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Journal Articles

Cell Adhesion of ALL to Stromal Cells May Mediate CAR T-Cell Resistance: A Novel Escape Mechanism for Immunotherapy

Hye Na Kim, Enzi Jiang, MD PhD, Ruan Yongsheng, MD, Heather Ogana, Nour Abdel-Azim, Justin Le, BS, Annie Luong, Halvard Bonig, MD, Nabil Ahmed, MD, Moghimi Babak, MD, Michael A. Pulsipher, MD, Deepa Bhojwani, MD, Alan S. Wayne, MD, Chintan Parekh, MBBS, Hisham Abdel-Azim, Nora Heisterkamp, Yong-Mi Kim, MD MPH, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2623.
https://doi.org/10.1182/blood-2019-132131
Published: 2019
Journal Articles

Comprehensive Transcriptome Profiling of Cryptic CBFA2T3-GLIS2 Fusion-Positive AML Defines Novel Therapeutic Options — a COG and Target Pediatric AML Study

Jenny L. Smith, MSc, MD, Rhonda E. Ries, MA, Marianne T. Santaguida, BSc, PhD, Christos Gekas, PhD, Todd A Alonzo, PhD, Robert B Gerbing, MA, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, E. Anders Kolb, MD, Tiffany Hylkema, BS, Lisa Eidenschink Brodersen, PhD, Michael R. Loken, PhD, Hamid Bolouri, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 881.
https://doi.org/10.1182/blood-2018-99-115544
Published: 2018
Journal Articles

Comparison of the Transcriptomic Signature of Pediatric Vs. Adult CML and Normal Bone Marrow Stem Cells

Hee-Don Chae, PhD, Lara C. Murphy, MD, Michele Donato, PhD, Alex G. Lee, PhD, E. Alejandro Sweet-Cordero, MD PhD, Parveen Abidi, PhD, Henrique Bittencourt, MD PhD, Norman J. Lacayo, MD, Gary Van Houten Dahl, MD, Catherine Aftandilian, MD, Kara L. Davis, DO, Min Huang, PhD, Nathan Sumarsono, BS, Michele Redell, MD PhD, Cecilia H. Fu, MD, I-Ming L. Chen, DVM, MS, Todd A Alonzo, PhD, Elizabeth A. Eklund, MD, Jason R. Gotlib, MD MS, Purvesh Khatri, PhD, Nobuko Hijiya, MD, Kathleen M. Sakamoto, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4246.
https://doi.org/10.1182/blood-2018-99-119974
Published: 2018
Journal Articles

Epigenetic Drug Combination Chemo-Sensitizes Pediatric AML By Reducing Cell Adhesion and Dislodging AML Cells from the Bone Marrow

Samantha Weber, BS, Anilkumar Gopalakrisnapillai, PhD, E. Anders Kolb, MD, Sonali Barwe, PhD MSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 2637.
https://doi.org/10.1182/blood-2018-99-120321
Published: 2018
Journal Articles

Characteristic Amino Acid and Energy Metabolism in AML Stem Cells As Revealed By Quantitative Multiplex Proteomics

Simon Raffel, MD, Jenny Hansson, Mattia Falcone, Christoph Lutz, Oliver Bischel, MD, Anthony D Ho, Jeroen Krijgsveld, Andreas Trumpp, Prof, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2780.
https://doi.org/10.1182/blood-2018-99-117046
Published: 2018
Journal Articles

Inhibition of B-Cell Receptor Signaling Disrupts Cell Adhesion in Mantle Cell Lymphoma Via RAC2

Weige Wang, MD, Franzen Carrie, Hui Guo, PhD, Jimmy Lee, MD, Yan Li, Madina Sukhanova, PhD, Dong Sheng, MD, Girish Venkataraman, MD MBBS, Ming Mei, Pin Lu, PhD, Anhui Gao, Chunmei Xia, Li Jia, Liang Zhang, MD PhD, Michael Wang, MD, Jorge Andrade, Zhou Xiaoyan, Y. Lynn Lynn Wang, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1369.
https://doi.org/10.1182/blood-2018-99-118598
Published: 2018
Journal Articles

Loss of miR-199b Impairs Active Cycling of Hematopoietic Stem Cells during Steady-State Hematopoiesis

Aldona A Karaczyn, Edward Jachimowicz, Jaspreet S Kohli, Pradeep Sathyanarayana
Journal: Blood
Blood (2018) 132 (Supplement 1): 1283.
https://doi.org/10.1182/blood-2018-99-116381
Published: 2018
Journal Articles

Proteomic and Biological Analysis of Myeloma Cell Derived Extracellular Vesicles

Dominique B Hoelzinger, PhD, Sophia J Quinton, Denise K Walters, PhD, Renee C Tschumper, Diane F Jelinek, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5605.
https://doi.org/10.1182/blood-2018-99-116926
Published: 2018
Journal Articles

Combining Next Generation Proteomics Platforms with Drug Sensitivity Resistance Testing Allows Identification of Physiologically Distinct Sub-Clones That Can Inform Therapeutic and Drug Development Strategies

Despina Bazou, BSc, MSc, PhD, Muntasir M Majumder, MSc, BPharm, Ciara Tierney, BSc, Sinead O'Rourke, BSc, Pekka Anttila, MD, Raija Helena Silvennoinen, MD PhD, Caroline A Heckman, PhD, Paul Dowling, BSc, PhD, Peter O'Gorman, MD PhD FRCP, FRCPath
Journal: Blood
Blood (2018) 132 (Supplement 1): 1901.
https://doi.org/10.1182/blood-2018-99-115910
Published: 2018
Journal Articles

Targeting Aberrant Expression of CD81 Impacts Cell Adhesion and Migration, Drug Resistance and Prognosis of Acute Myeloid Leukemia

Fanny Gonzales, Thomas Boyer, Pauline Peyrouze, Soizic Guihard, Christophe Roumier, Céline Berthon, MD PhD, Claude Preudhomme, PharmD, PhD, Meyling Cheok, BSPharm, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2675.
https://doi.org/10.1182/blood.V130.Suppl_1.2675.2675
Published: 2017
Journal Articles

Downregulation of MHC Class II in Relapsed AML Cells after Allogeneic Transplantation

Matt Christopher, MD PhD, Allegra A Petti, PhD, Christopher A. Miller, PhD, Michael P Rettig, PhD, Eric J. Duncavage, MD, Jeffery M. Klco, MD PhD, Nichole M Helton, Michelle O'Laughlin, Catrina Fronick, Robert Fulton, MS, Richard K. Wilson, Lukas D Wartman, MD, John S. Welch, MD PhD, Sharon E Heath, Jacqueline E. Payton, MDPhD, Timothy Aaron Graubert, MD, Daniel C. Link, MD, Matthew J. Walter, MD, Peter Westervelt, MDPhD, Timothy James J Ley, MD, John F DiPersio, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2678.
https://doi.org/10.1182/blood.V130.Suppl_1.2678.2678
Published: 2017
Journal Articles

Different Conformations of Fibronectin Fibrils Formed Under Cell-Free Condition in Vitro display Distinct Effects on Cell Adhesion and Spreading

Phong Le, Si Nguyen Mai Thu, Volker R. Stoldt, PhD, Toi Van Vo, Prof. Dr., Rudiger E. Scharf, Prof.Dr., Khon Huynh, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2307.
https://doi.org/10.1182/blood.V130.Suppl_1.2307.2307
Published: 2017
Journal Articles

Role of GATA2 in the Maintenance of the Bone Marrow Microenvironment

Shin Hasegawa, Tohru Fujiwara, MD PhD, Yoko Okitsu, MD PhD, Hiroki Kato, MD, PhD, Yuki Sato, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Kenichi Ishizawa, Ritsuko Shimizu, MD PhD, Masayuki Yamamoto, MD PhD, Hideo Harigae, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3781.
https://doi.org/10.1182/blood.V130.Suppl_1.3781.3781
Published: 2017
Journal Articles

Gene Expression Profile in Endothelial Cells: Effects of Defibrotide on Different Functional Pathways

Luciana Teofili, Nicoletta Orlando, Maria Grazia Iachininoto, Maria Bianchi, Caterina Giovanna Valentini, Simona Sica, MD, Giuseppe Leone, Valerio De Stefano
Journal: Blood
Blood (2017) 130 (Supplement 1): 4833.
https://doi.org/10.1182/blood.V130.Suppl_1.4833.4833
Published: 2017
Journal Articles

IFN-γ Induces Distinct Single Cell Transcriptomes in Clinical-Grade Mesenchymal Stromal Cells

Reema Panjwani, BS, Stefan Cordes, MD PhD, Zerick Terrell Dunbar, BS, MS, Jinguo Chen, MD, Prachi Jain, MD, Fariba Chinian, MS, Sara Hauffe, RN, Eleftheria Koklanaris, RN, Jeanine Superata, RN, Rongye Shi, MD, Huizhi Zhou, David Stroncek, MD, Nan Zhang, PhD, Sarah Davies, BS, Minoo Battiwalla, MD, Austin John Barrett, MD FRCP, FRCPath, Sawa Ito, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4472.
https://doi.org/10.1182/blood.V130.Suppl_1.4472.4472
Published: 2017
Journal Articles

A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemic Pathogenesis

Andrew Volk, PhD, Kaiwei Liang, PhD, Jianyun Zhao, Xinyu Li, Marinka Bulic, Stacy Marshall, Jeffrey W. Taub, MD, Yubin Ge, PhD, Sebastien Malinge, PhD, Elizabeth Bartom, PhD, Ali Shilatifard, PhD, John D. Crispino, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 245.
https://doi.org/10.1182/blood.V130.Suppl_1.245.245
Published: 2017
Journal Articles

Relapsing Pediatric T-Cell Acute Lymphoblastic Leukemia Downregulates T-Cell Properties and Upregulates Cell Adhesion

Paulina Richter-Pechanska, PhD, Joachim B. Kunz, MD, Tobias Rausch, Caroline Von Knebel Doeberitz, Viktoras Frismantas, MSc, Maria Pamela Dobay, PhD, Beat Bornhauser, PhD, Martin Zimmermann, PhD, Obul Reddy Bandapalli, PhD, Stephan Fuhrmann, MD, Elena Orlova, Sebastian Uhrig, Gnana Prakash Balasubramanian, Martin Stanulla, MD PhD, Martin Schrappe, MD PhD, Gunnar Cario, MD, Gabriele Escherich, MD, Kseniya Bakharevich, Renate Kirschner-Schwabe, PhD, Cornelia Eckert, PhD, Stefan Pfister, Jan O. Korbel, PhD, Martina Muckenthaler, Jean-Pierre Bourquin, MD PhD, Andreas E. Kulozik, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2726.
https://doi.org/10.1182/blood.V130.Suppl_1.2726.2726
Published: 2017
Journal Articles

RAC2 Links B-Cell Receptor Signaling and Cell Adhesion in Mantle Cell Lymphoma

Weige Wang, Franzen Carrie, Madina Sukhanova, Venkataraman Girish, Ming Mei, Guo Ailin, Pin Lu, PhD, Dong Sheng, MD, Gao Anhui, Xia Chunmei, Li Jia, Zhou Xiaoyan, Y Lynn Wang
Journal: Blood
Blood (2017) 130 (Supplement 1): 2752.
https://doi.org/10.1182/blood.V130.Suppl_1.2752.2752
Published: 2017
Journal Articles

SOX11 holds mantle cell lymphoma’s key to home

David Dominguez-Sola
Journal: Blood
Blood (2017) 130 (4): 389–391.
https://doi.org/10.1182/blood-2017-06-788448
Published: 2017
Journal Articles

Preclinical Development of a T-Cell ALL CAR Demonstrates That Differences in CAR Membrane Distribution May Impact Efficacy

Haneen Shalabi, DO, Haiying Qin, MS, Kelsey Wanhainen, BS, Jillian Smith, BS, Rimas Orentas, PhD, Nirali N Shah, MD, Shannon L Maude, MD PhD, Sarah K Tasian, MD, David T Teachey, MD, Javed Khan, MD, Terry J Fry, MD
Journal: Blood
Blood (2016) 128 (22): 4019.
https://doi.org/10.1182/blood.V128.22.4019.4019
Published: 2016