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Journal Articles

AT1412, a Patient-Derived Antibody in Development for the Treatment of CD9 Positive Precursor B-Acute Lymphoblastic Leukemia

Free
Greta De Jong, Sophie E Levie, Remko Schotte, PhD, Wouter Pos, PhD, Daniel Go, Etsuko Yasuda, Madalina Cercel, Susan E van Hal-van Veen, Esmay Frankin, Anikó Szabó, MD, Julien Villaudy, PhD, Pauline M van Helden, PhD, Hans van Eenennaam, PhD, Hergen Spits, PhD, Anita W Rijneveld, MD PhD, Mette D Hazenberg, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4461.
https://doi.org/10.1182/blood-2019-127894
Published: 2019
Journal Articles

T Cell Determinants of Response and Resistance to PD-1 Blockade in Richter's Transformation

Free
Erin Parry, MD PhD, Camilla K Lemvigh, MSc, Annabelle J Anandappa, MD, Shuqiang Li, PhD, Lillian Werner, MS, Ana Lako, Noelia Purroy, MD PhD, Satyen H Gohil, PhD, M.B.,B.S., Giacomo Oliveira, PhD, Pavan Bachireddy, MD, Teddy Huang, Ignaty Leshchiner, PhD, Aina Zurita Martinez, Lars Ronn Olsen, PhD, Kenneth Livak, PhD, Gad Getz, PhD, Donna S Neuberg, ScD, Scott J Rodig, MD PhD, William G. Wierda, MD PhD, Peter Kharchenko, PhD, Nitin Jain, MD, Catherine J. Wu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 680.
https://doi.org/10.1182/blood-2019-125904
Published: 2019
Journal Articles

Anti-Leukemic Activity of Single Agent Venetoclax in Newly Diagnosed Acute Myeloid Leukemia: A Sub-Set Analysis of the Caveat Study

Free
Chong Chyn Chua, MBBS, John Reynolds, PhD, Jessica M Salmon, PhD, Chun Fong, Stephen B Ting, MB BS, FRACP, FRCPA, PhD, Ing Soo Tiong, MBBS,FRACP,FRCPA, Shaun Fleming, MBBS,, Sarah MacRaild, Donia M Moujalled, PhD, Giovanna Pomilio, Nik Cummings, Julie McManus, Adam Ivey, BSc, MSc, PhD, Purvi M Kakadia, PhD, Stefan K. Bohlander, MD, Andrew W. Roberts, MBBS, PhD FRACP, FRCPA, Andrew H. Wei, PhD FRACP, FRCPA, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 462.
https://doi.org/10.1182/blood-2019-126640
Published: 2019
Journal Articles

Overall Survival in Patients with JAK2 and ASXL1 Positive Myeloproliferative Neoplasms

Free
Murtadha Al-Khabori, MD, Shoaib Al-Zadjali, PhD, Iman Al Noumani, Khalil Al Farsi, Salam Al-Kindi, MD, Mohamed Al Huneini, MD, Naglaa Fawaz, MBBChir, MMSc, PhD, Al Lamki Sulayma, MD, Mahdiya Pir Al Bulushi, MD FRCPC, Khalid Al Hashmi, MD, Muna Al Tarshi, MD, Muhanna Almusalhi
Journal: Blood
Blood (2019) 134 (Supplement_1): 5383.
https://doi.org/10.1182/blood-2019-128309
Published: 2019
Journal Articles

Loss of Heterozygosity in the Short Tandem Repeat (STR) Loci Found in Tumor DNA of De Novo Diagnosed ALL Patients As a Factor Predicting Poor Outcome

Free
Natalya V Risinskaya, PhD, Olga A. Gavrilina, MD PhD, Julia A. Chabaeva, Anna Yushkova, Andrey B Sudarikov, PhD DSc, Sergei M. Kulikov, PhD, Elena N. Parovichnikova, MD PhD, Valery G. Savchenko, MD PhD academician
Journal: Blood
Blood (2019) 134 (Supplement_1): 5204.
https://doi.org/10.1182/blood-2019-126668
Published: 2019
Journal Articles

Next Generation Sequencing and Microrna Assay in a Cohort of Patients Affected By Myelodysplastic Syndromes. an Analysis of Clinical and Genotypic Features

Free
Daniele Avenoso, MD, Margherita Squillario, Annalisa Barla, Alessandro Verri, Enrico Carminati, Clara Nurra, Elisabetta Todisco, MD PhD, Federica Gigli, MD, Giuliana Gregato, Claudia Poletti, Francesco Bertolini, MD PhD, Ghulam J. Mufti, MBBS, FRCP, FRCPath, DM, Mili Shah, FRCPath, Maurizio Miglino
Journal: Blood
Blood (2019) 134 (Supplement_1): 5414.
https://doi.org/10.1182/blood-2019-130153
Published: 2019
Journal Articles

Clonal Cytopenias of Undetermined Significance Are Common in Cytopenic Adults Evaluated for MDS in the National MDS Study

Free
Johannes B Goll, MS, R. Coleman Lindsley, MD PhD, William F. Hooper, MS, Rafael Bejar, MD PhD, Jason Walker, Robert Fulton, MS, Gregory A. Abel, MDMPH, Tareq Al Baghdadi, MD, H. Joachim Deeg, MD, Amy E. DeZern, MD, Benjamin Ebert, MD, Pearlie Epling-Burnette, PhD PharmD, James M. Foran, MD, Edward J. Gorak, DO,MBA,MS, Steven D. Gore, MD, Rami S. Komrokji, MD, Jane Jijun Liu, MD, Jaroslaw P. Maciejewski, MD PhD, Eric Padron, MD, Wael Saber, MD MS, Daniel T. Starczynowski, PhD, Myron Waclawiw, PhD, Nancy DiFronzo, PhD, Mikkael A. Sekeres, MD MS, Ling Zhang, MD, Matthew J. Walter, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4271.
https://doi.org/10.1182/blood-2019-126978
Published: 2019
Journal Articles

Chromosome Banding Analysis Versus Genomic Microarrays: A Comparison of Methods for Genomic Complexity Risk Stratification in Chronic Lymphocytic Leukemia Patients with Complex Karyotype

Free
Silvia Ramos Campoy, Anna Puiggros, PhD, Silvia Bea, PhD, Sandrine Bougeon, Maria Jose Larrayoz, PhD, Guillem Clot, Dolors Costa, MD, Gian Matteo Rigolin, MD, Margarita Ortega, Laura Blanco, Rosa Collado, MD, Rocio N Salgado, PhD, María-Dolores García-Malo, MD, Andrea Campeny, Alberto Valiente, Ferran Nadeu, BSc, MSc, Julio Delgado, Tycho Baumann, Idoya Ancín, Marco Antonio Moro García, Eva Gimeno, MD PhD, Carol Moreno, MD PhD, Francesc Bosch, MD PhD, Ana Ferrer, MD PhD, Gonzalo Blanco, PhD, Maria Jose Calasanz, PhD BSc, Antonio Cuneo, MD, Claudia Haferlach, MD, Jacqueline Schoumans, PhD, Blanca Espinet, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4287.
https://doi.org/10.1182/blood-2019-126557
Published: 2019
Journal Articles

Inhibition of Acute Leukemia By a Small Molecule KYA1797K Which Destabilize RAS and β-Catenin

Free
Seungmin Hahn, MD, Mi Ra Lee, Jungwoo Han, MD PhD, Moon Kyu Kim, Seung-Hwan Oh, Chuhl Joo Lyu, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5758.
https://doi.org/10.1182/blood-2019-126374
Published: 2019
Journal Articles

Deregulated CXCR4-CXCL12 Signaling Impacts on the Pathogenesis of DLBCL

Free
Katrin Pansy, MSc, BSc, Julia Feichtinger, Barbara Ehall, Barbara Uhl, Hildegard T. Greinix, MD, Katharina Prochazka, MD, Christine Beham-Schmid, Peter Neumeister, MD, Tanja Wrodnigg, Karoline Fechter, Alexander Deutsch
Journal: Blood
Blood (2019) 134 (Supplement_1): 1519.
https://doi.org/10.1182/blood-2019-130029
Published: 2019
Journal Articles

Strategy for Identification of an Inherited Leukemia Predisposition in a 299 Patients Cohort with Tumor-Only Sequencing Data

Free
Almudena Aguilera Díaz, MSc, BS, Sara Palomino-Echeverria, MSc, BSc, Iria Vazquez, PhD BSc, Beñat Ariceta, BSc, Maria Jose Larrayoz, BSc, Amagoia Mañu, BSc, Zuriñe Blasco-Iturri, MSc, BSc, Matxalen Olivares Salaverri, MD, Maria Teresa Olave Rubio, MD, Teresa Bernal Del Castillo, MD PhD, Jose J. Rifon Roca, MD, Ana Alfonso Pierola, MD PhD, Felipe Prosper, MD PhD, Marta Fernández-Mercado, PhD MSc, BSc, Maria Jose Calasanz, PhD BSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 1415.
https://doi.org/10.1182/blood-2019-126634
Published: 2019
Journal Articles

High Interpatient Variability in Molecular MRD Response to Consolidation Chemotherapy in Acute Myeloid Leukemia

Free
Tracy Murphy, MDFRCP,FRCPath, Jinfeng Zou, PhD, Ting Ting Wang, Yangqiao Zheng, Zhen Zhao, Roman M Shapiro, MD, Vikas Gupta, MD FRCP, FRCPath, Dawn Maze, MDFRCPC,MSc, Caroline J McNamara, MBBS, Mark D. Minden, MD PhD, Aaron D Schimmer, MD PhD, Andre C. Schuh, MD, Hassan Sibai, MBBS, Karen W.L. Yee, MD, Tracy L. Stockley, PhD FCCMG, FACMG, Philip Zuzarte, PhD, Carolina Bocanegra, PhD, Lawrence Heisler, Paul Krzyzanowski, PhD, Trevor Pugh, Scott Bratman, MD PhD, Steven M Chan, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1424.
https://doi.org/10.1182/blood-2019-122890
Published: 2019
Journal Articles

The Molecular Basis of Long First Remissions in Normal Karyotype AML Patients

Free
Francesca Ferraro, MD PhD, Christopher A Miller, PhD, Amy Abdalla, Nichole Helton, Nathan Salomonis, PhD, Robert S Fulton, Catrina Fronick, BS, Sharon E Heath, Peter Westervelt, MD PhD, Timothy J Ley, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3827.
https://doi.org/10.1182/blood-2019-122967
Published: 2019
Journal Articles

Effect of Avelumab to Immune Response in AML: A Phase I Study of Avelumab in Combination with Decitabine As First Line Treatment of Unfit Patients

Free
Hong Zheng, MD PhD, Shin Mineishi, David F. Claxton, MD, Junjia Zhu, Chenchen Zhao, MD, Bei Jia, MD PhD, W. Christopher Ehmann, MD, Seema Naik, MD, Natthapol Songdej, Raymond J. Hohl
Journal: Blood
Blood (2019) 134 (Supplement_1): 3939.
https://doi.org/10.1182/blood-2019-125153
Published: 2019
Journal Articles

Interrogating the Spatial Architecture of Human Bone Marrow Via Imaging Mass Cytometry

Free
Karolyn A. Oetjen, MD, Diane E. Bender, PhD, Marianna B. Ruzinova, MD PhD, Stephen T. Oh, MD, Daniel C. Link, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3728.
https://doi.org/10.1182/blood-2019-127460
Published: 2019
Journal Articles

Inhibition of BMP-Smad Pathway Reduces Leukemic Stemness in Pediatric AML

Free
Xin Long, PhD, Chris Man, PhD, Padmini Narayanan, PhD, Elizabeth Seashore, MD, Michele Redell, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3731.
https://doi.org/10.1182/blood-2019-129074
Published: 2019
Journal Articles

Transcriptome Sequencing Demonstrates Unique Signature Associated with Durable Clinical Response to DC/AML Fusion Vaccine

Free
Jessica Liegel, MD, Manoj Bhasin, PhD, German A. Pihan, MD, Dina Stroopinsky, PhD, Beena Thomas, PhD, Shreya Sindhu, Haider Ghiasuddin, Emma Logan, Adam Morin, Marzia Capelletti, PhD MMSc, Shira Orr, PhD, Myrna Nahas, MD, Matthew Weinstock, MD, Maryam Rahimian, MD, Lina Bisharat, Shufen Meng, MD, Richard M. Stone, MD, Donald Kufe, MD, David E. Avigan, MD, Jacalyn Rosenblatt, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3832.
https://doi.org/10.1182/blood-2019-129451
Published: 2019
Journal Articles

PTPN11 Mutated Acute Myeloid Leukemia (AML) Features an Abundant Epichaperome Network and Is Sensitive to the Epichaperome Inhibitor PU-H71

Free
Justin D. Kaner, MD, Montreh Tavakkoli, MA,MD, Lisa Toudic, Brett M. Stevens, PhD, Craig T Jordan, PhD, Tony Taldone, PhD, Gabriela Chiosis, PhD, Ellen K. Ritchie, MD, Pinkal Desai, MDMPH, Michael B. Samuel, MD, Sangmin Lee, MD, Gail J. Roboz, MD, Monica L. Guzman, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3935.
https://doi.org/10.1182/blood-2019-128276
Published: 2019
Journal Articles

A Multisite Phase Ib Study of Pevonedistat, Azacitidine and Venetoclax (PAVE) for the Treatment of Subjects with Acute Myelogenous Leukemia (AML)

Free
Guru Subramanian Guru Guru Murthy, MBBS, Scott H. Kaufmann, MD PhD, Aniko Szabo, PhD, Arielle Baim, Ashish Anshu, Alexander Hinman, Laura C. Michaelis, MD, Sameem Abedin, MD, Karen-Sue B. Carlson, MD PhD, Lyndsey Runaas, MD, Ehab L. Atallah, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3837.
https://doi.org/10.1182/blood-2019-131728
Published: 2019
Journal Articles

The PRIME Trial: PARP Inhibition in IDH Mutant Effectiveness Trial. a Phase II Study of Olaparib in Isocitrate Dehydrogenase (IDH) Mutant Relapsed/Refractory Acute Myeloid Leukemia and Myelodysplastic Syndrome

Free
Namrata S Chandhok, MD, Wei Wei, MD PhD, Ranjit Bindra, MD PhD, Stephanie Halene, MD, Yu Shyr, Jing Li, PhD, Michael Berens, PhD, Chris Karlovich, PhD, S. Percy Ivy, MD, Thomas Prebet, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3909.
https://doi.org/10.1182/blood-2019-129168
Published: 2019