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Journal Articles

Characterization of Type 2N Von Willebrand Disease Mutations Using Ιn Vitro and Ιn Vivo Mouse Models

Laura L Swystun, PhD, Ilinca Georgescu, Meghan Deforest, Mia Golder, PhD, Kate Sponagle, Christine Brown, Colleen Notley, David Lillicrap, MD

Blood (2014) 124 (21): 471.

https://doi.org/10.1182/blood.V124.21.471.471

Published: 2014

Journal Articles

Omental implantation of BOECs in hemophilia dogs results in circulating FVIII antigen and a complex immune response

Margareth C. Ozelo, Barbara Vidal, Christine Brown, Colleen Notley, Carol Hegadorn, Sandra Webster, Lori Harpell, James Ahlin, Andrew Winterborn, Janine Handforth, Valder R. Arruda, Christine Hough, David Lillicrap

Blood (2014) 123 (26): 4045–4053.

https://doi.org/10.1182/blood-2013-12-545780

Published: 2014

Includes: Supplemental data

Journal Articles

Regulation Of Factor VIII Clearance By Mannose-Binding Lectins

Laura L. Swystun, PhD, Colleen Notley, Kate Sponagle, Paula D. James, MD, David Lillicrap

Blood (2013) 122 (21): 2340.

https://doi.org/10.1182/blood.V122.21.2340.2340

Published: 2013

Journal Articles

The Endothelial Lectin Receptor CLEC4M Internalizes Factor VIII and Von Willebrand Factor Via a Clathrin-Coated Pit-Dependent Mechanism

Laura L. Swystun, PhD, Colleen Notley, Ilinca Georgescu, Paula D. James, MD, David Lillicrap, MD

Blood (2013) 122 (21): 1091.

https://doi.org/10.1182/blood.V122.21.1091.1091

Published: 2013

Journal Articles

The C-type lectin receptor CLEC4M binds, internalizes, and clears von Willebrand factor and contributes to the variation in plasma von Willebrand factor levels

Natalia Rydz, Laura L. Swystun, Colleen Notley, Andrew D. Paterson, J. Jacob Riches, Kate Sponagle, Boonchai Boonyawat, Robert R. Montgomery, Paula D. James, David Lillicrap

Blood (2013) 121 (26): 5228–5237.

https://doi.org/10.1182/blood-2012-10-457507

Published: 2013

Includes: Supplemental data

Journal Articles

Genetic Variability of the CLEC4M Endothelial Lectin Receptor Modulates Binding and Internalization of Von Willebrand Factor and Contributes to Variance in Plasma VWF Levels

Laura L. Swystun, PhD, Natalia Rydz, MD, Colleen Notley, Jonathan J. Riches, Andrew D Paterson, MD, Robert R. Montgomery, MD, Paula D. James, MD, David Lillicrap, MD

Blood (2012) 120 (21): 16.

https://doi.org/10.1182/blood.V120.21.16.16

Published: 2012

Journal Articles

Pathologic mechanisms of type 1 VWD mutations R1205H and Y1584C through in vitro and in vivo mouse models

Cynthia M. Pruss, Mia Golder, Andrea Bryant, Carol A. Hegadorn, Erin Burnett, Kimberly Laverty, Kate Sponagle, Aly Dhala, Colleen Notley, Sandra Haberichter, David Lillicrap

Blood (2011) 117 (16): 4358–4366.

https://doi.org/10.1182/blood-2010-08-303727

Published: 2011

Journal Articles

Functional characterization of a 13-bp deletion (c.-1522_-1510del13) in the promoter of the von Willebrand factor gene in type 1 von Willebrand disease

Maha Othman, Yvette Chirinian, Christine Brown, Colleen Notley, Nicholas Hickson, Daniel Hampshire, Suzanne Buckley, Simon Waddington, Alan L. Parker, Andrew Baker, Paula James, David Lillicrap

Blood (2010) 116 (18): 3645–3652.

https://doi.org/10.1182/blood-2009-12-261131

Published: 2010

Journal Articles

In Vitro and In Vivo Mouse Models of the Type 1 Von Willebrand Disease Mutations Y1584C and R1205H.

Cynthia M. Pruss, BSc, Kate Sponagle, Kimberly Laverty, Carol A. Hegadorn, Yvette Chirinian, Colleen Notley, Mia Golder, David Lillicrap, MD

Blood (2009) 114 (22): 26.

https://doi.org/10.1182/blood.V114.22.26.26

Published: 2009

Journal Articles

The mutational spectrum of type 1 von Willebrand disease: results from a Canadian cohort study

Paula D. James, Colleen Notley, Carol Hegadorn, Jayne Leggo, Angie Tuttle, Shawn Tinlin, Christine Brown, Chandler Andrews, Andrea Labelle, Yvette Chirinian, Lee O'Brien, Maha Othman, Georges Rivard, Dilys Rapson, Christine Hough, David Lillicrap, for the Association of Hemophilia Clinic Directors of Canada

Blood (2006) 109 (1): 145–154.

https://doi.org/10.1182/blood-2006-05-021105

Published: 2006

Journal Articles

Identification and functional characterization of a novel 27-bp deletion in the macroglycopeptide-coding region of the GPIBA gene resulting in platelet-type von Willebrand disease

Maha Othman, Colleen Notley, Frances Louise Lavender, Helen White, Christopher D. Byrne, David Lillicrap, Denise Frances O'Shaughnessy

Blood (2005) 105 (11): 4330–4336.

https://doi.org/10.1182/blood-2002-09-2942

Published: 2005

Journal Articles

Cell type–specific regulation of von Willebrand factor expression by the E4BP4 transcriptional repressor

Christine Hough, Carla D. Cuthbert, Colleen Notley, Christine Brown, Carol Hegadorn, Ergul Berber, David Lillicrap

Blood (2005) 105 (4): 1531–1539.

https://doi.org/10.1182/blood-2002-10-3093

Published: 2005

Journal Articles

Identification and Functional Characterization of a Novel 27bp Deletion in the Macroglycopeptide-Coding Region of the GPIbα Gene Resulting in Platelet-Type Von Willebrand Disease.

Maha Othman, MD, PhD, Hisham S. Elbatarny, MD, MSc, Colleen Notley, Louise F. Lavender, PhD, Helen White, PhD, Christopher D. Byrne, FRCP, FRCPath, PhD, Denise F. O’Shaughnessy, FRCP, FRCPath, PhD, MBA, David P. Lillicrap, MD, FRCPC, PhD

Blood (2004) 104 (11): 1023.

https://doi.org/10.1182/blood.V104.11.1023.1023

Published: 2004

Journal Articles

Systemic delivery of an adenoviral vector encoding canine factor VIII results in short-term phenotypic correction, inhibitor development, and biphasic liver toxicity in hemophilia A dogs

Angela M. Gallo-Penn, Pamela S. Shirley, Julie L. Andrews, Shawn Tinlin, Sandy Webster, Cherie Cameron, Christine Hough, Colleen Notley, David Lillicrap, Michael Kaleko, Sheila Connelly

Blood (2001) 97 (1): 107–113.

https://doi.org/10.1182/blood.V97.1.107

Published: 2001

NARROW

Characterization of Type 2N Von Willebrand Disease Mutations Using Ιn Vitro and Ιn Vivo Mouse Models

Omental implantation of BOECs in hemophilia dogs results in circulating FVIII antigen and a complex immune response

Regulation Of Factor VIII Clearance By Mannose-Binding Lectins

The Endothelial Lectin Receptor CLEC4M Internalizes Factor VIII and Von Willebrand Factor Via a Clathrin-Coated Pit-Dependent Mechanism

The C-type lectin receptor CLEC4M binds, internalizes, and clears von Willebrand factor and contributes to the variation in plasma von Willebrand factor levels

Genetic Variability of the CLEC4M Endothelial Lectin Receptor Modulates Binding and Internalization of Von Willebrand Factor and Contributes to Variance in Plasma VWF Levels

Pathologic mechanisms of type 1 VWD mutations R1205H and Y1584C through in vitro and in vivo mouse models

Functional characterization of a 13-bp deletion (c.-1522_-1510del13) in the promoter of the von Willebrand factor gene in type 1 von Willebrand disease

In Vitro and In Vivo Mouse Models of the Type 1 Von Willebrand Disease Mutations Y1584C and R1205H.

The mutational spectrum of type 1 von Willebrand disease: results from a Canadian cohort study

Identification and functional characterization of a novel 27-bp deletion in the macroglycopeptide-coding region of the GPIBA gene resulting in platelet-type von Willebrand disease

Cell type–specific regulation of von Willebrand factor expression by the E4BP4 transcriptional repressor

Identification and Functional Characterization of a Novel 27bp Deletion in the Macroglycopeptide-Coding Region of the GPIbα Gene Resulting in Platelet-Type Von Willebrand Disease.

Systemic delivery of an adenoviral vector encoding canine factor VIII results in short-term phenotypic correction, inhibitor development, and biphasic liver toxicity in hemophilia A dogs

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American Society of Hematology

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ASH Publications

American Society of Hematology

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