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Journal Articles

Risk Factors of Acute Pancreatitis in Pediatric Acute Lymphoblastic Leukemia Patients: A Single-Center Experience

Soyoon MIN, MD, Hyery Kim, MD, Juhee Shin, Jin Kyung Suh, MD, Sung Han Kang, MD, Kyung-Nam Koh, MD, Ho Joon Im, MD, Jong Jin Seo, MD

Blood (2019) 134 (Supplement_1): 5077.

https://doi.org/10.1182/blood-2019-128236

Published: 2019

Journal Articles

Toxicity of a Modified Peg-Asparaginase-Based SMILE Regimen Is Comparable to L-Asparaginase-Based SMILE in a Non-Asian Population

Ryan J Caddell, PharmD, BCOP, Hayder Saeed, MD, Rebecca Nelson, PharmD, BCOP, Leidy Isenalumhe, MD, Julio Chavez, Celeste Bello, MD, Javier Pinilla Ibarz, MD PhD, Lubomir Sokol, MD PhD, Bijal Shah, MD

Blood (2019) 134 (Supplement_1): 5292.

https://doi.org/10.1182/blood-2019-128435

Published: 2019

Journal Articles

Pediatric-Inspired Chemotherapy Incorporating Pegaspargase Is Safe and Results in High Rates of MRD Negativity in Adults Ages 18-60 with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

Mark Blaine Geyer, MD, Ellen K. Ritchie, MD, Arati V. Rao, MD, M. Isabella Cazacu, Shreya Vemuri, Martin S. Tallman, MD, Dan Douer, MD, Jae H. Park, MD

Blood (2018) 132 (Supplement 1): 4013.

https://doi.org/10.1182/blood-2018-99-115486

Published: 2018

Journal Articles

Monitoring Asparaginase Activity in 21 Patients with Extranodal NK/T-Cell Lymphoma Shows a Very High Proportion of Asparaginase Inactivation

Arnaud Jaccard, MD PhD, Sammara Chaubard, MD, Jean-François Benoist, MD, Lucile Couronne, Laure Philippe, MD, Emmanuel Gyan, MD PhD, Ronan Le Calloch, MD, Aline Moignet Autrel, MD, Rémy Gressin, MD, Jacques Vargaftig, MD PhD, Aline Clavert, MD, Emmanuel Bachy, MD PhD, Olivier Hermine, MD PhD

Blood (2018) 132 (Supplement 1): 5351.

https://doi.org/10.1182/blood-2018-99-118439

Published: 2018

Journal Articles

Chromatin Remodeling Therapy and Capizzi Methotrexate in Treatment-Related MDS/AML

Catherine Aftandilian, MD, Kathleen M. Sakamoto, MD PhD, Kara L. Davis, DO, Gary Van Houten Dahl, MD, Norman J. Lacayo, MD

Blood (2018) 132 (Supplement 1): 5222.

https://doi.org/10.1182/blood-2018-99-110481

Published: 2018

Journal Articles

Erwinia Chrysantemi-Derived L-Asparaginase Strongly Enhances Proteasome Inhibitors Activity By Deregulating Cell Metabolic Programs

Paola Minetto, MD, Debora Soncini, PhD, Fabio Guolo, MD, Samantha Ruberti, BSc, PhD, Veronica Retali, Paola Contini, Nadia Bisso, MD, Nikki Di Felice, MD, Giulia Rivoli, MD, Antonia Cagnetta, MD, Marco Gobbi, MD, Roberto Massimo Lemoli, MD, Michele Cea, MD

Blood (2018) 132 (Supplement 1): 3221.

https://doi.org/10.1182/blood-2018-99-119622

Published: 2018

Journal Articles

Absence of Silent Inactivation Using Intravenous Pegaspargase in Pediatric Acute Lymphoblastic Leukemia

Sarayu Kumar, BA, BSPH, Curtis D Travers, MPH, John Bergsagel, MD, Frank G Keller, MD, Melinda Pauly, MD, Himalee Sabnis, MDMS, Sharon M. Castellino, MD MSc, Glen Lew, MD

Blood (2017) 130 (Supplement 1): 100.

https://doi.org/10.1182/blood.V130.Suppl_1.100.100

Published: 2017

Journal Articles

Use of Premedication Prior to Asparaginase (ASNase) Administration in Pediatric Acute Lymphoblastic Leukemia (ALL): Effect on Treatment Completion Rate

Celine Bernard, MBA, Nathan Rustay, PhD, Kira Mamedov, MD

Blood (2017) 130 (Supplement 1): 5574.

https://doi.org/10.1182/blood.V130.Suppl_1.5574.5574

Published: 2017

Journal Articles

Collaborative Risk-Adapted Treatment for Pediatric Acute Lymphoblastic Leukemia in Mexico

Pablo Gonzalez-Montalvo, MD, Hugo Romo, MD, Lourdes Vega-Vega, MD, Fernando Sanchez-Zubieta, MD, Eduardo Altamirano-Alvarez, MD, Rebeca Rivera-Gomez, MD, Maite Echavarria-Valenzuela, MD, Oscar Gonzalez-Ramella, MD, Daniela Covarrubias-Zapata, MD, Mónica Malavar-Guadarrama, MD, Paula Aristizabal, MD, Paola Friedrich, MD, Gaston K Rivera, MD, Carlos Rodriguez-Galindo, MD

Blood (2017) 130 (Supplement 1): 2116.

https://doi.org/10.1182/blood.V130.Suppl_1.2116.2116

Published: 2017

Journal Articles

Glutamine-Dependence Targeting By Asparaginase Significantly Increases Anti-Myeloma Activity of Proteasome Inhibitors

Paola Minetto, MD, Debora Soncini, PhD, Antonia Cagnetta, MD, Fabio Guolo, MD, Veronica Retali, Giulia Rivoli, MD, Nadia Bisso, MD, Nikki Di Felice, MD, Maurizio Miglino, PhD, Letizia Canepa, MD, Roberto Massimo Lemoli, MD, Marco Gobbi, MD, Michele Cea

Blood (2017) 130 (Supplement 1): 1796.

https://doi.org/10.1182/blood.V130.Suppl_1.1796.1796

Published: 2017

Journal Articles

Randomized Study of Pegasparagase (SS-PEG) and Calaspargase Pegol (SC-PEG) in Pediatric Patients with Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma: Results of DFCI ALL Consortium Protocol 11-001

Blood (2016) 128 (22): 175.

https://doi.org/10.1182/blood.V128.22.175.175

Published: 2016

Journal Articles

A Pediatric-Inspired Regimen Containing Multiple Doses of Intravenous Pegylated Asparaginase Appears Safe and Effective in Newly Diagnosed Adult Patients with Ph-Negative Acute Lymphoblastic Leukemia in Adults up to Age 60: Results of a Multi-Center Phase II Clinical Trial

Jae H. Park, MD, Ellen K. Ritchie, MD, Arati V. Rao, Sean Devlin, PhD, Meier Hsu, MS, Talal T Khawaja, B.S., Bridget A O'Donnell, B.S., Maria I Cazacu, B.S., Diane M Stopka, MS, Martin S. Tallman, MD, Dan Douer, MD

Blood (2016) 128 (22): 1629.

https://doi.org/10.1182/blood.V128.22.1629.1629

Published: 2016

Journal Articles

Population Pharmacokinetic Modeling of Intravenous Asparaginase Erwinia Chrysanthemi : Impact of Varied Infusion Rates on Exposure

Katie Zomorodi, PhD, Todd Dumas, PharmD, Seth Berry, PharmD, Curtis Johnston, PharmD, Mark Eller, PhD

Blood (2016) 128 (22): 1631.

https://doi.org/10.1182/blood.V128.22.1631.1631

Published: 2016

Journal Articles

Anti-Pegaspargase, Anti-Calaspargase Pegol , and Anti-Polyethelene Glycol Antibody Incidence in High Risk Acute Lymphoblastic Leukemia Patients Receiving Pegaspargase or Calaspargase Pegol and Associated Anaphylactic or Hypersensitivity Reaction Rates: Results from Children's Oncology Group (COG) Study AALL07P4

Reuven J Schore, MD, Meenakshi Devidas, PhD, Archie Bleyer, MD, Gregory Reaman, MD, Claudia Lebedinsky, MD, Hui Zhang, MS, Herwig Koppensteiner, PhD, Mignon L. Loh, MD, Elizabeth Raetz, MD, Naomi Winick, MD, William L. Carroll, MD, Stephen P. Hunger, MD, Anne Angiolillo, MD

Blood (2016) 128 (22): 3965.

https://doi.org/10.1182/blood.V128.22.3965.3965

Published: 2016

Journal Articles

Population Pharmacokinetics of Erwinia Asparaginase in Pediatric ALL Patients

Sebastiaan D.T. Sassen, PharmD, Ron A.A. Mathôt, PharmD, PhD, Rob Pieters, MD PhD, Valerie de Haas, MD PhD, Gertjan JL Kaspers, MD PhD, Cor van den Bos, MDPhD, Wim JE Tissing, MD PhD, Maroeska D.W.M. te Loo, MD PhD, Marc B Bierings, MDPhD, Wouter J.W. Kollen, MD PhD, Christian M. Zwaan, MD PhD, Inge M. van der Sluis, MD PhD

Blood (2015) 126 (23): 1281.

https://doi.org/10.1182/blood.V126.23.1281.1281

Published: 2015

Journal Articles

Erwinia Asparaginase Safety and Feasibility during Therapy for Acute Lymphoblastic Leukemia in Adult Patients with Pegaspargase Hypersensitivity or Severe Toxicity

Troy Z Horvat, PharmD, BCOP, Joshua J Pecoraro, PharmD, BCOP, Ryan J Daley, PharmD, BCOP, Larry W Buie, PharmD, BCOP, Dan Douer, MD

Blood (2015) 126 (23): 4915.

https://doi.org/10.1182/blood.V126.23.4915.4915

Published: 2015

Journal Articles

t(12;21)/ ETV6 - RUNX1 Confers a Specific Pattern of In Vivo Sensitivity to Treatments in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL): Results of the Randomized Trials 58881 and 58951 of the EORTC Children Leukemia Group

Blood (2015) 126 (23): 793.

https://doi.org/10.1182/blood.V126.23.793.793

Published: 2015

Journal Articles

Phase I/II Clinical Trial of Erwinia Asparaginase (Erwinase R ) in Combination with Prednisolone, Vincristine and Pirarubicin in Children and Young Adults with Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL)

Chitose Ogawa, MD, Atsushi Manabe, MD PhD, Hiroaki Goto, MD PhD, Katsuyoshi Koh, MD, Daisuke Tomizawa, MD PhD, Keitaro Fukushima, MD PhD, Ken-ichiro Watanabe, MD PhD, Keizo Horibe, MD, Atsushi Kikuta, MD PhD, Mitsuma Hamada, PhD, Akira Ohara, MD PhD

Blood (2014) 124 (21): 3657.

https://doi.org/10.1182/blood.V124.21.3657.3657

Published: 2014

Journal Articles

The Importance of Hypersensitivity in Childhood Acute Lymphoblastic Leukemia

Yesim Oymak, MD, Sultan Aydin Koker, MD, Tuba Hilkay Karapinar, MD, Dilek Ince, MD PhD, Yilmaz Ay, MD, Bengu Demirag, MD, Burcak Tatli Gunes, MD, Esin Albudak Ozcan, MD, Ersin Toret, MD, Neryal Muminoglu, MD, Canan Vergin, MD

Blood (2014) 124 (21): 5242.

https://doi.org/10.1182/blood.V124.21.5242.5242

Published: 2014

Journal Articles

L-Asparaginase Allergic Patients Treated with L-Asparaginase Loaded into Red Blood Cells in an Expanded Access Program. Report of Four Cases

Audrey Contet, MD, Severine Lissandre, MD, Céline Berthon, MD PhD, Yann Godfrin, PhD, Yves Bertrand, MD

Blood (2014) 124 (21): 937.

https://doi.org/10.1182/blood.V124.21.937.937

Published: 2014

NARROW

Risk Factors of Acute Pancreatitis in Pediatric Acute Lymphoblastic Leukemia Patients: A Single-Center Experience

Toxicity of a Modified Peg-Asparaginase-Based SMILE Regimen Is Comparable to L-Asparaginase-Based SMILE in a Non-Asian Population

Pediatric-Inspired Chemotherapy Incorporating Pegaspargase Is Safe and Results in High Rates of MRD Negativity in Adults Ages 18-60 with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

Monitoring Asparaginase Activity in 21 Patients with Extranodal NK/T-Cell Lymphoma Shows a Very High Proportion of Asparaginase Inactivation

Chromatin Remodeling Therapy and Capizzi Methotrexate in Treatment-Related MDS/AML

Erwinia Chrysantemi-Derived L-Asparaginase Strongly Enhances Proteasome Inhibitors Activity By Deregulating Cell Metabolic Programs

Absence of Silent Inactivation Using Intravenous Pegaspargase in Pediatric Acute Lymphoblastic Leukemia

Use of Premedication Prior to Asparaginase (ASNase) Administration in Pediatric Acute Lymphoblastic Leukemia (ALL): Effect on Treatment Completion Rate

Collaborative Risk-Adapted Treatment for Pediatric Acute Lymphoblastic Leukemia in Mexico

Glutamine-Dependence Targeting By Asparaginase Significantly Increases Anti-Myeloma Activity of Proteasome Inhibitors

Randomized Study of Pegasparagase (SS-PEG) and Calaspargase Pegol (SC-PEG) in Pediatric Patients with Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma: Results of DFCI ALL Consortium Protocol 11-001

A Pediatric-Inspired Regimen Containing Multiple Doses of Intravenous Pegylated Asparaginase Appears Safe and Effective in Newly Diagnosed Adult Patients with Ph-Negative Acute Lymphoblastic Leukemia in Adults up to Age 60: Results of a Multi-Center Phase II Clinical Trial

Population Pharmacokinetic Modeling of Intravenous Asparaginase Erwinia Chrysanthemi : Impact of Varied Infusion Rates on Exposure

Population Pharmacokinetics of Erwinia Asparaginase in Pediatric ALL Patients

Erwinia Asparaginase Safety and Feasibility during Therapy for Acute Lymphoblastic Leukemia in Adult Patients with Pegaspargase Hypersensitivity or Severe Toxicity

t(12;21)/ ETV6 - RUNX1 Confers a Specific Pattern of In Vivo Sensitivity to Treatments in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL): Results of the Randomized Trials 58881 and 58951 of the EORTC Children Leukemia Group

Phase I/II Clinical Trial of Erwinia Asparaginase (Erwinase R ) in Combination with Prednisolone, Vincristine and Pirarubicin in Children and Young Adults with Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL)

The Importance of Hypersensitivity in Childhood Acute Lymphoblastic Leukemia

L-Asparaginase Allergic Patients Treated with L-Asparaginase Loaded into Red Blood Cells in an Expanded Access Program. Report of Four Cases

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American Society of Hematology

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American Society of Hematology

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