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Journal Articles

Acute Myeloid Leukemia Expands Osteoprogenitor Rich Niche in the Bone Marrow but Resorbs Mature Bone Causing Osteopenia/Osteoporosis in Animal Models

Bin Yuan, Stanley Ly, Khoa Nguyen, Vivien Tran, Kiersten Maldonado, Charles Kinglsey, Jared K Burks, PhD, Xin Zhou, PhD, Benoit deCrombrugghe, Michael Andreeff, MD PhD, Venkata Lokesh Battula, PhD

Blood (2018) 132 (Supplement 1): 86.

https://doi.org/10.1182/blood-2018-99-117258

Published: 2018

Journal Articles

Factor VIII Plays a Direct Role in Osteoblast Development

Emily Ann Larson, BS, Jason A Taylor, MD PhD

Blood (2017) 130 (Supplement 1): 3661.

https://doi.org/10.1182/blood.V130.Suppl_1.3661.3661

Published: 2017

Journal Articles

The Combination of Radium-223 Dichloride and Bortezomib Effectively Reduces Tumor Burden and Lesion Area in the Syngeneic, Systemic 5TGM1 Multiple Myeloma Mouse Model

Mari Suominen, Tiina Kähkönen, Jenni Mäki-Jouppila, Jukka P Rissanen, Anniina Luostarinen, Katja M Fagerlund, Birgitta Sjöholm, Esa Alhoniemi, Sanna Kakonen, PhD, Gerhard Siemeister, Dominik Mumberg, Jussi M Halleen, Karl Ziegelbauer, Arne Scholz

Blood (2017) 130 (Supplement 1): 1802.

https://doi.org/10.1182/blood.V130.Suppl_1.1802.1802

Published: 2017

Journal Articles

Mesenchymal Stem Cells (MSC) from Patients with Multiple Myeloma Promote Myeloid Cells to Become Granulocytic-Myeloid-Derived Suppressor Cells (G-MDSC) with Immunosuppressive, Bone Resorption and Pro-Angiogenic Activity

Cesarina Giallongo, Daniele Tibullo, PhD, Nunziatina Laura Parrinello, Piera La Cava, Giuseppina Camiolo, Nunzia Caporarello, Carmelina Daniela Anfuso, Fabrizio Puglisi, Concetta Conticello, MD, Maria Violetta Brundo, Alessandra Romano, MD PhD, Francesco Di Raimondo, MD

Blood (2016) 128 (22): 4458.

https://doi.org/10.1182/blood.V128.22.4458.4458

Published: 2016

Journal Articles

Contribution of High-Density Neutrophils to Multiple Myeloma Microenvironment Dysregulation

Alessandra Romano, MD PhD, Cesarina Giallongo, Nunziatina L Parrinello, Daniele Tibullo, PhD, Fabrizio Puglisi, Giusy Camiolo, Piera La Cava, Marina Parisi, maria Letizia Consoli, Concetta Conticello, MD, Francesco Di Raimondo, MD, Vanella Luca

Blood (2016) 128 (22): 5643.

https://doi.org/10.1182/blood.V128.22.5643.5643

Published: 2016

Journal Articles

Decreased In Vitro Osteoblast Mineralization in Primary Bone Marrow Stromal Cells (MSCs) Derived from FVIII-Deficient Mice

Emily A Larson, Jason A Taylor, MD PhD

Blood (2016) 128 (22): 560.

https://doi.org/10.1182/blood.V128.22.560.560

Published: 2016

Journal Articles

Netrin-1 Promotes Osteoclast Activity in Multiple Myeloma Under Hypoxic Conditions: Modulation By a RANKL Inhibitor

Narayanan Bhagavathi, PhD, Blau Talia, BA, Nicole Adell Doudican, PhD, Narayanan Narayanan, PhD, Amitabha Mazumder, MD

Blood (2015) 126 (23): 1781.

https://doi.org/10.1182/blood.V126.23.1781.1781

Published: 2015

Journal Articles

Direct Cell-To-Cell Interactions Between Osteocytes and Multiple Myeloma (MM) Cells Upregulate Sost and Downregulate OPG Expression In Osteocytes: Evidence For Osteocytic Contributions To MM-Induced Bone Disease

Jesus Delgado Calle, PhD, Teresita Bellido, PhD, G. David David Roodman, MD, PhD

Blood (2013) 122 (21): 3140.

https://doi.org/10.1182/blood.V122.21.3140.3140

Published: 2013

Journal Articles

Mouse Versus Human Extrinsic Cues Dictate Transformation Potential In BCR-ABL/BMI1-Induced Leukemia In Humanized Xenograft Models

Pallavi Sontakke, Richard W.J. Groen, PhD, Jennifer Jaques, Huipin Yuan, PhD, Anton Martens, PhD, Edo Vellenga, MD, PhD, Jan Jacob Schuringa, PhD

Blood (2013) 122 (21): 515.

https://doi.org/10.1182/blood.V122.21.515.515

Published: 2013

Journal Articles

Skeletal-Targeted, Osteolytic-Responsive Drug Delivery System Improves Anti-Tumor Efficacy in Multiple Myeloma.

Xuli Wang, PhD, Ye Yang, PhD, Scott Miller, PhD, Fenghuang Zhan, MD, PhD

Blood (2012) 120 (21): 3155.

https://doi.org/10.1182/blood.V120.21.3155.3155

Published: 2012

Journal Articles

Combination Effects of Nilotinib and Zoledronic Acid On Chronic Myeloid Leukemia Are Canceled in the Co-Culture System Which Mimic the Bone Marrow Microenvironment.

Masako Yokoo, MD, Yasushi Kubota, MD, PhD, Tatsuo Ichinohe, MD, PhD, Shinya Kimura, MD, PhD

Blood (2012) 120 (21): 2459.

https://doi.org/10.1182/blood.V120.21.2459.2459

Published: 2012

Journal Articles

Osteocytes Embedded Inside Bone Are Essential for G-CSF-Induced Hematopoietic Stem/Progenitor Mobilization

Noboru Asada, MD, Yoshio Katayama, MD, PhD, Mari Sato, DDS, PhD, Kentaro Minagawa, MD, PhD, Kanako Wakahashi, MD, Hiroki Kawano, MD, Yuko Kawano, MD, Akiko Sada, MD, PhD, Kyoji Ikeda, MD, Toshimitsu Matsui, MD, PhD, Mitsune Tanimoto

Blood (2011) 118 (21): 721.

https://doi.org/10.1182/blood.V118.21.721.721

Published: 2011

Journal Articles

Osteocytes Support Hematopoiesis by Altering the Bone Marrow Microenvironment Through Gsα Signaling

Daniela S. Krause, MD, PhD, Keertik Fulzele, PhD, Kevin Barry, Sutada Lotinun, Roland Baron, Lynda Bonewald, Jian Q Feng, Min Chen, Lee S Weinstein, Mary Bouxsein, David T. Scadden, MD, Paola Divieti-Pajevic, MD PhD

Blood (2011) 118 (21): 219.

https://doi.org/10.1182/blood.V118.21.219.219

Published: 2011

Journal Articles

Platelet-Derived Factors Allow Human Mesenchymal Stem Cells to Spontaneously Undergo Endochondral Bone Differentiation and Provide Bone Marrow Support in a Xenogenic In Vivo Model

Nathalie Etchart, PhD, Andreas Reinisch, MD, PhD, Anna Ortner, Margareta Frühwirth, Rokhsareh Rohban, Claudia Url, Katharina Schallmoser, MD, Christine Beham-Schmid, MD, Dirk Strunk, MD

Blood (2011) 118 (21): 1322.

https://doi.org/10.1182/blood.V118.21.1322.1322

Published: 2011

Journal Articles

Transplantation of human fetal blood stem cells in the osteogenesis imperfecta mouse leads to improvement in multiscale tissue properties

Maximilien Vanleene, Zahraa Saldanha, Kristy L. Cloyd, Gavin Jell, George Bou-Gharios, J. H. Duncan Bassett, Graham R. Williams, Nicholas M. Fisk, Michelle L. Oyen, Molly M. Stevens, Pascale V. Guillot, Sandra J. Shefelbine

Blood (2011) 117 (3): 1053–1060.

https://doi.org/10.1182/blood-2010-05-287565

Published: 2011

Includes: Supplemental data

Journal Articles

Osteoclasts Are Involved in the Maintenance of Dormant Leukemic Cells.

Asumi Yokota, MMSc, Shinya Kimura, MD, PhD, Ruriko Tanaka, MMSc, Miki Takeuchi, MD, Hisayuki Yao, MD, Kazuki Sakai, MD, Rina Nagao, Eishi Ashihara, MD, PhD, Taira Maekawa, MD, PhD

Blood (2009) 114 (22): 4245.

https://doi.org/10.1182/blood.V114.22.4245.4245

Published: 2009

Journal Articles

Clinical and Genetic Factors Underlying Acute Bone Mineral Density Loss by 100 Days after Blood and Marrow Transplantation: A Potential Early Regimen-Related Complication

Theresa Hahn, PhD, Song Yao, Shannon Smiley, Kathleen West, Minoo Battiwalla, Dominick Lamonica, Philip L McCarthy, Jr

Blood (2008) 112 (11): 52.

https://doi.org/10.1182/blood.V112.11.52.52

Published: 2008

Journal Articles

Roles of Osteoclasts in Leukemic Cells

Asumi Yokota, MMSc, Shinya Kimura, MD, PhD, Ruriko Tanaka, MMSc, Rina Nagao, Kazuki Sakai, MD, Hisayuki Yao, MD, Miki Takeuchi, MD, Makoto Kawatani, PhD, Hiroyuki Osada, PhD, Eishi Ashihara, MD, PhD, Taira Maekawa, MD, PhD

Blood (2008) 112 (11): 3184.

https://doi.org/10.1182/blood.V112.11.3184.3184

Published: 2008

Journal Articles

Multiple Myeloma Cell-Osteoblast Interaction Results in Impaired Bone Formation.

Sonia Vallet, MD, Teru Hideshima, MD, Samantha Pozzi, MD, Nileshwari Vaghela, Gaurav Gharti-Chhetri, Siddhartha Mukherjee, MD, Iris Breitkreutz, MD, Tanyel Kiziltepe, PhD, Yutaka Okawa, MD, Hiroshi Ikeda, MD, Loredana Santo, MD, Diana Cirstea, MD, Mario Boccadoro, MD, Kenneth C. Anderson, MD, Noopur Raje, MD

Blood (2007) 110 (11): 4764.

https://doi.org/10.1182/blood.V110.11.4764.4764

Published: 2007

Journal Articles

Bortezomib Transiently Inhibits Osteoclast Resorptive Activity in Cell Culture Conditions Mimicking In Vivo Intermittent Treatment.

Patrice Boissy, PhD, Thomas Lund, MD, Thomas L. Andersen, MSc, Torben Plesner, MD, Jean-Marie Delaisse, PhD

Blood (2006) 108 (11): 3508.

https://doi.org/10.1182/blood.V108.11.3508.3508

Published: 2006

NARROW

Acute Myeloid Leukemia Expands Osteoprogenitor Rich Niche in the Bone Marrow but Resorbs Mature Bone Causing Osteopenia/Osteoporosis in Animal Models

Factor VIII Plays a Direct Role in Osteoblast Development

The Combination of Radium-223 Dichloride and Bortezomib Effectively Reduces Tumor Burden and Lesion Area in the Syngeneic, Systemic 5TGM1 Multiple Myeloma Mouse Model

Mesenchymal Stem Cells (MSC) from Patients with Multiple Myeloma Promote Myeloid Cells to Become Granulocytic-Myeloid-Derived Suppressor Cells (G-MDSC) with Immunosuppressive, Bone Resorption and Pro-Angiogenic Activity

Contribution of High-Density Neutrophils to Multiple Myeloma Microenvironment Dysregulation

Decreased In Vitro Osteoblast Mineralization in Primary Bone Marrow Stromal Cells (MSCs) Derived from FVIII-Deficient Mice

Netrin-1 Promotes Osteoclast Activity in Multiple Myeloma Under Hypoxic Conditions: Modulation By a RANKL Inhibitor

Direct Cell-To-Cell Interactions Between Osteocytes and Multiple Myeloma (MM) Cells Upregulate Sost and Downregulate OPG Expression In Osteocytes: Evidence For Osteocytic Contributions To MM-Induced Bone Disease

Mouse Versus Human Extrinsic Cues Dictate Transformation Potential In BCR-ABL/BMI1-Induced Leukemia In Humanized Xenograft Models

Skeletal-Targeted, Osteolytic-Responsive Drug Delivery System Improves Anti-Tumor Efficacy in Multiple Myeloma.

Combination Effects of Nilotinib and Zoledronic Acid On Chronic Myeloid Leukemia Are Canceled in the Co-Culture System Which Mimic the Bone Marrow Microenvironment.

Osteocytes Embedded Inside Bone Are Essential for G-CSF-Induced Hematopoietic Stem/Progenitor Mobilization

Osteocytes Support Hematopoiesis by Altering the Bone Marrow Microenvironment Through Gsα Signaling

Platelet-Derived Factors Allow Human Mesenchymal Stem Cells to Spontaneously Undergo Endochondral Bone Differentiation and Provide Bone Marrow Support in a Xenogenic In Vivo Model

Transplantation of human fetal blood stem cells in the osteogenesis imperfecta mouse leads to improvement in multiscale tissue properties

Osteoclasts Are Involved in the Maintenance of Dormant Leukemic Cells.

Clinical and Genetic Factors Underlying Acute Bone Mineral Density Loss by 100 Days after Blood and Marrow Transplantation: A Potential Early Regimen-Related Complication

Roles of Osteoclasts in Leukemic Cells

Multiple Myeloma Cell-Osteoblast Interaction Results in Impaired Bone Formation.

Bortezomib Transiently Inhibits Osteoclast Resorptive Activity in Cell Culture Conditions Mimicking In Vivo Intermittent Treatment.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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