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Journal Articles

EHMT2 Inhibitor BIX-01294 Induces Endoplasmic Reticulum Stress Mediated Apoptosis and Autophagy in Diffuse Large B Cell Lymphoma Cells

Linyan Xu, PhD, Xiang Gao, Wei Sang, MD, Dongmei Yan, Xuguang Song, Feng Zhu, Kailin Xu, MD

Blood (2019) 134 (Supplement_1): 2787.

https://doi.org/10.1182/blood-2019-127653

Published: 2019

Journal Articles

A Novel PU.1 - Caspase 8/cFLIP Axis in Neutrophil and Macrophage Differentiation of AML Cells

Magali Humbert, PhD, Mario P. Tschan, PhD, Aladin Haimovici, Bruce E. Torbett, PhD, Nicolas Niklaus, MSc, BSc

Blood (2018) 132 (Supplement 1): 1347.

https://doi.org/10.1182/blood-2018-99-112797

Published: 2018

Journal Articles

Narciclasine Display Preferential Pre-Clinical Activity Against KSHV-Associated Primary Effusion Lymphoma By Targeting MYC Via NF-κB

Ramakrishnan Gopalakrishnan, PhD, Hittu Matta, PhD, Sunju Choi, PhD, Preet M. Chaudhary, MD PhD

Blood (2017) 130 (Supplement 1): 2807.

https://doi.org/10.1182/blood.V130.Suppl_1.2807.2807

Published: 2017

Journal Articles

The Long Form of Cellular FLIP Renders NK-Cell Lymphoma Cells Resistant to Fas-Mediated Apoptosis

Yasushi Isobe, MD, PhD, Azuchi Masuda, MD, Koichi Sugimoto, MD, PhD, Norio Komatsu, MD PhD

Blood (2016) 128 (22): 4129.

https://doi.org/10.1182/blood.V128.22.4129.4129

Published: 2016

Journal Articles

IMiD® Immunomodulatory Agents Promote Apoptosis in Multiple Myeloma Cells through Induction of TRAIL Expression

Michael D. Amatangelo, PhD, Chad C. Bjorklund, Anita K. Gandhi, PhD, Anke Klippel, Tom Daniel, Rajesh Chopra, MBBS, PhD, Matthew Trotter, Anjan Thakurta

Blood (2015) 126 (23): 5355.

https://doi.org/10.1182/blood.V126.23.5355.5355

Published: 2015

Journal Articles

Proapoptotic Bid Preserves HSC Function through Restraint of Necroptosis

Patrice N. Wagner, B.S., Qiong Shi, B.S., Yuri D. Fedoriw, MD, Sandra S. Zinkel, MD PhD

Blood (2014) 124 (21): 251.

https://doi.org/10.1182/blood.V124.21.251.251

Published: 2014

Journal Articles

AML Cells Utilize TNF-Driven JNK Signaling As a Critical NF-κB-Independent Survival Signal

Andrew Volk, Jing Li, PhD, Junping Xin, PhD, Dewen You, PhD, Jun Zhang, PhD, Peter Breslin, PhD, Zejuan Li, MD, PhD, Wei Wei, Rachel Schmidt, Xinyu Li, MD, Zhou Zhang, PhD, Paul C Kuo, MD, Sucha Nand, MD, Jianke Zhang, PhD, Jianjun Chen, PhD, Jiwang Zhang, MD, PhD

Blood (2013) 122 (21): 2890.

https://doi.org/10.1182/blood.V122.21.2890.2890

Published: 2013

Journal Articles

Histone 3 Methyltransferase (EZH2) Inhibition Enhances TRAIL-Induced Apoptosis In Mantle Cell Lymphoma Cells By Accelerated cFLIP Degradation

Frank K Braun, PhD, Rohit Mathur, PhD, Lalit Sehgal, Ph.D, Zuzana Berkova, PhD, Felipe Samaniego, M.D., M.P.H

Blood (2013) 122 (21): 4425.

https://doi.org/10.1182/blood.V122.21.4425.4425

Published: 2013

Journal Articles

The Role Of BIN1 Tumor Suppressor Isoforms In Regulation Of Proliferation, Apoptosis and Tumor Formation Of Human Cutanous T-Cell Lymphoma Cells In Vitro and In Vivo

Sharmin Esmailzadeh, Youwen Zhou, Xiaoyan Jiang, MD, PhD

Blood (2013) 122 (21): 2517.

https://doi.org/10.1182/blood.V122.21.2517.2517

Published: 2013

Journal Articles

Mechanism of Regulating Fas Signaling by Promyelocytic Leukemia Protein (PML) and Its Dominant-Negative Mutant PMLRARα

Rong-Hua Tao, M.D., Ph.D., Zuzana Berkova, PhD, Jillian F Wise, B.S., Haifeng Zhu, Ph.D., Xue Ao, MS, Zeming Chen, PhD, Wenzhuo Zhuang, PhD, Frank K Braun, PhD, Rohit Mathur, PhD, Felipe Samaniego, M.D.

Blood (2012) 120 (21): 1327.

https://doi.org/10.1182/blood.V120.21.1327.1327

Published: 2012

Journal Articles

Collateral Damage of Non-Hematopoietic Tissue by Hematopoiesis-Specific T Cells Results in GvHD During An Ongoing Profound Gvl Reaction,

Boris van der Zouwen, MD, Alwine Kruisselbrink, J.H. Frederik Falkenburg, Inge Jedema, PhD

Blood (2011) 118 (21): 4031.

https://doi.org/10.1182/blood.V118.21.4031.4031

Published: 2011

Journal Articles

PML and PMLRARα Interact with Fas to Regulate Fas-Mediated Apoptosis In Vivo

Felipe Samaniego, MD, Zuzana Berkova, PhD, Jillian F Wise, BS, Celine Kerros, PhD, David H Hawke, PhD, Judith E. Karp, MD, Hui-Kuan Lin, PhD, Jeffrey J. Molldrem, MD, Rong-Hua Tao, MD, PhD

Blood (2011) 118 (21): 2451.

https://doi.org/10.1182/blood.V118.21.2451.2451

Published: 2011

Journal Articles

Chronic Lymphocytic Leukemia: Proliferative and Apoptotic Profile on Lymph Node, Studied by Immunohistochemistry Including the Proliferation Centers

Sotirios P. Sachanas, MD, Georgia Levidou, MD, Maria K. Angelopoulou, Maria Moschogiannis, MD, Xanthi Yiakoumis, MD, Theodoros P. Vassilakopoulos, Flora Kontopidou, Christina H. Kalpadakis, MD, Pantelis Tsirkinidis, Aglaia Dimitrakopoulou, Styliani Kokoris, Panayiotis Panayiotidis, Helen A. Papadaki, Eustratios Patsouris, Penelope Korkolopoulou, Gerassimos Pangalis

Blood (2011) 118 (21): 2538.

https://doi.org/10.1182/blood.V118.21.2538.2538

Published: 2011

Journal Articles

MiR-146a up-Regulation Is Associated with Anti-Tumor Activity of Pan-Histone Deacetylase Inhibitor ITF2357 (Givinostat®) in Human Burkitt's Lymphoma

Roberta Zappasodi, PhD, Alessandra Cavanè, Marilena V Iorio, Monica Tortoreto, Giusi Ruggiero, Michele Magni, MD, Carmelo Carlo-Stella, MD, Elda Tagliabue, Franco Zunino, Carlo M. Croce, MD, Alessandro M. Gianni, MD, Massimo Di Nicola, MD

Blood (2011) 118 (21): 2729.

https://doi.org/10.1182/blood.V118.21.2729.2729

Published: 2011

Journal Articles

PDGF-RTK Inhibition Restores CD95/Fas-Mediated Apoptosis in Leukemic T-LGL Via Promoting ASM Translocation, Ceramide Production and CD95 Signal Amplification

Jun Yang, M.D., Yongping Li, M.D., Thomas P. Loughran, Jr., M.D.

Blood (2011) 118 (21): 1374.

https://doi.org/10.1182/blood.V118.21.1374.1374

Published: 2011

Journal Articles

Potentiation of bortezomib's Anti-Myeloma Effects in Combination with Anti-DR5 Agonistic Antibody: The Role of ER Stress in DR5 Editing and DR-Mediated Apoptotic Signaling

Hirokazu Miki, MD, Masahiro Abe, MD, PhD, Kumiko Kagawa, MD, Asuka Oda, PhD, Hiroe Amou, PhD, Akishige Ikegame, PhD, Keiichiro Watanabe, DDS, Masahiro Hiasa, DDS, Takeshi Harada, MD, Shiro Fujii, MD, Shingen Nakamura, MD, Ayako Nakano, MD, PhD, Kyoko Takeuchi, MD, PhD, Shuji Ozaki, MD, PhD, Yukimasa Shiotsu, PhD, Masaki Ri, MD, Shinsuke Iida, MD, PhD, Toshio Matsumoto, MD, PhD

Blood (2011) 118 (21): 5104.

https://doi.org/10.1182/blood.V118.21.5104.5104

Published: 2011

Journal Articles

Proteasome Inhibitors Sensitize Myeloma Cells to T Cell-Mediated Killing

Niels W.C.J. van de Donk, MD, PhD, Henk M. Lokhorst, MD, Maarten Emmelot, Tineke Aarts-Riemens, Douglas W. McMillin, PhD, Gullu Gorgun, PhD, Steffen Klippel, PhD, Eugen Dhimolea, PhD, Jana Jakubikova, PhD, Catriona A. Hayes, MD, Panisinee Lawasut, MD, Jake E Delmore, Nikhil C. Munshi, MD, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Constantine S. Mitsiades, MD, PhD, Tuna Mutis, MD PhD

Blood (2011) 118 (21): 1838.

https://doi.org/10.1182/blood.V118.21.1838.1838

Published: 2011

Journal Articles

hsTRAIL/Apo2L Induces Apoptosis in Enteropathy-Associated T-Cell Lymphoma

Marijn Radersma, MD, Laura R de Baaij, MD, Nathalie J Hijmering, Gert Ossenkoppele, MD, PhD, Chris JLM Meijer, MD, PhD, Chris JJ Mulder, MD, PhD, Saskia AGM Cillessen, PhD

Blood (2011) 118 (21): 1665.

https://doi.org/10.1182/blood.V118.21.1665.1665

Published: 2011

Journal Articles

PMLRARα binds to Fas and suppresses Fas-mediated apoptosis through recruiting c-FLIP in vivo

Rong-Hua Tao, Zuzana Berkova, Jillian F. Wise, Abdol-Hossein Rezaeian, Urszula Daniluk, Xue Ao, David H. Hawke, Judith E. Karp, Hui-Kuan Lin, Jeffrey J. Molldrem, Felipe Samaniego

Blood (2011) 118 (11): 3107–3118.

https://doi.org/10.1182/blood-2011-04-349670

Published: 2011

Includes: Supplemental data

Journal Articles

Regulation of steady-state neutrophil homeostasis by macrophages

Claire Gordy, Heather Pua, Gregory D. Sempowski, You-Wen He

Blood (2011) 117 (2): 618–629.

https://doi.org/10.1182/blood-2010-01-265959

Published: 2011

Includes: Supplemental data

NARROW

EHMT2 Inhibitor BIX-01294 Induces Endoplasmic Reticulum Stress Mediated Apoptosis and Autophagy in Diffuse Large B Cell Lymphoma Cells

A Novel PU.1 - Caspase 8/cFLIP Axis in Neutrophil and Macrophage Differentiation of AML Cells

Narciclasine Display Preferential Pre-Clinical Activity Against KSHV-Associated Primary Effusion Lymphoma By Targeting MYC Via NF-κB

The Long Form of Cellular FLIP Renders NK-Cell Lymphoma Cells Resistant to Fas-Mediated Apoptosis

IMiD® Immunomodulatory Agents Promote Apoptosis in Multiple Myeloma Cells through Induction of TRAIL Expression

Proapoptotic Bid Preserves HSC Function through Restraint of Necroptosis

AML Cells Utilize TNF-Driven JNK Signaling As a Critical NF-κB-Independent Survival Signal

Histone 3 Methyltransferase (EZH2) Inhibition Enhances TRAIL-Induced Apoptosis In Mantle Cell Lymphoma Cells By Accelerated cFLIP Degradation

The Role Of BIN1 Tumor Suppressor Isoforms In Regulation Of Proliferation, Apoptosis and Tumor Formation Of Human Cutanous T-Cell Lymphoma Cells In Vitro and In Vivo

Mechanism of Regulating Fas Signaling by Promyelocytic Leukemia Protein (PML) and Its Dominant-Negative Mutant PMLRARα

Collateral Damage of Non-Hematopoietic Tissue by Hematopoiesis-Specific T Cells Results in GvHD During An Ongoing Profound Gvl Reaction,

PML and PMLRARα Interact with Fas to Regulate Fas-Mediated Apoptosis In Vivo

Chronic Lymphocytic Leukemia: Proliferative and Apoptotic Profile on Lymph Node, Studied by Immunohistochemistry Including the Proliferation Centers

MiR-146a up-Regulation Is Associated with Anti-Tumor Activity of Pan-Histone Deacetylase Inhibitor ITF2357 (Givinostat®) in Human Burkitt's Lymphoma

PDGF-RTK Inhibition Restores CD95/Fas-Mediated Apoptosis in Leukemic T-LGL Via Promoting ASM Translocation, Ceramide Production and CD95 Signal Amplification

Potentiation of bortezomib's Anti-Myeloma Effects in Combination with Anti-DR5 Agonistic Antibody: The Role of ER Stress in DR5 Editing and DR-Mediated Apoptotic Signaling

Proteasome Inhibitors Sensitize Myeloma Cells to T Cell-Mediated Killing

hsTRAIL/Apo2L Induces Apoptosis in Enteropathy-Associated T-Cell Lymphoma

PMLRARα binds to Fas and suppresses Fas-mediated apoptosis through recruiting c-FLIP in vivo

Regulation of steady-state neutrophil homeostasis by macrophages

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