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Journal Articles

The Ubiquitin Ligase DTX2 Promotes Nuclear Export of RUNX1 and Inhibits RUNX1-Dependent Leukemogenesis

Taishi Yonezawa, MSc, Hirotaka Takahasi, PhD, Tatsuya Sawasaki, PhD, Toshio Kitamura, MD PhD, Susumu Goyama, MD PhD

Blood (2019) 134 (Supplement_1): 1252.

https://doi.org/10.1182/blood-2019-126264

Published: 2019

Journal Articles

The RNA Binding Protein MSI2 Has Increased RNA Binding Activity in Leukemic Stem Cells Compared to Normal Hematopoietic Stem Cells

Diu Nguyen, PhD, Yuheng Lu, PhD, Zi-ning Choo, Christopher Chin, Camila Prieto, BA, Saroj Gourkanti, BA, Christina Leslie, PhD, Michael G. Kharas, PhD

Blood (2018) 132 (Supplement 1): 884.

https://doi.org/10.1182/blood-2018-99-118949

Published: 2018

Journal Articles

Direct Binding of BCOR, but Not CBX8, to MLL-AF9 Is Essential for MLL-AF9 Leukemia Via Regulation of the EYA1/SIX1 Gene Network

John H. Bushweller, PhD, Charles Schmidt, Nicholas Achille, Aravinda Kuntimaddi, Adam Boulton, Benjamin Leach, Shubin Zhang, Nancy J. Zeleznik-Le, PhD

Blood (2018) 132 (Supplement 1): 1316.

https://doi.org/10.1182/blood-2018-99-111388

Published: 2018

Journal Articles

Secreted Mutant Calreticulins As Rogue Cytokines Trigger Thrombopoietin Receptor Activation Specifically in CALR Mutated Cells: Perspectives for MPN Therapy

Blood (2018) 132 (Supplement 1): 4.

https://doi.org/10.1182/blood-2018-99-118348

Published: 2018

Journal Articles

Regulation of Asymmetric Division in Myeloid Leukemogenesis

Jeevisha Bajaj, PhD, Eric L Van Nostrand, PhD, Gene W Yeo, PhD, Tannishtha Reya, PhD

Blood (2017) 130 (Supplement 1): 46.

https://doi.org/10.1182/blood.V130.Suppl_1.46.46

Published: 2017

Journal Articles

O -Fucose and Fringe-Modified Recombinant Notch Peptides As Decoy Molecules to Promote Hematopoietic Progenitor Mobilization

Lan Zhou, MD, Shuiliang Yu, PhD, Weihuan Wang, MD PhD, Marwah Albakri, Seunghwan Lim, Chris Siebel, PhD BA, Hillard M Lazarus, MD, John Letterio, MD, Wei Xin, MD PhD

Blood (2017) 130 (Supplement 1): 1903.

https://doi.org/10.1182/blood.V130.Suppl_1.1903.1903

Published: 2017

Journal Articles

Synthetic Lethal Screening Identifies CHK1 Inhibition As an Exploitable Vulnerability in EZH2 Deficient T-ALL

Theresa E. Leon, PhD MSc, BSc, Tanya Rapoz-D'Silva, BSc, MSc, Sunniyat Rahman, MBiochem, DIC, PhD, Michael Magnussen, BSc, MSc, Nadine Farah, MBBChir, MA, MRCP, FRCPath, Jose A. Guerra-Assunção, BSc, PhD, Rajeev Gupta, MB.ChB, PhD FRCP, FRCPath, Elisabeth P. Nacheva, MD PhD, Javier Herrero, PhD, David C. Linch, FRCP, Marc R. Mansour, MD PhD FRCPath

Blood (2017) 130 (Supplement 1): 1325.

https://doi.org/10.1182/blood.V130.Suppl_1.1325.1325

Published: 2017

Journal Articles

FOXtrotting with PUMILIOs

Arefeh Rouhi, Florian Kuchenbauer

Blood (2017) 129 (18): 2459–2460.

https://doi.org/10.1182/blood-2017-03-771469

Published: 2017

Journal Articles

RUNX1-ETO-Dependent Transcriptional Repression of RASSF2 Contributes to t(8;21) Leukemia through Evasion of MST1-Driven Apoptosis Signaling

Samuel A. Stoner, Elizabeth T. Andrews, Russell Dekelver, PhD, Stephanie Weng, PhD, Miao-Chia Lo, PhD, Kun-Liang Guan, PhD, Dong-Er Zhang, PhD

Blood (2016) 128 (22): 1547.

https://doi.org/10.1182/blood.V128.22.1547.1547

Published: 2016

Journal Articles

HOXB-AS3 Regulates Cell Cycle Progression and Interacts with the Drosophila Splicing Human Behavior (DSHB) Complex in NPM1 -Mutated Acute Myeloid Leukemia

Dimitrios Papaioannou, MD, Andreas Petri, PhD MSc, Charlotte Albæk Thrue, MSc, Stefano Volinia, PhD, Karl Kroll, Yan Pearlly, PhD RD, Ralf Bundschuh, PhD, Guramrit Singh, PhD, Sakari Kauppinen, PhD, Clara D. Bloomfield, MD, Adrienne Dorrance, PhD, Ramiro Garzon, MD

Blood (2016) 128 (22): 1514.

https://doi.org/10.1182/blood.V128.22.1514.1514

Published: 2016

Journal Articles

DLX1 Affects Cell Cycle and Proliferation of Myeloid Leukemia Cells In Vitro and In Vivo

Katerina Rejlova, Miroslava Kardosova, Martina Slamova, Marketa Zaliova, Meritxell Alberich-Jorda, Jan Trka, MD PhD, Julia Starkova

Blood (2016) 128 (22): 1666.

https://doi.org/10.1182/blood.V128.22.1666.1666

Published: 2016

Journal Articles

Coupling Therapeutics to Human Erythrocytes Demonstrates Target-Dependent Effects on Red Cell Physiology While Preserving Efficacy

Carlos Hipolito Villa, MD PhD, Daniel Pan, PhD, Ian Johnston, BS, Colin F Greineder, MD PhD, Marion E. Reid, PhD, Douglas B. Cines, MD, Mortimer Poncz, MD, Don L. Siegel, MD, PhD,, Vladimir R Muzykantov, MD PhD

Blood (2016) 128 (22): 701.

https://doi.org/10.1182/blood.V128.22.701.701

Published: 2016

Journal Articles

PHF19 Promotes Drug Resistance through EZH2 Inactivation in Multiple Myeloma

Tengteng Yu, MD, Lanting Liu, Shuaishuai Zhang, MD, Mu Hao, MD,PhD, Lugui Qiu, MD

Blood (2016) 128 (22): 4495.

https://doi.org/10.1182/blood.V128.22.4495.4495

Published: 2016

Journal Articles

The Direct Notch1 Cofactor Zmiz1 Differentially Regulates Notch1 Signals in a Stage-Specific Manner to Preserve Early T-Cell Precursors and Expand Committed T Cells

Qing Wang, Ran Yan, Nancy Pinnell, Yiran Liu, Amparo Serna Alarcon, Jason Qin, Yitong Chen, Erin Kim, Noah Garber, Ivan Maillard, MD PhD, Tomasz Cierpicki, PhD, Mark Chiang, MD PhD

Blood (2016) 128 (22): 426.

https://doi.org/10.1182/blood.V128.22.426.426

Published: 2016

Journal Articles

The Sea Urchin sns5 Chromatin Insulator Improves the Likelihood of Lentiviral Vectors in Erythroid Milieu By Organizing an Independent Chromatin Domain at the Integration Site

Elena Baiamonte, Rosalia Di Stefano, Melania Lo Iacono, Barbara Spina, Angela Vitrano, Rosario Di Maggio, Massimiliano Sacco, Giovanni Spinelli, Aurelio Maggio, Santina Acuto, Vincenzo Cavalieri

Blood (2015) 126 (23): 4414.

https://doi.org/10.1182/blood.V126.23.4414.4414

Published: 2015

Journal Articles

Analysis of Molecular-Cellular Responses to Proteasome Inhibitors in Multiple Myeloma Patients; A Translational Approach of Proteasome Inhibitors In Vivo Effects from the Drosophila Experimental Model to Humans

Eleni-Dimitra Papanagnou, Tina Bagratuni, Efstathios Kastritis, Issidora Papassideri, Evangelos Terpos, MD, Meletios A. Dimopoulos, Ioannis P. Trougakos

Blood (2015) 126 (23): 3250.

https://doi.org/10.1182/blood.V126.23.3250.3250

Published: 2015

Journal Articles

Bolivian Aymara Natives with Chronic Mountain Sickness Have Autonomous BFU-E Growth

Ricardo Amaru, MD, Ariel Amaru, MD, Hortensia Miguez, Torres Gina, Josue Mamani, Oscar Vera, Heriberto Cuevas, Josef T. Prchal, MD, Jaroslav F Prchal, MD

Blood (2015) 126 (23): 5206.

https://doi.org/10.1182/blood.V126.23.5206.5206

Published: 2015

Journal Articles

Drug Induced MLL Fusion Degradation Via Hsp90 Inhibition

Sandra Cantilena, MPhil, Nicholas Goulden, MD PhD, Owen Williams, PhD, Jasper de Boer, PhD

Blood (2015) 126 (23): 4850.

https://doi.org/10.1182/blood.V126.23.4850.4850

Published: 2015

Journal Articles

Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and D-2-hydroxyglutarate in Drosophila

Zachary J. Reitman, Sergey A. Sinenko, Eric P. Spana, Hai Yan

Blood (2015) 125 (2): 336–345.

https://doi.org/10.1182/blood-2014-05-577940

Published: 2015

Includes: Supplemental data

Journal Articles

Selectively Targeting Mutated NOTCH1 with a Folate-Thapsigargin Derivative

Giovanni Roti, MD, Jun Qi, PhD, Angela Su, B.S., Antony Varca, B.S., Jon C Aster, MD PhD, James E. Bradner, Kimberly Stegmaier, MD

Blood (2014) 124 (21): 2158.

https://doi.org/10.1182/blood.V124.21.2158.2158

Published: 2014

NARROW

The Ubiquitin Ligase DTX2 Promotes Nuclear Export of RUNX1 and Inhibits RUNX1-Dependent Leukemogenesis

The RNA Binding Protein MSI2 Has Increased RNA Binding Activity in Leukemic Stem Cells Compared to Normal Hematopoietic Stem Cells

Direct Binding of BCOR, but Not CBX8, to MLL-AF9 Is Essential for MLL-AF9 Leukemia Via Regulation of the EYA1/SIX1 Gene Network

Secreted Mutant Calreticulins As Rogue Cytokines Trigger Thrombopoietin Receptor Activation Specifically in CALR Mutated Cells: Perspectives for MPN Therapy

Regulation of Asymmetric Division in Myeloid Leukemogenesis

O -Fucose and Fringe-Modified Recombinant Notch Peptides As Decoy Molecules to Promote Hematopoietic Progenitor Mobilization

Synthetic Lethal Screening Identifies CHK1 Inhibition As an Exploitable Vulnerability in EZH2 Deficient T-ALL

FOXtrotting with PUMILIOs

RUNX1-ETO-Dependent Transcriptional Repression of RASSF2 Contributes to t(8;21) Leukemia through Evasion of MST1-Driven Apoptosis Signaling

HOXB-AS3 Regulates Cell Cycle Progression and Interacts with the Drosophila Splicing Human Behavior (DSHB) Complex in NPM1 -Mutated Acute Myeloid Leukemia

DLX1 Affects Cell Cycle and Proliferation of Myeloid Leukemia Cells In Vitro and In Vivo

Coupling Therapeutics to Human Erythrocytes Demonstrates Target-Dependent Effects on Red Cell Physiology While Preserving Efficacy

PHF19 Promotes Drug Resistance through EZH2 Inactivation in Multiple Myeloma

The Direct Notch1 Cofactor Zmiz1 Differentially Regulates Notch1 Signals in a Stage-Specific Manner to Preserve Early T-Cell Precursors and Expand Committed T Cells

The Sea Urchin sns5 Chromatin Insulator Improves the Likelihood of Lentiviral Vectors in Erythroid Milieu By Organizing an Independent Chromatin Domain at the Integration Site

Analysis of Molecular-Cellular Responses to Proteasome Inhibitors in Multiple Myeloma Patients; A Translational Approach of Proteasome Inhibitors In Vivo Effects from the Drosophila Experimental Model to Humans

Bolivian Aymara Natives with Chronic Mountain Sickness Have Autonomous BFU-E Growth

Drug Induced MLL Fusion Degradation Via Hsp90 Inhibition

Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and D-2-hydroxyglutarate in Drosophila

Selectively Targeting Mutated NOTCH1 with a Folate-Thapsigargin Derivative

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American Society of Hematology

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