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Journal Articles

BMP4 Gene Therapy Inhibits Myeloma Tumor Growth, but Has a Negative Impact on Bone

Toril Holien, PhD, Marita Westhrin, PhD, Siv Helen Moen, PhD, Muhammad Zahoor, PhD, Glenn Buene, Berit Størdal, Hanne Hella, Huipin Yuan, Joost D de Bruijn, PhD, Anton Martens, PhD, Richard WJ Groen, PhD, Fatima Bosch, PhD, Ulf Smith, MD PhD, Anders Sundan, PhD, Therese Standal, PhD

Blood (2018) 132 (Supplement 1): 1928.

https://doi.org/10.1182/blood-2018-99-112429

Published: 2018

Journal Articles

Establishing human leukemia xenograft mouse models by implanting human bone marrow–like scaffold-based niches

Antonella Antonelli, Willy A. Noort, Jenny Jaques, Bauke de Boer, Regina de Jong-Korlaar, Annet Z. Brouwers-Vos, Linda Lubbers-Aalders, Jeroen F. van Velzen, Andries C. Bloem, Huipin Yuan, Joost D. de Bruijn, Gert J. Ossenkoppele, Anton C. M. Martens, Edo Vellenga, Richard W. J. Groen, Jan Jacob Schuringa

Blood (2016) 128 (25): 2949–2959.

https://doi.org/10.1182/blood-2016-05-719021

Published: 2016

Includes: Supplemental data

Journal Articles

Addition of the Vascular Niche Component to the Human Bone Marrow-like Scaffold Model

Willy A Noort, PhD, Regina de Jong-Korlaar, Linda Lubbers-Aalders, Huipin Yuan, PhD, Joost D de Bruijn, PhD, Constantine S Mitsiades, MD PhD, Anton CM Martens, PhD, Richard WJ Groen, PhD

Blood (2015) 126 (23): 2402.

https://doi.org/10.1182/blood.V126.23.2402.2402

Published: 2015

Journal Articles

Establishing Human Niche Xenograft Models for Myeloid and Lymphoid Leukemia Driven By MLL-AF9

Marco Carretta, MSc, Jennifer Jaques, Bauke de Boer, MSc, Huipin Yuan, PhD, Anton C. Martens, PhD, Edo Vellenga, MDPhD, Richard W.J. Groen, PhD, Jan Jacob Schuringa, PhD

Blood (2014) 124 (21): 4781.

https://doi.org/10.1182/blood.V124.21.4781.4781

Published: 2014

Journal Articles

Evaluation of Extrinsic and Intrinsic Cues Involved in BCR-ABL-Induced Leukemogenesis

Pallavi Suhas Sontakke, MSC, Richard W.J. Groen, PhD, Katarzyna Koczula, MSC, Jennifer Jaques, Huipin Yuan, PhD, Ulrich Günther, PhD, Anton C. Martens, PhD, Edo Vellenga, MD PhD, Jan J. Schuringa, PhD

Blood (2014) 124 (21): 515.

https://doi.org/10.1182/blood.V124.21.515.515

Published: 2014

Journal Articles

Disregulated Osteogenesis By Mesenchymal Stromal Cells (MSC) After In Vivo Exposure To Multiple Myeloma: Studies In a Novel Humanized Mouse Model For Bone Remodelling In Myeloma

Richard W.J. Groen, PhD, Willy A. Noort, PhD, Jessica Sigmans, Aniek van Stralen, Linda Aalders, Reinier Raymakers, MD, PhD, Huipin Yuan, PhD, Constantine S. Mitsiades, MD, PhD, Anton Martens, PhD

Blood (2013) 122 (21): 1906.

https://doi.org/10.1182/blood.V122.21.1906.1906

Published: 2013

Journal Articles

Mouse Versus Human Extrinsic Cues Dictate Transformation Potential In BCR-ABL/BMI1-Induced Leukemia In Humanized Xenograft Models

Pallavi Sontakke, Richard W.J. Groen, PhD, Jennifer Jaques, Huipin Yuan, PhD, Anton Martens, PhD, Edo Vellenga, MD, PhD, Jan Jacob Schuringa, PhD

Blood (2013) 122 (21): 515.

https://doi.org/10.1182/blood.V122.21.515.515

Published: 2013

Journal Articles

Daratumumab, a Novel Therapeutic Human CD38 Monoclonal Antibody, Induces Killing of Refractory Patient-Derived Multiple Myeloma Cells, Growing in a Novel Humanized Mouse MM Model

Willy A Noort, PhD, Richard W.J. Groen, PhD, Reinier Raymakers, MD, PhD, Linda Aalders, Frans M Hofhuis, Berris Van Kessel, Jeroen F Van Velzen, Joost de Bruijn, PhD, Huipin Yuan, PhD, Jeroen Lammerts van Bueren, PhD, Andries C Bloem, PhD, Paul W.H.I. Parren, PhD, Henk Lokhorst, MD, Tuna Mutis, MD PhD, Anton C.M. Martens, PhD

Blood (2012) 120 (21): 940.

https://doi.org/10.1182/blood.V120.21.940.940

Published: 2012

Journal Articles

Daratumumab, a Novel Human CD38 Monoclonal Antibody for Treatment of Multiple Myeloma, Prevents Intra-Medullary Spreading of Patient Derived Multiple Myeloma Cells Growing in a Humanized Mouse Model

Willy A Noort, PhD, Richard W.J. Groen, PhD, Reinier Raymakers, MD, PhD, Linda Aalders, Joost de Bruijn, PhD, Huipin Yuan, PhD, Jeroen Lammerts van Bueren, PhD, Paul W.H.I. Parren, PhD, Henk Lokhorst, MD, Tuna Mutis, MD PhD, Anton C.M. Martens, PhD

Blood (2012) 120 (21): 1834.

https://doi.org/10.1182/blood.V120.21.1834.1834

Published: 2012

Journal Articles

Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma

Blood (2012) 120 (3): e9–e16.

https://doi.org/10.1182/blood-2012-03-414920

Published: 2012

Includes: Supplemental data

NARROW

BMP4 Gene Therapy Inhibits Myeloma Tumor Growth, but Has a Negative Impact on Bone

Establishing human leukemia xenograft mouse models by implanting human bone marrow–like scaffold-based niches

Addition of the Vascular Niche Component to the Human Bone Marrow-like Scaffold Model

Establishing Human Niche Xenograft Models for Myeloid and Lymphoid Leukemia Driven By MLL-AF9

Evaluation of Extrinsic and Intrinsic Cues Involved in BCR-ABL-Induced Leukemogenesis

Disregulated Osteogenesis By Mesenchymal Stromal Cells (MSC) After In Vivo Exposure To Multiple Myeloma: Studies In a Novel Humanized Mouse Model For Bone Remodelling In Myeloma

Mouse Versus Human Extrinsic Cues Dictate Transformation Potential In BCR-ABL/BMI1-Induced Leukemia In Humanized Xenograft Models

Daratumumab, a Novel Therapeutic Human CD38 Monoclonal Antibody, Induces Killing of Refractory Patient-Derived Multiple Myeloma Cells, Growing in a Novel Humanized Mouse MM Model

Daratumumab, a Novel Human CD38 Monoclonal Antibody for Treatment of Multiple Myeloma, Prevents Intra-Medullary Spreading of Patient Derived Multiple Myeloma Cells Growing in a Humanized Mouse Model

Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma

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American Society of Hematology

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ASH Publications

American Society of Hematology

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