PhD, Matthias Gaestel, PhD, Matthias Eder, MD, Julia Skokowa, MDPhD, Jianfeng Zhou, PhD, Karl Welte, Li-Gen Liu, MD, Arnold Ganser, MD, Zhixiong Li, MD

Blood (2018) 132 (Supplement 1): 771.

https://doi.org/10.1182/blood-2018-99-110770

Published: 2018

Journal Articles

Targeting Rac-Gtpases Reverses Stroma-Induced Resistance to Notch and mTOR-Inhibition in Acute T-Cell Leukemia

Adrian Schwarzer, MD PhD, Martin May, Harald Genth, Zhixiong Li, MD, Christopher Baum, MD, Axel Schambach, MD PhD

Blood (2015) 126 (23): 1326.

https://doi.org/10.1182/blood.V126.23.1326.1326

Published: 2015

Journal Articles

The Novel FLT3-N676K Mutant Induces Acute Leukemia Independently of the Inv(16) Chimeric Gene CBFB-MYH11

Kezhi Huang, Min Yang, Zengkai Pan, Florian H. Heidel, MD, Michaela Scherr, PhD, Matthias Eder, MD, Thomas Fischer, MD, Guntram Buesche, MD, Nils von Neuhoff, PhD, Arnold Ganser, MD, Zhixiong Li, MD

Blood (2015) 126 (23): 1383.

https://doi.org/10.1182/blood.V126.23.1383.1383

Published: 2015

Journal Articles

Investigating Synthetic Lethality Between mTOR Hyperactivation and Cap-Dependent mRNA Translation In a Receptor Tyrosine Kinase Driven Model Of Acute T-Cell Leukemia

Adrian Schwarzer, MD PhD, Helmut Holtmann, PhD, Celina Schauerte, M.Sc., Nomme Benn, Jan Völkel, Sabine Knöß, Johannes Zuber, MD, Zhixiong Li, MD, Axel Schambach, MD PhD, Christopher Baum, MD

Blood (2013) 122 (21): 3913.

https://doi.org/10.1182/blood.V122.21.3913.3913

Published: 2013

Journal Articles

Receptor Tyrosine Kinases, Notch Mutations and PTEN Loss Converge On mTOR in T-ALL and Cause Addiction to Cap Dependent mRNA Translation.

Adrian Schwarzer, MD, Helmut Holtmann, PhD, Martijn Brugman, PhD, Johann Meyer, PhD, Doris Steinemann, PhD, Brigitte Schlegelberger, Zhixiong Li, MD, Christopher Baum, MD

Blood (2012) 120 (21): 2415.

https://doi.org/10.1182/blood.V120.21.2415.2415

Published: 2012

Journal Articles

Mutated IDH1 Has 2-Hydroxyglutarate-Independent Functions in Leukemogenesis

Blood (2012) 120 (21): 770.

https://doi.org/10.1182/blood.V120.21.770.770

Published: 2012

Journal Articles

Evidence for Cooperation of Receptor Tyrosine Kinases and Activating NOTCH Mutations to Hyperactivate mTOR in T-Cell Leukemia: A Rationale Basis for Targeted Therapy

Adrian Schwarzer, MD, Johann Meyer, PhD, Martijn Brugman, PhD, Axel Schambach, MD PhD, Martin Stanulla, MD, MSc, Martin Schrappe, MD, Doris Steinemann, PhD, Brigitte Schlegelberger, M.D., Christopher Baum, MD, Zhixiong Li, MD

Blood (2011) 118 (21): 1381.

https://doi.org/10.1182/blood.V118.21.1381.1381

Published: 2011

Journal Articles

Leukemia Induced by Altered TRK-Signaling Is Sensitive to Rapamycin Treatment in a Preclinical Model

Mathias Rhein, Min Yang, Volkhard Kaever, PhD, Johann Meyer, PhD, Christopher Baum, MD, Zhixiong Li, MD

Blood (2008) 112 (11): 2851.

https://doi.org/10.1182/blood.V112.11.2851.2851

Published: 2008

Journal Articles

Ectopic Expression of the Extracellular Domain of Mpl Is Sufficient to Induce a Hematopoietic Population Crisis

Daniel C. Wicke, Johann Meyer, Guntram Büsche, MD, Hans Kreipe, MD, Zhixiong Li, MD, Karl Welte, Matthias Ballmaier, Christopher Baum, Ute Modlich

Blood (2008) 112 (11): 2886.

https://doi.org/10.1182/blood.V112.11.2886.2886

Published: 2008

Journal Articles

Neurotrophin Receptors and Ligands Are Highly Expressed in Acute Leukemia and Promote Leukemogenesis.

Zhixiong Li, MD, Gernot Beutel, MD, Johann Meyer, PhD, Christian Koenecke, MD, Thomas Neumann, Min Yang, Juergen Krauter, MD, Mathias Rhein, Msc, Nils von Neuhoff, PhD, Michael Heuser, MD, Helmut Diedrich, MD, Ludwig Wilkens, MD, Brigitte Schlegelberger, MD, Arnold Ganser, MD, Christopher Baum, MD

Blood (2007) 110 (11): 696.

https://doi.org/10.1182/blood.V110.11.696.696

Published: 2007

Journal Articles

A Comparative Analysis of the Leukaemic Potential of Mature T Cells Versus T Cell Precursors.

Sebastian Newrzela, Christopher Baum, MD, Zhixiong Li, MD, Martin-Leo Hansmann, MD, Sylvia Hartmann, MD, Marianne Hartmann, Kerstin Cornils, Boris Fehse, MD, Dorothee M. von Laer, MD

Blood (2006) 108 (11): 3248.

https://doi.org/10.1182/blood.V108.11.3248.3248

Published: 2006

Journal Articles

Leukemogenic Cascade Induced by a Constitutively Active Neurotrophin Receptor, ΔTrkA.

Zhixiong Li, MD, Johann Meyer, PhD, Mathias Rhein, Olga Kustikova, PhD, Cornelia Rudolph, PhD, Kenji Kamino, MD, Thomas Neumann, Min Yang, BSc, Anke Wahlers, PhD, Boris Fehse, PhD, Gary W. Reuther, PhD, Brigitte Schlegelberger, MD, Arnold Ganser, MD, Christopher Baum, MD

Blood (2006) 108 (11): 1442.

https://doi.org/10.1182/blood.V108.11.1442.1442

Published: 2006

Journal Articles

Insertion Sites of Retroviral Gene-Marking Vectors Influence the Contribution of Individual, Non-Malignant Cell Clones to Long-Term Hematopoiesis.

Olga Kustikova, PhD, Zhixiong Li, MD, Christopher Baum, MD, Boris Fehse, PhD

Blood (2004) 104 (11): 293.

https://doi.org/10.1182/blood.V104.11.293.293

Published: 2004

Journal Articles

More Than One Mutation Is Required for Leukemia Development Following Retroviral Vector-Mediated Gene Transfer.

Olga Kustikova, PhD, Manfred Schmidt, PhD, Ute Modlich, PhD, Zhixiong Li, MD, Sonja Schmidt, Anette Deichmann, PhD, Cornelia Rudolph, Nils von Neuhoff, PhD, Brigitte Schlegelberger, MD, Boris Fehse, MD, Christof Kalle, MD, Christopher Baum, MD

Blood (2004) 104 (11): 294.

https://doi.org/10.1182/blood.V104.11.294.294

Published: 2004

NARROW

Frequency and Clinical Characteristics Associated with Putative CAR Targets ADGRE2, CCR1, CD70, and LILRB2 in Acute Myeloid Leukemia

Synergy between FLT3-ITD and p53 Haploinsufficiency or Loss in the Development of Acute Myeloid Leukemia

Targeting Rac-Gtpases Reverses Stroma-Induced Resistance to Notch and mTOR-Inhibition in Acute T-Cell Leukemia

The Novel FLT3-N676K Mutant Induces Acute Leukemia Independently of the Inv(16) Chimeric Gene CBFB-MYH11

Investigating Synthetic Lethality Between mTOR Hyperactivation and Cap-Dependent mRNA Translation In a Receptor Tyrosine Kinase Driven Model Of Acute T-Cell Leukemia

Receptor Tyrosine Kinases, Notch Mutations and PTEN Loss Converge On mTOR in T-ALL and Cause Addiction to Cap Dependent mRNA Translation.

Mutated IDH1 Has 2-Hydroxyglutarate-Independent Functions in Leukemogenesis

Evidence for Cooperation of Receptor Tyrosine Kinases and Activating NOTCH Mutations to Hyperactivate mTOR in T-Cell Leukemia: A Rationale Basis for Targeted Therapy

Leukemia Induced by Altered TRK-Signaling Is Sensitive to Rapamycin Treatment in a Preclinical Model

Ectopic Expression of the Extracellular Domain of Mpl Is Sufficient to Induce a Hematopoietic Population Crisis

Neurotrophin Receptors and Ligands Are Highly Expressed in Acute Leukemia and Promote Leukemogenesis.

A Comparative Analysis of the Leukaemic Potential of Mature T Cells Versus T Cell Precursors.

Leukemogenic Cascade Induced by a Constitutively Active Neurotrophin Receptor, ΔTrkA.

Insertion Sites of Retroviral Gene-Marking Vectors Influence the Contribution of Individual, Non-Malignant Cell Clones to Long-Term Hematopoiesis.

More Than One Mutation Is Required for Leukemia Development Following Retroviral Vector-Mediated Gene Transfer.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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