Page 1 | Search Results | Blood | American Society of Hematology

1-20 of 104

Sort by

Sort Order Select

Journal Articles

Therapeutic inhibition of HIF-2α reverses polycythemia and pulmonary hypertension in murine models of human diseases

Manik C. Ghosh, De-Liang Zhang, Wade H. Ollivierre, Audrey Noguchi, Danielle A. Springer, W. Marston Linehan, Tracey A. Rouault

Blood (2021) 137 (18): 2509–2519.

https://doi.org/10.1182/blood.2020009138

Published: 2021

Includes: Supplemental data

Journal Articles

Phase-I Study of ETA Receptor Antagonist Ambrisentan in Sickle Cell Disease

Abdullah Kutlar, MD, Jennifer Pollock, PhD, Steffen E. Meiler, MD, Ryan Harris, PhD CEP, FACSM, Xu Hongyan, PhD, Leigh Wells, MSN, Latanya Bowman, RN, Sharon Jones, BS, David M. Pollock, PhD

Blood (2019) 134 (Supplement_1): 617.

https://doi.org/10.1182/blood-2019-130036

Published: 2019

Journal Articles

Nicotinamide (NAM) Modulates Transcriptional Signature of Ex Vivo Cultured UCB CD34+ Cells (Omidubicel) and Preserves Their Stemness and Engraftment Potential

Tracey Lodie, PhD, Julian Adams, PhD, Dima Yackoubov, Msc, Yair Steinhardt, MSc, Dorit Ashengrau, Adi Bitansky, Alina Maliutina, Sherry Cohen, Boaz Buhenvald, PhD, Moshe Shahor, PhD, Nathan Dinowitz, PhD, Vered Caspi, PhD, Amnon Peled, PhD, Tony Peled, MSc

Blood (2019) 134 (Supplement_1): 3718.

https://doi.org/10.1182/blood-2019-131124

Published: 2019

Journal Articles

Disease Model of Atherosclerosis Using Werner Syndrome Patient-Derived Induced Pluripotent Stem Cells Reveals Excessive Inflammatory Response Against Ox-LDL

Sudip Kumar Paul, MSc, Masamitsu Sone, PhD, Hisaya Kato, MD PhD, Yoshiro Maezawa, MD PhD, Yasuo Ouchi, PhD, Koutaro Yokote, MD PhD, Koji Eto, MD, Naoya Takayama, MD PhD

Blood (2019) 134 (Supplement_1): 3615.

https://doi.org/10.1182/blood-2019-123919

Published: 2019

Journal Articles

Abnormal Cytokine Production By Mast Cell Cultures from Sickle Cell Anemia Patients in Response to Inflammatory Stimuli and to Co-Culture with Eosinophils

Myriam Salazar-Terreros, PhDMSc, Kleber Yotsumoto Fertrin, MD PhD, Nicolas Moreno Reyes, PhD, Fernando Ferreira Costa, MD PhD, Carla F. Franco-Penteado, BSc, PhD

Blood (2019) 134 (Supplement_1): 3566.

https://doi.org/10.1182/blood-2019-129509

Published: 2019

Journal Articles

Evaluation of Markers of Intravascular Hemolysis and Endothelial Dysfunction in Sickle Cell Anemia Patients with and without Hydroxyurea Therapy

Francine Chenou, Bidossessi Wilfried Hounkpe, Igor de Farias Domingos, MSc, Thais Helena Chaves Batista, Rodrigo Marcionilo Santana, Aderson da Silva Araujo, MD PhD, Marcos Andre Cavalcanti Bezerra, PhD, Fernando Ferreira Costa, MD PhD, Maria de Fátima Sonati, MSc, PhD, Erich V De Paula, MD PhD, Magnun Nueldo Nunes Santos, MSc, PhD

Blood (2019) 134 (Supplement_1): 4826.

https://doi.org/10.1182/blood-2019-131169

Published: 2019

Journal Articles

Imatinib Protects Against Hypoxia/Reoxygenation Induced Lung and Kidney Injury in a Humanized Mouse Model for SCD

Alessandro Mattè, BSc,PhD, Enrica Federti, PhD, Antonio Rechiutti, Amtonella Panataleo, Roberta Russo, Francesco Turrini, MD PhD, Angela Siciliano, Pierre Louis Tharaux, MD PhD, Wassim El Nemer, PhD, Serge Cedrick, Anne Janin, PhD, Christophe Leboeuf, Wilson Babu, Achille Iolascon, MD PhD, Carlo Brugnara, MD, Lucia De Franceschi, MD

Blood (2018) 132 (Supplement 1): 725.

https://doi.org/10.1182/blood-2018-99-115832

Published: 2018

Journal Articles

Heterogeneity in Multi-Organ Expression of HO-1 and PlGF in Sickle Mice Mimic Exposure of Non-Sickle Mice to Extracellular Heme Via Nrf2-Dependent Pathways

Oluwabukola Gbotosho, BSc, MSc, PhD, Maria G Kapetanaki, PhD, Samit Ghosh, PhD, Yu Lin, Frances Weidert, MSc, Solomon Fiifi Ofori-Acquah, PhD, Gregory J. Kato, MD

Blood (2018) 132 (Supplement 1): 2392.

https://doi.org/10.1182/blood-2018-99-113451

Published: 2018

Journal Articles

microRNA and Severity of Sickle Cell Anemia

Thaís Priscila Biassi, MSc, Elvira Maria Guerra-Shinohara, PhD, Patrícia Natália Silva Moretti, PhD, Valeria de Freitas Dutra, MD, Ana Carolina Cabañas-Pedro, MSc, Grazielle Mecabo, PhD, Gisele W. B. Colleoni, PhD, Maria Stella Figueiredo, MD PhD

Blood (2018) 132 (Supplement 1): 3647.

https://doi.org/10.1182/blood-2018-99-115315

Published: 2018

Journal Articles

Next-Generation Sequencing (NGS) in Childhood Myeloproliferative Diseases (MPD)

Michelina Santopietro, MD, Giovanna Palumbo, MD, Maria Luisa Moleti, MD, Anna Maria Testi, MD, Luisa Cardarelli, MD, Nicola Monaco, MDcal Student, Francesco Malaspina, MD, Camilla Presicce, MDcal Student, Sonia Maria Orlando, Alessandro Pancrazzi, PhD, Annalisa Pacilli, PhD, Giada Rotunno, PhD, Alessandro M. Vannucchi, MD, Robin Foà, MD, Fiorina Giona, MD

Blood (2018) 132 (Supplement 1): 3049.

https://doi.org/10.1182/blood-2018-99-118102

Published: 2018

Journal Articles

Excess Mortality in Polycythemia Vera and Essential Thrombocythemia

Arturo Pereira, MD PhD, Carlos Besses Raebel, MD PhD, Juan Carlos Hernandez Boluda, MD PhD, Francisca Ferrer Marin, MD PhD, Carmen Garcia-Hernandez, MD, María Teresa Gómez-Casares, MD PhD, Manuel Pérez-Encinas, MD, María-Soledad Noya, MD, Beatriz Cuevas, MD, Gonzalo Caballero, MD, Maribel Mata, Francisco Cervantes, MD PhD, Alberto Alvarez-Larrán, MD PhD

Blood (2018) 132 (Supplement 1): 3042.

https://doi.org/10.1182/blood-2018-99-109892

Published: 2018

Journal Articles

Heme Regulates the Expression in Erythroblasts of Placenta Growth Factor, a Contributor to Pulmonary Hypertension in Sickle Cell Disease, through the Oxidant Response Transcription Factor NRF2

Maria G Kapetanaki, PhD, Oluwabukola Gbotosho, BSc, MSc, PhD, Deva Sharma, MD MS, Schrott Valerie, MS, Frances Weidert, MSc, Solomon Fiifi Ofori-Acquah, PhD, Grant C. Bullock, MD PhD, Gregory J. Kato, MD

Blood (2017) 130 (Supplement 1): 3496.

https://doi.org/10.1182/blood.V130.Suppl_1.3496.3496

Published: 2017

Journal Articles

Free Heme Induces a Heme Importer, Heme Catabolism and an Angiogenic Factor in Multiple Organs in Mice: Implications for Organ-Specific Response to Intravascular Hemolysis

Oluwabukola Gbotosho, BSc, MSc, PhD, Maria G Kapetanaki, PhD, Yu Lin, Frances Weidert, MSc, Solomon Fiifi Ofori-Acquah, PhD, Gregory J. Kato, MD

Blood (2017) 130 (Supplement 1): 3468.

https://doi.org/10.1182/blood.V130.Suppl_1.3468.3468

Published: 2017

Journal Articles

Vascular and Hemostatic Alterations Associated with Pulmonary Hypertension in β-Thalassemia Hemoglobin E Patients Receiving Regular Transfusion and Iron Chelation

Noppacharn Uaprasert, MB, BCH, Sudarat Satitthummanid, MD MSc, Benjaporn Akkawat, BSc, Pranee Sutcharitchan, MD, Ponlapat Rojnuckarin, MD PhD

Blood (2017) 130 (Supplement 1): 1029.

https://doi.org/10.1182/blood.V130.Suppl_1.1029.1029

Published: 2017

Journal Articles

Correlation of Mutational Profile and Response in Patients with Polycythemia Vera and Essential Thrombocythemia Treated with Pegylated Interferon Alfa 2a As Part of a Prospective Phase II Study

Lucia Masarova, MD, Keyur Patel, MD PhD, Saradhi Mallampathi, PhD, Yawa Dzifa Duose, PhD, Kate J Newberry, PhD, Jorge E. Cortes, MD, Zeev Estrov, MD, Hagop M. Kantarjian, MD, Raja Luthra, Srdan Verstovsek, MD PhD

Blood (2017) 130 (Supplement 1): 1640.

https://doi.org/10.1182/blood.V130.Suppl_1.1640.1640

Published: 2017

Journal Articles

Monocytic Myeloid-Derived Suppressor Cells (Mo-MDSC) Are Increased but Not M1 or M2 TAM Macrophages in the Bone Marrow of Patients with BCR-ABL Negative Myeloid Neoplasm (MPN)

Chi Chen, MD PhD, Andrei Bandarchuk, MD, Ching Wong, MD, Vladimir K. Gotlieb, MD, Hamza Minhas, MBBS, Gardith Joseph, MD, Sophia Tribie, Jen-Chin Wang, MD

Blood (2017) 130 (Supplement 1): 5266.

https://doi.org/10.1182/blood.V130.Suppl_1.5266.5266

Published: 2017

Journal Articles

Nrf2 Activation Attenuates Hemolysis but Promotes Pulmonary Vascular Dysfunction in Sickle Mice

Chibueze A. Ihunnah, PhD, Samit Ghosh, PhD, Scott A. Hahn, MS, Adam C Straub, PhD, Solomon F Ofori-Acquah, PhD

Blood (2016) 128 (22): 1296.

https://doi.org/10.1182/blood.V128.22.1296.1296

Published: 2016

Journal Articles

Activation of the Mineralocorticoid Receptor Stimulates Protein Disulfide Isomerase: Role in Sickle Cell Disease

Alexandra Lozano, Christopher Vega, Yaritza Inostroza-Nieves, Lorena Rivera González, Pablo J. López, Jamie Rosado Alicea, Gregory N. Prado, Alicia Rivera, Jose R. Romero

Blood (2016) 128 (22): 1351.

https://doi.org/10.1182/blood.V128.22.1351.1351

Published: 2016

Journal Articles

A Novel Beneficial Role for Macitentan in Patients at High Thrombosis Risk: Attenuation of Platelet-Mediated Derangements of Blood Coagulation in Eisenmenger Syndrome

Barry Kevane, MB, Seamus Allen, PhD, Kevin Walsh, MD, Karl Egan, PhD, Patricia Maguire, PhD, Damien Kenny, MD, Susan Crawford, BSc, Áine Lennon, BSc, Rhona Savage, BSc, Esther Doran, BSc, Elaine Neary, MD, Fionnuala Ní Áinle, MD PhD

Blood (2016) 128 (22): 2602.

https://doi.org/10.1182/blood.V128.22.2602.2602

Published: 2016

Journal Articles

De Novo DNA Methylation Is Associated with Granulopoiesis and Megakaryopoiesis but Not Erythropoiesis

Jens Lichtenberg, PhD, Elisabeth F. Heuston, PhD, Stacie M. Anderson, NIH Intramural Sequencing Center, Cheryl A. Keller, PhD, Ross C. Hardison, PhD, David M. Bodine, PhD

Blood (2016) 128 (22): 3868.

https://doi.org/10.1182/blood.V128.22.3868.3868

Published: 2016

NARROW

Therapeutic inhibition of HIF-2α reverses polycythemia and pulmonary hypertension in murine models of human diseases

Phase-I Study of ETA Receptor Antagonist Ambrisentan in Sickle Cell Disease

Nicotinamide (NAM) Modulates Transcriptional Signature of Ex Vivo Cultured UCB CD34+ Cells (Omidubicel) and Preserves Their Stemness and Engraftment Potential

Disease Model of Atherosclerosis Using Werner Syndrome Patient-Derived Induced Pluripotent Stem Cells Reveals Excessive Inflammatory Response Against Ox-LDL

Abnormal Cytokine Production By Mast Cell Cultures from Sickle Cell Anemia Patients in Response to Inflammatory Stimuli and to Co-Culture with Eosinophils

Evaluation of Markers of Intravascular Hemolysis and Endothelial Dysfunction in Sickle Cell Anemia Patients with and without Hydroxyurea Therapy

Imatinib Protects Against Hypoxia/Reoxygenation Induced Lung and Kidney Injury in a Humanized Mouse Model for SCD

Heterogeneity in Multi-Organ Expression of HO-1 and PlGF in Sickle Mice Mimic Exposure of Non-Sickle Mice to Extracellular Heme Via Nrf2-Dependent Pathways

microRNA and Severity of Sickle Cell Anemia

Next-Generation Sequencing (NGS) in Childhood Myeloproliferative Diseases (MPD)

Excess Mortality in Polycythemia Vera and Essential Thrombocythemia

Heme Regulates the Expression in Erythroblasts of Placenta Growth Factor, a Contributor to Pulmonary Hypertension in Sickle Cell Disease, through the Oxidant Response Transcription Factor NRF2

Free Heme Induces a Heme Importer, Heme Catabolism and an Angiogenic Factor in Multiple Organs in Mice: Implications for Organ-Specific Response to Intravascular Hemolysis

Vascular and Hemostatic Alterations Associated with Pulmonary Hypertension in β-Thalassemia Hemoglobin E Patients Receiving Regular Transfusion and Iron Chelation

Correlation of Mutational Profile and Response in Patients with Polycythemia Vera and Essential Thrombocythemia Treated with Pegylated Interferon Alfa 2a As Part of a Prospective Phase II Study

Monocytic Myeloid-Derived Suppressor Cells (Mo-MDSC) Are Increased but Not M1 or M2 TAM Macrophages in the Bone Marrow of Patients with BCR-ABL Negative Myeloid Neoplasm (MPN)

Nrf2 Activation Attenuates Hemolysis but Promotes Pulmonary Vascular Dysfunction in Sickle Mice

Activation of the Mineralocorticoid Receptor Stimulates Protein Disulfide Isomerase: Role in Sickle Cell Disease

A Novel Beneficial Role for Macitentan in Patients at High Thrombosis Risk: Attenuation of Platelet-Mediated Derangements of Blood Coagulation in Eisenmenger Syndrome

De Novo DNA Methylation Is Associated with Granulopoiesis and Megakaryopoiesis but Not Erythropoiesis

Email alerts

ASH Publications

American Society of Hematology

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only