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Journal Articles

RhoA Targeting Suppresses Cold-Induced Platelet Lesion and Allows Refrigerated Storage of Functional Human Platelets to Fourteen Days

Shailaja N Hegde, PhD, Huzoor Akbar, PhD, Shawnagay Nestheide, BS, Ashley M Wellendorf, B.S., Breanna Bohan, James F Johnson, Yi Zheng, PhD, Jose A Cancelas, MD

Blood (2019) 134 (Supplement_1): 99.

https://doi.org/10.1182/blood-2019-125359

Published: 2019

Journal Articles

A Critical Role for the IKKβ/Lipid Rafts Axis in Regulating Platelet Exocytosis, Via the Spatial Regulation of SNARE Proteins

Zubair A Karim, PhD, Nicole R Hensch, BS, MS, Hanan Qasim, BPharm, Fatima Z Alshbool, PharmD, PhD, Fadi T. Khasawneh, BPharm, PhD

Blood (2017) 130 (Supplement 1): 3602.

https://doi.org/10.1182/blood.V130.Suppl_1.3602.3602

Published: 2017

Journal Articles

Pre-Clinical Study of Ibrutinib for the Treatment of T-Cell Lymphoma Using Magnetic Resonance Imaging (MRI) Assessment

Rebecca L Allchin, MRCP, MBBS, BSc, Michael E Kelly, PhD, Sami Mamand, Ruth C Barber, PhD, Matthew J Ahearne, MDMBBS, Simon D. Wagner, PhD FRCP

Blood (2017) 130 (Supplement 1): 4110.

https://doi.org/10.1182/blood.V130.Suppl_1.4110.4110

Published: 2017

Journal Articles

Inhibition of HIF Prolyl Hydroxylases Mitigate Gut Graft-Versus-Host Disease

Rena Feinman, PhD, Iriana Colorado, MSc, Keyi Wang, MSc, Eugenia Dziopa, MSc, Michael A Flynn, MSc, Kevin Peters, MD, Andrew L. Pecora, MD, Robert Korngold, PhD

Blood (2016) 128 (22): 3349.

https://doi.org/10.1182/blood.V128.22.3349.3349

Published: 2016

Journal Articles

Ixazomib, an Oral Proteasome Inhibitor, Induces Rapid Mobilization of Hematopoietic Stem Cells in Mice

Armin Ghobadi, MD, Michael P. Rettig, PhD, Matthew Holt, Julie Ritchey, Linda Eissenberg, John F. DiPersio, MD PhD

Blood (2015) 126 (23): 513.

https://doi.org/10.1182/blood.V126.23.513.513

Published: 2015

Journal Articles

Ptdglc-Enriched Lipid Rafts Are a Novel Platform for Apoptosis Signaling in Human Neutrophilic Lineage Cells

Roudy Chiminch Ekyalongo, Noriko Yokoyama, Hitoshi Nakayama, Hideoki Ogawa, Yoko Tabe, Kenji Takamori, Yoshio Hirabayashi, Kazuhisa Iwabuchi

Blood (2015) 126 (23): 4968.

https://doi.org/10.1182/blood.V126.23.4968.4968

Published: 2015

Journal Articles

SH2B3/LNK Loss of Function Promotes Atherosclerosis and Thrombosis

Wei Wang, MD, Yang Tang, MD, Ying Wang, MD PhD, Joanna Balcerek, PhD, Wei Tong, PhD, Ross L. Levine, MD, Carrie Welch, PhD, Alan Tall, MD, Nan Wang, PhD

Blood (2015) 126 (23): 3443.

https://doi.org/10.1182/blood.V126.23.3443.3443

Published: 2015

Journal Articles

Therapeutic Effects of MLN4924 on Sclerodermatous Chronic Graft Versus Host Disease

Chien-Chun Steven Pai, Mingyi Chen, MD PhD, Anthony E Zamora, Lam Khuat, Steven Grossenbacher, William J Murphy, PhD, Mehrdad Abedi, MD

Blood (2014) 124 (21): 3816.

https://doi.org/10.1182/blood.V124.21.3816.3816

Published: 2014

Journal Articles

Striatin Is a Novel Regulator Of Aldosterone-Mediated Endothelial Cell Activation

Enrique D. Machado-Fiallo, BS, Christopher Vega, MD, Arelys Ramos-Rivera, MD, Josue A. Benabe-Carlo, BS, Gregory N. Prado, PhD, Luminita H. Pojoga, PhD, Alicia Rivera, MS, PhD, Jose R. Romero, PhD

Blood (2013) 122 (21): 3523.

https://doi.org/10.1182/blood.V122.21.3523.3523

Published: 2013

Journal Articles

New Clues To The Mechanism Of Cardioprotection By Estrogen

Nishi H Patel, MD, R. Alan Mitteer, MS, Jamunabai M Prakash, MS, Oresta V Borodevyc, Gerald Soslau, PhD

Blood (2013) 122 (21): 4736.

https://doi.org/10.1182/blood.V122.21.4736.4736

Published: 2013

Journal Articles

Combined Therapy With BRD4 Antagonist and FLT3 Inhibitor Exerts Synergistic Activity Against Cultured and Primary AML Blast Progenitors Expressing FLT-ITD

Melissa Rodriguez, M.D., Ph.D, Warren Fiskus, Ph.D, Sunil Sharma, MD, Jun Qi, PhD, John A Valenta, M.S., Leasha J Schaub, M.S., Bhavin Shah, Santhana Devaraj, Ph.D, Swaminathan Padmanabhan Iyer, MD, James E Bradner, MD, Kapil N. Bhalla, MD

Blood (2013) 122 (21): 3821.

https://doi.org/10.1182/blood.V122.21.3821.3821

Published: 2013

Journal Articles

Combined Therapy With BRD4 Antagonist and JAK Inhibitor Is Synergistically Lethal Against Human Myeloproliferative Neoplasm (MPN) Cells

John A Valenta, M.S., Warren Fiskus, Ph.D, Taghi Manshouri, Ph.D., Sunil Sharma, MD, Jun Qi, PhD, Leasha J Schaub, M.S., Bhavin Shah, Melissa Rodriguez, M.D., Ph.D, Santhana Devaraj, Ph.D, Swaminathan Padmanabhan Iyer, MD, Srdan Verstovsek, MD, PhD, James E Bradner, MD, Kapil N. Bhalla, MD

Blood (2013) 122 (21): 2842.

https://doi.org/10.1182/blood.V122.21.2842.2842

Published: 2013

Journal Articles

Endothelial-Specific Knockdown Of Caveolin-1 Lowers Circulating Protein Disulfide Isomerase Levels and Is Associated With Changes In Erythrocyte Volume Homeostasis

Josue A. Benabe-Carlo, BS, Jose R Romero, PhD, Enrique D. Machado-Fiallo, BS, Arelys Ramos-Rivera, MD, Gregory N. Prado, PhD, Luminita H Pojoga, PhD, Alicia Rivera, MS, PhD

Blood (2013) 122 (21): 12.

https://doi.org/10.1182/blood.V122.21.12.12

Published: 2013

Journal Articles

The Endothelial Lectin Receptor CLEC4M Internalizes Factor VIII and Von Willebrand Factor Via a Clathrin-Coated Pit-Dependent Mechanism

Laura L. Swystun, PhD, Colleen Notley, Ilinca Georgescu, Paula D. James, MD, David Lillicrap, MD

Blood (2013) 122 (21): 1091.

https://doi.org/10.1182/blood.V122.21.1091.1091

Published: 2013

Journal Articles

BRD4 Antagonist and Histone Deacetylase Inhibitor: A Novel Synergistic Combination Against Human Acute Myeloid Leukemia (AML) Cells

Warren Fiskus, Ph.D, Sunil Sharma, MD, Jun Qi, PhD, John A Valenta, M.S., Leasha J Schaub, M.S., Bhavin Shah, Karissa Peth, Laxmi U.M.R. Jakkula, PhD, Melissa Rodriguez, M.D., Ph.D, Santhana Devaraj, Ph.D, Swaminathan Padmanabhan Iyer, MD, James E Bradner, MD, Kapil N. Bhalla, MD

Blood (2013) 122 (21): 485.

https://doi.org/10.1182/blood.V122.21.485.485

Published: 2013

Journal Articles

The 2 nd Generation Proteasome Inhibitor, MLN2238: Potent Induction of Cell Death in T-Cell Lymphoma (TCL) and Hodgkin Lymphoma (HL) Cell Lines and in Two Human Lymphoma Xenograft Models.

Ravi Dashnamoorthy, Ph.D., Irawati Kandela, Ph.D., Savita Bhalla, PhD, Jasmine Galloway, Irina Zaretsky, Andrew Mazar, Ph.D., Andrew M. Evens, DO, MSc

Blood (2012) 120 (21): 2767.

https://doi.org/10.1182/blood.V120.21.2767.2767

Published: 2012

Journal Articles

Antiproliferative Effect of 2-Hydroxypropyl-β-Cyclodextrin (HP-β-CyD) Against Chronic Myeloid Leukemia In Vitro and In Vivo .

Masako Yokoo, MD, Yasushi Kubota, MD, PhD, Sakiko Mochinaga, Aya Maeda, Tatsuo Ichinohe, MD, PhD, Hiroshi Fujito, Taishi Higashi, Keiichi Motoyama, Hidetoshi Arima, Tetsumi Irie, Shinya Kimura, MD, PhD

Blood (2012) 120 (21): 2442.

https://doi.org/10.1182/blood.V120.21.2442.2442

Published: 2012

Journal Articles

Phase IIa, Open-Label, Randomized, Pharmacokinetic Comparative, Cross-Over Study of Melphalan HCl for Injection (Propylene Glycol-Free) and Alkeran for Injection for Myeloablative Conditioning in Multiple Myeloma Patients Undergoing Autologous Transplantation

Omar S. Aljitawi, MD, Sunil Abhyankar, MD, Siddhartha Ganguly, MD, Karen Wolfe, Kelly Daniels, Ron Marks, Mike Ferree, J.D. Pipkin, PhD, Joseph McGuirk, DO

Blood (2011) 118 (21): 4512.

https://doi.org/10.1182/blood.V118.21.4512.4512

Published: 2011

Journal Articles

FLT3 Inhibitor AC220 Is a Potent Therapy for Myeloproliferative Disease in c-Cbl RING Finger Mutant Mice

Wallace Y Langdon, PhD, Samantha A Dagger, Samuel J Taylor, Christine B F Thien, PhD, Matthew E Wikstrom, PhD

Blood (2011) 118 (21): 642.

https://doi.org/10.1182/blood.V118.21.642.642

Published: 2011

Journal Articles

Linker of Activation of T Cells – 2 (LAT2), a Lipid Raft-Associated Adaptor Protein, Is a Novel Target for Therapy in Acute Leukemia

Guilherme A dos Santos, Carolina H Thomé, Germano Aguiar Ferreira, Priscila S Scheucher, Ph.D, Antonio R Lucena-Araujo, Kleber T de Oliveira, Hamilton L. Gimenes-Teixeira, Ph.D, Pietro Ciancaglini, Roberto P. Falcao, M.D., Ph.D, Lewis J Greene, Faça M Vitor, Eduardo M. Rego, M.D., Ph.D

Blood (2011) 118 (21): 737.

https://doi.org/10.1182/blood.V118.21.737.737

Published: 2011

NARROW

RhoA Targeting Suppresses Cold-Induced Platelet Lesion and Allows Refrigerated Storage of Functional Human Platelets to Fourteen Days

A Critical Role for the IKKβ/Lipid Rafts Axis in Regulating Platelet Exocytosis, Via the Spatial Regulation of SNARE Proteins

Pre-Clinical Study of Ibrutinib for the Treatment of T-Cell Lymphoma Using Magnetic Resonance Imaging (MRI) Assessment

Inhibition of HIF Prolyl Hydroxylases Mitigate Gut Graft-Versus-Host Disease

Ixazomib, an Oral Proteasome Inhibitor, Induces Rapid Mobilization of Hematopoietic Stem Cells in Mice

Ptdglc-Enriched Lipid Rafts Are a Novel Platform for Apoptosis Signaling in Human Neutrophilic Lineage Cells

SH2B3/LNK Loss of Function Promotes Atherosclerosis and Thrombosis

Therapeutic Effects of MLN4924 on Sclerodermatous Chronic Graft Versus Host Disease

Striatin Is a Novel Regulator Of Aldosterone-Mediated Endothelial Cell Activation

New Clues To The Mechanism Of Cardioprotection By Estrogen

Combined Therapy With BRD4 Antagonist and FLT3 Inhibitor Exerts Synergistic Activity Against Cultured and Primary AML Blast Progenitors Expressing FLT-ITD

Combined Therapy With BRD4 Antagonist and JAK Inhibitor Is Synergistically Lethal Against Human Myeloproliferative Neoplasm (MPN) Cells

Endothelial-Specific Knockdown Of Caveolin-1 Lowers Circulating Protein Disulfide Isomerase Levels and Is Associated With Changes In Erythrocyte Volume Homeostasis

The Endothelial Lectin Receptor CLEC4M Internalizes Factor VIII and Von Willebrand Factor Via a Clathrin-Coated Pit-Dependent Mechanism

BRD4 Antagonist and Histone Deacetylase Inhibitor: A Novel Synergistic Combination Against Human Acute Myeloid Leukemia (AML) Cells

The 2 nd Generation Proteasome Inhibitor, MLN2238: Potent Induction of Cell Death in T-Cell Lymphoma (TCL) and Hodgkin Lymphoma (HL) Cell Lines and in Two Human Lymphoma Xenograft Models.

Antiproliferative Effect of 2-Hydroxypropyl-β-Cyclodextrin (HP-β-CyD) Against Chronic Myeloid Leukemia In Vitro and In Vivo .

Phase IIa, Open-Label, Randomized, Pharmacokinetic Comparative, Cross-Over Study of Melphalan HCl for Injection (Propylene Glycol-Free) and Alkeran for Injection for Myeloablative Conditioning in Multiple Myeloma Patients Undergoing Autologous Transplantation

FLT3 Inhibitor AC220 Is a Potent Therapy for Myeloproliferative Disease in c-Cbl RING Finger Mutant Mice

Linker of Activation of T Cells – 2 (LAT2), a Lipid Raft-Associated Adaptor Protein, Is a Novel Target for Therapy in Acute Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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