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Journal Articles

Relative Depletion of Soluble Interleukin 6 Receptors Abolished the Development of Cytokine Release Syndrome after CART19/22 and Lenalidomide Treatment for Lymphoma

Caixia Li, Changfeng Zhang, PhD, Xiaochen Chen, Ying Zhang, Jia Chen, MD, Liqing Kang, Xiaoyan Lou, Jin Zhou, Xiangping Zong, Zhen Yang, Jiaqi Li, Wei Qi, Lei Yu, Depei Wu, MD PhD

Blood (2019) 134 (Supplement_1): 5313.

https://doi.org/10.1182/blood-2019-126821

Published: 2019

Journal Articles

Biomarker Response to Oral Eliglustat in Adults with Gaucher Disease Type 1: Results from 4 Completed Clinical Trials

Neal J Weinreb, MD, Timothy M Cox, MD, Pramod K. Mistry, MD PhD FRCP, Joel Charrow, MD, Elena Lukina, MD PhD Professor, Meredith C. Foster, ScD, M. Judith Peterschmitt, MD

Blood (2019) 134 (Supplement_1): 4859.

https://doi.org/10.1182/blood-2019-127337

Published: 2019

Journal Articles

Long-Term Effects of Oral Eliglustat on Skeletal Manifestations of Gaucher Disease Type 1: Results from Four Completed Clinical Trials

Pramod K. Mistry, MD PhD FRCP, Joel Charrow, MD, Timothy Cox, MD, Elena Lukina, MD PhD, Theodore Marinakis, MD, Meredith C. Foster, ScD, Sebastiaan J.M. Gaemers, MD, Judith Peterschmitt, MD

Blood (2018) 132 (Supplement 1): 2396.

https://doi.org/10.1182/blood-2018-99-117289

Published: 2018

Journal Articles

Osteopontin Mediates Murine Transfusion-Related Acute Lung Injury through Stimulation of Pulmonary Neutrophil Accumulation

Rick Kapur, MDPhDMSc, Gopinath Kasetty, PhD, Johan Rebetz, PhD, Arne Egesten, MD PhD, John W Semple, PhD

Blood (2018) 132 (Supplement 1): 739.

https://doi.org/10.1182/blood-2018-99-115770

Published: 2018

Journal Articles

An Exploratory Study of Cytokine Markers of Cancer-Related Cognitive Impairment in Hematological Malignancy

Samantha J Mayo, PhD RN, Rob C. Laister, PhD, Sean B Rourke, PhD, John Kuruvilla, MD

Blood (2018) 132 (Supplement 1): 5914.

https://doi.org/10.1182/blood-2018-99-118474

Published: 2018

Journal Articles

Gastrointestinal Flora Dictates the Biological Response in Murine Transfusion Related Acute Lung Injury (TRALI)

Rick Kapur, MDPhDMSc, Michael Kim, BSc, Johan Rebetz, PhD, Alisa Takabe-French, Noel Kim, Shanjeevan Shanmugabhavananthan, BSc, Edwin R. Speck, BRT, John W Semple, PhD

Blood (2017) 130 (Supplement 1): 766.

https://doi.org/10.1182/blood.V130.Suppl_1.766.766

Published: 2017

Journal Articles

Cerdulatinib Pharmacodynamics and Relationships to Tumor Response Following Oral Dosing in Patients with Relapsed/Refractory B Cell Malignancies: Results from a Phase I Dose Escalation Study

Gregory P. Coffey, PhD, Jiajia Feng, MD, Andreas Betz, PhD, Anjali Pandey, PhD, Matt Birrell, B.S., Janet M. Leeds, PhD, Kenneth Der, PhD, Sabah Kadri, PhD, Pin Lu, PhD, Jeremy Segal, PhD, Lynn Wang, MD PhD, Glenn Michelson, MD, John T Curnutte, MD PhD, Pamela B. Conley, PhD

Blood (2017) 130 (Supplement 1): 2782.

https://doi.org/10.1182/blood.V130.Suppl_1.2782.2782

Published: 2017

Journal Articles

C-Reactive Protein Promotes Bone Destruction in Human Myeloma By Stimulating Myeloma Cell Production of Osteolytic Cytokines Via the CD32/FcγRII-p38MAPK-Twist Axis

Jing Yang, PhD, Zhiqiang Liu, PhD, Huan Liu, PhD, Jin He, Jianling Yang, PhD, Pei Lin, MDDM,MDC, Qiang WANG, PhD, Juan Du, PhD MD, Wencai Ma, Richard E Davis, BSPharm, MS, Robert Z. Orlowski, MD PhD, Jian Hou, MD, Qing Yi, MD PhD

Blood (2017) 130 (Supplement 1): 3043.

https://doi.org/10.1182/blood.V130.Suppl_1.3043.3043

Published: 2017

Journal Articles

CD4+CD25+Foxp3+ T Regulatory Cells Protect Against Murine Antibody-Mediated Transfusion-Related Acute Lung Injury (TRALI)

Rick Kapur, MD PhD, Michael Kim, BSc, Shanjee Shanmugabhavananthan, Edwin R. Speck, BRT, Rukhsana Aslam, PhD, Li Guo, MD, Anne Zufferey, PhD, John W. Semple, PhD

Blood (2015) 126 (23): 2342.

https://doi.org/10.1182/blood.V126.23.2342.2342

Published: 2015

Journal Articles

C-Reactive Protein (CRP) Enhances Murine Antibody-Mediated Transfusion Related Acute Lung Injury (TRALI)

Rick Kapur, MD PhD, Michael Kim, BSc, Shanjee Shanmugabhavananthan, Edwin R. Speck, BRT, Rukhsana Aslam, PhD, Li Guo, MD, Anne Zufferey, PhD, John W. Semple, PhD

Blood (2015) 126 (23): 3561.

https://doi.org/10.1182/blood.V126.23.3561.3561

Published: 2015

Journal Articles

Assessment of Signalling Pathways in Myeloma Bone Disease Using Selected Parameters of Bone Marow Microenvironment

Jiri Minarik, MD PhD, Patrik Flodr, MD, Tomas Pika, MD PhD, Jaroslav Bacovsky, MD PhD, Pavla Latalova, MD, Petra Pusciznova, MD, Vlastimil Scudla, prof, MD PhD

Blood (2014) 124 (21): 5679.

https://doi.org/10.1182/blood.V124.21.5679.5679

Published: 2014

Journal Articles

The Use Of Selected Parameters Of Bone Microenvironment For The Assessment Of Skeletal Involvement and Activity In Multiple Myeloma and Monoclonal Gammopathy Of Undetermined Significance

Jiri Minarik, MD, PhD, Petra Pusciznova, MD, Pavla Petrova, MD, Miroslav Herman, prof. MD, Ph.D., Tomas Pika, MD, PhD, Jan Hrbek, MD, Jaroslav Bacovsky, MD, Ph.D., Jana Zapletalova, Vlastimil Scudla, Prof. MD, Ph.D.

Blood (2013) 122 (21): 5339.

https://doi.org/10.1182/blood.V122.21.5339.5339

Published: 2013

Journal Articles

Osteocytes Support Hematopoiesis by Altering the Bone Marrow Microenvironment Through Gsα Signaling

Daniela S. Krause, MD, PhD, Keertik Fulzele, PhD, Kevin Barry, Sutada Lotinun, Roland Baron, Lynda Bonewald, Jian Q Feng, Min Chen, Lee S Weinstein, Mary Bouxsein, David T. Scadden, MD, Paola Divieti-Pajevic, MD PhD

Blood (2011) 118 (21): 219.

https://doi.org/10.1182/blood.V118.21.219.219

Published: 2011

Journal Articles

Brain-Derived Neurotrophic Factor Is a Potential Osteoclast Stimulatory Factor In Multiple Myeloma

Chun-Yan Sun, Yu Hu, Xiao-Mei She, You Qin, Lu Zhang, Lei Chen, Li-Sha Ai, Jun Fang

Blood (2010) 116 (21): 1917.

https://doi.org/10.1182/blood.V116.21.1917.1917

Published: 2010

Journal Articles

CMV Specific T Cells for Adoptive Transfer Exhibit Multiple Effector Functions Associated with Protective Immunity Including the Concurrent Production of Cytokines and Cytolytic Activity

Leighton E Clancy, Kenneth P Micklethwaite, Emily Blyth, Upinder Sandher, David J Gottlieb, MD, FRACP, FRCPA

Blood (2008) 112 (11): 3481.

https://doi.org/10.1182/blood.V112.11.3481.3481

Published: 2008

Journal Articles

Macrophage Inflammatory Protein (MIP)-3α/CCL20 and Its Receptor CCR6 Are Overexpressed in the Bone Microenvironment and Involved in Osteoclast Formation in Multiple Myeloma Patients.

Nicola Giuliani, MD, PhD, Gina Lisignoli, PhD, Sara Tagliaferri, Mirca Lazzaretti, PhD, Francesca Morandi, Simona Colla, PhD, Cristina Manferdini, Beatrice Tonnarelli, Vittorio Rizzoli, MD, PhD

Blood (2007) 110 (11): 3510.

https://doi.org/10.1182/blood.V110.11.3510.3510

Published: 2007

Journal Articles

Elevated Circulating Levels of Thrombospondin-1 in Plasma Are Associated with Increased Circulating Levels of TGFb and Pro-Inflammatory Cytokines in Patients Afflicted with Rheumatoid Arthritis: Utilization of the Multiplexed Protein Profiling on Microarray by Rolling-Circle Amplification Technique.

Mario C. Rico, MD, Joanne M. Manns, Ph. D., Hien Nguyen, Nicole Beharry, Meera Reddy, MD, Audrey B. Uknis, MD, Raul A. De La Cadena, MD

Blood (2006) 108 (11): 1284.

https://doi.org/10.1182/blood.V108.11.1284.1284

Published: 2006

Journal Articles

Myeloma Cell Expression of Candidate Genes for Osteolytic Bone Disease - Over-Expression of DKK1 Correlates with Clinical Bone Involvment.

Jacob Haaber, Lene M. Knudsen, Inger M. Dahl, Niels Abildgaard, Marianne Lodahl, Thomas Rasmussen

Blood (2006) 108 (11): 3406.

https://doi.org/10.1182/blood.V108.11.3406.3406

Published: 2006

Journal Articles

Inhibition of ERK1/2 Activity by the MEK1/2 Inhibitor AZD6244 (ARRY-142886) Induces Human Multiple Myeloma Cell Apoptosis in the Bone Marrow Microenvironment: A New Therapeutic Strategy for MM.

Yu-Tzu Tai, PhD, Xian-Feng Li, M.S., Iris Breitkreutz, M.D., Weihua Song, M.D., Peter Burger, B.S., Matthew Rumizen, Teru Hideshima, M.D. Ph.D., Klaus Podar, M.D. Ph.D., Irene Ghobrial, M.D., Robert Schlossman, M.D., Paul Richardson, M.D., Nikhil C. Munshi, M.D., Kenneth C. Anderson, M.D.

Blood (2006) 108 (11): 3460.

https://doi.org/10.1182/blood.V108.11.3460.3460

Published: 2006

Journal Articles

AZD6244 (ARRY-142886), a Potent and Selective MEK1/2 Inhibitor Blocks the ERK1/2 Signaling Pathway, Inhibits Osteoclast Differentiation and Activation in Multiple Myeloma: Clinical Implications.

Iris Breitkreutz, MD, Sonia Vallet, MD, Marc S. Raab, MD, Xianfeng Li, Noopur Raje, MD, Teru Hideshima, MD, PhD, Dharminder Chauhan, PhD, Nikhil Munshi, MD, Kenneth C. Anderson, MD, Yu-Tzu Tai, PhD

Blood (2006) 108 (11): 3467.

https://doi.org/10.1182/blood.V108.11.3467.3467

Published: 2006

NARROW

Relative Depletion of Soluble Interleukin 6 Receptors Abolished the Development of Cytokine Release Syndrome after CART19/22 and Lenalidomide Treatment for Lymphoma

Biomarker Response to Oral Eliglustat in Adults with Gaucher Disease Type 1: Results from 4 Completed Clinical Trials

Long-Term Effects of Oral Eliglustat on Skeletal Manifestations of Gaucher Disease Type 1: Results from Four Completed Clinical Trials

Osteopontin Mediates Murine Transfusion-Related Acute Lung Injury through Stimulation of Pulmonary Neutrophil Accumulation

An Exploratory Study of Cytokine Markers of Cancer-Related Cognitive Impairment in Hematological Malignancy

Gastrointestinal Flora Dictates the Biological Response in Murine Transfusion Related Acute Lung Injury (TRALI)

Cerdulatinib Pharmacodynamics and Relationships to Tumor Response Following Oral Dosing in Patients with Relapsed/Refractory B Cell Malignancies: Results from a Phase I Dose Escalation Study

C-Reactive Protein Promotes Bone Destruction in Human Myeloma By Stimulating Myeloma Cell Production of Osteolytic Cytokines Via the CD32/FcγRII-p38MAPK-Twist Axis

CD4+CD25+Foxp3+ T Regulatory Cells Protect Against Murine Antibody-Mediated Transfusion-Related Acute Lung Injury (TRALI)

C-Reactive Protein (CRP) Enhances Murine Antibody-Mediated Transfusion Related Acute Lung Injury (TRALI)

Assessment of Signalling Pathways in Myeloma Bone Disease Using Selected Parameters of Bone Marow Microenvironment

The Use Of Selected Parameters Of Bone Microenvironment For The Assessment Of Skeletal Involvement and Activity In Multiple Myeloma and Monoclonal Gammopathy Of Undetermined Significance

Osteocytes Support Hematopoiesis by Altering the Bone Marrow Microenvironment Through Gsα Signaling

Brain-Derived Neurotrophic Factor Is a Potential Osteoclast Stimulatory Factor In Multiple Myeloma

CMV Specific T Cells for Adoptive Transfer Exhibit Multiple Effector Functions Associated with Protective Immunity Including the Concurrent Production of Cytokines and Cytolytic Activity

Macrophage Inflammatory Protein (MIP)-3α/CCL20 and Its Receptor CCR6 Are Overexpressed in the Bone Microenvironment and Involved in Osteoclast Formation in Multiple Myeloma Patients.

Elevated Circulating Levels of Thrombospondin-1 in Plasma Are Associated with Increased Circulating Levels of TGFb and Pro-Inflammatory Cytokines in Patients Afflicted with Rheumatoid Arthritis: Utilization of the Multiplexed Protein Profiling on Microarray by Rolling-Circle Amplification Technique.

Myeloma Cell Expression of Candidate Genes for Osteolytic Bone Disease - Over-Expression of DKK1 Correlates with Clinical Bone Involvment.

Inhibition of ERK1/2 Activity by the MEK1/2 Inhibitor AZD6244 (ARRY-142886) Induces Human Multiple Myeloma Cell Apoptosis in the Bone Marrow Microenvironment: A New Therapeutic Strategy for MM.

AZD6244 (ARRY-142886), a Potent and Selective MEK1/2 Inhibitor Blocks the ERK1/2 Signaling Pathway, Inhibits Osteoclast Differentiation and Activation in Multiple Myeloma: Clinical Implications.

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American Society of Hematology

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American Society of Hematology

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