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Journal Articles

CD70-Specific CAR T Cells Have Potent Activity Against Acute Myeloid Leukemia (AML) without HSC Toxicity

Tim Sauer, MD, Kathan Parikh, Sandhya Sharma, Bilal Omer, MD, Stephen Gottschalk, MD, Cliona M. Rooney, PhD

Blood (2019) 134 (Supplement_1): 1932.

https://doi.org/10.1182/blood-2019-125534

Published: 2019

Journal Articles

Investigation of Cell-Contact Dependent Alterations in Immune Synapse Formation between T Cells and BCP-ALL Cells

Britta Wenske, PhD, Lothar Marischen, PhD, Julia Welzenbach, André Heimbach, PhD, Per Hoffmann, PhD, Selim Corbacioglu, MD, David A Williams, MD, Anja Troeger, MD

Blood (2019) 134 (Supplement_1): 2754.

https://doi.org/10.1182/blood-2019-128835

Published: 2019

Journal Articles

T Cells Expressing an Anti-B-Cell Maturation Antigen (BCMA) Chimeric Antigen Receptor with a Fully-Human Heavy-Chain-Only Antigen Recognition Domain Induce Remissions in Patients with Relapsed Multiple Myeloma

Lekha Mikkilineni, MD, Elisabet E. Manasanch, MD, Norris Lam, BS, Danielle Vanasse, BS, Jennifer N. Brudno, MD, Irina Maric, MD MSci, Jeremy J. Rose, MS, Maryalice Stetler-Stevenson, MD PhD, Hao-Wei Wang, MD PhD, Constance M. Yuan, MD PhD, David F. Stroncek, MD, Jennifer Mann, CRNP, Micaela Ganadan, BSN, RN, Rashmika Patel, Nathan Trinklein, PhD, Ben Buelow, MD PhD, Ronald E. Gress, MD, James N. Kochenderfer, MD

Blood (2019) 134 (Supplement_1): 3230.

https://doi.org/10.1182/blood-2019-129088

Published: 2019

Journal Articles

Ex-Vivo Stimulation with DC/AML Fusion Vaccine in the Presence of Cytokines Leads to an Activated T Cell Memory Phenotype and Enhanced Cytotoxicity with Potential for Use As an Adoptive Cellular Therapy

Jessica Liegel, MD, Dina Stroopinsky, PhD, Lourdes M. Mendez, MD PhD, Malgorzata McMasters, MD, Haider Ghiasuddin, BA, Maryam Rahimian, MD, Myrna Nahas, MD, Matthew Weinstock, MD, Salvia Jain, MD, Marzia Capelletti, PhD MMSc, Lina Bisharat, MA, Adam Morin, BA, Shira Orr, PhD, Jacalyn Rosenblatt, MD, Donald Kufe, MD, David E. Avigan, MD

Blood (2018) 132 (Supplement 1): 2728.

https://doi.org/10.1182/blood-2018-99-119996

Published: 2018

Journal Articles

Adapter Chimeric Antigen Receptor (aCAR)-Engineered NK-92 Cells: An Off-the-Shelf Cellular Therapeutic for Universal Tumor Targeting

Stefan Grote, MSc, Christian M. Seitz, MD, Simon Diepold, cand. MD, Markus Buchner, cand. MD, Caroline Baden, Elke Malenke, Sophie Marie Dieckmann, Hanna Schwaemmle, Joerg Mittelstaet, PhD, Andrew Kaiser, PhD, Patrick Schlegel, MD, Rupert Handgretinger, MD PhD, Sabine Schleicher, PhD

Blood (2018) 132 (Supplement 1): 3331.

https://doi.org/10.1182/blood-2018-99-116724

Published: 2018

Journal Articles

CD38 Specific Chimeric Antigen Receptor KHYG-1 Natural Killer Cells: A Potential "Off the Shelf" Therapy for Multiple Myeloma

Arwen Stikvoort, PhD, Subhashis Sarkar, PhD, Renée Poels, BSc, Niels WCJ van de Donk, MD PhD, Sonja Zweegman, MD PhD, Michael E O'Dwyer, MD, Tuna Mutis, PhD

Blood (2018) 132 (Supplement 1): 3261.

https://doi.org/10.1182/blood-2018-99-116403

Published: 2018

Journal Articles

Low Levels of Neurologic Toxicity with Retained Anti-Lymphoma Activity in a Phase I Clinical Trial of T Cells Expressing a Novel Anti-CD19 CAR

Jennifer Brudno, MD, Steven Hartman, Norris Lam, BS, David F. Stroncek, John M. Rossi, MS, Yueh-wei Shen, Allen Xue, PhD, Adrian Bot, MD PhD, Jennifer A Kanakry, MD, Steven Z. Pavletic, MD, Lekha Mikkilineni, MD, Mark Roschewski, MD, Robert M. Dean, MD, Jeremy J. Rose, MS, Rashmika Patel, Brenna Hansen, Steve A. Rosenberg, Ronald E. Gress, MD, James N. Kochenderfer, MD

Blood (2018) 132 (Supplement 1): 697.

https://doi.org/10.1182/blood-2018-99-113731

Published: 2018

Journal Articles

Genomic and Immune Profiles of Multiple Myeloma Revealed By Whole Genome and Transcriptome Sequencing

Christopher J. Yoon, MPhil, Hyojin Song, Seulki Song, Hyejoo Park, Dong-Yeop Shin, MD PhD, Junshik Hong, MD, Inho Kim, MD PhD, Hyun Jung Lee, MD, Byung-Su Kim, MD PhD, Jung Lim Lee, MD, Sung-Soo Yoon, MD PhD, Young Seok Ju, Youngil Koh, MD PhD

Blood (2018) 132 (Supplement 1): 4493.

https://doi.org/10.1182/blood-2018-99-117546

Published: 2018

Journal Articles

Combinatorial Targeting of Multiple Shared Antigens By Adapter-CAR-T Cells (aCAR-Ts) Allows Target Cell Discrimination and Specific Lysis Based on Differential Expression Profiles

Christian M. Seitz, MD, Verena Kieble, cand.MD, Clara Illi, cand. MD, Selina Reiter, cand. MD, Stefan Grote, MSc, Joerg Mittelstaet, PhD, Dominik Lock, M.Sc., Andrew Kaiser, PhD, Sabine Schleicher, PhD, Rupert Handgretinger, MD PhD, Peter Lang, MD, Patrick Schlegel, MD

Blood (2018) 132 (Supplement 1): 4543.

https://doi.org/10.1182/blood-2018-99-115630

Published: 2018

Journal Articles

Development and Evaluation of CART Targeting Bcma with Humanized Alpaca-Derived Single-Domain Antibody As Antigen Recognition Domain

Lu Han, MS, Quanli Gao, MD, Keshu Zhou, MD, Qingsong Yin, PhD, Baijun Fang, MD, Jian Zhou, MD PhD, Xinghu Zhu, MD, Delong Liu, MD PhD, Jishuai Zhang, PhD, Haoyue Du, Hongjian Li, MS, Yongping Song, MD

Blood (2018) 132 (Supplement 1): 1976.

https://doi.org/10.1182/blood-2018-99-114980

Published: 2018

Journal Articles

Bioengineered Autologous Dendritic Cells Enhance CAR T Cell Cytotoxicity By Providing Cytokine Stimulation and Intratumoral Dendritic Cells

Hyung C Suh, MD PhD, Katherine A. Pohl, B.S., Christina Termini, PhD BS, Jenny Kan, BS, John M. Timmerman, MD, Dennis J. Slamon, MD PhD, John P Chute, MD

Blood (2018) 132 (Supplement 1): 3693.

https://doi.org/10.1182/blood-2018-99-115296

Published: 2018

Journal Articles

T Cells Expressing Anti-B-Cell Maturation Antigen (BCMA) Chimeric Antigen Receptors with Antigen Recognition Domains Made up of Only Single Human Heavy Chain Variable Domains Specifically Recognize Bcma and Eradicate Tumors in Mice

Norris Lam, BS, Leah Alabanza, PhD, Nathan Trinklein, PhD, Ben Buelow, MD PhD, James N. Kochenderfer, MD

Blood (2017) 130 (Supplement 1): 504.

https://doi.org/10.1182/blood.V130.Suppl_1.504.504

Published: 2017

Journal Articles

Defining the Diversity and Specificity of Neoantigen-Specific T Cells in Chronic Lymphocytic Leukemia

Zhuting Hu, PhD, Jing Sun, PhD, Jintaek Kim, PhD, Annabelle Jacinta Anandappa, BS, Donna Leet, BA, Louise Williams, PhD, David J Bozym, PhD, Christina Chen, BS, Wandi Zhang, MD, Diana Tabbaa, BS, Pavan Bachireddy, MD, Sachet Shukla, PhD, Scott Steelman, PhD, Derin Keskin, PhD, Catherine J. Wu, MD

Blood (2017) 130 (Supplement 1): 386.

https://doi.org/10.1182/blood.V130.Suppl_1.386.386

Published: 2017

Journal Articles

Targeting T-Cell Malignancies with Chimeric Antigen Receptors Using Two Structurally Different Antigen Binding Domains Against CD5

Sunil S Raikar, MD, Lauren C Fleischer, Robert Moot, B.S., Na Yoon Paik, B.S., Kristopher Knight, B.S., Christopher B Doering, PhD, H. Trent Spencer, PhD

Blood (2017) 130 (Supplement 1): 4462.

https://doi.org/10.1182/blood.V130.Suppl_1.4462.4462

Published: 2017

Journal Articles

A Drug-Regulated CAR Platform (DARIC) Induces Effective and Reversible Tumor Control In Vivo Using Non-Immunosuppressive Rapamycin Dosing

Wai-Hang Leung, PhD, Michael T Certo, PhD, Holly M. Horton, PhD, Joel Gay, Tracy VandenBerg, Jordan Jarjour, PhD, Alexander Astrakhan, PhD

Blood (2017) 130 (Supplement 1): 1910.

https://doi.org/10.1182/blood.V130.Suppl_1.1910.1910

Published: 2017

Journal Articles

Novel Adapter Chimeric Antigen Receptor (aCAR) T Cells for Temporally Controllable Targeting of Single and Multiple Tumor Antigens

Christian M. Seitz, MD, Patrick Schlegel, MD, Jana Hau, Ann-Christin Krahl, Sarah Schroeder, Giulia Bender, Selina Reiter, Sabine Schleicher, PhD, Karin Schilbach, PhD, Martin Ebinger, MD, Philipp Knopf, MSc, Manfred Kneilling, MD, Bernd J. Pichler, PhD, Joerg Mittelstaet, PhD, Dominik Lock, MSc, Andrew Kaiser, PhD, Peter J. Lang, MD, Rupert Handgretinger, MD

Blood (2017) 130 (Supplement 1): 1912.

https://doi.org/10.1182/blood.V130.Suppl_1.1912.1912

Published: 2017

Journal Articles

Engineering CD5-Targeted Chimeric Antigen Receptors and Edited T Cells for the Treatment of T-Cell Leukemia

Lauren C Fleischer, Sunil S Raikar, MD, Robert Moot, B.S., Kristopher A Knight, B.S., Christopher B Doering, PhD, H. Trent Spencer, PhD

Blood (2017) 130 (Supplement 1): 1914.

https://doi.org/10.1182/blood.V130.Suppl_1.1914.1914

Published: 2017

Journal Articles

Generation of FVIII-Specific Tregs Expressing a Chimeric Antigen Receptor (CAR) to Suppress Inhibitor Development in Hemophilia a Mice

Moanaro Biswas, PhD, Todd M Brusko, PhD, Roland W Herzog, PhD

Blood (2017) 130 (Supplement 1): 176.

https://doi.org/10.1182/blood.V130.Suppl_1.176.176

Published: 2017

Journal Articles

A Novel NKp44-Based Chimeric Antigen Receptor That Targets Multiple Types of Cancer

Yasushi Kasahara, MD, Changsu Shin, MD, Sakiko Yoshida, MD PhD, Takayuki Takachi, MD PhD, Nobuhiro Kubo, MD, Haruko Iwabuchi, MD PhD, Masaru Imamura, MD PhD, Akihiko Saitoh, MD PhD, Chihaya Imai, MD PhD

Blood (2016) 128 (22): 3517.

https://doi.org/10.1182/blood.V128.22.3517.3517

Published: 2016

Journal Articles

In Vitro Co-Culture of CLL-B Cells Reveals Long-Term Survival, Proliferation, and Maintenance of Telomere Length

Ceri H Jones, MBBCh, Thet Thet Lin, PhD, Elisabeth Jane Walsby, PhD, Guy E Pratt, MDFRCP FRCPath, Christopher Fegan, Duncan M Baird, PhD, Chris Pepper, PhD

Blood (2016) 128 (22): 350.

https://doi.org/10.1182/blood.V128.22.350.350

Published: 2016

NARROW

CD70-Specific CAR T Cells Have Potent Activity Against Acute Myeloid Leukemia (AML) without HSC Toxicity

Investigation of Cell-Contact Dependent Alterations in Immune Synapse Formation between T Cells and BCP-ALL Cells

T Cells Expressing an Anti-B-Cell Maturation Antigen (BCMA) Chimeric Antigen Receptor with a Fully-Human Heavy-Chain-Only Antigen Recognition Domain Induce Remissions in Patients with Relapsed Multiple Myeloma

Ex-Vivo Stimulation with DC/AML Fusion Vaccine in the Presence of Cytokines Leads to an Activated T Cell Memory Phenotype and Enhanced Cytotoxicity with Potential for Use As an Adoptive Cellular Therapy

Adapter Chimeric Antigen Receptor (aCAR)-Engineered NK-92 Cells: An Off-the-Shelf Cellular Therapeutic for Universal Tumor Targeting

CD38 Specific Chimeric Antigen Receptor KHYG-1 Natural Killer Cells: A Potential "Off the Shelf" Therapy for Multiple Myeloma

Low Levels of Neurologic Toxicity with Retained Anti-Lymphoma Activity in a Phase I Clinical Trial of T Cells Expressing a Novel Anti-CD19 CAR

Genomic and Immune Profiles of Multiple Myeloma Revealed By Whole Genome and Transcriptome Sequencing

Combinatorial Targeting of Multiple Shared Antigens By Adapter-CAR-T Cells (aCAR-Ts) Allows Target Cell Discrimination and Specific Lysis Based on Differential Expression Profiles

Development and Evaluation of CART Targeting Bcma with Humanized Alpaca-Derived Single-Domain Antibody As Antigen Recognition Domain

Bioengineered Autologous Dendritic Cells Enhance CAR T Cell Cytotoxicity By Providing Cytokine Stimulation and Intratumoral Dendritic Cells

T Cells Expressing Anti-B-Cell Maturation Antigen (BCMA) Chimeric Antigen Receptors with Antigen Recognition Domains Made up of Only Single Human Heavy Chain Variable Domains Specifically Recognize Bcma and Eradicate Tumors in Mice

Defining the Diversity and Specificity of Neoantigen-Specific T Cells in Chronic Lymphocytic Leukemia

Targeting T-Cell Malignancies with Chimeric Antigen Receptors Using Two Structurally Different Antigen Binding Domains Against CD5

A Drug-Regulated CAR Platform (DARIC) Induces Effective and Reversible Tumor Control In Vivo Using Non-Immunosuppressive Rapamycin Dosing

Novel Adapter Chimeric Antigen Receptor (aCAR) T Cells for Temporally Controllable Targeting of Single and Multiple Tumor Antigens

Engineering CD5-Targeted Chimeric Antigen Receptors and Edited T Cells for the Treatment of T-Cell Leukemia

Generation of FVIII-Specific Tregs Expressing a Chimeric Antigen Receptor (CAR) to Suppress Inhibitor Development in Hemophilia a Mice

A Novel NKp44-Based Chimeric Antigen Receptor That Targets Multiple Types of Cancer

In Vitro Co-Culture of CLL-B Cells Reveals Long-Term Survival, Proliferation, and Maintenance of Telomere Length

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American Society of Hematology

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ASH Publications

American Society of Hematology

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