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Journal Articles

Canonical Signaling By TGF Family Members in Mesenchymal Stromal Cells Is Dispensable for Hematopoietic Niche Maintenance Under Basal and Stress Conditions

Joseph R. Krambs, BS, Grazia Abou Ezzi, PhD, Juo-Chin Yao, Justin T. Li, Daniel C. Link, MD

Blood (2019) 134 (Supplement_1): 1209.

https://doi.org/10.1182/blood-2019-128693

Published: 2019

Journal Articles

Inhibition of BMP-Smad Pathway Reduces Leukemic Stemness in Pediatric AML

Xin Long, PhD, Chris Man, PhD, Padmini Narayanan, PhD, Elizabeth Seashore, MD, Michele Redell, MD PhD

Blood (2019) 134 (Supplement_1): 3731.

https://doi.org/10.1182/blood-2019-129074

Published: 2019

Journal Articles

The Role of the BMP Pathway in Sustaining CML Stem Cells in the Bone Marrow Niche

Caroline Busch, BSc, MSc, Chloe Gulliver, BSc, MSc, Theresa Mulholland, BSc, Michele Zagnoni, BSc, MSc, PhD, Catherine C. Berry, BSc,PhD, Helen Wheadon, BSc, PhD

Blood (2019) 134 (Supplement_1): 3732.

https://doi.org/10.1182/blood-2019-123967

Published: 2019

Journal Articles

Paracrine Bone Morphogenetic Protein Signaling in Iron Homeostasis

Jodie L. Babitt, MD

Blood (2019) 134 (Supplement_1): SCI-26.

https://doi.org/10.1182/blood-2019-121069

Published: 2019

Journal Articles

Hepatocyte Iron Content Controls BMP6-Dependent Hepcidin Regulation

Sandro Altamura, PhD, Silvia Colucci, MSc, Julia Schmidt, Katja Muedder, Joana Neves, Matthias Hentze, Prof., Martina U. Muckenthaler, PhD

Blood (2018) 132 (Supplement 1): 3626.

https://doi.org/10.1182/blood-2018-99-116109

Published: 2018

Journal Articles

Transcriptomic Analysis Reveals Erythroferrone Modulates BMP6 Signaling Pathways Involved in Iron Homeostasis and Metabolism

Reema Jasuja, PhD, Anagha Sawant, Debra D Pittman, MS, Jie Quan

Blood (2018) 132 (Supplement 1): 1049.

https://doi.org/10.1182/blood-2018-99-118724

Published: 2018

Journal Articles

BMP4 Gene Therapy Inhibits Myeloma Tumor Growth, but Has a Negative Impact on Bone

Toril Holien, PhD, Marita Westhrin, PhD, Siv Helen Moen, PhD, Muhammad Zahoor, PhD, Glenn Buene, Berit Størdal, Hanne Hella, Huipin Yuan, Joost D de Bruijn, PhD, Anton Martens, PhD, Richard WJ Groen, PhD, Fatima Bosch, PhD, Ulf Smith, MD PhD, Anders Sundan, PhD, Therese Standal, PhD

Blood (2018) 132 (Supplement 1): 1928.

https://doi.org/10.1182/blood-2018-99-112429

Published: 2018

Journal Articles

Deletion of BMP6 Worsens the Phenotype of Hemojuvelin-Deficient Mice and Attenuates Hepcidin Levels Reached after LPS Stimulation

Chloé Latour, Céline Besson-Fournier, Ophélie Gourbeyre, Delphine Meynard, PhD, Aguilar-Martinez Patricia, MD PhD, Marie-Paule Roth, MD, Helene Coppin, PhD

Blood (2017) 130 (Supplement 1): 226.

https://doi.org/10.1182/blood.V130.Suppl_1.226.226

Published: 2017

Journal Articles

Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice

Susanna Canali, Kimberly B. Zumbrennen-Bullough, Amanda B. Core, Chia-Yu Wang, Manfred Nairz, Richard Bouley, Filip K. Swirski, Jodie L. Babitt

Blood (2017) 129 (4): 405–414.

https://doi.org/10.1182/blood-2016-06-721571

Published: 2017

Includes: Supplemental data

Journal Articles

The Bone Marrow Niche Distinguishes Young and Old Leukemia

Shahzya S Chaudhury, MBBChir, MA (cantab), Helen Wheadon, PhD, Brenda Gibson, MD PhD, Karen Keeshan, PhD

Blood (2016) 128 (22): 1548.

https://doi.org/10.1182/blood.V128.22.1548.1548

Published: 2016

Journal Articles

MASL1 Is a Critical Modifier of Hepcidin Expression Via Smad1/5/8 Phosphorylation in the Bone Morphogenetic Protein (BMP) Signaling Pathway

Chutima Kumkhaek, PhD, Christian LaChance, Wulin Aerbajinai, MD PhD, Jianqiong Zhu, Griffin P. Rodgers, MD

Blood (2016) 128 (22): 1275.

https://doi.org/10.1182/blood.V128.22.1275.1275

Published: 2016

Journal Articles

The ALK-2 Inhibitor, TP-0184, Demonstrates High Distribution to the Liver Contributing to Significant Preclinical Efficacy in Mouse Models of Anemia of Chronic Disease

Peter Peterson, PhD, Wontak Kim, Hillary Haws, Clifford J. Whatcott, PhD, Adam Siddiqui-Jain, PhD, David J. Bearss, PhD, Steven L. Warner, PhD

Blood (2016) 128 (22): 263.

https://doi.org/10.1182/blood.V128.22.263.263

Published: 2016

Journal Articles

Pomalidomide and Dexamethasone Regulate Human Erythroid Progenitor Signaling through Two Distinct Pathways

Brian M. Dulmovits, MS, Nan Wang, PhD, Corinne LaVasseur, BA, Julien Papoin, MS, Hongxia Yan, MS, Xiuli An, MD PhD, Jeffrey M Lipton, MD PhD, Narla Mohandas, Anupama Narla, MD, Lionel Blanc, PhD

Blood (2016) 128 (22): 2423.

https://doi.org/10.1182/blood.V128.22.2423.2423

Published: 2016

Journal Articles

Identification of New BMP6 Pro-Peptide Mutations in Patients with Unexplained Iron-Overload

Chiara Piubelli, PhD, Annalisa Castagna, PhD, Giacomo Marchi, MD, Monica Rizzi, MD, Fabiana Busti, MD, Monia Marchetti, MD PhD, Marco De Gobbi, MD PhD, Antonella Roetto, PhD BSc, Luciano Xumerle, Alejandro Giorgetti, PhD, Massimo Delledonne, PhD, Oliviero Olivieri, MD, Domenico Girelli, MD PhD

Blood (2016) 128 (22): 264.

https://doi.org/10.1182/blood.V128.22.264.264

Published: 2016

Journal Articles

Preclinical Modeling of ACVR1-Dependent Hepcidin Production and Anemia By Momelotinib

Matthew Warr, Malte Asshoff, Jim Zheng, Shringi Sharma, Pat Maciejewski, Guenter Weiss, Igor Theurl, J. Andrew Whitney

Blood (2016) 128 (22): 1967.

https://doi.org/10.1182/blood.V128.22.1967.1967

Published: 2016

Journal Articles

Identification of Two Distinct Poor Prognostic Subgroups Related to High Expression of BMP2 or PRDM16 in Pediatric AML

Yusuke Hara, MD, Norio Shiba, MD PhD, Genki Yamato, MD, Jun Okubo, MD PhD, Kentaro Ohki, MD PhD, Myoung-Ja Park, MD PhD, Manabu Sotomatsu, MD, Daisuke Tomizawa, MD, PhD, Tomohiko Taki, MD PhD, Akitoshi Kinoshita, MD PhD, Nobutaka Kiyokawa, MD PhD, Takashi Taga, MD PhD, Hirokazu Arakawa, MD PhD, Akio Tawa, MD PhD, Keizo Horibe, MD PhD, Souichi Adachi, MD, PhD, Yasuhide Hayashi, MD PhD

Blood (2016) 128 (22): 2854.

https://doi.org/10.1182/blood.V128.22.2854.2854

Published: 2016

Journal Articles

Thrombopoietin (TPO) Induces Hematopoietic Differentiation of Mouse ES Cells Via HIF-1 Alpha-Dependent Activation of a BMP4 Autoregulatory Loop

Azadeh Zahabi, Tatsuya Morishima, MD PhD, Andri Pramono, Dan Lan, Lothar Kanz, MD, Karl Welte, MD, Julia Skokowa, Prof. Dr.

Blood (2015) 126 (23): 1186.

https://doi.org/10.1182/blood.V126.23.1186.1186

Published: 2015

Journal Articles

Acute Myeloid Leukemia (AML) Cells Alter the Bone Marrow Microenvironment By Inducing Osteogenic and Suppressing Adipogenic Differentiation of MSCs through BMP-RUNX2-CTGF Mediated Mechanisms

Venkata Lokesh Battula, PhD, Phuong M Le, Jeffrey Sun, B.S., Hong Mu, MD PhD, Teresa Mc.Queen, M.S., Elizabeth J Shpall, MD, Marina Konopleva, MD PhD, Carlos E. Bueso-Ramos, MD, Melvyn Harrington, MD, Catherine W Palisch, MD, Michael Andreeff, MD PhD

Blood (2015) 126 (23): 2403.

https://doi.org/10.1182/blood.V126.23.2403.2403

Published: 2015

Journal Articles

Establishment of a Mouse Model of Aplastic Anemia Complicated By Iron Overload

Dijiong Wu, M.M., Xiaowen Wen, M.M., Baodong Ye, MD PhD, Wenbin Liu, M.M., Yanting Gao, M.M., Yiping Shen, BA, Yuhong Zhou, M.M., Jie Jin, MD PhD

Blood (2015) 126 (23): 4555.

https://doi.org/10.1182/blood.V126.23.4555.4555

Published: 2015

Journal Articles

Innovative Oral Iron Supplement (Sucrosomial Iron ® ) Is Able to Downregulate Hepcidin Release during Inflammation: In Vitro Study

Germano Tarantino, MD, Elisa Brilli, PhD, Giulio Giordano, MD, Alessandro Torelli, Francesco Equitani, MD

Blood (2015) 126 (23): 4563.

https://doi.org/10.1182/blood.V126.23.4563.4563

Published: 2015

NARROW

Canonical Signaling By TGF Family Members in Mesenchymal Stromal Cells Is Dispensable for Hematopoietic Niche Maintenance Under Basal and Stress Conditions

Inhibition of BMP-Smad Pathway Reduces Leukemic Stemness in Pediatric AML

The Role of the BMP Pathway in Sustaining CML Stem Cells in the Bone Marrow Niche

Paracrine Bone Morphogenetic Protein Signaling in Iron Homeostasis

Hepatocyte Iron Content Controls BMP6-Dependent Hepcidin Regulation

Transcriptomic Analysis Reveals Erythroferrone Modulates BMP6 Signaling Pathways Involved in Iron Homeostasis and Metabolism

BMP4 Gene Therapy Inhibits Myeloma Tumor Growth, but Has a Negative Impact on Bone

Deletion of BMP6 Worsens the Phenotype of Hemojuvelin-Deficient Mice and Attenuates Hepcidin Levels Reached after LPS Stimulation

Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice

The Bone Marrow Niche Distinguishes Young and Old Leukemia

MASL1 Is a Critical Modifier of Hepcidin Expression Via Smad1/5/8 Phosphorylation in the Bone Morphogenetic Protein (BMP) Signaling Pathway

The ALK-2 Inhibitor, TP-0184, Demonstrates High Distribution to the Liver Contributing to Significant Preclinical Efficacy in Mouse Models of Anemia of Chronic Disease

Pomalidomide and Dexamethasone Regulate Human Erythroid Progenitor Signaling through Two Distinct Pathways

Identification of New BMP6 Pro-Peptide Mutations in Patients with Unexplained Iron-Overload

Preclinical Modeling of ACVR1-Dependent Hepcidin Production and Anemia By Momelotinib

Identification of Two Distinct Poor Prognostic Subgroups Related to High Expression of BMP2 or PRDM16 in Pediatric AML

Thrombopoietin (TPO) Induces Hematopoietic Differentiation of Mouse ES Cells Via HIF-1 Alpha-Dependent Activation of a BMP4 Autoregulatory Loop

Acute Myeloid Leukemia (AML) Cells Alter the Bone Marrow Microenvironment By Inducing Osteogenic and Suppressing Adipogenic Differentiation of MSCs through BMP-RUNX2-CTGF Mediated Mechanisms

Establishment of a Mouse Model of Aplastic Anemia Complicated By Iron Overload

Innovative Oral Iron Supplement (Sucrosomial Iron ® ) Is Able to Downregulate Hepcidin Release during Inflammation: In Vitro Study

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American Society of Hematology

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American Society of Hematology

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