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Journal Articles

Therapeutic Targeting of RUNX-NFATC2 Axis for Acute Promyelocytic Leukemia and T Cell Immunity

Hirohito Kubota, MD, Kana Furuichi, Tatsuya Masuda, Toshiya Tatsuta, Hidefumi Hiramatsu, MD PhD, Junko Takita, MD PhD, Sugiyama Hiroshi, PhD, Souichi Adachi, MD PhD, Yasuhiko Kamikubo, MD, PhD

Blood (2019) 134 (Supplement_1): 3359.

https://doi.org/10.1182/blood-2019-126428

Published: 2019

Journal Articles

A Standardized Kit for a Chromogenic Modified Nijmegen-Bethesda Assay: Repeatability, Reproducibility, and Analytical Sensitivity

Colin Douglas, PhD, Tara Quinton, MSc, Ellinore Cabanban, BSc, Karen Black, PhD, Ali Sadeghi-Khomami, PhD

Blood (2018) 132 (Supplement 1): 1201.

https://doi.org/10.1182/blood-2018-99-119491

Published: 2018

Journal Articles

Synthetic Lethal Interaction between Apto-253 and Impaired BRCA1/2 Function

Cheng-Yu Tsai, PhD, Si Sun, MD, Hongying Zhang, MD, Andrea Local, PhD, Khalid Benbatoul, BS, Peter Folger, BS, Susan Sheng, PhD, William Rice, PhD, Stephen Howell, MD

Blood (2017) 130 (Supplement 1): 5000.

https://doi.org/10.1182/blood.V130.Suppl_1.5000.5000

Published: 2017

Journal Articles

Difference in Fibrin Clot Structure in Haemophilia A and Haemophilia B

Vincent Luong, MDcal Student, Nida Soutari, Maria Berndtsson, PhD, Margareta Holmström, MD, Jovan P. Antovic, MD PhD, Roza Chaireti, MD PhD

Blood (2016) 128 (22): 563.

https://doi.org/10.1182/blood.V128.22.563.563

Published: 2016

Journal Articles

Mechanisms of Resistance to Apto-253

Cheng-Yu Tsai, PhD, Hongying Zhang, MD PhD, Andrea Local, PhD, William G. Rice, PhD, Stephen B Howell, MD

Blood (2016) 128 (22): 5247.

https://doi.org/10.1182/blood.V128.22.5247.5247

Published: 2016

Journal Articles

Analysis of Protease Activated Receptor 4 (PAR4) By Histidine Hydrogen Deuterium Exchange

Marvin T. Nieman, PhD, Maria de la Fuente, Masaru Miyagi, PhD

Blood (2014) 124 (21): 4166.

https://doi.org/10.1182/blood.V124.21.4166.4166

Published: 2014

Journal Articles

Clinical and Preclinical Characterisation Of The Metabolites Of The BCR-ABL Tyrosine Kinase Inhibitor Nilotinib

Paul W. Manley, Ph. D., Jürgen Mestan, Ph D, Jennifer Sheng, Ph D, Phi Tran, M Sc, Mark Kagan, Ph D

Blood (2013) 122 (21): 4011.

https://doi.org/10.1182/blood.V122.21.4011.4011

Published: 2013

Journal Articles

Effective Targeting Of The P53/MDM2 Axis In Preclinical Models Of Infant MLL-Rearranged Acute Lymphoblastic Leukemia

Richard B Lock, PhD, Jennifer Richmond, BSc (Hons), Laura High, PhD, Hernan Carol, PhD, Kathryn Evans, BSc (Hons), Agnes M. Mendomo, MSc, Raushan T. Kurmasheva, PhD, Peter J. Houghton, PhD, Malcolm A. Smith, MD, PhD

Blood (2013) 122 (21): 71.

https://doi.org/10.1182/blood.V122.21.71.71

Published: 2013

Journal Articles

Crystal Structure Of Tissue Factor Pathway Inhibitor (TFPI) Kunitz Domain 1 and 2 In Complex With An Inhibitory Cyclic Peptide,

Michael Dockal, PhD, Rudolf Hartmann, PhD, Markus Fries, PhD, Katerina Prohaska, Robert Pachlinger, PhD, Thomas Polakowski, PhD, Johannes Brandstetter, PhD, Jan Rosing, PhD, Friedrich Scheiflinger, PhD

Blood (2013) 122 (21): 453.

https://doi.org/10.1182/blood.V122.21.453.453

Published: 2013

Journal Articles

The Major Phagocyte Peroxidase-Derived Oxidant HOSCN Stimulates Gene-Specific p38 MAPK- Dependent, NF-κb-Mediated Activation of Tissue Factor, VCAM-1 and ICAM-1 Expression In Endothelium.

Teena Rehani, Ph.D., Adria Jonas, M.S., Arne Slungaard, MD

Blood (2010) 116 (21): 1481.

https://doi.org/10.1182/blood.V116.21.1481.1481

Published: 2010

Journal Articles

The Triterpenoid 2-Cyano-3,12-Dioxooleana-1,9-Dien-28-Oic Acid and Its Derivatives Inhibit Mitochondrial Lon Protease Activity: A Potential Novel Pathway for the Induction of Lymphoma Cell Death.

Steven H. Bernstein, MD, Bin Lin, PhD, Shannon Hilchey, PhD, N. Villaluna, L. Chen, K. Madura, Kim Morse, Hollie Metcalf, Michael Andreeff, MD, PhD, Paul S Brookes, PhD, Carolyn K Suzuki, PhD

Blood (2009) 114 (22): 414.

https://doi.org/10.1182/blood.V114.22.414.414

Published: 2009

Journal Articles

Experience with a Modified Nijmegen-Bethesda Method for Measurement of Inhibitors in Hemophilia Patients: The CDC Inhibitor Surveillance Pilot Project.

Connie H. Miller, PhD, S. Jean Platt, MT-ASCP, Thomas Abshire, M.D., Doreen Brettler, M.D., Paula Brockenstedt, M.D., Jorge DiPaola, M.D., Gita Massey, M.D., Anne Neff, M.D., Amy Shapiro, M.D., Michael Tarantino, M.D., Brian Wicklund, M.D., Melissa Creary, MA, J. Michael Soucie, Ph.D.

Blood (2007) 110 (11): 1156.

https://doi.org/10.1182/blood.V110.11.1156.1156

Published: 2007

Journal Articles

Inhibitors of Platelet Aggregation from Diverse Haematophagous and Predaceous Hirudinea from around the World.

Roger C. Munro, PhD, Lisa J. Wakeman, MSc, Saad Al-Ismail, MD, Andrew Beddall, MD

Blood (2006) 108 (11): 4116.

https://doi.org/10.1182/blood.V108.11.4116.4116

Published: 2006

Journal Articles

ADAMTS-13 Activity and Antigen in Commercial Von Willebrand Factor Concentrates.

Inge Scharrer, MD, Martina Böhm, PhD

Blood (2005) 106 (11): 4027.

https://doi.org/10.1182/blood.V106.11.4027.4027

Published: 2005

Journal Articles

Anti-Haemostatic Properties of Diverse Haematophagous Hirudinea from around the World Could Have New Therapeutic Potentials.

Lisa Wakeman, BSc, MSc, Roger Munro, PhD, Saad Al-Ismail, MD

Blood (2005) 106 (11): 4140.

https://doi.org/10.1182/blood.V106.11.4140.4140

Published: 2005

Journal Articles

RhoF GTPase Transcription Is Upregulated in Germinal Center B-Cells, Shows Altered Expression in Malignant B-Cells, and Interacts with the ATM Pathway.

Launce G. Gouw, MD, PhD, N. Scott Reading, PhD, David K. Crockett, MS, Philippe Szankasi, PhD, Megan S. Lim, MD, Ph.D, Kojo S.J. Elenitoba-Johnson, MD

Blood (2005) 106 (11): 285.

https://doi.org/10.1182/blood.V106.11.285.285

Published: 2005

Journal Articles

The Triterpenoids 2-cyano-3,12-dioxooleana-1,9-dien-28-oic Acid (CDDO) and Their Imidazole (CDDO-Im) and Dinitrile Derivatives (DI-CDDO) Elicit Apoptosis through a Novel Mitochondrial Pathway.

Paul Brookes, PhD, Andrew Tompkins, Kimberly Morse, Shannon Hilchey, PhD, Suhail Salim, Denise Ray, PhD, Richard Phipps, PhD, Steven H. Bernstein, MD

Blood (2005) 106 (11): 2426.

https://doi.org/10.1182/blood.V106.11.2426.2426

Published: 2005

Journal Articles

Crystal Structure of the Integrin αIIBβ3 Headpiece at 2.7–3.1 Å: Structure, Mechanisms of Activation and Ligand Binding, Inhibition by Eptifibatide, Tirofiban, and mAb 10E5, and Structure of the HPA-1 Alloantigen Epitope.

Timothy A. Springer, PhD, Junichi Takagi, PhD, Barry S. Coller, MD, Jia-Huai Wang, PhD, Tsan Xiao, PhD

Blood (2004) 104 (11): 327.

https://doi.org/10.1182/blood.V104.11.327.327

Published: 2004

Journal Articles

Murine Spherocytosis: Evidence for a Functional Interaction between Protein 4.1 and Na/H Exchange and for a “Protective” Role of the Gardos Channel Against Hemolysis.

Lucia De Franceschi, MD, Alicia Rivera, PhD, Isabel Bize, PhD, Mark Fleming, MD, PHD, Luanne L. Peters, PhD, Philippe Gascard, PhD, Narla Mohandas, PhD, Carlo Brugnara, MD

Blood (2004) 104 (11): 578.

https://doi.org/10.1182/blood.V104.11.578.578

Published: 2004

Journal Articles

The Effects of Chloride Channel Blockers on Platelet Cytoplasmic Free Calcium Concentration and Platelet Aggregation.

Songmei Yin, Xiaolin Chen, Danian Nie, Shuangfeng Xie, Liping Ma, Xiujiu Wang, Yu-Dan Wu, Yiqing Li, Jianhong Feng

Blood (2004) 104 (11): 3879.

https://doi.org/10.1182/blood.V104.11.3879.3879

Published: 2004

NARROW

Therapeutic Targeting of RUNX-NFATC2 Axis for Acute Promyelocytic Leukemia and T Cell Immunity

A Standardized Kit for a Chromogenic Modified Nijmegen-Bethesda Assay: Repeatability, Reproducibility, and Analytical Sensitivity

Synthetic Lethal Interaction between Apto-253 and Impaired BRCA1/2 Function

Difference in Fibrin Clot Structure in Haemophilia A and Haemophilia B

Mechanisms of Resistance to Apto-253

Analysis of Protease Activated Receptor 4 (PAR4) By Histidine Hydrogen Deuterium Exchange

Clinical and Preclinical Characterisation Of The Metabolites Of The BCR-ABL Tyrosine Kinase Inhibitor Nilotinib

Effective Targeting Of The P53/MDM2 Axis In Preclinical Models Of Infant MLL-Rearranged Acute Lymphoblastic Leukemia

Crystal Structure Of Tissue Factor Pathway Inhibitor (TFPI) Kunitz Domain 1 and 2 In Complex With An Inhibitory Cyclic Peptide,

The Major Phagocyte Peroxidase-Derived Oxidant HOSCN Stimulates Gene-Specific p38 MAPK- Dependent, NF-κb-Mediated Activation of Tissue Factor, VCAM-1 and ICAM-1 Expression In Endothelium.

The Triterpenoid 2-Cyano-3,12-Dioxooleana-1,9-Dien-28-Oic Acid and Its Derivatives Inhibit Mitochondrial Lon Protease Activity: A Potential Novel Pathway for the Induction of Lymphoma Cell Death.

Experience with a Modified Nijmegen-Bethesda Method for Measurement of Inhibitors in Hemophilia Patients: The CDC Inhibitor Surveillance Pilot Project.

Inhibitors of Platelet Aggregation from Diverse Haematophagous and Predaceous Hirudinea from around the World.

ADAMTS-13 Activity and Antigen in Commercial Von Willebrand Factor Concentrates.

Anti-Haemostatic Properties of Diverse Haematophagous Hirudinea from around the World Could Have New Therapeutic Potentials.

RhoF GTPase Transcription Is Upregulated in Germinal Center B-Cells, Shows Altered Expression in Malignant B-Cells, and Interacts with the ATM Pathway.

The Triterpenoids 2-cyano-3,12-dioxooleana-1,9-dien-28-oic Acid (CDDO) and Their Imidazole (CDDO-Im) and Dinitrile Derivatives (DI-CDDO) Elicit Apoptosis through a Novel Mitochondrial Pathway.

Crystal Structure of the Integrin αIIBβ3 Headpiece at 2.7–3.1 Å: Structure, Mechanisms of Activation and Ligand Binding, Inhibition by Eptifibatide, Tirofiban, and mAb 10E5, and Structure of the HPA-1 Alloantigen Epitope.

Murine Spherocytosis: Evidence for a Functional Interaction between Protein 4.1 and Na/H Exchange and for a “Protective” Role of the Gardos Channel Against Hemolysis.

The Effects of Chloride Channel Blockers on Platelet Cytoplasmic Free Calcium Concentration and Platelet Aggregation.

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American Society of Hematology

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American Society of Hematology

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