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Journal Articles

Cryo-Electron Microscopy Structure of the aIIbβ3-Abciximab Complex

Dragana Nesic, PhD, Yixiao Zhang, PhD, Aleksandar Spasic, PhD, Jihong Li, MD, Davide Provasi, PhD, Marta Filizola, PhD, Thomas Walz, PhD, Barry S. Coller, MD

Blood (2019) 134 (Supplement_1): 3617.

https://doi.org/10.1182/blood-2019-126985

Published: 2019

Journal Articles

Fibrinolysis of Contracted Blood Clots Depends on Whether Plasminogen Activator Acts from inside or Outside

Valerie Tutwiler, PhD, Alina D. Peshkova, MS, Giang Le Minh, Sergei Zaitsev, Rustem I. Litvinov, Douglas B. Cines, MD, John W. Weisel, PhD

Blood (2018) 132 (Supplement 1): 3773.

https://doi.org/10.1182/blood-2018-99-119659

Published: 2018

Journal Articles

The Interaction of Cross-Linked Fibrin Fragment D-Dimer with αIIbβ3 Requires Receptor Activation, Occurs at Sites Other Than the γ-404-411 Sequence, and Contributes to Clot Retraction

Hina Zafar, MS, Jihong Li, MD, Claudia Buitrago, PhD, Dragana Nesic, PhD, Barry S. Coller, MD

Blood (2018) 132 (Supplement 1): 870.

https://doi.org/10.1182/blood-2018-99-116871

Published: 2018

Journal Articles

Pharmacokinetic (PK) and Pharmacodynamic (PD) Studies of RUC-4 Succinate, a Novel αIIbβ3 Pure Antagonist for First Point of Contact Treatment of ST Segment Elevated Myocardial Infarction (STEMI)

Spandana Vootukuri, MS, Jihong Li, MD, Mark Nedelman, MS, MBA, Mariana Babayeva, MD, PhD, Barry S. Coller, MD

Blood (2018) 132 (Supplement 1): 1243.

https://doi.org/10.1182/blood-2018-99-112233

Published: 2018

Journal Articles

Targeting β3 Integrin Psi Domain Inhibits Both Platelet Aggregation and Blood Coagulation: Two Birds with One Stone

Tyler W. Stratton, MSc, Guangheng Zhu, MD, Yiming Wang, MD PhD, Pingguo Chen, PhD, Miguel A. D. Neves, PhD MSc, Reid C. Gallant, MSc, Peter A. A. Norris, BSc, John J. Freedman, MD, Heyu Ni, MD MSc, PhD

Blood (2018) 132 (Supplement 1): 1246.

https://doi.org/10.1182/blood-2018-99-119964

Published: 2018

Journal Articles

Brain-Derived Neurotrophic Factor Induces Platelet Aggregation

Rahma Boulahya, PhD, Audrey Béliveau, BSc, Asmaa Harim, Fabio Luiz Bandeira Ferreira, BPharm, MSc, Jean-François Tanguay, MD, Yahye Merhi, PhD, Marie Lordkipanidzé, BPharm, PhD

Blood (2017) 130 (Supplement 1): 3612.

https://doi.org/10.1182/blood.V130.Suppl_1.3612.3612

Published: 2017

Journal Articles

Reducing Fibrinogen through Platelet Additive Solutions Improves Mitochondrial Function and Reduces Reactive Oxygen Species in Stored Platelets

James A Bynum, PhD, Kristin Reddoch, PhD, Grantham C. Peltier, MS, Ashley S. Taylor, BA, Robbie Montgomery, MS, Michael Adam Meledeo, PhD, Andrew P Cap, MDPhD

Blood (2016) 128 (22): 1357.

https://doi.org/10.1182/blood.V128.22.1357.1357

Published: 2016

Journal Articles

TLR2-PI3K/Akt Signaling Pathway Involved in Platelet Activation Induced By Group B Streptococci

Liping Ma, MD, Xiaoyan Liu, MD, Hongyun Liu, MD, Shuangfeng Xie, PhD, Yanmin Gao, MD, Ping Zhang, Zhang Guoyang

Blood (2015) 126 (23): 4635.

https://doi.org/10.1182/blood.V126.23.4635.4635

Published: 2015

Journal Articles

The Platelet Integrin alphaIIbbeta3 Differentially Interacts with Fibrin and Fibrinogen

Rustem I. Litvinov, PhD, David H. Farrell, PhD, John W. Weisel, PhD, Joel S. Bennett, MD

Blood (2015) 126 (23): 3444.

https://doi.org/10.1182/blood.V126.23.3444.3444

Published: 2015

Journal Articles

Shear-Dependent Fibrillogenesis of Fibronectin: Impact of Platelet Integrins and Actin Cytoskeleton

Huong T. T. Nguyen, MSc, Khon C. Huynh, PhD, Volker R. Stoldt, PhD, Rudiger E. Scharf, MD FAHA

Blood (2014) 124 (21): 1443.

https://doi.org/10.1182/blood.V124.21.1443.1443

Published: 2014

Journal Articles

Thrombin-Dependent Incorporation of Von Willebrand Factor into a Fibrin Network

Adam Miszta, PhD, Leonie Pelkmans, Theo Lindhout, PhD, Philip De Groot, Coenraad Hemker, PhD, Johan Heemskerk, PhD, Hilde Kelchtermans, PhD, Bas De Laat, PhD

Blood (2014) 124 (21): 101.

https://doi.org/10.1182/blood.V124.21.101.101

Published: 2014

Journal Articles

Impact of the Leu33Pro Polymorphism of αIIbβ3 on Integrin – Ligand Interaction Under Abnormally High Shear Conditions

Marianna Gyenes, PhD, Volker R. Stoldt, PhD, Khon C. Huynh, PhD, Rudiger E. Scharf, MD FAHA

Blood (2014) 124 (21): 4156.

https://doi.org/10.1182/blood.V124.21.4156.4156

Published: 2014

Journal Articles

Assessment Of a Novel Synthetic Collagen Reagent By Platelet Aggregometry

Walter Jeske, PhD, Vicki Escalante, BS, Jeanine M. Walenga, PhD, Mamdouh Bakhos, MD

Blood (2013) 122 (21): 3645.

https://doi.org/10.1182/blood.V122.21.3645.3645

Published: 2013

Journal Articles

Contribution Of Platelet Integrins and Shear To The Unfolding Of Fibronectin

Huong T. T. Nguyen, MSc, Khon C. Huynh, PhD, Volker R. Stoldt, PhD, Rüdiger E. Scharf, MD, PhD

Blood (2013) 122 (21): 3519.

https://doi.org/10.1182/blood.V122.21.3519.3519

Published: 2013

Journal Articles

Clot-On-A-Chip: A Microfluidic Device To Study Platelet Aggregation and Contractility Under Shear

Lucas Ting, Ph.D., Shirin Feghhi, Ari Karchin, Wes Tooley, Nathan J White, MD, Nathan Sniadecki, Ph.D.

Blood (2013) 122 (21): 2363.

https://doi.org/10.1182/blood.V122.21.2363.2363

Published: 2013

Journal Articles

Impaired Platelet Attack by fibronectin Binding Partner Msb2 of Candida Albicans

Volker R. Stoldt, PhD, Khon C. Huynh, MSci, Rudiger E. Scharf, MD, FAHA

Blood (2012) 120 (21): 3299.

https://doi.org/10.1182/blood.V120.21.3299.3299

Published: 2012

Journal Articles

A Small Molecule Inhibitor of the Gas6/Mer Pathway Inhibits Platelet Activation and Thrombosis with Equal Efficacy to, but Greater Potency Than, iMer, the Novel MerTK Splice Variant

Brian R. Branchford, MD, Luke Law, BS, Susan Sather, BS, Gary Brodsky, PhD, H. Shelton Earp, III, Xiaodong Wang, Stephen Frye, Douglas K. Graham, MD, PhD, Jorge A Di Paola, MD

Blood (2012) 120 (21): 3303.

https://doi.org/10.1182/blood.V120.21.3303.3303

Published: 2012

Journal Articles

The Impact of Shear Stress On the Interaction of Human Platelet Integrin αIIbβ3 with Fibrinogen.

Marianna Gyenes, PhD, Volker R. Stoldt, PhD, Khon C. Huynh, MSci, Rüdiger E. Scharf, MD, PhD

Blood (2012) 120 (21): 2167.

https://doi.org/10.1182/blood.V120.21.2167.2167

Published: 2012

Journal Articles

Characterization of Fibronectin Assembly by Adherent Platelets Under Flow Conditions: Effect of Shear Stress and Role of β3 Integrins

Khon C. Huynh, MSci, Volker R. Stoldt, PhD, Marianna Gyenes, PhD, Rüdiger E. Scharf, MD, PhD

Blood (2012) 120 (21): 5191.

https://doi.org/10.1182/blood.V120.21.5191.5191

Published: 2012

Journal Articles

Structure-Guided Design of A Novel High Affinity Integrin αIIbβ3 Receptor Antagonist (RUC-2) That Displaces Mg 2+ From the β3 MIDAS,

Jieqing Zhu, PhD, Won-Seok Choi, PhD, Joshua G. McCoy, BS, MS, Ana Negri, PhD, Jianghai Zhu, PhD, Sarasija Naini, BS, MS, Jihong Li, MD, Min Shen, PhD, Wenwei Huang, PhD, Craig J. Thomas, PhD, Marta Filizola, PhD, Timothy Springer, PhD, Barry S. Coller, MD

Blood (2011) 118 (21): 3255.

https://doi.org/10.1182/blood.V118.21.3255.3255

Published: 2011

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Cryo-Electron Microscopy Structure of the aIIbβ3-Abciximab Complex

Fibrinolysis of Contracted Blood Clots Depends on Whether Plasminogen Activator Acts from inside or Outside

The Interaction of Cross-Linked Fibrin Fragment D-Dimer with αIIbβ3 Requires Receptor Activation, Occurs at Sites Other Than the γ-404-411 Sequence, and Contributes to Clot Retraction

Pharmacokinetic (PK) and Pharmacodynamic (PD) Studies of RUC-4 Succinate, a Novel αIIbβ3 Pure Antagonist for First Point of Contact Treatment of ST Segment Elevated Myocardial Infarction (STEMI)

Targeting β3 Integrin Psi Domain Inhibits Both Platelet Aggregation and Blood Coagulation: Two Birds with One Stone

Brain-Derived Neurotrophic Factor Induces Platelet Aggregation

Reducing Fibrinogen through Platelet Additive Solutions Improves Mitochondrial Function and Reduces Reactive Oxygen Species in Stored Platelets

TLR2-PI3K/Akt Signaling Pathway Involved in Platelet Activation Induced By Group B Streptococci

The Platelet Integrin alphaIIbbeta3 Differentially Interacts with Fibrin and Fibrinogen

Shear-Dependent Fibrillogenesis of Fibronectin: Impact of Platelet Integrins and Actin Cytoskeleton

Thrombin-Dependent Incorporation of Von Willebrand Factor into a Fibrin Network

Impact of the Leu33Pro Polymorphism of αIIbβ3 on Integrin – Ligand Interaction Under Abnormally High Shear Conditions

Assessment Of a Novel Synthetic Collagen Reagent By Platelet Aggregometry

Contribution Of Platelet Integrins and Shear To The Unfolding Of Fibronectin

Clot-On-A-Chip: A Microfluidic Device To Study Platelet Aggregation and Contractility Under Shear

Impaired Platelet Attack by fibronectin Binding Partner Msb2 of Candida Albicans

A Small Molecule Inhibitor of the Gas6/Mer Pathway Inhibits Platelet Activation and Thrombosis with Equal Efficacy to, but Greater Potency Than, iMer, the Novel MerTK Splice Variant

The Impact of Shear Stress On the Interaction of Human Platelet Integrin αIIbβ3 with Fibrinogen.

Characterization of Fibronectin Assembly by Adherent Platelets Under Flow Conditions: Effect of Shear Stress and Role of β3 Integrins

Structure-Guided Design of A Novel High Affinity Integrin αIIbβ3 Receptor Antagonist (RUC-2) That Displaces Mg 2+ From the β3 MIDAS,

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