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Journal Articles

Metabolic engineering against the arginine microenvironment enhances CAR-T cell proliferation and therapeutic activity

Brief Report
Livingstone Fultang, Sarah Booth, Orli Yogev, Barbara Martins da Costa, Vanessa Tubb, Silvia Panetti, Victoria Stavrou, Ugo Scarpa, Andris Jankevics, Gavin Lloyd, Andrew Southam, Steven P. Lee, Warwick B. Dunn, Louis Chesler, Francis Mussai, Carmela De Santo
Journal: Blood
Blood (2020) 136 (10): 1155–1160.
https://doi.org/10.1182/blood.2019004500
Published: 2020
Includes: Supplemental data
Journal Articles

Arginine Depletion in Combination with Canavanine Supplementation Induces Massive Cell Death in Myeloma Cells By Interfering with Their Protein Metabolism and Bypassing Potential Rescue Mechanisms

Johannes Windschmitt, Björn Jacobi, MD, Yagmur Bülbül, Lilli Sester, Janine Tappe, Christof Hiebel, PhD, Christian Behl, PhD, Matthias Theobald, Markus Munder, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3205.
https://doi.org/10.1182/blood-2018-99-113396
Published: 2018
Journal Articles

Arginine Deprivation With Pegylated Arginine Deiminase Induces Death Of Acute Myeloid Leukaemia Cells In Vivo

Farideh Miraki-Moud, PhD, Linda Ariza-McNaughton, MSc, Essam A Ghazaly, MD, Katharine A Hodby, Phuong Luong, Andrew Clear, PhD, Fareeda Sohrabi, John Bomalaski, John Gribben, MD, DSc, Dominique Bonnet, PhD, Peter Szlosarek, David C Taussig, PhD, MRCP, FRCPath
Journal: Blood
Blood (2013) 122 (21): 1458.
https://doi.org/10.1182/blood.V122.21.1458.1458
Published: 2013
Journal Articles

ATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia

Clinical Trials & Observations
Julie Rousseau, Vincent Gagné, Malgorzata Labuda, Cyrielle Beaubois, Daniel Sinnett, Caroline Laverdière, Albert Moghrabi, Stephen E. Sallan, Lewis B. Silverman, Donna Neuberg, Jeffery L. Kutok, Maja Krajinovic
Journal: Blood
Blood (2011) 118 (22): 5883–5890.
https://doi.org/10.1182/blood-2011-05-355560
Published: 2011
Includes: Supplemental data
Journal Articles

Identification of Chemotherapy-Resistant Mechanisms in Childhood T-ALL Cell Lines: Correlation with Genetic Profiles in Patients Having Early Treatment Failure.

David A. Estes, BS, Debbie M. Lovato, BS, Hadya M. Khawaja, MS, Stuart S. Winter, MD, Richard S. Larson, MD,PhD
Journal: Blood
Blood (2006) 108 (11): 4376.
https://doi.org/10.1182/blood.V108.11.4376.4376
Published: 2006
Journal Articles

Establishment and Indentification of Genetic Alterations in Chemotherapy-Resistant T-ALL Cell Lines.

David A. Estes, BS, Rahul Poria, MS, Debbie M. Lovato, BS, Hadya M. Khawaja, MS, Claudia L. Quan, Stuart S. Winter, MD, Richard S. Larson, MD/PhD
Journal: Blood
Blood (2005) 106 (11): 4423.
https://doi.org/10.1182/blood.V106.11.4423.4423
Published: 2005