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Journal Articles

Alternative Splicing and Intronic Polyadenylation Post-Transcriptionally Regulate CSF3R Via a Cryptic Exon

Lawrence J Druhan, PhD, Amanda Lance, MS, Alicia Hamilton, Nury M Steuerwald, PhD, Elise Tjaden, Belinda R Avalos, MD

Blood (2019) 134 (Supplement_1): 2462.

https://doi.org/10.1182/blood-2019-129102

Published: 2019

Journal Articles

A Signature of Differentially Expressed Micrornas in Lymphoblastoid Cells from Shwachman-Diamond Syndrome Patients Indicates Possible Molecular Targets for Mirna Therapeutics

Jessica Gasparello, PhD, Chiara Papi, Giulia Breveglieri, PhD, Elisabetta D'Aversa, PhD, Valentino Bezzerri, PhD, Giovanna D'Amico, BSc, PhD MSc, Marco Cipolli, MD, Roberto Gambari, PhD, Monica Borgatti, PhD, Alessia Finotti, PhD

Blood (2019) 134 (Supplement_1): 2504.

https://doi.org/10.1182/blood-2019-128607

Published: 2019

Journal Articles

Somatic Mutations and Loss of Heterozygosity of HLA Genes Are Frequently Occurred and Tightly Associated with Poor Prognosis in Adult T Cell Leukemia-Lymphoma

Keita Tamaki, MD, Satoko Morishima, MD PhD, Shingo Suzuki, PhD, Atsuko Shigenari, Ikumi Nomura, Yutaro Yokota, Kazuho Morichika, MD, Yukiko Nishi, MD PhD, Sawako Nakachi, MD PhD, Shiki Okamoto, PhD, Kennosuke Karube, MD PhD, Takuya Fukushima, MD PhD, Takashi Shiina, PhD, Hiroaki Masuzaki, MD PhD

Blood (2019) 134 (Supplement_1): 2785.

https://doi.org/10.1182/blood-2019-128070

Published: 2019

Journal Articles

The Metabolic Enzyme Hexokinase 2 Localizes to the Nucleus in AML and Normal Hematopoietic Stem/Progenitor Cells to Maintain Stemness

Geethu Emily Thomas, PhDMSc,BSc, Grace Egan, MD, Laura Garcia Prat, Boaz Nachmias, MD PhD, Jordan M Chin, Fieke W Hoff, BSc, Kerstin Kaufmann, PhD, Rose Hurren, BSc, Marcela Gronda, MSc, Neil MacLean, Xiaoming Wang, Veronique Voisin, PhD, Aaron Botham, Andrea Arruda, Mark D. Minden, MD PhD, Gary D Bader, Steven M. Kornblau, MD, John E. Dick, PhD, Aaron D Schimmer, MD PhD

Blood (2019) 134 (Supplement_1): 2532.

https://doi.org/10.1182/blood-2019-123121

Published: 2019

Journal Articles

shRNA-Interleukin-6 Modified CD19-Specific Chimeric Antigen Receptor T Cell Significantly Improves the Safety in Acute Lymphoblastic Leukemia

Liqing Kang, Xiaowen Tang, Nan Xu, Minghao Li, Jingwen Tan, Wei Qi, Zhou Yu, Xiaoyan Lou, Shengli Xue, Xin Li, MD, Jian Zhang, MD, Jia Chen, MD, Zhenkun Wang, PhD, Caixia Li, Fu Cheng Cheng, MD PhD, Depei Wu, MD PhD, Lei Yu, MD PhD

Blood (2019) 134 (Supplement_1): 2621.

https://doi.org/10.1182/blood-2019-132067

Published: 2019

Journal Articles

Mutation Profile of PPM1D and TP53 in Patients with Myelodysplastic Syndromes and Complex Chromosome Abnormalities

Blood (2019) 134 (Supplement_1): 2994.

https://doi.org/10.1182/blood-2019-126778

Published: 2019

Journal Articles

Genome Data Allow in silico Pharmacogenetic Studies Using the Genetic Makeup of Both the Individual Patient As Well As the Disease

Manja Meggendorfer, PhD, Wencke Walter, PhD, Stephan Hutter, PhD, Constance Baer, PhD, Claudia Haferlach, MD, Wolfgang Kern, MD, Torsten Haferlach, MD

Blood (2019) 134 (Supplement_1): 3360.

https://doi.org/10.1182/blood-2019-126580

Published: 2019

Journal Articles

Addiction of B Cell Lymphomas to microRNA-17-92 Is Mediated By a Single Target Gene

Katia Schoeler, Teresa Mittermeier, Andreas Villunger, Klaus Rajewsky, MD, Verena Labi, PhD

Blood (2019) 134 (Supplement_1): 1258.

https://doi.org/10.1182/blood-2019-126483

Published: 2019

Journal Articles

Lineage Tracing in Chronic Lymphocytic Leukemia Reveals Clones with Stable Gene Expression States That Differentially Respond to Therapy

Catherine Gutierrez, Aziz Al'Khafaji, B.S., Eric Brenner, B.S., Russell Durrett, B.S., M.S., Kaitlyn Johnson, B.S., M.S., Wandi Zhang, MD, Shuqiang Li, PhD, Kenneth J. Livak, PhD, Donna S Neuberg, ScD, Amy Brock, PhD, Catherine J. Wu, MD

Blood (2019) 134 (Supplement_1): 1229.

https://doi.org/10.1182/blood-2019-129303

Published: 2019

Journal Articles

Treosulfan Metabolite (S, S-EBDM) Pharmacokinetics Influences Regimen Related Toxicity in Patients with Beta Thalassaemia Major Undergoing HSCT

Aswin Anand PAI, MSc, John C Panetta, PhD, Ezhil Pavai Mohanan, PhD, Raveen Stephen Stallon Illangeswaran, MSc, Balaji Balakrishnan, PhD, Eunice Sindhuvi Edison, PhD, Kavitha M Lakshmi, MSc, Uday Prakash Kulkarni, MD DM, Anup Joseph Devasia, MD DM, Fouzia N., Anu Korula, MD DM, Aby Abraham, MD DM, Biju George, MDDM, Vikram Mathews, MD DM, Alok Srivastava, MD,FRACP,FRCPA, Poonkuzhali Balasubramanian, PhD

Blood (2019) 134 (Supplement_1): 1977.

https://doi.org/10.1182/blood-2019-125604

Published: 2019

Journal Articles

CRISPR-Cas9 Screen Identifies Me2 , a Mitochondrial Malic Enzyme, As a Molecule Relevant for MCL1 Inhibitor Resistance in AML

Fumihiko Nakao, MD, Takuji Yamauchi, MD PhD, Yuichiro Semba, MD PhD, Jumpei Nogami, PhD, Koichi Akashi, MD PhD, Takahiro Maeda, MD PhD

Blood (2019) 134 (Supplement_1): 912.

https://doi.org/10.1182/blood-2019-129237

Published: 2019

Journal Articles

Single Nucleotide Polymorphisms in SAR1A Codon Regions Associated with Hydroxyurea Response in Sickle Cell Disease and Potentially Influenced in Mirnas Binding

Chutima Kumkhaek, PhD, Christine Kim, James G. Taylor, MD, Jianqiong Zhu, MD, Wulin Aerbajinai, MD, Griffin Rodgers, MD

Blood (2019) 134 (Supplement_1): 987.

https://doi.org/10.1182/blood-2019-124965

Published: 2019

Journal Articles

Interleukin-15 (IL-5) in Combination with Avelumab in Relapsed/Refractory Mature T-Cell Malignancies

Milos D. Miljkovic, MDMSc, Kevin C Conlon, MD, Sigrid Dubois, PhD, Jennifer Hsu, RN, Jeffrey Schlom, PhD, James Gulley, MD PhD, Thomas A. Waldmann, MD

Blood (2019) 134 (Supplement_1): 1558.

https://doi.org/10.1182/blood-2019-128945

Published: 2019

Journal Articles

Downregulation of MDM2 Leads to Anti-Proliferative Effects through Activation of p53-Associated Pathway Mediated By Both Dual Inhibitor MX69 and Mir-548c-3p in Multiple Myeloma

Faruq Faruq, PhD, Davidson Zhao, Jian Wu, MD, Jonahunnatha Nesson George William, PhD, Min Zhang, MD, Hong Chang, MD

Blood (2019) 134 (Supplement_1): 4419.

https://doi.org/10.1182/blood-2019-129430

Published: 2019

Journal Articles

IRF4 Is Reciprocally Dysregulated Via NF-Κb-Dependent Expression and Loss-of-Function Mutations in Multiple Myeloma

Yun Dai, MD, Yue Sun, MS, Shaji K. Kumar, MD, Wei Wu, MD, Fengyan Jin, MD PhD

Blood (2019) 134 (Supplement_1): 687.

https://doi.org/10.1182/blood-2019-132051

Published: 2019

Journal Articles

Proof of Concept for Tipifarnib in Relapsed or Refractory Angioimmunoblastic T-Cell Lymphoma (AITL) and CXCL12+ Peripheral T-Cell Lymphoma (PTCL): Preliminary Results from an Open-Label, Phase 2 Study

Blood (2019) 134 (Supplement_1): 468.

https://doi.org/10.1182/blood-2019-128513

Published: 2019

Journal Articles

FIP1L1 Regulates Alternative Polyadenylation of Leukemia-Associated Genes in Acute Myeloid Leukemia

Amanda G Davis, BS, Takahiro Shima, MD PhD, Ruijia Wang, PhD, Dinghai Zheng, PhD, Bin Tian, PhD, Dong-Er Zhang, PhD

Blood (2018) 132 (Supplement 1): 3882.

https://doi.org/10.1182/blood-2018-99-119582

Published: 2018

Journal Articles

Research of miR-30b in Cisplatin Resistance of Human NK/T Cell Lymphoma Lines SNK-6 and YTS Cells By Targeting CCL22

Rong Liang, MD PhD, Jian hong Wang, MD, Fang Liu, MD, Xiao hui Duan, MD, Xia Cai Hao, MD, Liang Zhang, MD PhD, Michael Wang, MD, Xiang -xiang Liu, MD, Yan Hua Guo, MD, Zhe Wang, PhD, Hailong Tang, PhD, Ljie Yang, MD

Blood (2018) 132 (Supplement 1): 5302.

https://doi.org/10.1182/blood-2018-99-114405

Published: 2018

Journal Articles

CPSF1-Mediated Acute Myeloid Leukemia Fusion 3'UTR Alternation Is a Potential Therapeutic Target

Takahiro Shima, MD PhD, Amanda G Davis, Daniel T Johnson, Yu Kochi, MD, Sayuri Miyauchi, DDS, PhD, Samuel A Stoner, Junichiro Yuda, MD, Toshihiro Miyamoto, MD PhD, Jie-Hua Zhou, MD, Edward D. Ball, MD, Koichi Akashi, MD PhD, Dong-Er Zhang, PhD

Blood (2018) 132 (Supplement 1): 885.

https://doi.org/10.1182/blood-2018-99-119199

Published: 2018

Journal Articles

Pharmacological Inhibition of Nlk (Nemo-like Kinase) Rescues Erythropoietic Defects in Pre-Clinical Models of Diamond Blackfan Anemia

Mark C Wilkes, Jun Chen, MD PhD, Kavitha Siva, PhD, Gianluca Veretti, PhD, Daniel P. Dever, PhD, Minyoung Youn, PhD, Hee-Don Chae, PhD, Jacqueline D Mercado, Mallika Saxena, Anupama Narla, MD, Bertil Glader, MD, Matthew Porteus, MD PhD, Claire E Repellin, PhD, Hanna T Gazda, MD PhD, Manuel Serrano, PhD, Johan Flygare, MD PhD, Kathleen M. Sakamoto, MD PhD

Blood (2018) 132 (Supplement 1): 754.

https://doi.org/10.1182/blood-2018-99-119954

Published: 2018

NARROW

Alternative Splicing and Intronic Polyadenylation Post-Transcriptionally Regulate CSF3R Via a Cryptic Exon

A Signature of Differentially Expressed Micrornas in Lymphoblastoid Cells from Shwachman-Diamond Syndrome Patients Indicates Possible Molecular Targets for Mirna Therapeutics

Somatic Mutations and Loss of Heterozygosity of HLA Genes Are Frequently Occurred and Tightly Associated with Poor Prognosis in Adult T Cell Leukemia-Lymphoma

The Metabolic Enzyme Hexokinase 2 Localizes to the Nucleus in AML and Normal Hematopoietic Stem/Progenitor Cells to Maintain Stemness

shRNA-Interleukin-6 Modified CD19-Specific Chimeric Antigen Receptor T Cell Significantly Improves the Safety in Acute Lymphoblastic Leukemia

Mutation Profile of PPM1D and TP53 in Patients with Myelodysplastic Syndromes and Complex Chromosome Abnormalities

Genome Data Allow in silico Pharmacogenetic Studies Using the Genetic Makeup of Both the Individual Patient As Well As the Disease

Addiction of B Cell Lymphomas to microRNA-17-92 Is Mediated By a Single Target Gene

Lineage Tracing in Chronic Lymphocytic Leukemia Reveals Clones with Stable Gene Expression States That Differentially Respond to Therapy

Treosulfan Metabolite (S, S-EBDM) Pharmacokinetics Influences Regimen Related Toxicity in Patients with Beta Thalassaemia Major Undergoing HSCT

CRISPR-Cas9 Screen Identifies Me2 , a Mitochondrial Malic Enzyme, As a Molecule Relevant for MCL1 Inhibitor Resistance in AML

Single Nucleotide Polymorphisms in SAR1A Codon Regions Associated with Hydroxyurea Response in Sickle Cell Disease and Potentially Influenced in Mirnas Binding

Interleukin-15 (IL-5) in Combination with Avelumab in Relapsed/Refractory Mature T-Cell Malignancies

Downregulation of MDM2 Leads to Anti-Proliferative Effects through Activation of p53-Associated Pathway Mediated By Both Dual Inhibitor MX69 and Mir-548c-3p in Multiple Myeloma

IRF4 Is Reciprocally Dysregulated Via NF-Κb-Dependent Expression and Loss-of-Function Mutations in Multiple Myeloma

Proof of Concept for Tipifarnib in Relapsed or Refractory Angioimmunoblastic T-Cell Lymphoma (AITL) and CXCL12+ Peripheral T-Cell Lymphoma (PTCL): Preliminary Results from an Open-Label, Phase 2 Study

FIP1L1 Regulates Alternative Polyadenylation of Leukemia-Associated Genes in Acute Myeloid Leukemia

Research of miR-30b in Cisplatin Resistance of Human NK/T Cell Lymphoma Lines SNK-6 and YTS Cells By Targeting CCL22

CPSF1-Mediated Acute Myeloid Leukemia Fusion 3'UTR Alternation Is a Potential Therapeutic Target

Pharmacological Inhibition of Nlk (Nemo-like Kinase) Rescues Erythropoietic Defects in Pre-Clinical Models of Diamond Blackfan Anemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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