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Journal Articles

A Unique Monocyte Transcriptome Discriminates Sickle Cell Disease from Other Hereditary Hemolytic Anemias and Shows the Particular Importance of Lipid and Interferon Signaling

Annelies J. Van Vuren, MD, Stephanie van Straaten, MD PhD, Michal Mokry, PhD, Richard van Wijk, PhD, Eduard J. van Beers, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 980.
https://doi.org/10.1182/blood-2019-124070
Published: 2019
Journal Articles

Molecular Analysis in Patients with Idiopathic Erythrocytosis

Katarzyna Aleksandra Jalowiec, Naomi A. Porret, PhD, Raphael Joncourt, Alicia Rovo
Journal: Blood
Blood (2019) 134 (Supplement_1): 2230.
https://doi.org/10.1182/blood-2019-128169
Published: 2019
Journal Articles

CRISPR/dCas9 (D10A) -Mediated Hb CS Gene Editing and Identification of Genetically Modified Fibroblasts

Lian Yu, Wei Hao Wu, WANG Shunqing, Ken H. Young, Funeng Jiang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5754.
https://doi.org/10.1182/blood-2019-129931
Published: 2019
Journal Articles

Effects of Voxelotor (GBT440) Therapy on Laboratory Testing of Sickle Cell Patients

Michelle E. Savedra, MT(ASCP), Jessica L. Szuberski, MLS ASCP, Tavanna R. Porter, MS, LCGC, Molly S. Hein, Phuong L. Nguyen, MD, Min Shi, MD PhD, Aruna Rangan, MD, James D. Hoyer, MD, Jennifer L. Oliveira, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1011.
https://doi.org/10.1182/blood-2019-131125
Published: 2019
Journal Articles

Combination of Nilotinib and Pegylated Interferon Alfa-2B Results in High Rates of MR4.5 at 24 Months - Primary Analysis of the ALLG CML 11 Pinnacle Study

David T Yeung, PhDBSc,FRACP,FRCPA,MBBS, Naranie Shanmuganathan, MBBS FRACP FRCPA, Andrew Grigg, Ilona Cunningham, MBBS FRACP FRCPA, Jake Shortt, FRACP,FRCPA,PhD, Philip Rowling, MBBS FRACP FRCPA, John Reynolds, PhD, Rosemary Anne Harrup, MBBS, FRACP, FRCPA, David M Ross, MD PhD, David Kipp, MBBS,FRCPA,FRACP, Anthony K Mills, FRACP, FRCPA, MBBS, Christopher K Arthur, MBBS FRACP FRCPA, Anthony P Schwarer, MD MBBS (Hons), FRACP, FRCPA, Kathryn Jackson, MBBS FRACP FRCPA, Nicholas Viiala, MBBS FRACP FRCPA, Robert Weinkove, MD, Agnes S. M. Yong, MD PhD, Deborah L. White, PhD FFSc (RCPA), Susan Branford, PhD, Timothy P. Hughes, MDMBBS,FRACP,FRCPA, On Behalf of the ALLG
Journal: Blood
Blood (2019) 134 (Supplement_1): 2926.
https://doi.org/10.1182/blood-2019-125740
Published: 2019
Journal Articles

High-Throughput RNA Sequencing Analysis Reveals Distinct Molecular Signature in NRAS and PTPN11 JMML Patients

Pier Paolo Leoncini, PhD, Alessandro Domenico Silvestris, PhD, Patrizia Vitullo, PhD, Marco Zecca, MD, Christian Flotho, MD PhD, Charlotte M. Niemeyer, MD, Angela Gallo, PhD, Alice Bertaina, MD PhD, Franco Locatelli, MD PhD, Pietro Merli, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4229.
https://doi.org/10.1182/blood-2019-129965
Published: 2019
Journal Articles

Validity of HbA1c in Diagnosing Diabetes Among People with Sickle Cell Trait in Tanzania

Belinda Kweka, MD, Eric Lyimo, BSc, Jeremiah Kidola, PhD, Suzanne Filteau, PhD, Henrik Friis, PhD, Alphaxard Manjurano, Daniel Faurholt Jepsen, PhD, George PrayGod, MD, Heimburger Douglas C, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4852.
https://doi.org/10.1182/blood-2019-125326
Published: 2019
Journal Articles

Prevalence and Monitoring of Diabetes Among Adults with Sickle Cell Disease: A Single Institution Experience

Ashley McLean, MS2, Laura Young, MD PhD, Marcella H. Boynton, PhD, Samuel Wilson, MD, Jane A. Little, MD, Marcus A. Carden, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4832.
https://doi.org/10.1182/blood-2019-128843
Published: 2019
Journal Articles

Next-Generation Sequencing (NGS) in Childhood Myeloproliferative Diseases (MPD)

Michelina Santopietro, MD, Giovanna Palumbo, MD, Maria Luisa Moleti, MD, Anna Maria Testi, MD, Luisa Cardarelli, MD, Nicola Monaco, MDcal Student, Francesco Malaspina, MD, Camilla Presicce, MDcal Student, Sonia Maria Orlando, Alessandro Pancrazzi, PhD, Annalisa Pacilli, PhD, Giada Rotunno, PhD, Alessandro M. Vannucchi, MD, Robin Foà, MD, Fiorina Giona, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3049.
https://doi.org/10.1182/blood-2018-99-118102
Published: 2018
Journal Articles

The Association between Circulating Inflammatory Markers and Metabolic Syndrome: A General Population Study

Kasper Mønsted Pedersen, MD, Sabrina Cordua, MD, Hans Carl Hasselbalch, Professor, dr.MD, Christina Ellervik, Associate Professor, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4305.
https://doi.org/10.1182/blood-2018-99-120356
Published: 2018
Journal Articles

Glycemic Control in Patients Treated with Tyrosine Kinase Inhibitors for Chronic Myeloid Leukemia: A Systematic Review

Laura Spatafora, Breanne Golemiec, Lehana Thabane, PhD, Laura Banfield, Christopher M. Hillis, MD, Constantine Samaan, MD, Uma Athale, MD MBBS,MSc
Journal: Blood
Blood (2018) 132 (Supplement 1): 4273.
https://doi.org/10.1182/blood-2018-99-117464
Published: 2018
Journal Articles

Precision Medicine for Sickle Cell Disease through Whole Genome Sequencing

Evadnie Rampersaud, PhD, Lance E. Palmer, PhD, Jane S. Hankins, MD MS, Vivien A Sheehan, MD PhD, Wenjian Bi, PhD, Heather Mulder, BS, Guolian Kang, PhD, Jeremie H. Estepp, MD, Shuoguo Wang, PhD, Andrew Thrasher, PhD, Martha Villavicencio, PhD, Jason R Hodges, PhD MA, Wenan Chen, PhD, Ti-Cheng Chang, PhD, Yong Cheng, PhD, Michael Rusch, BS, Yadav Sapkota, PhD, Akshay Sharma, MBBS, Pavel Sumazin, PhD, Xing Tang, PhD, Amanda M. Brandow, DO, MS, Shawn Levy, Nidal Boulos, PhD, Celeste Rosencrance, BS, Donald Yergeau, PhD, Jeffrey Lebensburger, DO, MSPH, Winfred Wang, MD, Yutaka Yasui, PhD, John Easton, PhD, Michael R. DeBaun, MD, James R. Downing, MD, Jinghui Zhang, Gang Wu, PhD, Mitchell J. Weiss, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3641.
https://doi.org/10.1182/blood-2018-99-117606
Published: 2018
Journal Articles

First Report of α-Thalassemia Genotypes from Transcaucasia

Gunay Aliyeva, Chingiz Asadov, Tahira Mammadova, Zaur Mammadbayov, Eldar Abdulalimov, Surmaya Gafarova
Journal: Blood
Blood (2018) 132 (Supplement 1): 4899.
https://doi.org/10.1182/blood-2018-99-110285
Published: 2018
Journal Articles

Combination of Nilotinib and Pegylated Interferon Alfa-2b Results in High Molecular Response Rates in Chronic Phase CML: Interim Results of the ALLG CML 11 Pinnacle Study

David T Yeung, PhDBSc,FRACP,FRCPA,MBBS, Andrew P. Grigg, MBBS, FRACP, FRCPA, MD, Naranie Shanmuganathan, MBBS, Ilona Cunningham, MBBS FRACP FRCPA, Jake Shortt, FRACP,FRCPA,PhD, Philip Rowling, MBBS FRACP FRCPA, John Reynolds, PhD, Rachel Cushion, Rosemary Anne Harrup, MD, David M Ross, David Kipp, MBBS,FRCPA,FRACP, Anthony K Mills, FRACP, FRCPA, MBBS, Christopher K Arthur, Anthony P Schwarer, MD MBBS(Hons), FRACP, FRCPA, Kathryn Jackson, MBBS FRACP, FRCPA, Nicholas Viiala, MBBS, FRACP, FRCPA, Robert Weinkove, MA, MBBS, PhD, FRCPath, FRACP, Agnes S. M. Yong, MD, PhD, Deborah L White, PhD, Susan Branford, PhD, Timothy P. Hughes, MD, MBBS, FRACP, FRCPA, On Behalf of the ALLG
Journal: Blood
Blood (2018) 132 (Supplement 1): 459.
https://doi.org/10.1182/blood-2018-99-110569
Published: 2018
Journal Articles

GATA/Heme Multi-Omics Reveals a Trace Metal-Dependent Erythrocyte Developmental Mechanism

Nobuyuki Tanimura, PhD, Ruiqi Liao, PhD, Gary M Wilson, Matthew R Dent, Miao Cao, Judith N Burstyn, PhD, Peiman Hematti, MD, Xin Liu, PhD, Yuannyu Zhang, PhD, Ye Zheng, Sunduz Keles, PhD, Jian Xu, PhD, Joshua J Coon, PhD, Emery H Bresnick, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 500.
https://doi.org/10.1182/blood-2018-99-115324
Published: 2018
Journal Articles

Insights into Hematopoiesis in GATA2 Deficiency Using Single-Cell Transcriptomics

Elina A.M. Hirvonen, MSc, Inari Natri, MB, Mattila Pirkko, PhD, Jenni Lahtela, PhD, Pitkänen Esa, PhD, Ulla Wartiovaara-Kautto, MD PhD, Outi Kilpivaara, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2478.
https://doi.org/10.1182/blood.V130.Suppl_1.2478.2478
Published: 2017
Journal Articles

Single Cell Transcriptome Analysis Reveals Changing Levels and Distributions of Stemness across Disease States in Pediatric AML

Lisa Wei, BS, Diane Trinh, Soheil Meshinchi, MD PhD, Marco A. Marra, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3953.
https://doi.org/10.1182/blood.V130.Suppl_1.3953.3953
Published: 2017
Journal Articles

Ameliorating Effects of Very High Hemoglobin F Levels and Glucose-6-Phosphate Dehydrogenase Deficiency in Sickle Cell Patients Along with Associated Clinical Manifestations: A Report from Al Ahsa, Easter Province, Saudi Arabia

Nawaf Alanazi, Alhussain, J . Almulhim, S . AlJaman, M . AlAmer, L . BuAmer , W. Almutlaq, M, AbudalloHull Rula, Giuseppe Saglio, MD PhD, Zafar Iqbal, MPhil PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4803.
https://doi.org/10.1182/blood.V130.Suppl_1.4803.4803
Published: 2017
Journal Articles

Nilotinib in Combination with Pegylated Interferon Alfa-2b for CP-CML Leads to High Molecular Response Rates: Interim Results of the Pinnacle Study

David Yeung, PhDBSc,FRACP,FRCPA,MBBS, Andrew Grigg, MBBS FRACP FRCPA, Naranie Shanmuganathan, MBBS, Ilona Cunningham, MBBS FRACP FRCPA, Jake Shortt, MBBS PhDFRACP FRCPA, Philip Rowling, MBBS FRACP FRCPA, John Reynolds, PhD, Rachel Cushion, Rosemary Harrap, MBBS FRACP FRCPA, David M Ross, MBBS, PhD FRACP, FRCPA, David Kipp, MBBS,FRCPA,FRACP, Anthony K Mills, FRACP, FRCPA, MBBS, Christopher K Arthur, MDFRACP,FRCPA,MBBS, Anthony P Schwarer, MD MBBS (Hons), FRACP, FRCPA, Kathryn Jackson, MBBS FRACP FRCPA, Nicholas Viiala, MBBS FRACP FRCPA, Robert Weinkove, MA, MBBS, PhD FRCPath, FRACP, Agnes S. M. Yong, MDPhD, Deborah L White, PhD FFSc (RCPA), Susan Branford, PhD, Timothy P. Hughes, MD MBBS, FRACP, FRCPA
Journal: Blood
Blood (2017) 130 (Supplement 1): 2898.
https://doi.org/10.1182/blood.V130.Suppl_1.2898.2898
Published: 2017
Journal Articles

Genome Editing Strategies to Treat Beta-Hemoglobinopathies

Mitchell J Weiss, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): SCI-16.
https://doi.org/10.1182/blood.V130.Suppl_1.SCI-16.SCI-16
Published: 2017