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Journal Articles

A T-cell–redirecting bispecific G-protein–coupled receptor class 5 member D x CD3 antibody to treat multiple myeloma

Kodandaram Pillarisetti, Suzanne Edavettal, Mark Mendonça, Yingzhe Li, Mark Tornetta, Alexander Babich, Nate Majewski, Matt Husovsky, Dara Reeves, Eileen Walsh, Diana Chin, Leopoldo Luistro, Jocelin Joseph, Gerald Chu, Kathryn Packman, Shoba Shetty, Yusri Elsayed, Ricardo Attar, François Gaudet

Blood (2020) 135 (15): 1232–1243.

https://doi.org/10.1182/blood.2019003342

Published: 2020

Includes: Supplemental data

Journal Articles

Lgr5 Functions As a Critical Negative Regulator of Wnt/β-Catenin Signaling and Is Essential for B-Lymphopoiesis and Malignant B-Cell Transformation

Kadriye Nehir Cosgun, PhD, Gauri Deb, MS, PhD, Xin Yang, MD, Gang Xiao, PhD, Teresa Sadras, PhD, Jaewoong Lee, PhD, Lai N Chan, PhD, Kohei Kume, PhD, Lu Yang, PhD, Huimin Geng, PhD, John Chan, MD, Joo Y. Song, MD, Hassan Jumaa, PhD, Andrew G. Polson, PhD, Hans Clevers, MD PhD, Markus Müschen, MD PhD

Blood (2019) 134 (Supplement_1): 748.

https://doi.org/10.1182/blood-2019-127263

Published: 2019

Journal Articles

Hematopoietic Stem and Progenitor Cells Manifest Direct Migration Towards Secreted DEK in a CXCR2- and G Protein Signaling-Dependent Manner

Maegan L. Capitano, PhD, Yasser Sammour, Maureen Legendre, Scott Cooper, MS, David Markovitz, MD, Hal E. Broxmeyer, PhD

Blood (2019) 134 (Supplement_1): 1196.

https://doi.org/10.1182/blood-2019-128738

Published: 2019

Journal Articles

Blockade of Lipid Receptor GPR31 Suppresses Platelet Reactivity and Thrombosis with Minimal Effect on Hemostasis

Layla Van Doren, MD, Nga Nguyen, BSc, Chris Garzia, BSc, Elizabeth Fletcher, PhD, Ryan Stevenson, MD, David Jaramillo, MSc, Athan Kuliopulos, MD PhD, Lidija Covic, PhD

Blood (2019) 134 (Supplement_1): 1064.

https://doi.org/10.1182/blood-2019-126111

Published: 2019

Journal Articles

The Role of Gα 13 in Integrin β 2 -Dependent Neutrophil Transendothelial Migration

Claire W Chang, BS, Ni Cheng, PhD, Xiaoping Du, MD PhD

Blood (2019) 134 (Supplement_1): 1037.

https://doi.org/10.1182/blood-2019-130526

Published: 2019

Journal Articles

The GPR68/BCL2 Axis Remodels Metabolism in AML By Relocating Calcium

Xiaofei He, B.S., Caleb Hawkins, B.S., Lauren Lawley, B.S., Mark Wunderlich, MS, Benjamin Mizukawa, Xiang-ming Zha, PhD, Stephanie Halene, MD, Jing Fang, MD PhD

Blood (2019) 134 (Supplement_1): 2661.

https://doi.org/10.1182/blood-2019-125455

Published: 2019

Journal Articles

Genome-Wide microRNA Expression Profiling in Molecular Subgroups of Peripheral T-Cell Lymphoma Identified Role of Mir-126 in T-Cell Lymphomagenesis

Waseem Lone, PhD, Alyssa Bouska, PhD, Tyler Herek, BS,MS, Catalina Amador, MD, Mallick Saumyaranajn, MD, Yu Jiayu, Tayla Heavican, Stefano A. Pileri, MD PhD, Timothy McKeithan, MD PhD, Wing C. Chan, MD, Javeed Iqbal, PhD

Blood (2019) 134 (Supplement_1): 2767.

https://doi.org/10.1182/blood-2019-129327

Published: 2019

Journal Articles

GRK6 Regulates the Hemostatic Response to Injury through Its Rate-Limiting Effects on GPCR Signaling in Platelets

Xi Chen, PhD, Shuchi Gupta, Matthew Cooper, Daniel Dehelian, Xuefei Zhao, Lawrence F. Brass, MD PhD, Ulhas P. Naik, PhD, Meghna Ulhas Naik, MS, Jeffrey Benovic, Peisong Ma, PhD

Blood (2019) 134 (Supplement_1): 3611.

https://doi.org/10.1182/blood-2019-129175

Published: 2019

Journal Articles

Identifying miRNA Biomarkers and Predicted Targets Associated with Venous Thromboembolism in Colorectal Cancer Patients

Ann S. Kim, BA, Matthew F Kalady, MD, Jennifer DeVecchio, Kahraman Tanriverdi, Jane E. Freedman, MD, John Barnard, PhD, Tae Hyun Hwang, PhD, Alok A Khorana, MD, Keith R McCrae, MD

Blood (2019) 134 (Supplement_1): 3643.

https://doi.org/10.1182/blood-2019-127585

Published: 2019

Journal Articles

Regulation of Platelet Function By Adenosine Receptors

Daniel N. Darlington, PhD, Xiaowu Wu, MD MSc, Kevin L. Chang, BS, James Bynum, PhD, Andrew P. Cap, MD PhD

Blood (2019) 134 (Supplement_1): 2348.

https://doi.org/10.1182/blood-2019-131129

Published: 2019

Journal Articles

Loss of Gpr68 Enhances Hematopoietic Stem Cell Function during Aging

Xiaofei He, B.S., Caleb Hawkins, B.S., Lauren Lawley, B.S., Yan Xu, PhD, Xiang-ming Zha, PhD, Jing Fang, MD PhD

Blood (2019) 134 (Supplement_1): 3719.

https://doi.org/10.1182/blood-2019-125168

Published: 2019

Journal Articles

Palmitoylation of GNA13 Is Essential for Its Tumor Suppressor Function and Its Inhibition Confers Hypersensitivity of B-Cell Lymphoma to BCL2 Inhibitors

Zhizhou Xia, Xiuli Zhang, Ping Liu, MD PhD, Bo Jiao, PhD, Ruibao Ren, MD PhD

Blood (2019) 134 (Supplement_1): 3787.

https://doi.org/10.1182/blood-2019-126368

Published: 2019

Journal Articles

Novel Role of Raft-Associated Smoothened (SMO) in AKT Signal Regulation in Diffuse Large B Cell Lymphoma

Nitin Agarwal, PhD, Kranthi Kunkalla, Daniel Bilbao, PhD, Ralf Landgraf, PhD, Francisco Vega, MD PhD

Blood (2019) 134 (Supplement_1): 3972.

https://doi.org/10.1182/blood-2019-121847

Published: 2019

Journal Articles

Untangling the Transcriptional Mis-Regulation Driven By Pml;rara

William Villiers, MSc, Paul Lavender, PhD, Audrey Kelly, PhD, Michael Lim, MD PhD, Cameron Osborne, PhD, Richard Dillon, MA, PhD MRCP, FRCPath

Blood (2019) 134 (Supplement_1): 282.

https://doi.org/10.1182/blood-2019-125555

Published: 2019

Journal Articles

Optimal Dual-Targeted CAR Construct Simultaneously Targeting Bcma and GPRC5D Prevents Bcma-Escape Driven Relapse in Multiple Myeloma

Carlos Fernandez de Larrea, MD PhD, Mette Staehr, PhD, Andrea Lopez, Yunxin Chen, MBBS, Terence J Purdon, MS, Khong Y. Ng, PhD, Hans Wendel, MD, Renier J. Brentjens, MD PhD, Eric L Smith, MD PhD

Blood (2019) 134 (Supplement_1): 136.

https://doi.org/10.1182/blood-2019-126145

Published: 2019

Journal Articles

Sphingosine-1-Phosphate Receptor 3 (S1PR3) Promotes Myeloid Commitment of Human Hematopoietic and Leukemic Stem Cells

Stephanie Zhi-Juan Xie, PhD, Kerstin Kaufmann, PhD, Olga I. Gan, PhD, Elisa Laurenti, PhD, Stanley W.K. Ng, Qiang Liu, Melissa Kleinau, Joseph Jargostf, Gareth Holmes, Chiara Luberto, PhD, Lina M Obeid, MD, Yusuf A. Hannun, MD, Jean C.Y. Wang, MD PhD, Mark D. Minden, MD PhD, John E. Dick, PhD

Blood (2018) 132 (Supplement 1): 1329.

https://doi.org/10.1182/blood-2018-99-119128

Published: 2018

Journal Articles

A Heterozygous Mutation of G-Protein-Coupled Receptor 25 in a Family with Inherited Thrombocytopenia and Thrombosis

Jun Yamanouchi, MD PhD, Yuichi Ikeda, MD, Takaaki Hato, MD PhD, Masaki Yasukawa, MD PhD, Katsuto Takenaka, MD PhD

Blood (2018) 132 (Supplement 1): 1151.

https://doi.org/10.1182/blood-2018-99-110275

Published: 2018

Journal Articles

Inflammation and Tissue Damage Mediated By PAR-1 Expression Is Cell Type-Specific and Varies Depending on the Inflammatory Challenge

Alexander A Boucher, MD, Leah A. Rosenfeldt, BS, Duaa Mureb, BS, Anna K Kopec, PhD, James P. Luyendyk, PhD, Matthew J. Flick, PhD, Joseph S. Palumbo, MD

Blood (2018) 132 (Supplement 1): 133.

https://doi.org/10.1182/blood-2018-99-117312

Published: 2018

Journal Articles

CAR T Cell Therapy Targeting G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D), a Novel Target for the Immunotherapy of Multiple Myeloma

Blood (2018) 132 (Supplement 1): 589.

https://doi.org/10.1182/blood-2018-99-110471

Published: 2018

Journal Articles

Mature Osteoblasts Provide a Protective Niche Against Multiple Myeloma Growth and Survival within the Tumor Microenvironment

Keertik Fulzele, PhD, Cristina Panaroni, PhD, Rosemary Soucy, Ka Tat Siu, PhD, Kenta Mukaihara, MD PhD, Noopur Raje, MD

Blood (2018) 132 (Supplement 1): 4476.

https://doi.org/10.1182/blood-2018-99-118377

Published: 2018

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A T-cell–redirecting bispecific G-protein–coupled receptor class 5 member D x CD3 antibody to treat multiple myeloma

Lgr5 Functions As a Critical Negative Regulator of Wnt/β-Catenin Signaling and Is Essential for B-Lymphopoiesis and Malignant B-Cell Transformation

Hematopoietic Stem and Progenitor Cells Manifest Direct Migration Towards Secreted DEK in a CXCR2- and G Protein Signaling-Dependent Manner

Blockade of Lipid Receptor GPR31 Suppresses Platelet Reactivity and Thrombosis with Minimal Effect on Hemostasis

The Role of Gα 13 in Integrin β 2 -Dependent Neutrophil Transendothelial Migration

The GPR68/BCL2 Axis Remodels Metabolism in AML By Relocating Calcium

Genome-Wide microRNA Expression Profiling in Molecular Subgroups of Peripheral T-Cell Lymphoma Identified Role of Mir-126 in T-Cell Lymphomagenesis

GRK6 Regulates the Hemostatic Response to Injury through Its Rate-Limiting Effects on GPCR Signaling in Platelets

Identifying miRNA Biomarkers and Predicted Targets Associated with Venous Thromboembolism in Colorectal Cancer Patients

Regulation of Platelet Function By Adenosine Receptors

Loss of Gpr68 Enhances Hematopoietic Stem Cell Function during Aging

Palmitoylation of GNA13 Is Essential for Its Tumor Suppressor Function and Its Inhibition Confers Hypersensitivity of B-Cell Lymphoma to BCL2 Inhibitors

Novel Role of Raft-Associated Smoothened (SMO) in AKT Signal Regulation in Diffuse Large B Cell Lymphoma

Untangling the Transcriptional Mis-Regulation Driven By Pml;rara

Optimal Dual-Targeted CAR Construct Simultaneously Targeting Bcma and GPRC5D Prevents Bcma-Escape Driven Relapse in Multiple Myeloma

Sphingosine-1-Phosphate Receptor 3 (S1PR3) Promotes Myeloid Commitment of Human Hematopoietic and Leukemic Stem Cells

A Heterozygous Mutation of G-Protein-Coupled Receptor 25 in a Family with Inherited Thrombocytopenia and Thrombosis

Inflammation and Tissue Damage Mediated By PAR-1 Expression Is Cell Type-Specific and Varies Depending on the Inflammatory Challenge

CAR T Cell Therapy Targeting G Protein-Coupled Receptor Class C Group 5 Member D (GPRC5D), a Novel Target for the Immunotherapy of Multiple Myeloma

Mature Osteoblasts Provide a Protective Niche Against Multiple Myeloma Growth and Survival within the Tumor Microenvironment

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