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Journal Articles

Mitapivat Treatment Increases β-Thalassemic Erythroblasts Energy Production and Responsiveness to Oxidative Stress

Alessandro Mattè, Angelo D'Alessandro, Mariarita Bertoldi, Richard Huot Pozzetto, Giovanni Bisello, Andrea Mattarei, Alberto Ongaro, Alice Passarini, Angela Siciliano, Roberta Russo, Achille Iolascon, Carlo Brugnara, Lucia De Franceschi

Blood (2023) 142 (Supplement 1): 3850.

https://doi.org/10.1182/blood-2023-185681

Published: 2023

Journal Articles

17R-Resolvin D1 Improves Inflammatory Cardiomyopathy in a Mouse Model of Sickle Cell Disease

Enrica Federti, Domenico Mattoscio, Antonio Recchiuti, Alessandro Mattè, Maria Monti, Flora Cozzolino, Martina Ceci, Manuela Iezzi, Angela Siciliano, Veronica Riccardi, Alice Passarini, Carlo Brugnara, Lucia De Franceschi

Blood (2023) 142 (Supplement 1): 2496.

https://doi.org/10.1182/blood-2023-185603

Published: 2023

Journal Articles

Colchicine Protects Against Cardiomyopathy in Humanized Mouse Model for Sickle Cell Disease

Enrica Federti, Iana Iatcenko, Alessandra Ghigo, Alessandro Mattè, Veronica Riccardi, Immacolata Andolfo, Angela Siciliano, Filippo Mazzi, Manuela Stella, Luigi Robbiano, Valeria Pinto, Achille Iolascon, Gian Luca Forni, Lucia De Franceschi

Blood (2022) 140 (Supplement 1): 2513–2514.

https://doi.org/10.1182/blood-2022-163037

Published: 2022

Journal Articles

Nrf2 Plays a Key Role in Iron-Overload Cardiomyopathy

Enrica Federti, Francesca Vinchi, Iana Iatcenko, Alessandra Ghigo, Alessandro Mattè, Serge Cedrick, Angela Siciliano, Deborah Chiabrando, Emanuela Tolosano, S. Zebulon Vance, Veronica Riccardi, Immacolata Andolfo, Achille Iolascon, Lucia de Franceschi

Blood (2021) 138 (Supplement 1): 3068.

https://doi.org/10.1182/blood-2021-146157

Published: 2021

Journal Articles

Mitapivat Improves Transfusion Burden and Reduces Iron Overload in Thalassemic Mice

Alessandro Mattè, Penelope A. Kosinski, Enrica Federti, Lenny Dang, Angela Siciliano, Iana Iatcenko, Carlo Brugnara, Lucia De Franceschi

Blood (2021) 138 (Supplement 1): 2016.

https://doi.org/10.1182/blood-2021-153721

Published: 2021

Journal Articles

Resolution of sickle cell disease–associated inflammation and tissue damage with 17 R -resolvin D1

Alessandro Matte, Antonio Recchiuti, Enrica Federti, Bérengère Koehl, Thomas Mintz, Wassim El Nemer, Pierre-Louis Tharaux, Valentine Brousse, Immacolata Andolfo, Alessia Lamolinara, Olga Weinberg, Angela Siciliano, Paul C. Norris, Ian R. Riley, Achille Iolascon, Charles N. Serhan, Carlo Brugnara, Lucia De Franceschi

Blood (2019) 133 (3): 252–265.

https://doi.org/10.1182/blood-2018-07-865378

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

Dietary Omega-3 Fatty Acid Supplementation Improves Sickle Cell Bone Disease By Affecting Osteoblastogenesis and Adipogenesis

Maria Teresa Valenti, PhD, Luca Dalle Carbonare, MD, Alessandro Mattè, BSc, PhD, Lorenzo Anez-Bustillos, Mark Puder, MD, Samuele Cheri, Michela Deiana, Enrica Federti, PhD, Serge Cedrick Toya Mbiandjeu, Angela Siciliano, Carlo Brugnara, MD, Lucia De Franceschi, MD

Blood (2018) 132 (Supplement 1): 2356.

https://doi.org/10.1182/blood-2018-99-115801

Published: 2018

Journal Articles

Imatinib Protects Against Hypoxia/Reoxygenation Induced Lung and Kidney Injury in a Humanized Mouse Model for SCD

Alessandro Mattè, BSc,PhD, Enrica Federti, PhD, Antonio Rechiutti, Amtonella Panataleo, Roberta Russo, Francesco Turrini, MD PhD, Angela Siciliano, Pierre Louis Tharaux, MD PhD, Wassim El Nemer, PhD, Serge Cedrick, Anne Janin, PhD, Christophe Leboeuf, Wilson Babu, Achille Iolascon, MD PhD, Carlo Brugnara, MD, Lucia De Franceschi, MD

Blood (2018) 132 (Supplement 1): 725.

https://doi.org/10.1182/blood-2018-99-115832

Published: 2018

Journal Articles

Fyn Kinase Is Involved in EPO Receptor Signaling and Is Required to Harmonize the Response to Oxidation

Elisabetta Beneduce, Alessandro Mattè, PhD, Luigia De Falco, Serge Cedrick, Emanuela Tolosano, Deborah Chiabrando, Angela Siciliano, Achille Iolascon, MD PhD, Mohandas Narla, DSc, Lucia De Franceschi, MD

Blood (2017) 130 (Supplement 1): 9.

https://doi.org/10.1182/blood.V130.Suppl_1.9.9

Published: 2017

Journal Articles

Reprogramming Cell-Signaling By Delivering the Catalytic Domain of Ptpgr Ameliorates Anemia of β-Thalassemia

Alessandro Mattè, PhD, Elisabetta Beneduce, Michela Mirenda, PhD, Roberta Russo, Achille Iolascon, MD PhD, Antonella Pantaleo, PhD, Francesco Turrini, MD PhD, Angela Siciliano, Enrica Federti, PhD, Serge Cedrick, Anne Janin, PhD, Christophe Leboeuf, Carlo Laudanna, MD, Lucia De Franceschi, MD

Blood (2017) 130 (Supplement 1): 2219.

https://doi.org/10.1182/blood.V130.Suppl_1.2219.2219

Published: 2017

Journal Articles

A new molecular link between defective autophagy and erythroid abnormalities in chorea-acanthocytosis

Francesca Lupo, Elena Tibaldi, Alessandro Matte, Alok K. Sharma, Anna Maria Brunati, Seth L. Alper, Carlo Zancanaro, Donatella Benati, Angela Siciliano, Mariarita Bertoldi, Francesca Zonta, Alexander Storch, Ruth H. Walker, Adrian Danek, Benedikt Bader, Andreas Hermann, Lucia De Franceschi

Blood (2016) 128 (25): 2976–2987.

https://doi.org/10.1182/blood-2016-07-727321

Published: 2016

Includes: Supplemental data

Journal Articles

A Selective ORAL GLYT1 Inhibitor, Improves Anemia and RED CELL Survival in a MOUSE MODEL of Beta-Thalassemia

Carlo Brugnara, MD, Anja Harmeier, Lucia De Franceschi, MD, Alessandro Matte, Michael Winter, Annette Koerner, Omar Khwaja, Thomas Singer, Elisabetta Beneduce, Enrica Federti, Angela Siciliano

Blood (2016) 128 (22): 1284.

https://doi.org/10.1182/blood.V128.22.1284.1284

Published: 2016

Journal Articles

Peroxiredoxin-2: A Novel Factor Involved in Iron Homeostasis

Alessandro Mattè, PhD, Luigia De Falco, Enrica Federti, Sonia Levi, PhD, Achille Iolascon, MD PhD, Giorgia Federico, Narla Mohandas, DSc, Anne Janin, MD PhD, Mariasole Bruno, Christophe Leboeuf, PhD, Soo Young Choi, PhD, Dae Won Kim, Francesco Dima, MD, Angela Siciliano, Lucia De Franceschi, MD

Blood (2015) 126 (23): 406.

https://doi.org/10.1182/blood.V126.23.406.406

Published: 2015

Journal Articles

Resolvin D1 and Resolvin D2 Protect Against Hypoxia/Reoxygenation Induced Lung and Kidney Damage in a Sickle Cell Mouse Model of Acute Vaso-Occlusive Crisis

Alessandro Mattè, PhD, Antonio Recchiuti, PhD, Charles Serhan, PhD, Angela Siciliano, Enrica Federti, Olga Weinberg, MD, Brian Kalish, MD, Carlo Brugnara, MD, Lucia De Franceschi, MD

Blood (2015) 126 (23): 966.

https://doi.org/10.1182/blood.V126.23.966.966

Published: 2015

Journal Articles

Hypoxia-reperfusion affects osteogenic lineage and promotes sickle cell bone disease

Luca Dalle Carbonare, Alessandro Matte’, Maria Teresa Valenti, Angela Siciliano, Antonio Mori, Vittorio Schweiger, Gino Zampieri, Luigi Perbellini, Lucia De Franceschi

Blood (2015) 126 (20): 2320–2328.

https://doi.org/10.1182/blood-2015-04-641969

Published: 2015

Includes: Supplemental data

Journal Articles

Dietary ω-3 Fatty Acid Supplementation As a Potential New Therapy for Vasculopathy in Sickle Cell Disease: Proof of Concept in a Transgenic Mouse Model

Brian T Kalish, MD, Alessandro Matte, PhD, Immacolata Andolfo, Achille Iolascon, Olga Weinberg, Angela Siciliano, Mrs, Enrica Federti, Mark Puder, MD PhD, Carlo Brugnara, MD, Lucia De Franceschi, MD

Blood (2014) 124 (21): 220.

https://doi.org/10.1182/blood.V124.21.220.220

Published: 2014

Journal Articles

Zoledronic Acid Reverses Acute Bone Impairment in a Mouse Model for Sickle Cell Disease

Luca Dalle Carbonare, Alessandro Matte, Maria Teresa Valenti, Angela Siciliano, Mrs, Arianna Cristellon, Lucia De Franceschi, MD

Blood (2014) 124 (21): 222.

https://doi.org/10.1182/blood.V124.21.222.222

Published: 2014

Journal Articles

Resveratrol Induces Erythroid Maturation by Activating FOXO3 and Improves in Vivo Erythropoiesis in Normal and Beta -Thalassemic Mice

Sara Santos Franco, PhD student, Luigia De Falco, PhD, Saghi Ghaffari, MD, PhD, Carlo Brugnara, M.D., David Sinclair, PhD, Achille Iolascon, MD, PhD, Mohandas Narla, DSc, Mariarita Bertoldi, PhD, Christophe Lebouf, PhD, Anne Janin, MD, PhD, Angela Siciliano, Mrs, Pauline Rimmele, PhD, Maria Domenica Cappellini, MD, Shady Michan, PhD, Elisa Zoratti, PhD, Lucia De Franceschi, MD

Blood (2012) 120 (21): 3191.

https://doi.org/10.1182/blood.V120.21.3191.3191

Published: 2012

Journal Articles

Pharmacological Inhibition of Calpain-1 Prevents Red Cell Dehydration and Reduces Gardos Channel Activity in a Mouse Model of Sickle Cell Disease. Identification of Druggable Protease Target

Lucia De Franceschi, MD, Alessandro Mattè, PhD, Carlo Brugnara, MD, Angela Siciliano, Mariarita Bertoldi, PhD, Adam Wieschhaus, PhD, Athar H. Chishti, PhD

Blood (2011) 118 (21): 852.

https://doi.org/10.1182/blood.V118.21.852.852

Published: 2011

Journal Articles

Erythrocyte membrane changes of chorea-acanthocytosis are the result of altered Lyn kinase activity

Lucia De Franceschi, Carlo Tomelleri, Alessandro Matte, Anna Maria Brunati, Petra H. Bovee-Geurts, Mariarita Bertoldi, Edwin Lasonder, Elena Tibaldi, Adrian Danek, Ruth H. Walker, Hans H. Jung, Benedikt Bader, Angela Siciliano, Emanuela Ferru, Narla Mohandas, Giel J. C. G. M. Bosman

Blood (2011) 118 (20): 5652–5663.

https://doi.org/10.1182/blood-2011-05-355339

Published: 2011

Includes: Supplemental data

NARROW

Mitapivat Treatment Increases β-Thalassemic Erythroblasts Energy Production and Responsiveness to Oxidative Stress

17R-Resolvin D1 Improves Inflammatory Cardiomyopathy in a Mouse Model of Sickle Cell Disease

Colchicine Protects Against Cardiomyopathy in Humanized Mouse Model for Sickle Cell Disease

Nrf2 Plays a Key Role in Iron-Overload Cardiomyopathy

Mitapivat Improves Transfusion Burden and Reduces Iron Overload in Thalassemic Mice

Resolution of sickle cell disease–associated inflammation and tissue damage with 17 R -resolvin D1

Dietary Omega-3 Fatty Acid Supplementation Improves Sickle Cell Bone Disease By Affecting Osteoblastogenesis and Adipogenesis

Imatinib Protects Against Hypoxia/Reoxygenation Induced Lung and Kidney Injury in a Humanized Mouse Model for SCD

Fyn Kinase Is Involved in EPO Receptor Signaling and Is Required to Harmonize the Response to Oxidation

Reprogramming Cell-Signaling By Delivering the Catalytic Domain of Ptpgr Ameliorates Anemia of β-Thalassemia

A new molecular link between defective autophagy and erythroid abnormalities in chorea-acanthocytosis

A Selective ORAL GLYT1 Inhibitor, Improves Anemia and RED CELL Survival in a MOUSE MODEL of Beta-Thalassemia

Peroxiredoxin-2: A Novel Factor Involved in Iron Homeostasis

Resolvin D1 and Resolvin D2 Protect Against Hypoxia/Reoxygenation Induced Lung and Kidney Damage in a Sickle Cell Mouse Model of Acute Vaso-Occlusive Crisis

Hypoxia-reperfusion affects osteogenic lineage and promotes sickle cell bone disease

Dietary ω-3 Fatty Acid Supplementation As a Potential New Therapy for Vasculopathy in Sickle Cell Disease: Proof of Concept in a Transgenic Mouse Model

Zoledronic Acid Reverses Acute Bone Impairment in a Mouse Model for Sickle Cell Disease

Resveratrol Induces Erythroid Maturation by Activating FOXO3 and Improves in Vivo Erythropoiesis in Normal and Beta -Thalassemic Mice

Pharmacological Inhibition of Calpain-1 Prevents Red Cell Dehydration and Reduces Gardos Channel Activity in a Mouse Model of Sickle Cell Disease. Identification of Druggable Protease Target

Erythrocyte membrane changes of chorea-acanthocytosis are the result of altered Lyn kinase activity

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American Society of Hematology

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