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Journal Articles

KIFC1 Mediates Centrosome Clustering Prior to Proplatelet Formation from Megakaryocytes

Adrian R. Wilkie, PhD, Leila J. Noetzli, PhD, Genevieve Couldwell, Anthony R. Sciaudone, Anjana Ray, PhD, Kellie R. Machlus, PhD, Joseph E. Italiano, Jr., BS, PhD

Blood (2019) 134 (Supplement_1): 721.

https://doi.org/10.1182/blood-2019-130803

Published: 2019

Journal Articles

New Insights into Deregulated Gene Expression Pathways in MLL- and AF10 -Rearranged T-Lineage Acute Lymphoblastic Leukemia

Huining Kang, PhD, Nitesh Sharma, PhD, Christian K Nickl, Scott Ness, PhD, Meenakshi Devidas, PhD, Brent L. Wood, MD PhD, Barbara L. Asselin, MD, Elizabeth Raetz, MD, William L. Carroll, MD, Naomi Winick, MD, Mignon L. Loh, MD, Stephen P. Hunger, MD, Nyla A. Heerema, PhD, Andrew J. Carroll, PhD, Kimberly P. Dunsmore, MD, Richard S. Larson, MD PhD, Stuart S. Winter, MD, Ksenia Matlawska-Wasowska, PhD

Blood (2016) 128 (22): 2906.

https://doi.org/10.1182/blood.V128.22.2906.2906

Published: 2016

Journal Articles

ETS1 Expression Is Upregulated in Chronic Myeloid Leukemia (CML) and the ETS1 Transcriptional Program Correlates with Disease Progression Towards Blast Crisis

Christophe Desterke, PhD, Maud Voldoire, MD, Nathalie Sorel, Marie Laure Bonnet, Sarah Pagliaro, PharmD, Annelise Bennaceur-Griscelli, MD PhD, Emilie Cayssials, MD, Jean-Claude Chomel, PharmD PhD, Ali G Turhan, MD, PhD

Blood (2016) 128 (22): 442.

https://doi.org/10.1182/blood.V128.22.442.442

Published: 2016

Journal Articles

Filanesib Primarily Initiates the Apoptotic Program By Activating Bax through a Calpain-Dependent Mechanism

Susana Hernández-García, Lorena González-Méndez, Irena Misiewicz-Krzeminska, Esperanza Macarena Algarín, Ana Alicia López-Iglesias, Laura San-Segundo, Montserrat Martín-Sánchez, Teresa Paíno, Norma C Gutierrez, Mercedes Garayoa, Brian Tunquist, Maria-Victoria Mateos, Enrique M Ocio

Blood (2015) 126 (23): 5353.

https://doi.org/10.1182/blood.V126.23.5353.5353

Published: 2015

Journal Articles

Myosin-IIa Is Required for Leukemia Cell Extravasation and Its Inhibition Reduces Leukemia Dissemination and Prolongs Survival in a Mouse Model of Acute Lymphoblastic Leukemia

Jordan Jacobelli, PhD, Eric Wigton, Scott B Thompson

Blood (2014) 124 (21): 967.

https://doi.org/10.1182/blood.V124.21.967.967

Published: 2014

Journal Articles

ARRY-520 Combined With Pomalidomide Displays Enhanced Anti-Tumor Activity In Preclinical Models Of Multiple Myeloma

Michael J Humphries, PhD, Deborah Anderson, Lance Williams, Rob Rieger, Brian Tunquist, PhD, Duncan Walker, PhD

Blood (2013) 122 (21): 3167.

https://doi.org/10.1182/blood.V122.21.3167.3167

Published: 2013

Journal Articles

Whole Exome Sequencing Detecting Kinesin Family Gene Defects In Myeloid Neoplasm

Chantana Polprasert, MD, Hideki Makishima, MD, PhD, Bartlomiej P Przychodzen, PhD, Naoko Hosono, MD, PhD, Wenyi Shen, MD, Dayong Huang, MD, Yuichi Shiraishi, PhD, Satoru Miyano, PhD, Kenichi Yoshida, MD, Seishi Ogawa, MD, PhD, Jaroslaw P. Maciejewski, MD, PhD

Blood (2013) 122 (21): 2762.

https://doi.org/10.1182/blood.V122.21.2762.2762

Published: 2013

Journal Articles

How Does CD47-SIRPα ‘Don’t Eat Me Signal’ Physically Signal Self

Sosale Nisha, Dennis E. Discher, Ph.D.

Blood (2013) 122 (21): 953.

https://doi.org/10.1182/blood.V122.21.953.953

Published: 2013

Journal Articles

A Rationale to Enhance the Response to Antimitotic Therapy in Acute Myeloid Leukemia

Dominik Schnerch, MD, Julia Felthaus, Monika Engelhardt, Ralph Wäsch, MD

Blood (2012) 120 (21): 1332.

https://doi.org/10.1182/blood.V120.21.1332.1332

Published: 2012

Journal Articles

Targeted Gene Disruption of Kinesin-3 Family Motors Unveils a Negative Regulatory Mechanism for Mouse Erythroblast Enucleation

Toshihiko Hanada, PhD, Yunzhe Lu, PhD, Athar H Chishti, Ph.D.

Blood (2012) 120 (21): 371.

https://doi.org/10.1182/blood.V120.21.371.371

Published: 2012

Journal Articles

Non-Muscle Myosin II Mediates Microparticle Release From Endothelial Cells Activated by Antiphospholipid Antibodies,

Venkaiah Betapudi, Ph.D., Linda Hsi, PhD, Kristi L Allen, Ph.D., Belinda Willard, PhD, Keith R. McCrae, MD

Blood (2011) 118 (21): 3343.

https://doi.org/10.1182/blood.V118.21.3343.3343

Published: 2011

Journal Articles

Platelet Generation Under Shear Force Is Modulated by Site-Specific Phosphorylation of Myosin-II Heavy Chain,

Kyle R Spinler, B.S., Jae-Won Shin, B.S., Dennis E Discher, Ph.D.

Blood (2011) 118 (21): 3262.

https://doi.org/10.1182/blood.V118.21.3262.3262

Published: 2011

Journal Articles

Trafficking Kinesin Binding Protein Is Essential for Human Erythropoiesis

Seung-Jae Noh, PhD, Y.Terry Lee, Colleen Byrnes, Antoinette Rabel, Jeffery L. Miller

Blood (2011) 118 (21): 683.

https://doi.org/10.1182/blood.V118.21.683.683

Published: 2011

Journal Articles

Bortezomib- and Thalidomide-Induced Peripheral Neuropathy (PN) in Multiple Myeloma (MM): Clinical and Molecular Analysis of 474 Patients Treated with Thalidomide-Dexamethasone (TD) or Bortezomib-TD (VTD)

Blood (2011) 118 (21): 1821.

https://doi.org/10.1182/blood.V118.21.1821.1821

Published: 2011

Journal Articles

Elevated Binding of Chronic Lymphocytic Leukemia Antibody to a Subset of Apoptotic Cells with Exposed Non-Muscle Myosin Heavy Chain IIA Correlates with Poor Patient Outcome.

Charles C. Chu, Ph.D., Rosa Catera, Ph.D., Lu Zhang, M.A., Briana M. Agagnina, Sebastien Didier, M.S., Jonathan E. Kolitz, M.D., Steven L. Allen, M.D., Kanti R. Rai, M.D., Nicholas Chiorazzi, M.D.

Blood (2009) 114 (22): 799.

https://doi.org/10.1182/blood.V114.22.799.799

Published: 2009

Journal Articles

Targeting Histone Deacetylase 6 and the Aggresome Pathway in Acute Lymphoblastic Leukemia Cells.

Augustin Rodriguez-Gonzalez, PhD, James Ch’ng, Alan K. Ikeda, M.D., Tara Lin, M.D., Bita Bahrami, Ralph Mazitschek, Ph.D., James E. Bradner, M.D., Cecilia Fu, M.D., Kathleen M. Sakamoto, M.D., Ph.D.

Blood (2007) 110 (11): 1602.

https://doi.org/10.1182/blood.V110.11.1602.1602

Published: 2007

Journal Articles

Inhibition of KSP by ARRY-520 Induces Cell Cycle Block and Cell Death Via the Mitochondrial Pathway in AML Cells.

Bing Z. Carter, PhD, Duncan H. Mak, MS, Wendy D. Schober, BS, Richard Woessner, PhD, Stefan Gross, PhD, David Harris, BS, Zeev Estrov, MD, Michael Andreeff, MD, PhD

Blood (2007) 110 (11): 2782.

https://doi.org/10.1182/blood.V110.11.2782.2782

Published: 2007

Journal Articles

ARRY-429520, a Novel KSP Inhibitor with Potent Anti-Proliferative Activity in Leukemic Cell Lines.

Christine Lemieux, Walt DeWolf, Walt Voegtli, Eli Wallace, Rich Woessner, Chris Corrette, Shelley Allen, Jeremy Hans, Qian Zhao, Tom Aicher, Joe Lyssikatos, John Robinson, Kevin Koch, James Winkler, Stefan Gross

Blood (2006) 108 (11): 4401.

https://doi.org/10.1182/blood.V108.11.4401.4401

Published: 2006

Journal Articles

ARRY-429520, a KSP Inhibitor with Efficacy in Animal Models of Solid and Liquid Tumors.

Rich Woessner, PhD, Chris Corrette, Ph.D., Shelley Allen, Ph.D., Jeremy Hans, Ph.D., Qian Zhao, Ph.D., Tom Aicher, Ph.D., Joe Lyssikatos, Ph.D., John Robinson, Ph.D., Greg Poch, Ph.D., Laura Hayter, A.S., April Cox, M.S., Patrice Lee, Ph.D., James Winkler, Ph.D., Kevin Koch, Ph.D., Eli Wallace, Ph.D.

Blood (2006) 108 (11): 4388.

https://doi.org/10.1182/blood.V108.11.4388.4388

Published: 2006

Journal Articles

Genomic Instability in Multiple Myeloma: Inducible Transfectants Provide a Model To Define the Role of RHAMM and Centrosome/Mitotic Spindle Stability in Myelomagenesis.

Brian J. Taylor, PhD, Eva Baigorri, MSc, Mary Hay, PhD, Tony Reiman, MD, Andrew R. Belch, MD, Linda M. Pilarski, PhD

Blood (2006) 108 (11): 5037.

https://doi.org/10.1182/blood.V108.11.5037.5037

Published: 2006

NARROW

KIFC1 Mediates Centrosome Clustering Prior to Proplatelet Formation from Megakaryocytes

New Insights into Deregulated Gene Expression Pathways in MLL- and AF10 -Rearranged T-Lineage Acute Lymphoblastic Leukemia

ETS1 Expression Is Upregulated in Chronic Myeloid Leukemia (CML) and the ETS1 Transcriptional Program Correlates with Disease Progression Towards Blast Crisis

Filanesib Primarily Initiates the Apoptotic Program By Activating Bax through a Calpain-Dependent Mechanism

Myosin-IIa Is Required for Leukemia Cell Extravasation and Its Inhibition Reduces Leukemia Dissemination and Prolongs Survival in a Mouse Model of Acute Lymphoblastic Leukemia

ARRY-520 Combined With Pomalidomide Displays Enhanced Anti-Tumor Activity In Preclinical Models Of Multiple Myeloma

Whole Exome Sequencing Detecting Kinesin Family Gene Defects In Myeloid Neoplasm

How Does CD47-SIRPα ‘Don’t Eat Me Signal’ Physically Signal Self

A Rationale to Enhance the Response to Antimitotic Therapy in Acute Myeloid Leukemia

Targeted Gene Disruption of Kinesin-3 Family Motors Unveils a Negative Regulatory Mechanism for Mouse Erythroblast Enucleation

Non-Muscle Myosin II Mediates Microparticle Release From Endothelial Cells Activated by Antiphospholipid Antibodies,

Platelet Generation Under Shear Force Is Modulated by Site-Specific Phosphorylation of Myosin-II Heavy Chain,

Trafficking Kinesin Binding Protein Is Essential for Human Erythropoiesis

Bortezomib- and Thalidomide-Induced Peripheral Neuropathy (PN) in Multiple Myeloma (MM): Clinical and Molecular Analysis of 474 Patients Treated with Thalidomide-Dexamethasone (TD) or Bortezomib-TD (VTD)

Elevated Binding of Chronic Lymphocytic Leukemia Antibody to a Subset of Apoptotic Cells with Exposed Non-Muscle Myosin Heavy Chain IIA Correlates with Poor Patient Outcome.

Targeting Histone Deacetylase 6 and the Aggresome Pathway in Acute Lymphoblastic Leukemia Cells.

Inhibition of KSP by ARRY-520 Induces Cell Cycle Block and Cell Death Via the Mitochondrial Pathway in AML Cells.

ARRY-429520, a Novel KSP Inhibitor with Potent Anti-Proliferative Activity in Leukemic Cell Lines.

ARRY-429520, a KSP Inhibitor with Efficacy in Animal Models of Solid and Liquid Tumors.

Genomic Instability in Multiple Myeloma: Inducible Transfectants Provide a Model To Define the Role of RHAMM and Centrosome/Mitotic Spindle Stability in Myelomagenesis.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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