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Journal Articles

Establishing human leukemia xenograft mouse models by implanting human bone marrow–like scaffold-based niches

Antonella Antonelli, Willy A. Noort, Jenny Jaques, Bauke de Boer, Regina de Jong-Korlaar, Annet Z. Brouwers-Vos, Linda Lubbers-Aalders, Jeroen F. van Velzen, Andries C. Bloem, Huipin Yuan, Joost D. de Bruijn, Gert J. Ossenkoppele, Anton C. M. Martens, Edo Vellenga, Richard W. J. Groen, Jan Jacob Schuringa

Blood (2016) 128 (25): 2949–2959.

https://doi.org/10.1182/blood-2016-05-719021

Published: 2016

Includes: Supplemental data

Journal Articles

Addition of the Vascular Niche Component to the Human Bone Marrow-like Scaffold Model

Willy A Noort, PhD, Regina de Jong-Korlaar, Linda Lubbers-Aalders, Huipin Yuan, PhD, Joost D de Bruijn, PhD, Constantine S Mitsiades, MD PhD, Anton CM Martens, PhD, Richard WJ Groen, PhD

Blood (2015) 126 (23): 2402.

https://doi.org/10.1182/blood.V126.23.2402.2402

Published: 2015

Journal Articles

CD38 Chimeric Antigen Receptor Engineered T Cells As Therapeutic Tools for Multiple Myeloma

Esther Drent, Richard Groen, PhD, Willy A. Noort, PhD, Jeroen Lammerts van Bueren, PhD, Paul W.H.I. Parren, PhD, Jurgen H Kuball, MDPhD, Zsolt Sebestyen, PhD, Niels W.C.J. van de Donk, MDPhD, Anton C. Martens, PhD, Henk M. Lokhorst, MDPhD, Tuna Mutis, MDPhD

Blood (2014) 124 (21): 4759.

https://doi.org/10.1182/blood.V124.21.4759.4759

Published: 2014

Journal Articles

Disregulated Osteogenesis By Mesenchymal Stromal Cells (MSC) After In Vivo Exposure To Multiple Myeloma: Studies In a Novel Humanized Mouse Model For Bone Remodelling In Myeloma

Richard W.J. Groen, PhD, Willy A. Noort, PhD, Jessica Sigmans, Aniek van Stralen, Linda Aalders, Reinier Raymakers, MD, PhD, Huipin Yuan, PhD, Constantine S. Mitsiades, MD, PhD, Anton Martens, PhD

Blood (2013) 122 (21): 1906.

https://doi.org/10.1182/blood.V122.21.1906.1906

Published: 2013

Journal Articles

CD38-Targeted Immunochemotherapy Of Multiple Myeloma: Preclinical Evidence For Its Combinatorial Use In Lenalidomide and Bortezomib Refractory/Intolerant MM Patients

Inger S. Nijhof, MD, Willy A. Noort, PhD, Jeroen Lammerts van Bueren, PhD, Berris van Kessel, Joost M. Bakker, PhD, Paul W.H.I. Parren, PhD, Richard W.J. Groen, PhD, Niels W.C.J. van de Donk, MD, PhD, Henk Lokhorst, Tuna Mutis, MD, PhD, Anton Martens, PhD

Blood (2013) 122 (21): 277.

https://doi.org/10.1182/blood.V122.21.277.277

Published: 2013

Journal Articles

Daratumumab, a Novel Therapeutic Human CD38 Monoclonal Antibody, Induces Killing of Refractory Patient-Derived Multiple Myeloma Cells, Growing in a Novel Humanized Mouse MM Model

Willy A Noort, PhD, Richard W.J. Groen, PhD, Reinier Raymakers, MD, PhD, Linda Aalders, Frans M Hofhuis, Berris Van Kessel, Jeroen F Van Velzen, Joost de Bruijn, PhD, Huipin Yuan, PhD, Jeroen Lammerts van Bueren, PhD, Andries C Bloem, PhD, Paul W.H.I. Parren, PhD, Henk Lokhorst, MD, Tuna Mutis, MD PhD, Anton C.M. Martens, PhD

Blood (2012) 120 (21): 940.

https://doi.org/10.1182/blood.V120.21.940.940

Published: 2012

Journal Articles

Daratumumab, a Novel Human CD38 Monoclonal Antibody for Treatment of Multiple Myeloma, Prevents Intra-Medullary Spreading of Patient Derived Multiple Myeloma Cells Growing in a Humanized Mouse Model

Willy A Noort, PhD, Richard W.J. Groen, PhD, Reinier Raymakers, MD, PhD, Linda Aalders, Joost de Bruijn, PhD, Huipin Yuan, PhD, Jeroen Lammerts van Bueren, PhD, Paul W.H.I. Parren, PhD, Henk Lokhorst, MD, Tuna Mutis, MD PhD, Anton C.M. Martens, PhD

Blood (2012) 120 (21): 1834.

https://doi.org/10.1182/blood.V120.21.1834.1834

Published: 2012

Journal Articles

Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma

Blood (2012) 120 (3): e9–e16.

https://doi.org/10.1182/blood-2012-03-414920

Published: 2012

Includes: Supplemental data

Journal Articles

Reconstructing the Human Hematopoietic Niche: Opportunities for Studying Normal and Malignant Hematopoiesis,

Richard W Groen, PhD, Willy A Noort, PhD, Reinier Raymakers, MD, PhD, Henk-Jan Prins, Msc, Linda Aalders, Frans M Hofhuis, Berris van Kessel, Petra Moerer, Henk Rozemuller, PhD, Jan J. Schuringa, PhD, Joost de Bruijn, PhD, Michel de Weers, PhD, Paul W.H.I. Parren, PhD, Henk M. Lokhorst, MD, Tuna Mutis, MD PhD, Anton CM Martens, PhD

Blood (2011) 118 (21): 3412.

https://doi.org/10.1182/blood.V118.21.3412.3412

Published: 2011

Journal Articles

Migration Potential of Human Mesenchymal Stromal Cells Is Determined by Origin of Tissue Rather Than Their Developmental Stage

Marijke W. Maijenburg, Willy A. Noort, PhD, Marion Kleijer, Charlotte J.A. Kompier, Kees Weijer, PhD, Jaap D. van Buul, PhD, C. Ellen van der Schoot, MD, PhD, Carlijn Voermans, PhD

Blood (2008) 112 (11): 4743.

https://doi.org/10.1182/blood.V112.11.4743.4743

Published: 2008

Journal Articles

Colony Forming Unit-Endothelial Cells (CFU-EC) Are Derived from CD14 + Cells and Need Support by CD14 − Cells.

Rachel T. Van Beem, MSc, Willy A. Noort, PhD, Marion Kleijer, Jaap Jan Zwaginga, MD, PhD, C. Ellen Van Der Schoot, MD, PhD

Blood (2005) 106 (11): 3685.

https://doi.org/10.1182/blood.V106.11.3685.3685

Published: 2005

Journal Articles

Amniotic fluid as a novel source of mesenchymal stem cells for therapeutic transplantation

Pieternella S. in `t Anker, Sicco A. Scherjon, Carin Kleijburg-van der Keur, Willy A. Noort, Frans H. J. Claas, Roelof Willemze, Willem E. Fibbe, Humphrey H. H. Kanhai

Blood (2003) 102 (4): 1548–1549.

https://doi.org/10.1182/blood-2003-04-1291

Published: 2003

Journal Articles

Similar repopulating capacity of mitotically active and resting umbilical cord blood CD34 + cells in NOD/SCID mice

Jannine Wilpshaar, J. H. Frederik Falkenburg, Xia Tong, Willy A. Noort, Robert Breese, Doug Heilman, Humphrey Kanhai, Christie M. Orschell-Traycoff, Edward F. Srour

Blood (2000) 96 (6): 2100–2107.

https://doi.org/10.1182/blood.V96.6.2100

Published: 2000

NARROW

Establishing human leukemia xenograft mouse models by implanting human bone marrow–like scaffold-based niches

Addition of the Vascular Niche Component to the Human Bone Marrow-like Scaffold Model

CD38 Chimeric Antigen Receptor Engineered T Cells As Therapeutic Tools for Multiple Myeloma

Disregulated Osteogenesis By Mesenchymal Stromal Cells (MSC) After In Vivo Exposure To Multiple Myeloma: Studies In a Novel Humanized Mouse Model For Bone Remodelling In Myeloma

CD38-Targeted Immunochemotherapy Of Multiple Myeloma: Preclinical Evidence For Its Combinatorial Use In Lenalidomide and Bortezomib Refractory/Intolerant MM Patients

Daratumumab, a Novel Therapeutic Human CD38 Monoclonal Antibody, Induces Killing of Refractory Patient-Derived Multiple Myeloma Cells, Growing in a Novel Humanized Mouse MM Model

Daratumumab, a Novel Human CD38 Monoclonal Antibody for Treatment of Multiple Myeloma, Prevents Intra-Medullary Spreading of Patient Derived Multiple Myeloma Cells Growing in a Humanized Mouse Model

Reconstructing the human hematopoietic niche in immunodeficient mice: opportunities for studying primary multiple myeloma

Reconstructing the Human Hematopoietic Niche: Opportunities for Studying Normal and Malignant Hematopoiesis,

Migration Potential of Human Mesenchymal Stromal Cells Is Determined by Origin of Tissue Rather Than Their Developmental Stage

Colony Forming Unit-Endothelial Cells (CFU-EC) Are Derived from CD14 + Cells and Need Support by CD14 − Cells.

Amniotic fluid as a novel source of mesenchymal stem cells for therapeutic transplantation

Similar repopulating capacity of mitotically active and resting umbilical cord blood CD34 + cells in NOD/SCID mice

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American Society of Hematology

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American Society of Hematology

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