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Journal Articles

Targeting myeloid-cell specific integrin α9β1 inhibits arterial thrombosis in mice

Brief Report
Nirav Dhanesha, Manasa K. Nayak, Prakash Doddapattar, Manish Jain, Gagan D. Flora, Shigeyuki Kon, Anil K. Chauhan
Journal: Blood
Blood (2020) 135 (11): 857–861.
https://doi.org/10.1182/blood.2019002846
Published: 2020
Includes: Supplemental data
Journal Articles

Megakaryocyte Reprogramming in Breast Cancer

Harvey G. Roweth, BSc, PhD, Michael Malloy, BS, Gregory Goreczny, BS, PhD, Kelly E. Johnson, BS, PhD, Sandra S. McAllister, PhD, Joseph E. Italiano, Jr., BS, PhD, Elisabeth Battinelli, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 12.
https://doi.org/10.1182/blood-2019-124894
Published: 2019
Journal Articles

Targeting Myeloid-Cell Specific Integrin α9β1 Inhibits Arterial Thrombosis in Mice

Nirav Dhanesha, PhD, Manasa K Nayak, PhD, Prakash Doddapattar, PhD, Anil K Chauhan, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3581.
https://doi.org/10.1182/blood-2019-127006
Published: 2019
Journal Articles

Long Term Responses to Venetoclax and Ibrutinib in Mantle Cell Lymphoma Are Associated with Immunological Recovery and Prognostic Changes in Inflammatory Biomarkers

Joanne Davis, PhD, Sasanka M Handunnetti, MBBS, Chia Sharpe, Gillian Turner, Mary Ann Anderson, MBBS, PhD FRACP, FRCPA, Andrew W. Roberts, MBBS, PhD, John F. Seymour, MBBS, PhD FRACP, Constantine S. Tam, MBBS, MD, David Ritchie, MD PhD, Rachel Koldej
Journal: Blood
Blood (2019) 134 (Supplement_1): 2791.
https://doi.org/10.1182/blood-2019-122974
Published: 2019
Journal Articles

Aberrant Cathepsin S Induces a Supportive Immune Microenvironment in Follicular Lymphoma

Johannes Adrian Hildebrand, MSc, BSc, Deepak Bararia, Sebastian Stolz, Sarah Haebe, MD, Stefan Alig, Michael Bartoschek, Michael Boesl, Alessandro Pastore, Erik Gaitzsch, Michael Heide, Vindi Jurinovic, MSc, Monika Szczepanowski, Wolfram Klapper, Abner Louissaint, Jr., MD PhD, Christina Ludwig, Sebastian Bultmann, Heinrich Leonhardt, Sebastian Eustermann, Karl-Peter Hopfner, Wolfgang Hiddemann, MD PhD, Michael von Bergwelt, Christian Steidl, MD, Robert Kridel, MDMPH,PhD, David M Weinstock, Marc Schmidt-Supprian, Menyhárt B Sárosi, Verena Passerini, Josef Mautner, Oliver Weigert
Journal: Blood
Blood (2019) 134 (Supplement_1): 657.
https://doi.org/10.1182/blood-2019-122663
Published: 2019
Journal Articles

Meta-Analysis Illustrates Role of Interferon-γ Signaling in Multiple Myeloma Pathogenesis

Jihad Aljabban, MMSc, BA, Nabeal Aljabban, BS, Mohamad Mukhtar, BS, Saad Syed, BS, Ross Wanner, BS, Francesca Cottini, MD, Tiffany Hughes, BS, PhD, Kareem Saleh, BS, Evan C Catton, Taylor Gonzalez, Maryam Panahiazar, PhD, Dexter Hadley, MD PhD, Don M. Benson, Jr., MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4510.
https://doi.org/10.1182/blood-2018-99-112265
Published: 2018
Journal Articles

Pembrolizumab Enhances the Anti-Leukemia Activity of Antigen Specific Cytotoxic T Lymphocytes

Mao Zhang, MPH, Pariya Sukhumalchandra, BS, Anne V. Philips, PhD, Na Qiao, PhD, Celine Kerros, PhD, Lisa St. John, PhD, Alexander A. Perakis, BS, Karen Clise-Dwyer, PhD, Elizabeth Mittendorf, MD PhD, Naval G. Daver, MD, Jeffrey J. Molldrem, MD, Qing Ma, PhD, Gheath Alatrash, DO, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4542.
https://doi.org/10.1182/blood-2018-99-114864
Published: 2018
Journal Articles

High-Throughput Mirna Analysis Suggests Pro-Inflammatory Profile in Sickle Cell Disease

Matthew Cannon, BA, Sarah Glass, Sidney Smith, Melanie Heinlein, Rosa Lapalombella, PhD, Payal C Desai, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1077.
https://doi.org/10.1182/blood-2018-99-110812
Published: 2018
Journal Articles

Expression of the Tumor Suppressor WT1 Is Induced By PML-Rara in Acute Promyelocytic Leukemia. Â

Matt Christopher, MD PhD, Andrew Menssen, Margery Gang, Anand Upadhyaya, Lukas D Wartman, MD, Timothy James J Ley, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2508.
https://doi.org/10.1182/blood.V130.Suppl_1.2508.2508
Published: 2017
Journal Articles

Cathepsin G Is Expressed By B Cell Acute Lymphoblastic Leukemia and Is an Effective Immunotherapeutic Target

Maliha Khan, Selena Carmona, MS, Pariya Sukhumalchandra, Yihua Qiu, Alexander Perakis, Mao Zhang, MPH, Madhushree Zope, Anne Philip, Abdul Shah, Na Qiao, Lisa St. John, Jonathan Goldberg, Elizabeth Mittendorf, Jeffrey J. Molldrem, MD, Steven Kornblau, MD, Gheath Alatrash, DO, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1438.
https://doi.org/10.1182/blood.V130.Suppl_1.1438.1438
Published: 2017
Journal Articles

Blocking of Transient Receptor Potential Vanilloid1 (TRPV1) Promotes Lysosomal Destabilization and Enhances Bortezomib-Induced ER Stress and Cell Death Via HSP70 and LAMP3 Down-Regulation: Novel Therapeutic Target for Multiple Myeloma

Katia Beider, Valeria Voevoda, Hanna Bitner, Evgenia Rosenberg, Yaarit Sirovsky, Hila Magen, MD, Olga Ostrovsky, PhD, Avichai Shimoni, MD, Zohar Bromberg, PhD, Amnon Peled, Arnon Nagler, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 804.
https://doi.org/10.1182/blood.V130.Suppl_1.804.804
Published: 2017
Journal Articles

Identification of Myeloperoxidase As a Leukemia-Associated Antigen and Therapeutic Target for Acute Myeloid Leukemia

Eran Tallis, Sijie Lu, PhD, Xiaoling Ding, Dan Li, PhD, Kathryn Ruisaard, M. James You, MD PhD, Lisa St. John, Gheath Alatrash, DO, PhD, Qing Ma, PhD, Jeffrey J. Molldrem, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4460.
https://doi.org/10.1182/blood.V130.Suppl_1.4460.4460
Published: 2017
Journal Articles

Activation of Autophagy in Models of SF3B1 Mutant MDS

Valeria Visconte, PhD, Vera Adema, PhD, Bartlomiej P. Przychodzen, MSc, Allison Noe, Rachel Toth, Yasmine Hirbawi, Cassandra M. Hirsch, BS, Jack Khouri, MD, Elise LeMelle, BS, Suresh K. Balasubramanian, MD, Hetty E. Carraway, MD MBA, Daniel Lindner, MD PhD, Anjali S. Advani, MD, Heesun J. Rogers, MD PhD, James G Phillips, PhD, Tomas Radivoyevitch, Kevin R Kelly, MD PhD, Steffan T. Nawrocki, PhD, Mikkael A. Sekeres, MD MS, Jaroslaw P. Maciejewski, PhD MD FACP, Jennifer Carew, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4230.
https://doi.org/10.1182/blood.V130.Suppl_1.4230.4230
Published: 2017
Journal Articles

Phase 1 Clinical Safety, Pharmacokinetics (PK), and Activity of Apilimod Dimesylate (LAM-002A), a First-in-Class Inhibitor of Phosphatidylinositol-3-Phosphate 5-Kinase (PIKfyve), in Patients with Relapsed or Refractory B-Cell Malignancies

Wael A Harb, MD, Catherine S Diefenbach, MD, Nehal Lakhani, MD PhD, Sarah C Rutherford, MD, Marshall T Schreeder, MD, Stephen M Ansell, MD PhD, Taimur Sher, MD, David M Aboulafia, MD, Jonathon B Cohen, MDMS, Darrell Nix, BS, PhD, Sean Landrette, PhD, Kate Flanders, BS, Langdon L Miller, MD, Henri Lichenstein, PhD, Jeremy S. Abramson, MD MMSc
Journal: Blood
Blood (2017) 130 (Supplement 1): 4119.
https://doi.org/10.1182/blood.V130.Suppl_1.4119.4119
Published: 2017
Journal Articles

Targeting Autophagy in Myelodysplastic Syndromes

Valeria Visconte, PhD, Steffan T. Nawrocki, PhD, Bartlomiej P Przychodzen, MSc, Kevin R. Kelly, MD PhD, Mei Yin, Yvonne Parker, Michael J. Clemente, M.S., John Barnard, PhD, Anjali S. Advani, MD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Daniel Lindner, Heesun J Rogers, MD PhD, Jaroslaw P Maciejewski, MD PhD FACP, Jennifer S. Carew, PhD
Journal: Blood
Blood (2016) 128 (22): 4295.
https://doi.org/10.1182/blood.V128.22.4295.4295
Published: 2016
Journal Articles

hLL2-Cys-PBD, a New Site-Specifically Conjugated, Pyrrolobenzodiazepine (PBD) Dimer-Based Antibody Drug Conjugate (ADC) Targeting CD22-Expressing B-Cell Malignancies.

Francesca Zammarchi, PhD, Simon Corbett, Lauren Adams, Maria Mellinas-Gomez, PhD, Peter Tyrer, PhD, Sandamali Dissanayake, Simone Sims, Karin Havenith, PhD, Simon Chivers, PhD, David G Willimas, PhD, Philip W Howard, PhD, John A. Hartley, PhD, Patrick van Berkel, PhD
Journal: Blood
Blood (2016) 128 (22): 4176.
https://doi.org/10.1182/blood.V128.22.4176.4176
Published: 2016
Journal Articles

Hemopoietic Progenitor Cells from the Bone Marrow of Serpinb3A-/- Mice Are Radioresistant

Stephanie Thermozier, Michael W. Epperly, PhD, Darcy Franicola, Xichen Zhang, Renee Fisher, Donna Shields, Hong Wang, John A. Willis, Cliff Luke, Gary A. Silverman, Joel S. Greenberger, MD
Journal: Blood
Blood (2016) 128 (22): 2680.
https://doi.org/10.1182/blood.V128.22.2680.2680
Published: 2016
Journal Articles

Lysosomal Cell Death and Apoptosis Crosstalk - Synergistic Role in Bcl-2 Inhibitor (ABT-263) Mediated Cell Death in B-Cell Precursor Acute Lymphoblastic Leukemia

Stefanie Enzenmüller, PhD, Qian Sun, PhD, Klaus-Michael Debatin, MD PhD, Lüder-Hinrich Meyer, MD
Journal: Blood
Blood (2016) 128 (22): 1584.
https://doi.org/10.1182/blood.V128.22.1584.1584
Published: 2016
Journal Articles

Interferon Gamma (IFNγ)/STAT1 Signaling in Host Antigen Present Cells Suppresses MHC Class II-Dependent Presentation of Self-Antigens and Development of Graft Versus Host Disease (GVHD)

Caisheng Lu, MD PhD, Huihui Ma, MD, PhD, Liangsong Song, MD, PhD, Shirong Li, PhD, Suzanne Lentzsch, MD PhD, Markus Y Mapara, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2147.
https://doi.org/10.1182/blood.V128.22.2147.2147
Published: 2016
Journal Articles

Regulation of the Erythroid Iron Deprivation Response By a TfR2-Scribble-Epor Integrated Module Coupling Iron Sensing with Receptor Presentation

Shadi Khalil, MS, Lorrie L Delehanty, BS, Maja Holy, BS, Stephen Grado, BS, Grant C. Bullock, MD PhD, Adam Goldfarb, MD
Journal: Blood
Blood (2016) 128 (22): 3615.
https://doi.org/10.1182/blood.V128.22.3615.3615
Published: 2016