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Journal Articles

Feasibility and Outcome of Post-Induction Therapy Incorporating Dasatinib for Patients with Newly Diagnosed ABL-Class Fusion B-Lymphoblastic Leukemia (ABL-class Fusion B-ALL): Children's Oncology Group AALL1131

Wanda L. Salzer, Michael J. Burke, Meenakshi Devidas, Zhiguo (Bruce) Chen, Michael J. Borowitz, Andrew J Carroll, I-Ming L. Chen, Julie M. Gastier-Foster, Richard C. Harvey, Nyla A. Heerema, Charles G. Mullighan, Karen R. Rabin, Shalini C Reshmi, Cheryl L. Willman, Brent L. Wood, Naomi J. Winick, William L. Carroll, Elizabeth A. Raetz, Mignon L. Loh, Stephen P. Hunger
Journal: Blood
Blood (2023) 142 (Supplement 1): 961.
https://doi.org/10.1182/blood-2023-190495
Published: 2023
Journal Articles

Concurrent pembrolizumab with AVD for untreated classic Hodgkin lymphoma

Clinical Trials & Observations
Ryan C. Lynch, Chaitra S. Ujjani, Christina Poh, Edus H. Warren, Stephen D. Smith, Mazyar Shadman, Brian Till, Vikram M. Raghunathan, Stefan Alig, Ash A. Alizadeh, Avanti Gulhane, Delphine L. Chen, Yolanda Tseng, Hilary Coye, Megan Shelby, Susan Ottemiller, Sarith Keo, Kaitlin Verni, Hongyan Du, Jacquelin Vandermeer, Ashley Gaston, Heather Rasmussen, Paul Martin, Edmond Marzbani, Jenna Voutsinas, Ajay K. Gopal
Journal: Blood
Blood (2023) 141 (21): 2576–2586.
https://doi.org/10.1182/blood.2022019254
Published: 2023
Includes: Supplemental data
Journal Articles

Trial in Progress: First Report of the Phase 1/2 Study of the Safety and Efficacy of CPO107, a Bispecific Agent Targeting CD20/CD47 in CD20 Expressing Non-Hodgkin Lymphoma (NHL)

Alan P. Skarbnik, Franklin L. Chen, Luke Mountjoy, Zaw Win Myint, Patricia A. Young, Andrew R. Whiteley, Steven Novick, Jennifer Su, Qingxi Wang, Kevin Romanko, Xi-De Wang, Yejia Li, Shulin Zhong, Liping Song, Ranjana H. Advani
Journal: Blood
Blood (2022) 140 (Supplement 1): 12059–12060.
https://doi.org/10.1182/blood-2022-164746
Published: 2022
Journal Articles

A Phase 2 Study of Ruxolitinib with Chemotherapy in Children with Philadelphia Chromosome-like Acute Lymphoblastic Leukemia (AALL1521/INCB18424-269): Biologic Characteristics and Minimal Residual Disease Response of Patients with Non- CRLF2 -Rearranged JAK Pathway Alterations

Sarah K Tasian, Deborah S Hunter, I-Ming L Chen, Richard C Harvey, Andrew J. Carroll, Elizabeth Wagner, Shalini C Reshmi, Michael J Borowitz, Brent L. Wood, Jeannie Daniel, Meenakshi Devidas, Elizabeth A. Raetz, Stephen P. Hunger, Albert Assad, Mignon L. Loh
Journal: Blood
Blood (2022) 140 (Supplement 1): 6117–6118.
https://doi.org/10.1182/blood-2022-164699
Published: 2022
Journal Articles

Age, Sex and Self-Reported Race Differences in Immune Profiles of Hematologic Malignancy Patients

Megan M. Herr, Paul K. Wallace, Yali Zhang, George L. Chen, Sophia R. Balderman, Maureen Ross, Christine Ho, Jens Hillengass, Eunice S. Wang, Amanda Przespolewski, Elizabeth A. Griffiths, Pallawi Torka, Francisco J. Hernandez-Ilizaliturri, Paola Ghione, Philip L. McCarthy, Theresa E. Hahn
Journal: Blood
Blood (2021) 138 (Supplement 1): 4066.
https://doi.org/10.1182/blood-2021-150954
Published: 2021
Journal Articles

Trial in Progress: A Phase 2 Single Arm, Multicenter Trial to Evaluate the Efficacy of the BiTE ® Antibody Blinatumomab (Blincyto) and Vincristine Sulfate Liposomal Injection (Marqibo) in Adult Subjects with Relapsed/Refractory Philadelphia Negative CD19+ Acute Lymphoblastic Leukemia

David A Rizzieri, Jessica Leonard, Talha Badar, Franklin L. Chen, Bijal D. Shah, Zhiguo Li
Journal: Blood
Blood (2021) 138 (Supplement 1): 4404.
https://doi.org/10.1182/blood-2021-144548
Published: 2021
Journal Articles

Comparison of Current and Enhanced Risk Stratification of 21,199 Children, Adolescents, and Young Adults with Acute Lymphoblastic Leukemia Using Objective Risk Categorization Criteria: A Children's Oncology Group Report

Natalie Delrocco, Mignon L. Loh, Michael Borowitz, Karen R Rabin, Patrick A Zweidler-McKay, Kelly W Maloney, Leonard A. Mattano, Eric C Larsen, Anne L Angiolillo, Reuven J Schore, Michael J. Burke, Wanda L Salzer, Brent L. Wood, Andrew J Carroll, Nyla A. Heerema, Shalini C Reshmi, Julie M Gastier-Foster, Richard C Harvey, I-Ming L Chen, Kathryn G Roberts, Charles G. Mullighan, Cheryl L Willman, Naomi J Winick, William L. Carroll, Stephen P. Hunger, Elizabeth A. Raetz, Meenakshi Devidas, John Kairalla
Journal: Blood
Blood (2021) 138 (Supplement 1): 2382.
https://doi.org/10.1182/blood-2021-148593
Published: 2021
Journal Articles

Impact of Molecular Features of Diffuse Large B-Cell Lymphoma on Treatment Outcomes with Anti-CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy

Brian T. Hill, Caroline J Roth, Rachel Kositsky, Tushar Dave, Cassandra Love, Matthew McKinney, Ahmed Galal, Jadee L Neff, Agrima Mian, Ellen Kendall, Sarah L. Ondrejka, Matthew Chiaramonte, Govind Bhagat, Kenneth Ofori, Ran Reshef, Alexandra E. Kovach, Tarsheen Sethi, Emily F Mason, Shakthi Bhaskar, Olalekan O. Oluwole, Christopher Pallas, Nilanjan Ghosh, Robert Ferdman, George L. Chen, Francisco J. Hernandez-Ilizaliturri, Joanna C. Zurko, Ashley Cunningham, Nirav N. Shah, Boyu Hu, Deborah M. Stephens, Monalisa Ghosh, Neil Bailey, Krish Patel, John M. Pagel, Kavya Kannamma Kannan, Eric D. Hsi, Rakhee Vaidya, Andrew Ip, Andre H. Goy, Swetha Kambhampati, Robert S. Ohgami, Charalambos Andreadis, Elizabeth Thacker, Chrissie Rozzi, Clay Parker, Lanie Happ, Sandeep S. Dave
Journal: Blood
Blood (2021) 138 (Supplement 1): 165.
https://doi.org/10.1182/blood-2021-145764
Published: 2021
Journal Articles

Clinical Experience in the Randomized Phase 3 Sierra Trial: Anti-CD45 Iodine ( 131 I) Apamistamab [Iomab-B] Conditioning Enables Hematopoietic Cell Transplantation with Successful Engraftment and Acceptable Safety in Patients with Active, Relapsed/Refractory AML Not Responding to Targeted Therapies

Boglarka Gyurkocza, Rajneesh Nath, Stuart Seropian, Hannah Choe, Mark R. Litzow, Nebu V. Koshy, Patrick Stiff, Camille Abboud, Sr., Benjamin Tomlinson, Sunil Abhyankar, Parameswaran Hari, Zaid S. Al-Kadhimi, George L. Chen, Mitchell Sabloff, Johnnie J. Orozco, James M. Foran, Partow Kebriaei, Katarzyna Joanna Jamieson, Margarida Magalhaes Magalhaes-Silverman, Koen van Besien, Michael W. Schuster, Arjun Law, Moshe Levy, Hillard M Lazarus, Sergio A Giralt, Mark S. Berger, Jennifer A Spross, Avinash G Desai, Vijay Reddy, John M. Pagel
Journal: Blood
Blood (2021) 138 (Supplement 1): 1791.
https://doi.org/10.1182/blood-2021-148497
Published: 2021
Journal Articles

Gene Expression Analysis of CML Patients across the Age Spectrum

Minyoung Youn, Stephanie M. Smith, Alex Gia Lee, Hee-Don Chae, Elizabeth Spiteri, Jason Erdmann, Ilana Galperin, Lara C. Murphy, Michele Donato, Parveen Abidi, Henrique Bittencourt, Norman J. Lacayo, Gary Dahl, Catherine Aftandilian, Kara L. Davis, Jairo A. Matthews, Steven M. Kornblau, Min Huang, Nathan Sumarsono, Michele Redell, Cecilia H. Fu, I-Ming L Chen, Todd A. Alonzo, Elizabeth A. Eklund, Jason Gotlib, Purvesh Khatri, Alejandro Sweet-Cordero, Nobuko Hijiya, Kathleen M. Sakamoto
Journal: Blood
Blood (2021) 138 (Supplement 1): 1473.
https://doi.org/10.1182/blood-2021-148701
Published: 2021
Journal Articles

Enhanced Risk Stratification of 21,178 Children, Adolescents, and Young Adults with Acute Lymphoblastic Leukemia (ALL) Incorporating White Blood Count (WBC), Age, and Minimal Residual Disease (MRD) at Day 8 and 29 As Continuous Variables: A Children's Oncology Group (COG) Report

Mignon L. Loh, MD, Natalie DelRocco, Michael J Borowitz, MD PhD, Karen R Rabin, MDPhD, Patrick A Zweidler-McKay, MDPhD, Kelly W Maloney, MD, Leonard A. Mattano, MD, Eric C Larsen, MD, Anne L Angiolillo, MD, Reuven J Schore, MD, Michael J Burke, MD, Wanda L Salzer, MD, Brent L Wood, MD PhD, Andrew J Carroll, PhD, Nyla A Heerema, PhD, Shalini C Reshmi, PhD, Julie M Gastier-Foster, PhD, Richard C Harvey, PhD, I-Ming L Chen, DVM, MS, Cheryl L Willman, MD, Naomi J Winick, MD, William Carroll, MD, Stephen P Hunger, MD, Elizabeth A. Raetz, MD, Meenakshi Devidas, PhD, John Kairalla, Kathryn G Roberts, PhD, Charles G Mullighan, MBBS, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
https://doi.org/10.1182/blood-2020-139081
Published: 2020
Journal Articles

Outcomes of Patients with Down Syndrome and CRLF2 -Overexpressing Acute Lymphoblastic Leukemia (ALL): A Report from the Children's Oncology Group (COG)

Karen R Rabin, MDPhD, Meenakshi Devidas, PhD, Zhiguo Chen, Yunfeng Dai, PhD, Sarah K Tasian, MD, Johann K Hitzler, MD, Kathryn G Roberts, PhD, Andrew J Carroll, PhD, Nyla A Heerema, PhD, Michael J Borowitz, MD PhD, Brent L Wood, MD PhD, Charles G Mullighan, MBBS, MD, Richard C Harvey, PhD, I-Ming L Chen, Cheryl L Willman, MD, Shalini C Reshmi, PhD, Julie M Gastier-Foster, PhD, Kelly W Maloney, MD, Eric C Larsen, MD, Reuven J Schore, MD, Michael J Burke, MD, Wanda L Salzer, MD, Naomi J Winick, MD, William L. Carroll, MD, Elizabeth A. Raetz, MD, Anne Angiolillo, MD, Mignon L. Loh, MD, Stephen P Hunger, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44–45.
https://doi.org/10.1182/blood-2020-143165
Published: 2020
Journal Articles

Outcomes of Patients with CRLF2 -Overexpressing Acute Lymphoblastic Leukemia without Down Syndrome: A Report from the Children's Oncology Group

Sarah K Tasian, MD, Yunfeng Dai, PhD, Meenakshi Devidas, PhD, Kathryn G Roberts, PhD, Richard C Harvey, PhD, I-Ming L Chen, DVM, MS, Andrew J Carroll, PhD, Nyla A Heerema, PhD, Shalini C Reshmi, PhD, Julie M Gastier-Foster, PhD, Michael J Borowitz, MD PhD, Brent L Wood, MD PhD, Charles G Mullighan, MBBS, MD, Cheryl L Willman, MD, Kelly W Maloney, MD, Eric C Larsen, MD, Anne L Angiolillo, MD, Reuven J Schore, MD, Michael J Burke, MD, Wanda L Salzer, MD, Naomi J Winick, MD, William L. Carroll, MD, Stephen P Hunger, MD, Elizabeth A. Raetz, MD, Karen R Rabin, MDPhD, Mignon L. Loh, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 45–46.
https://doi.org/10.1182/blood-2020-134327
Published: 2020
Journal Articles

Comparison of the Transcriptomic Signatures in Pediatric and Adult CML

Minyoung Youn, PhD, Hee-Don Chae, PhD, Stephanie M. Smith, MD, Alex Gia Lee, PhD, Lara C. Murphy, MD, Michele Donato, PhD, Alejandro Sweet-Cordero, Parveen Abidi, PhD, Henrique Bittencourt, MD PhD, Norman J. Lacayo, MD, Gary Dahl, Catherine Aftandilian, MD, Kara L Davis, DO, Jairo A. Matthews, Steven M. Kornblau, MD, Min Huang, PhD, Nathan Sumarsono, BS, Michele Redell, MD, Cecilia H. Fu, MD, I-Ming L Chen, Todd A. Alonzo, PhD, Elizabeth A. Eklund, MD, Jason Gotlib, MD MS, Purvesh Khatri, PhD, Nobuko Hijiya, MD, Kathleen M. Sakamoto, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
https://doi.org/10.1182/blood-2020-142270
Published: 2020
Journal Articles

Personalized Targeted Radioimmunotherapy with Anti-CD45 Iodine ( 131 I) Apamistamab [Iomab-B] in Patients with Active Relapsed or Refractory Acute Myeloid Leukemia Results in Successful Donor Hematopoietic Cells Engraftment with the Timing of Engraftment Not Related to the Radiation Dose Delivered

Boglarka Gyurkocza, MD, Rajneesh Nath, MD, Hannah Choe, MD, Stuart Seropian, MD, Patrick J. Stiff, MD, Sunil Abhyankar, MD, Edward Agura, MD, Mark Litzow, MD, Benjamin K. Tomlinson, MD, George L. Chen, MD, Parameswaran Hari, MD MRCP, Johnnie Orozco, MD, Zaid S. Al-Kadhimi, MD, Camille Abboud, MD, Koen Van Besien, MD PhD, Mitchell Sabloff, MSc,MDFRCPC, Margarida Magalhaes Magalhaes-Silverman, James M. Foran, MD, Michael W. Schuster, MD, Partow Kebriaei, MD, Moshe Y. Levy, MD, Hillard M Lazarus, MD, Sergio A. Giralt, MD, Qing Liang, PhD, Mark S. Berger, MD, Vijay Reddy, MDPhD, John M. Pagel, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42–44.
https://doi.org/10.1182/blood-2020-134948
Published: 2020
Journal Articles

High Doses of Targeted Radiation with Anti-CD45 Iodine ( 131 I) Apamistamab [Iomab-B] Do Not Correlate with Incidence of Mucositis, Febrile Neutropenia or Sepsis in the Prospective, Randomized Phase 3 Sierra Trial for Patients with Relapsed or Refractory Acute Myeloid Leukemia

Boglarka Gyurkocza, MD, Rajneesh Nath, MD, Hannah Choe, MD, Stuart Seropian, MD, Patrick J. Stiff, MD, Sunil Abhyankar, MD, Edward Agura, MD, Mark Litzow, MD, Benjamin K. Tomlinson, MD, George L. Chen, MD, Parameswaran Hari, MD MRCP, Johnnie Orozco, MD, Zaid S. Al-Kadhimi, MD, Camille Abboud, MD, Koen Van Besien, MD PhD, Mitchell Sabloff, MSc,MDFRCPC, Margarida Magalhaes Magalhaes-Silverman, James M. Foran, MD, Michael W. Schuster, MD, Partow Kebriaei, MD, Moshe Levy, MD, Hillard M Lazarus, MD, Sergio A. Giralt, MD, Qing Liang, PhD, Mark S. Berger, MD, Vijay Reddy, MDPhD, John M. Pagel, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30–31.
https://doi.org/10.1182/blood-2020-134624
Published: 2020
Journal Articles

β2- Adrenergic Signaling Regulates Graft Versus Host Disease after Allogenic Transplantation While Preserving Graft Versus Leukemia Effect

Hemn Mohammadpour, PhD DVM, Joseph L. Sarow, BS, George L. Chen, MD, Cameron R. MacDonald, BS, Umesh Sharma, MD, Megan M. Herr, PhD, Theresa E. Hahn, PhD, Elizabeth A. Repasky, PhD, Philip L. McCarthy, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1915.
https://doi.org/10.1182/blood-2019-123139
Published: 2019
Journal Articles

Development and Performance of Risk Stratification Models for AML Patients Utilizing ELN-2017 Guidelines and Additional Prognostic Factors: A SWOG Report

Era L Pogosova-Agadjanyan, BS, Anna Moseley, M.S., Megan Othus, PhD, Frederick R. Appelbaum, MD, Thomas R. Chauncey, MD PhD, I-Ming L. Chen, DVM, MS, Harry P. Erba, MD PhD, John E. Godwin, MD, Isaac C. Jenkins, MS, Min Fang, MD PhD, Mike Huynh, Kenneth J Kopecky, Alan F. List, MD, Jasmine Naru, PhD, Jerald P. Radich, MD, Emily Stevens, MD PhD, Brooke E Willborg, BS, Cheryl L. Willman, MD, Brent L Wood, MD PhD, Qing Zhang, Soheil Meshinchi, MD PhD, Derek Stirewalt, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2691.
https://doi.org/10.1182/blood-2019-124529
Published: 2019
Journal Articles

Equate, a Phase 1b/2 Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of a Novel Targeted Anti-CD6 Therapy, Itolizumab, in Subjects with Newly Diagnosed Acute Graft Versus Host Disease

John Koreth, MBBS, DPhil, Saurabh Chhabra, MD, Joseph Pidala, MD, Thomas C. Shea, MD, Madan Jagasia, MBBS, MS, MMHC, Edmund K. Waller, PhDMD, Ryotaro Nakamura, MD, Marco Mielcarek, MD, George L. Chen, MD, Gabrielle Meyers, MD, Daanish Hoda, MD, Betty K. Hamilton, MD, Cherie Tracy Ng, PhD MPH, Mark Sonnemann, Susan Light, MD, Nuwan Nanayakkara, PhD, David Essayan, MD, Joel Rothman, BS, Stephen Connelly, PhD MBA, Krishna Polu, MD, Leslie Kean, MD PhD, Jerome Ritz, MD, Robert J. Soiffer, MD, Corey Cutler, MD MPH, FRCPC
Journal: Blood
Blood (2019) 134 (Supplement_1): 4516.
https://doi.org/10.1182/blood-2019-127325
Published: 2019
Journal Articles

Re-Induction and Targeted Conditioning with Anti-CD45 Iodine ( 131 I) Apamistamab [Iomab-B] Leads to High Rates of Transplantation and Successful Engraftment in Older Patients with Active, Relapsed or Refractory (rel/ref) AML after Failure of Chemotherapy and Targeted Agents: Preliminary Midpoint Results from the Prospective, Randomized Phase 3 Sierra Trial

Boglarka Gyurkocza, MD, Rajneesh Nath, MD, Patrick J. Stiff, MD, Edward Agura, MD, Mark Litzow, MD, Ben Tomlinson, MD, Hannah K. Choe, MD, Sunil Abhyankar, MD, Stuart Seropian, MD, George L. Chen, MD, Parameswaran Hari, MBBS, MD, Zaid S. Al-Kadhimi, MD, James M. Foran, MD, Johnnie Orozco, MD, Koen Van Besien, MD PhD, Mitchell Sabloff, MD, Partow Kebriaei, MD, Moshe Yair Levy, MD, Hillard M Lazarus, MD, Sergio A Giralt, MD, Mark S. Berger, MD, Vijay Reddy, MD PhD, John M. Pagel, MD PhD DSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 5642.
https://doi.org/10.1182/blood-2019-122776
Published: 2019