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Journal Articles

GO-8: Preliminary Results of a Phase I/II Dose Escalation Trial of Gene Therapy for Haemophilia a Using a Novel Human Factor VIII Variant

Amit C Nathwani, MD PhD, Edward Tuddenham, MD, Pratima Chowdary, MD, Jenny McIntosh, PhD, Doyoung Lee, PhD, Cecilia Rosales, PhD, Mark Phillips, Jun Pie, Zhou Junfang, Michael M Meagher, PhD, Ulrike Reiss, MD, Andrew M. Davidoff, MD, Chris L Morton, Anne Riddell

Blood (2018) 132 (Supplement 1): 489.

https://doi.org/10.1182/blood-2018-99-118256

Published: 2018

Journal Articles

Analysis of a Naturally Occurring PAR4 Variant By Hydrogen/Deuterium Exchange Reveals Its Structural Rearrangement upon Activation By Thrombin and the Molecular Basis for Altered Reactivity

Xu Han, BS, MS, Lukas Hofmann, PhD, Maria de la Fuente, BS, Tivadar Orban, PhD, Nathan Alexander, PhD, Krzysztof Palczewski, PhD, Marvin T Nieman, PhD

Blood (2017) 130 (Supplement 1): 453.

https://doi.org/10.1182/blood.V130.Suppl_1.453.453

Published: 2017

Journal Articles

Long-Term Expression of Von Willebrand Factor Via Piggybac -Mediated Gene Transfer

Blake A Johnson, Anil K. Chauhan, PhD, Janice M Staber, MD

Blood (2016) 128 (22): 3511.

https://doi.org/10.1182/blood.V128.22.3511.3511

Published: 2016

Journal Articles

Steroid Dependent Recalcitrant Well's Syndrome in a Patient with Chronic Lymphocytic Leukemia (CLL) Responding to Hydroxychloroquine (HCQS)

Prabhsimranjot Singh, MBBS, Makardhwaj S Shrivastava, MBBS, Audrik Perez, MD, Kenneth Grossman, MD, Daniel Benasher, MD, Alan Astrow, MD

Blood (2016) 128 (22): 5579.

https://doi.org/10.1182/blood.V128.22.5579.5579

Published: 2016

Journal Articles

Disruption of EPCR-Dependent Functions By Plasmodium Falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Can be Rescued By a Soluble EPCR Variant

Jens E.V. Petersen, Eveline A. Bouwens, PhD, Ibai Tamayo, PhD, Louis Turner, PhD, Christian Wang, PhD, Monique Stins, PhD, Thor G. Theander, PhD, José Hermida, PhD, Thomas Lavstsen, PhD, Laurent O. Mosnier, PhD

Blood (2014) 124 (21): 577.

https://doi.org/10.1182/blood.V124.21.577.577

Published: 2014

Journal Articles

Innate Immunity, Coagulation, and Thrombosis

Bernd Engelmann, MD PhD, Steffen Massberg, MD

Blood (2014) 124 (21): SCI-28.

https://doi.org/10.1182/blood.V124.21.SCI-28.SCI-28

Published: 2014

Journal Articles

Piggybac Mediated Gene Transfer To Correct Hemophilia A

Janice M Staber, MD, Molly Pollpeter, Angela Arensdorf, Patrick L Sinn, PhD, Thomas D Rutkowski, PhD, Paul B McCray, MD

Blood (2013) 122 (21): 2900.

https://doi.org/10.1182/blood.V122.21.2900.2900

Published: 2013

Journal Articles

Characterization of Molecular Interaction of Blood Coagulation Factor VIII and Its Clearance Receptor, Low-Density Lipoprotein Receptor.

James H Kurasawa, MS, Svetlana A Shestopal, Ph.D., Elena Karnaukhova, Ph.D., Evi B Struble, PhD, Timothy K Lee, PhD, Andrey G Sarafanov, Ph.D.

Blood (2012) 120 (21): 2206.

https://doi.org/10.1182/blood.V120.21.2206.2206

Published: 2012

Journal Articles

Inhibitory Effect of an Anti-Factor VIII Antibody Fragment On Factor VIII Activity in Different Functional Assays

Mikhail V Ovanesov, PhD, James H Kurasawa, MS, Naveen Jha, PhD, Svetlana A Shestopal, PhD, Timothy K Lee, PhD, Andrey G Sarafanov, Ph.D.

Blood (2012) 120 (21): 4387.

https://doi.org/10.1182/blood.V120.21.4387.4387

Published: 2012

Journal Articles

Platelet-Targeted, Thrombin-Activatable Fibrinolytic Pro-Drugs As Novel Therapies: Application to the Prothrombotic Disorder of Heparin-Induced Thrombocytopenia (HIT)

Rudy Fuentes, PhD, Hyun Sook Ahn, Vincent M. Hayes, Valerie Tutwiler, Yuhuan Wang, PhD, Daniel W. Bougie, PhD, M. Anna Kowalska, PhD, Lubica Rauova, M.D., Ph.D., Richard H. Aster, MD, Douglas B. Cines, MD, Vladimir R Muzykantov, MD PhD, Mortimer Poncz, MD, Sergei Zaitsev, PhD

Blood (2012) 120 (21): 1171.

https://doi.org/10.1182/blood.V120.21.1171.1171

Published: 2012

Journal Articles

Expression of the Light Chain of Coagulation Factor VIII in Insect Cells

Svetlana A Shestopal, PhD, James H Kurasawa, MS, Timothy K Lee, PhD, Andrey G Sarafanov, PhD

Blood (2011) 118 (21): 2269.

https://doi.org/10.1182/blood.V118.21.2269.2269

Published: 2011

Journal Articles

Nilotinib, in Comparison to Both Dasatinib and Imatinib, Possesses a Greatly Prolonged Residence Time When Bound to the BCR-ABL Kinase SH1 Domain

Paul W. Manley, Ph. D., Sandra W. Cowan-Jacob, Gabriele Fendrich, Wolfgang Jahnke, Doriano Fabbro

Blood (2011) 118 (21): 1674.

https://doi.org/10.1182/blood.V118.21.1674.1674

Published: 2011

Journal Articles

Platelet-Targeted Pro-Urokinase as a Novel Thromboprophylaxis Fibrinolytic Strategy

Rudy Fuentes, M. Anna Kowalska, PhD, Samira Tliba, Daniel W. Bougie, PhD, Richard H. Aster, MD, Douglas B. Cines, MD, Vladimir R. Muzykantov, Mortimer Poncz, MD, Sergei Zaitsev

Blood (2010) 116 (21): 3339.

https://doi.org/10.1182/blood.V116.21.3339.3339

Published: 2010

Journal Articles

A Gene Transfer Approach towards Hemophilia A Correction Using the Piggybac Transposon Vector.

Janice M. Staber, MD, Erin R Burnight, Pavel Korsakov, Joseph Kaminski, MD, Nancy L Craig, PhD, Paul B McCray, MD

Blood (2010) 116 (21): 1477.

https://doi.org/10.1182/blood.V116.21.1477.1477

Published: 2010

Journal Articles

Anopheline Orthologs of the Human Erythroid Heme Exporter, FLVCR, Export Heme: Potential Targets to Inhibit Plasmodium Transmission

Jong J Jeong, PhD, Anwar A Khan, PhD, Michael Lamm, BS, Stefan M Kanzok, PhD, John G. Quigley, MD

Blood (2010) 116 (21): 2.

https://doi.org/10.1182/blood.V116.21.2.2

Published: 2010

Journal Articles

Compound Heterozygosity of a W493C Substitution and R704/Premature Stop Codon within the γ-Glutamyl Carboxylase in Combined Vitamin K-Dependent Coagulation Factor Deficiency in a French Family.

Dhouha Darghouth, PhD, Kevin W Hallgren, Odile Issertial, Amine Bazaa, PhD, Kathleen L Berkner, PhD, Jean-Philippe Rosa, MD, PhD, Rémi Favier, MD

Blood (2009) 114 (22): 1302.

https://doi.org/10.1182/blood.V114.22.1302.1302

Published: 2009

Journal Articles

Methyl Dehydro-Jasmonate Has Anti-Inflammatory Effect Cells and Its Molecular Targets Mir-155 and NF-Kb Pathway against LPS Stimulation On RAW264.7.

Hye-Ja Lee, Hung-The Dang, Gyeoung-Jin Kang, Jee H Jung, PhD, Hee-Kyoung Kang, Hyejin Shin, MS, Josef T. Prchal, MD, Eun-Sook Yoo, PhD, Donghoon Yoon, PhD

Blood (2009) 114 (22): 1357.

https://doi.org/10.1182/blood.V114.22.1357.1357

Published: 2009

Journal Articles

Engineering VSV-IFN-NIS for the Treatment of Multiple Myeloma.

Shruthi Naik, Rebecca A. Nace, Elizabeth A. Hadac, David Dingli, M.D., PhD., Mark Federspiel, Glen N. Barber, Stephen J. Russell, MD, PhD

Blood (2009) 114 (22): 378.

https://doi.org/10.1182/blood.V114.22.378.378

Published: 2009

Journal Articles

Gene Transfer Targeting Hepatocytes Using the PiggyBac Transposon System: An Approach towards Hemophilia A Correction and Long Term Expression of Factor VIII.

Janice M. Staber, MD, Erin Burnight, Marie- Ellen Sarvida, MD, Anton McCaffrey, PhD, Joseph Kaminski, MD, Paul McCray, MD

Blood (2009) 114 (22): 3575.

https://doi.org/10.1182/blood.V114.22.3575.3575

Published: 2009

Journal Articles

Neutrophil p29 Peroxiredoxin VI/aiPLA2 (p29 Prdx VI) Enhances Superoxide Production by the NADPH Oxidase in a Manner Dependent On the PLA2 Active Site.

Michael Ellison, Gail Thurman, Daniel R. Ambruso, MD

Blood (2009) 114 (22): 3592.

https://doi.org/10.1182/blood.V114.22.3592.3592

Published: 2009

NARROW

GO-8: Preliminary Results of a Phase I/II Dose Escalation Trial of Gene Therapy for Haemophilia a Using a Novel Human Factor VIII Variant

Analysis of a Naturally Occurring PAR4 Variant By Hydrogen/Deuterium Exchange Reveals Its Structural Rearrangement upon Activation By Thrombin and the Molecular Basis for Altered Reactivity

Long-Term Expression of Von Willebrand Factor Via Piggybac -Mediated Gene Transfer

Steroid Dependent Recalcitrant Well's Syndrome in a Patient with Chronic Lymphocytic Leukemia (CLL) Responding to Hydroxychloroquine (HCQS)

Disruption of EPCR-Dependent Functions By Plasmodium Falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Can be Rescued By a Soluble EPCR Variant

Innate Immunity, Coagulation, and Thrombosis

Piggybac Mediated Gene Transfer To Correct Hemophilia A

Characterization of Molecular Interaction of Blood Coagulation Factor VIII and Its Clearance Receptor, Low-Density Lipoprotein Receptor.

Inhibitory Effect of an Anti-Factor VIII Antibody Fragment On Factor VIII Activity in Different Functional Assays

Platelet-Targeted, Thrombin-Activatable Fibrinolytic Pro-Drugs As Novel Therapies: Application to the Prothrombotic Disorder of Heparin-Induced Thrombocytopenia (HIT)

Expression of the Light Chain of Coagulation Factor VIII in Insect Cells

Nilotinib, in Comparison to Both Dasatinib and Imatinib, Possesses a Greatly Prolonged Residence Time When Bound to the BCR-ABL Kinase SH1 Domain

Platelet-Targeted Pro-Urokinase as a Novel Thromboprophylaxis Fibrinolytic Strategy

A Gene Transfer Approach towards Hemophilia A Correction Using the Piggybac Transposon Vector.

Anopheline Orthologs of the Human Erythroid Heme Exporter, FLVCR, Export Heme: Potential Targets to Inhibit Plasmodium Transmission

Compound Heterozygosity of a W493C Substitution and R704/Premature Stop Codon within the γ-Glutamyl Carboxylase in Combined Vitamin K-Dependent Coagulation Factor Deficiency in a French Family.

Methyl Dehydro-Jasmonate Has Anti-Inflammatory Effect Cells and Its Molecular Targets Mir-155 and NF-Kb Pathway against LPS Stimulation On RAW264.7.

Engineering VSV-IFN-NIS for the Treatment of Multiple Myeloma.

Gene Transfer Targeting Hepatocytes Using the PiggyBac Transposon System: An Approach towards Hemophilia A Correction and Long Term Expression of Factor VIII.

Neutrophil p29 Peroxiredoxin VI/aiPLA2 (p29 Prdx VI) Enhances Superoxide Production by the NADPH Oxidase in a Manner Dependent On the PLA2 Active Site.

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American Society of Hematology

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American Society of Hematology

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