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Journal Articles

Discovery of Novel IL3RA (CD123) Isoforms By Long Read Transcriptomics, Heterogeneous Expression Among AML Patient Cohorts and the Implications for Anti-CD123 Therapeutics

Jason G Underwood, PhD BA, Jenny L. Smith, MSc, MD, Lindsey F. Call, B.A., Elizabeth Tseng, PhD, Tiffany A. Hylkema, BS, Rhonda E. Ries, MA, Amanda R. Leonti, MS, Jason E. Farrar, MD, Timothy Junius Triche, Jr., PhD, Soheil Meshinchi, MD PhD

Blood (2019) 134 (Supplement_1): 4658.

https://doi.org/10.1182/blood-2019-131508

Published: 2019

Journal Articles

Acute Lymphoblastic Leukemia with Zinc-Finger Protein 384 (ZNF384)-Related Rearrangements: A Retrospective Analysis from the Ponte Di Legno Childhood ALL Working Group

Blood (2019) 134 (Supplement_1): 652.

https://doi.org/10.1182/blood-2019-123236

Published: 2019

Journal Articles

Antibody Cloning Identifies Pathogenic and Non-Pathogenic Antibodies in Heparin-Induced Thrombocytopenia and Defines the Molecular Signatures That Differentiate the Two Types of Antibodies

Wen Zhu, Yongwei Zheng, PhD, Mei Yu, PhD, Yaling Wu, Jianhui Wei, Nicholas Schneider, Anand Padmanabhan, MD PhD, Richard H. Aster, MD, Demin Wang, PhD, Renren Wen, PhD

Blood (2019) 134 (Supplement_1): 439.

https://doi.org/10.1182/blood-2019-126097

Published: 2019

Journal Articles

High Accuracy, Low-Cost Transcriptional Diagnostic to Transform Lymphoma Care in Low- and Middle-Income Countries

Edward Briercheck, MD, Fabiola Valvert, MD, Elizabeth Solorzano, MSc, Oscar Silva, MD PhD, Maneka Puligandla, MS, Marcos Mauricio Siliézar Tala, MD, Timothy Guyon, MSc, Samuel L. Dixon, BS, Robert Terbrueggen, PhD, Yasodha Natkunam, MD PhD, Kristen E. Stevenson, MS, David M Weinstock

Blood (2019) 134 (Supplement_1): 409.

https://doi.org/10.1182/blood-2019-121397

Published: 2019

Journal Articles

The High Mobility Group A1 Chromatin Regulator Is Required for Pathologic Megakaryocyte Development and Progression to Myelofibrosis in JAK2V617F Murine Models

Alison R. Moliterno, MD, Donna Marie Williams, PhD, Liping Li, MD PhD, Lingling Xian, MD PhD, Li Luo, PhD, Amy S. Duffield, MD PhD, Ophelia Rogers, Jerry L. Spivak, MD, Linda Resar, MD

Blood (2019) 134 (Supplement_1): 472.

https://doi.org/10.1182/blood-2019-131432

Published: 2019

Journal Articles

Revealing the Impact of Recurrent and Rare Structural Variations in Multiple Myeloma

Even H Rustad, MD, Venkata Yellapantula, PhD, Dominik Glodzik, PhD, Gunes Gundem, PhD, Daniel A. Leongamornlert, PhD, Peter J Campbell, Elli Papaemmanuil, PhD, Ola Landgren, MD PhD, Francesco Maura, MD

Blood (2019) 134 (Supplement_1): 576.

https://doi.org/10.1182/blood-2019-126392

Published: 2019

Journal Articles

Detection of Immunoglobulin Heavy Chain Gene Clonality By High-Throughput Sequencing for Minimal Residual Disease Monitoring in Chronic Lymphocytic Leukaemia

Alicia Serrano, Azahara Fuentes, Blanca Ferrer Lores, MDcal Doctor, Veronica Lendinez, Carolina Monzo, Carmen Ivorra, PhD, Macarena Ortiz, MD, María-Dolores García-Malo, MD, Rosa Collado, MD, Maria Jose Lys, Mar Tormo, Maria Jose Terol, Blanca Navarro, MD PhD, Javier F Chaves, PhD

Blood (2019) 134 (Supplement_1): 1747.

https://doi.org/10.1182/blood-2019-129187

Published: 2019

Journal Articles

A Comparison of Droplet Digital PCR and RT-qPCR for BCR-ABL1 Monitoring in Chronic Myeloid Leukemia

Carmen Fava, Paola Berchialla, PhD, Jessica Petiti, PhD, Maria Teresa Bochicchio, Barbara Izzo, PhD, Emilia Giugliano, Emanuela Ottaviani, Santa Errichiello, PhD, Giovanna Rege Cambrin, MD PhD, Claudia Venturi, Luigiana Luciano, Filomena Daraio, Daniele Calistri, Alessandro Martino, Giuseppe Saglio, MD, Giovanni Martinelli, MD, Fabrizio Pane, MD, Daniela Cilloni, MD PhD, Enrico Marco Gottardi

Blood (2019) 134 (Supplement_1): 2092.

https://doi.org/10.1182/blood-2019-125614

Published: 2019

Journal Articles

Two Year Update of Phase II Trial of Pembrolizumab, Lenalidomide and Dexamethasone As Post -Autologous Stem Cell Transplant Consolidation in Patients with High-Risk Multiple Myeloma

Meena Bansal, DO, David S. Siegel, Jaeil Ahn, PhD, Rena Feinman, PhD, David H. Vesole, MD PhD, Joshua R Richter, MD, Andrew L. Pecora, MD, Elli Gourna Paleoudis, PhD, Scott D. Rowley, MD, Michele L. Donato, MD, Robert Korngold, PhD, Palka Anand, RN, BSN, CCRP, Laura McBride, RN, BSN, OCN, Kristin Ivanovski, RN, BSN, CCRP, Noa Biran, MD

Blood (2019) 134 (Supplement_1): 1911.

https://doi.org/10.1182/blood-2019-125155

Published: 2019

Journal Articles

Chromosome 1q Amplification Is Associated with a History of Prior Malignancies Among Patients Newly Diagnosed with Multiple Myeloma

Elizabeth B Lamont, MD MS, MMSc, Andrew J. Yee, MD, Stuart L. Goldberg, MD, Andrew D Norden, MD MPH, MBA

Blood (2019) 134 (Supplement_1): 2193.

https://doi.org/10.1182/blood-2019-125407

Published: 2019

Journal Articles

A Data-Driven Approach to Define Parsimonious Eligibility Criteria in First-Line Clinical Trials for Diffuse Large B-Cell Lymphoma

R. Andrew Harkins, Sharvil Piyush Patel, Michelle J. Lee, MD PhD, Jeffrey M. Switchenko, PhD MS, Christopher R. Flowers, MD MS

Blood (2019) 134 (Supplement_1): 3416.

https://doi.org/10.1182/blood-2019-125779

Published: 2019

Journal Articles

Association between Sensorineural Hearing Loss and Homozygous Sickle Cell Anemia: A Meta-Analysis

Zachary Monroe Kiser, BS, PhD, Kristen A Clark, BA, Jane L Sumner, PhD, Gregory M Vercellotti, MD, M.Dawn Nelson, PhD

Blood (2019) 134 (Supplement_1): 3453.

https://doi.org/10.1182/blood-2019-127740

Published: 2019

Journal Articles

A Phase 2 Open-Label Study of Danicopan (ACH-0144471) in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have an Inadequate Response to Eculizumab Monotherapy

Austin Kulasekararaj, MBBS MDMRCP FRCPath, Antonio M. Risitano, MD PhD, Jaroslaw P. Maciejewski, MD PhD, Rosario Notaro, MD, Peter Browett, BMedSci, MBChB, FRACP, FRCPA, Jong-Wook Lee, MD, Mingjun Huang, PhD, Michael Geffner, MD, Robert A. Brodsky, MD

Blood (2019) 134 (Supplement_1): 3514.

https://doi.org/10.1182/blood-2019-124748

Published: 2019

Journal Articles

Utility of Newborn Screening for Severe Combined Immunodeficiency and X-Linked Agammaglobulinemia Using TREC and KREC Assays

Manabu Wakamatsu, MD, Hideki Muramatsu, MD PhD, Shinsuke Kataoka, MD, Yusuke Okuno, MD PhD, Sakai Yoshimi, Yoko Nakajima, MD PhD, Tetsuya Ito, MD PhD, Ikuya Tsuge, MD PhD, Seiji Kojima, MD PhD, Yoshiyuki Takahashi, MD PhD

Blood (2019) 134 (Supplement_1): 3604.

https://doi.org/10.1182/blood-2019-126669

Published: 2019

Journal Articles

Comparison of Gold Standard Genescan with NGS-Based TCR-Beta Clonality Analysis Using Oncomine TCR Beta-Short Read Assay

Cora Husemann, Karsten Kleo, Timothy Looney, PhD, Chris Allen, Bernhard Josef Woermann, Markus Möbs, Michael Hummel

Blood (2019) 134 (Supplement_1): 4664.

https://doi.org/10.1182/blood-2019-129822

Published: 2019

Journal Articles

Long Range Sequencing Shows Improved Resolution in the Detection of Beta Globin Cluster Variants

Aruna Rangan, MD, Molly S. Hein, Tejaswi Koganti, William G. Jenkinson, Christopher A. Hilker, Joseph H. Blommel, Tavanna R. Porter, MS, LCGC, Jin Jen, Nicole Hoppman, Rong He, MD, David S. Viswanatha, Ross Aleff, James D. Hoyer, MD, Eric Wieben, Eric W. Klee, PhD, Benjamin R. Kipp, Jennifer L. Oliveira, MD

Blood (2019) 134 (Supplement_1): 3548.

https://doi.org/10.1182/blood-2019-130652

Published: 2019

Journal Articles

Potential Genetic and Immunologic Mechanisms of Therapeutic Resistance and Disease Progression in CNS Lymphoma Elucidated Via Whole Brain Autopsy Studies

David A. Solomon, MD, PhD, Huimin Geng, PhD, Raymond A. Sobel, MD, Lakshmi Subbaraj, B.S., Mazie Tsang, MD, James L. Rubenstein, MD PhD

Blood (2019) 134 (Supplement_1): 1494.

https://doi.org/10.1182/blood-2019-131302

Published: 2019

Journal Articles

Genetic Characteristics and Clinical Outcomes of T-Cell Acute Lymphoblastic Leukemia; Myeloid-Suppressive Therapeutic Approach Based on Allogeneic Hematopoietic Cell Transplantation May Benefit in Early T-Cell Precursor Acute Lymphoblastic Leukemia

Jae-Ho Yoon, MD PhD, Han Bi Lee, Gi June Min, MD, Sung-Soo Park, Silvia Park, Byung Sik Cho, MD PhD, Ki-Seong Eom, MD PhD, Yoo-Jin Kim, MD PhD, Hee-Je Kim, MD PhD, Chang-Ki Min, MD PhD, Seok-Goo Cho, MD PhD, Jong Wook Lee, MD PhD, Seok Lee, MD PhD

Blood (2019) 134 (Supplement_1): 1470.

https://doi.org/10.1182/blood-2019-129870

Published: 2019

Journal Articles

Comprehensive Profiling of Disease-Relevant Copy Number Aberrations Improves Risk Assessment and Unveils the Clonal Origin of Relapse in Pediatric Acute Lymphoblastic Leukemia

Donát Alpár, PhD, Richárd Kiss, MD, Ambrus Gángó, MD, Anne Benard-Slagter, PhD, Bálint Egyed, MD, Irén Haltrich, PhD, Lajos Hegyi, MSc, Karel de Groot, PhD, Péter Attila Király, MD PhD, Szilvia Krizsán, MD, Béla Kajtár, MD PhD, Henriett Pikó, PhD, László Pajor, MD PhD DSc, Ágnes Vojcek, MD, András Matolcsy, MD PhD DSc, Gábor Kovács, MD PhD DSc, Károly Szuhai, MD PhD, Suvi Savola, PhD, Csaba Bödör, PhD

Blood (2019) 134 (Supplement_1): 1474.

https://doi.org/10.1182/blood-2019-128699

Published: 2019

Journal Articles

Combining Gene Expression Profiling and Artificial Intelligence to Diagnose B-Cell Non-Hodgkin Lymphoma

Victor Bobée, PharmD, Fanny Drieux, MD, Vinciane Marchand, Vincent Sater, Liana Veresezan, MD, Jean-Michel Picquenot, MD, Pierre-Julien Viailly, Marie-delphine Lanic, Mathieu Viennot, Elodie Bohers, PhD, Lucie Oberic, MD, Christiane Copie-Bergman, MD PhD, Thierry Jo Molina, MD PhD, Philippe Gaulard, MD PhD, Corinne Haioun, MD PhD, Gilles A. Salles, MD PhD, Herve Tilly, MD PhD, Fabrice Jardin, Philippe Ruminy, PhD

Blood (2019) 134 (Supplement_1): 1476.

https://doi.org/10.1182/blood-2019-122405

Published: 2019

NARROW

Discovery of Novel IL3RA (CD123) Isoforms By Long Read Transcriptomics, Heterogeneous Expression Among AML Patient Cohorts and the Implications for Anti-CD123 Therapeutics

Acute Lymphoblastic Leukemia with Zinc-Finger Protein 384 (ZNF384)-Related Rearrangements: A Retrospective Analysis from the Ponte Di Legno Childhood ALL Working Group

Antibody Cloning Identifies Pathogenic and Non-Pathogenic Antibodies in Heparin-Induced Thrombocytopenia and Defines the Molecular Signatures That Differentiate the Two Types of Antibodies

High Accuracy, Low-Cost Transcriptional Diagnostic to Transform Lymphoma Care in Low- and Middle-Income Countries

The High Mobility Group A1 Chromatin Regulator Is Required for Pathologic Megakaryocyte Development and Progression to Myelofibrosis in JAK2V617F Murine Models

Revealing the Impact of Recurrent and Rare Structural Variations in Multiple Myeloma

Detection of Immunoglobulin Heavy Chain Gene Clonality By High-Throughput Sequencing for Minimal Residual Disease Monitoring in Chronic Lymphocytic Leukaemia

A Comparison of Droplet Digital PCR and RT-qPCR for BCR-ABL1 Monitoring in Chronic Myeloid Leukemia

Two Year Update of Phase II Trial of Pembrolizumab, Lenalidomide and Dexamethasone As Post -Autologous Stem Cell Transplant Consolidation in Patients with High-Risk Multiple Myeloma

Chromosome 1q Amplification Is Associated with a History of Prior Malignancies Among Patients Newly Diagnosed with Multiple Myeloma

A Data-Driven Approach to Define Parsimonious Eligibility Criteria in First-Line Clinical Trials for Diffuse Large B-Cell Lymphoma

Association between Sensorineural Hearing Loss and Homozygous Sickle Cell Anemia: A Meta-Analysis

A Phase 2 Open-Label Study of Danicopan (ACH-0144471) in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have an Inadequate Response to Eculizumab Monotherapy

Utility of Newborn Screening for Severe Combined Immunodeficiency and X-Linked Agammaglobulinemia Using TREC and KREC Assays

Comparison of Gold Standard Genescan with NGS-Based TCR-Beta Clonality Analysis Using Oncomine TCR Beta-Short Read Assay

Long Range Sequencing Shows Improved Resolution in the Detection of Beta Globin Cluster Variants

Potential Genetic and Immunologic Mechanisms of Therapeutic Resistance and Disease Progression in CNS Lymphoma Elucidated Via Whole Brain Autopsy Studies

Genetic Characteristics and Clinical Outcomes of T-Cell Acute Lymphoblastic Leukemia; Myeloid-Suppressive Therapeutic Approach Based on Allogeneic Hematopoietic Cell Transplantation May Benefit in Early T-Cell Precursor Acute Lymphoblastic Leukemia

Comprehensive Profiling of Disease-Relevant Copy Number Aberrations Improves Risk Assessment and Unveils the Clonal Origin of Relapse in Pediatric Acute Lymphoblastic Leukemia

Combining Gene Expression Profiling and Artificial Intelligence to Diagnose B-Cell Non-Hodgkin Lymphoma

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American Society of Hematology

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