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Journal Articles

Identification of Genetic Vulnerabilities and Synthetic-Lethal Targets in NSD2-High Multiple Myeloma

Amin Sobh, PhD, Charlotte Kaestner, Alberto Riva, PhD, Jonathan D. Licht, MD

Blood (2019) 134 (Supplement_1): 3757.

https://doi.org/10.1182/blood-2019-125951

Published: 2019

Journal Articles

Adenylate Kinase 2 Links Energy Metabolism and Cell Fate in Hematopoietic Stem and Progenitor Cells

Wenqing Wang, PhD, Avni Awani, PhD, Andrew Devilbiss, PhD, Thomas Mathews, PhD, Daniel Thomas, MD PhD, Daniel P. Dever, PhD, Matthew Porteus, MD PhD, Sean Morrison, PhD, Katja G Weinacht, MD PhD

Blood (2019) 134 (Supplement_1): 3705.

https://doi.org/10.1182/blood-2019-129424

Published: 2019

Journal Articles

An Engineered Cell-Traceable Model of Reticular Dysgenesis in Human Hematopoietic Stem Cells Linking Metabolism and Differentiation

Wenqing Wang, PhD, Avni Awani, PhD, Lauren Reich, Yusuke Nakauchi, MD PhD, Daniel Thomas, MD PhD, Daniel P. Dever, PhD, Matthew Porteus, MD PhD, Katja G. Weinacht, MD PhD

Blood (2018) 132 (Supplement 1): 2558.

https://doi.org/10.1182/blood-2018-99-117926

Published: 2018

Journal Articles

Exploring the Function of Sestrin/Gator As Novel Regulators of Hematopoiesis

Nina Kurrle, PhD, Frank Schnütgen, PhD, Juliana Heidler, PhD, Ina Poser, PhD, Frank Wempe, PhD, Diego Yepes, PhD, Ilka Wittig, PhD, Thomas Oellerich, MD, Michael A Rieger, PhD, Harald von Melchner, MD PhD, Hubert Serve, MD

Blood (2016) 128 (22): 1484.

https://doi.org/10.1182/blood.V128.22.1484.1484

Published: 2016

Journal Articles

Glutaminase Inhibitor CB-839 Enhances Proteasome Inhibitor Sensitivity in Multiple Myeloma Cells

Ravyn M. Thompson, Leticia Reyes, Brittany Smith, Nathan G. Dolloff, PhD

Blood (2016) 128 (22): 3294.

https://doi.org/10.1182/blood.V128.22.3294.3294

Published: 2016

Journal Articles

Targeting Redox Overcomes Proteasome Inhibitor Resistance in Multiple Myeloma

Nathan G. Dolloff, PhD, Leticia Reyes, Brittany Smith, John Fairbanks Langenheim, PhD, Yefim Manevich

Blood (2015) 126 (23): 1819.

https://doi.org/10.1182/blood.V126.23.1819.1819

Published: 2015

Journal Articles

Linking Oxidative Stress to Cell Fate-Ipsc-Based Disease Modeling Identifies New Therapeutic Target in Reticular Dysgenesis

Katja G. Weinacht, MD PhD

Blood (2014) 124 (21): 227.

https://doi.org/10.1182/blood.V124.21.227.227

Published: 2014

Journal Articles

AK2 Deficiency In Zebrafish Recapitulates Human Reticular Dysgenesis, An Autosomal Recessive Form Of Severe Combined Immunodeficiency

Alberto Rissone, PhD, Jaya Jagadeesh, Karen Simon, Kevin Bishop, Raman B. Sood, PhD, Fabio Candotti, MD

Blood (2013) 122 (21): 2416.

https://doi.org/10.1182/blood.V122.21.2416.2416

Published: 2013

Journal Articles

Small Molecule Activators Of AMPK Block The Glycogen Production Required For Transformation Of Myeloid Leukemia Cells

Haymanti Bhanot, PhD, Mamatha M. Reddy, PhD, Atsushi Nonami, MD, PhD, Ellen L. Weisberg, PhD, Kelly Xing, Sabrina K. Salgia, John M. Asara, PhD, Richard M. Stone, MD, James D. Griffin, MD, Martin Sattler, PhD

Blood (2013) 122 (21): 1479.

https://doi.org/10.1182/blood.V122.21.1479.1479

Published: 2013

Journal Articles

Adenylate Kinase 2 Regulates Zebrafish Primitive and Definitive Hematopoiesis

Alberto Rissone, PhD, Jaya Jagadeesh, Simon Karen, Kevin Bishop, Trevor Blake, Raman B. Sood, PhD, Fabio Candotti, MD

Blood (2012) 120 (21): 1208.

https://doi.org/10.1182/blood.V120.21.1208.1208

Published: 2012

Journal Articles

Induced Pluripotent Stem Cells From a Patient with Reticular Dysgenesis Recapitulate Defective Myelopoiesis in-Vitro: A Disease Model to Enhance Our Understanding of a Rare Disease.

Katja G. Weinacht, MD, PhD, Kerstin Felgentreff, MD, Alex Devine, MS, Axel Schambach, MD PhD, Waleed Al-herz, MD, Luigi Daniele Notarangelo, MD

Blood (2012) 120 (21): 2142.

https://doi.org/10.1182/blood.V120.21.2142.2142

Published: 2012

Journal Articles

Characterization of AK2 Gene Function in Zebrafish Hematopoiesis

Alberto F Rissone, Guridevi Jayashree Jagadeesh, MS, Karen Simon, Kevin Bishop, Milton English, Trevor Blake, Robert M Nissen, Raman B. Sood, PhD, Fabio Candotti, MD

Blood (2011) 118 (21): 2185.

https://doi.org/10.1182/blood.V118.21.2185.2185

Published: 2011

Journal Articles

Acadesine Inhibits Proliferation and Induces Apoptosis In Multiple Myeloma Cells, and Synergizes with Standard of Care Antimyeloma Agents

Susana Hernández-García, Mercè de Frias, Clara Campàs, Bruno Paiva, Enrique M. Ocio, Jesús F. San Miguel, Sr., MD, PhD, Atanasio Pandiella, Sr., MD, PhD

Blood (2010) 116 (21): 5023.

https://doi.org/10.1182/blood.V116.21.5023.5023

Published: 2010

Journal Articles

Metformin for Therapeutic Intervention In Acute Myeloid Leukemia

Sarah Scotland, Elizabeth Micklow, Zhu Wang, Helena Boutzen, Christian Récher, MD, Gwenn Danet-Desnoyers, Mary Selak, Martin Carroll, MD, Jean-Emmanuel Sarry

Blood (2010) 116 (21): 4351.

https://doi.org/10.1182/blood.V116.21.4351.4351

Published: 2010

Journal Articles

Treatment of MCL Cells with Combined Rituximab and Lenalidomide Enhances NK-Mediated Synapse Formation and Cell Killing.

Svetlana Gaidarova, Laura G Corral, Emilia Glezer, Peter H Schafer, Antonia Lopez-Girona

Blood (2009) 114 (22): 1687.

https://doi.org/10.1182/blood.V114.22.1687.1687

Published: 2009

Journal Articles

Human Adenylate Kinase 2 Deficiency Inhibits Hematopoietic Cell Differentiation towards Neutrophil and T Lymphoid Lineages.

Emmanuelle M. Six, PhD, Chantal Lagresle-Peyrou, PhD, Corinne Demerens-deChappedelaine, PhD, Frederic Rieux-Laucat, PhD, Andrea Didati, PhD, Marie-Claude Stolzenberg, Bruno Cassinat, Pharm.D, Christine Chomienne, MD, PhD, Alain Fischer, MD, PhD, Marina Cavazzana-Calvo, MD, PhD

Blood (2009) 114 (22): 78.

https://doi.org/10.1182/blood.V114.22.78.78

Published: 2009

Journal Articles

Proteomic Profiling of Multiple Myeloma Using iTRAQ Labeling Followed by Multidimensional Liquid Chromatography and Tandem Mass Spectrometry.

Dominik Dytfeld, MD, PhD, Malathi Hari, PhD, John Strahler, PhD, Dattatreya Mellacheruvu, Suchitra Subramani, Alexey Nesvizhskii, PhD, Arun Sreekumar, PhD, Andrzej J Jakubowiak, MD, PhD

Blood (2009) 114 (22): 4865.

https://doi.org/10.1182/blood.V114.22.4865.4865

Published: 2009

Journal Articles

mTORC1 Activity Is Independent of PI3K/Akt but Controlled by AMPK in Acute Myeloid Leukemia.

Alexa Samantha Green, Jerome Tamburini, Lise Willems, Nicolas Chapuis, Sophie Park, Valérie Bardet, Marc Foretz, Benoit Viollet, Norbert Ifrah, Francois Dreyfus, Patrick Mayeux, Catherine Lacombe, Didier Bouscary, MD, PhD

Blood (2008) 112 (11): 935.

https://doi.org/10.1182/blood.V112.11.935.935

Published: 2008

Journal Articles

Human Adenylate Kinase 2 Deficiency Causes a Profound Haematopoietic Defect Associated with Sensorineural Deafness

Blood (2008) 112 (11): lba-2.

https://doi.org/10.1182/blood.V112.11.lba-2.lba-2

Published: 2008

Journal Articles

Biomarkers of Vorinostat Resistance in Cutaneous T-Cell Lymphoma.

Chunlei Zhang, MD, PhD, Baoqiang Li, MD, Rakhshandra Talpur, MD, C. Cameron Yin, MD, PhD, Madeleine Duvic, MD

Blood (2007) 110 (11): 1381.

https://doi.org/10.1182/blood.V110.11.1381.1381

Published: 2007

NARROW

Identification of Genetic Vulnerabilities and Synthetic-Lethal Targets in NSD2-High Multiple Myeloma

Adenylate Kinase 2 Links Energy Metabolism and Cell Fate in Hematopoietic Stem and Progenitor Cells

An Engineered Cell-Traceable Model of Reticular Dysgenesis in Human Hematopoietic Stem Cells Linking Metabolism and Differentiation

Exploring the Function of Sestrin/Gator As Novel Regulators of Hematopoiesis

Glutaminase Inhibitor CB-839 Enhances Proteasome Inhibitor Sensitivity in Multiple Myeloma Cells

Targeting Redox Overcomes Proteasome Inhibitor Resistance in Multiple Myeloma

Linking Oxidative Stress to Cell Fate-Ipsc-Based Disease Modeling Identifies New Therapeutic Target in Reticular Dysgenesis

AK2 Deficiency In Zebrafish Recapitulates Human Reticular Dysgenesis, An Autosomal Recessive Form Of Severe Combined Immunodeficiency

Small Molecule Activators Of AMPK Block The Glycogen Production Required For Transformation Of Myeloid Leukemia Cells

Adenylate Kinase 2 Regulates Zebrafish Primitive and Definitive Hematopoiesis

Induced Pluripotent Stem Cells From a Patient with Reticular Dysgenesis Recapitulate Defective Myelopoiesis in-Vitro: A Disease Model to Enhance Our Understanding of a Rare Disease.

Characterization of AK2 Gene Function in Zebrafish Hematopoiesis

Acadesine Inhibits Proliferation and Induces Apoptosis In Multiple Myeloma Cells, and Synergizes with Standard of Care Antimyeloma Agents

Metformin for Therapeutic Intervention In Acute Myeloid Leukemia

Treatment of MCL Cells with Combined Rituximab and Lenalidomide Enhances NK-Mediated Synapse Formation and Cell Killing.

Human Adenylate Kinase 2 Deficiency Inhibits Hematopoietic Cell Differentiation towards Neutrophil and T Lymphoid Lineages.

Proteomic Profiling of Multiple Myeloma Using iTRAQ Labeling Followed by Multidimensional Liquid Chromatography and Tandem Mass Spectrometry.

mTORC1 Activity Is Independent of PI3K/Akt but Controlled by AMPK in Acute Myeloid Leukemia.

Human Adenylate Kinase 2 Deficiency Causes a Profound Haematopoietic Defect Associated with Sensorineural Deafness

Biomarkers of Vorinostat Resistance in Cutaneous T-Cell Lymphoma.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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