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Journal Articles

Safety and Efficacy of a Novel Mammalian-Derived Asparaginase without Glutaminase Activity in Combination with Venetoclax for Acute Myeloid Leukemia

Dhabya Majid, Zhe WANG, Bin Yuan, Mhd Yousuf Yassouf, Amanda Schalk, Basant T. Gamal, Qi Zhang Tatarata, Jessica Lynn Root, Araceli Isabella Garza, Annie Hoai Nguyen, Sammy Ferri-Borgogno, Patrick K. Reville, Arnon Lavie, Hussein A. Abbas
Journal: Blood
Blood (2024) 144 (Supplement 1): 2777.
https://doi.org/10.1182/blood-2024-203584
Published: 2024
Journal Articles

Blood-Based Proteomic Profiling Identifies Osmr As a Novel Biomarker

Hussein A. Abbas, Bofei Wang, Jennifer Marvin-Peek, Bin Yuan, Araceli Isabella Garza, Jessica Lynn Root, Andrea Arruda, Yiwei Liu, Courtney D. DiNardo, Tapan M. Kadia, Naval Daver, Philip L Lorenzi, Koji Sasaki, Steven M. Kornblau, Mark D. Minden, Farhad Ravandi, Hagop M. Kantarjian, Patrick K. Reville
Journal: Blood
Blood (2024) 144 (Supplement 1): 2912.
https://doi.org/10.1182/blood-2024-201725
Published: 2024
Journal Articles

Activin-like Kinase 2 (ALK2/ACVR1) Is a Resistance Factor and Therapeutic Vulnerability to FLT3 Inhibition in Acute Myeloid Leukemia

Anudishi Tyagi, Stanley Ly, Bin Yuan, Fouad El-Dana, Vivek Anand, Appalaraju Jaggupilli, Gautam Borthakur, Jason M Foulks, Steven L. Warner, Venkata Lokesh Battula
Journal: Blood
Blood (2022) 140 (Supplement 1): 3052–3053.
https://doi.org/10.1182/blood-2022-167580
Published: 2022
Journal Articles

Evidence supporting a role for the immune checkpoint protein B7-H3 in NK cell-mediated cytotoxicity against AML

Anudishi Tyagi, Stanley Ly, Fouad El-Dana, Bin Yuan, Appalaraju Jaggupilli, Sabrina Grimm, Marina Konopleva, Hans-Jörg Bühring, V. Lokesh Battula
Journal: Blood
Blood (2022) 139 (18): 2782–2796.
https://doi.org/10.1182/blood.2021014671
Published: 2022
Includes: Supplemental data
Journal Articles

Anti-B7-H3 Antibody (T-1A5) Blocks Immunomodulatory Function of B7-H3 and Enhances NK Cell-Mediated Cytotoxicity Against Acute Myeloid Leukemia Cells

Anudishi Tyagi, Stanley Ly, Fouad El-Dana, Bin Yuan, Sabrina Grimm, Hans-Jörg Bühring, Venkata Lokesh Battula
Journal: Blood
Blood (2021) 138 (Supplement 1): 3336.
https://doi.org/10.1182/blood-2021-151535
Published: 2021
Journal Articles

TP-0184, a Novel FLT3-ALK2 Dual Inhibitor, Targets Amino Acid Transport and Biosynthesis in AML Cells and Sensitizes AML Cells to Chemotherapy and BCL2 Inhibition

Anudishi Tyagi, Stanley Ly, Bin Yuan, Fouad El-Dana, Appalaraju Jaggupilli, Jason M Foulks, Steven L. Warner, Venkata Lokesh Battula
Journal: Blood
Blood (2021) 138 (Supplement 1): 376.
https://doi.org/10.1182/blood-2021-151251
Published: 2021
Journal Articles

AML Cells Alter Bone Homeostasis By Promoting the Formation of Immature Bone and Resorption of Mature Bone That Supports Leukemia Progression

Anudishi Tyagi, PhD, Bin Yuan, Stanley Ly, Fouad El-Dana, MD, Vinitha Mary Kuruvilla, MSc, Qi Zhang, PhD, Christine B Peterson, Xin Zhou, PhD, Benoit deCrombrugghe, Michael Andreeff, MD PhD, Marina Konopleva, MD PhD, Behrang Amini, MD PhD, Venkata Lokesh Battula, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 27.
https://doi.org/10.1182/blood-2020-142777
Published: 2020
Journal Articles

Concomitant Targeting of FLT3 and BTK with CG'806 Overcomes FLT3-Inhibitor Resistance through Inhibition of Autophagy

Weiguo Zhang, MD PhD, Guopan Yu, MD, PhD, Hongying Zhang, MD, PhD, Charlie Ly, BS, Bin Yuan, Vivian Ruvolo, MS, Sujan Piya, PhD, Seemana Bhattacharya, PhD, Qi Zhang, PhD, Gautam Borthakur, MD, Venkata Lokesh Battula, PhD, Marina Y. Konopleva, MD PhD, William G Rice, PhD, Michael Andreeff, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2635.
https://doi.org/10.1182/blood-2018-99-116643
Published: 2018
Journal Articles

Acute Myeloid Leukemia Expands Osteoprogenitor Rich Niche in the Bone Marrow but Resorbs Mature Bone Causing Osteopenia/Osteoporosis in Animal Models

Bin Yuan, Stanley Ly, Khoa Nguyen, Vivien Tran, Kiersten Maldonado, Charles Kinglsey, Jared K Burks, PhD, Xin Zhou, PhD, Benoit deCrombrugghe, Michael Andreeff, MD PhD, Venkata Lokesh Battula, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 86.
https://doi.org/10.1182/blood-2018-99-117258
Published: 2018
Journal Articles

Bone Marrow Stromal Cells Induce ALDH+ Stem Cell Phenotype and Chemotherapy Resistance in AML Cells through TGF-β1 Mediated Signaling: Reversal By TGFβ Inhibitor Galunisertib

Ximin Zhou, Bin Yuan, Yuanqing Yan, Khoa Nguyen, Vivian Ruvolo, PhD, Hong Mu, MD PhD, Teresa McQueen, MS, Elizabeth J Shpall, MD, Kim-Ann Do, Marina Konopleva, MD PhD, Michael Andreeff, MD PhD, Venkata Lokesh Battula, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1163.
https://doi.org/10.1182/blood.V130.Suppl_1.1163.1163
Published: 2017