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Journal Articles

mTOR Signal Pathway Inhibition Promote the Cytotoxicity of Chemotherapy on SHI-1 Cells

Jing Xu, Zhenjiang Li, Jifu Zheng, Qiong Wu, Qingming Wang, Aiping Tang, Yuan Song, Yan Fei

Blood (2019) 134 (Supplement_1): 5126.

https://doi.org/10.1182/blood-2019-126714

Published: 2019

Journal Articles

PCT3, a Combination of Active Steroidal Saponins from the Paris Forrestii (Takht.) H. Li, Displays Potent Activity Against Acute Myeloid Leukemia By Suppressing the PBX1/RNF6/AKT/mTOR Signaling Pathway

Qin Lu, MD, Yunjing Zheng, MD, Yuehu Wang, PhD, Jian Pan, PhD, Xinliang Mao, MD PhD, Shaoyan Hu, MD PhD

Blood (2017) 130 (Supplement 1): 2533.

https://doi.org/10.1182/blood.V130.Suppl_1.2533.2533

Published: 2017

Journal Articles

Molecular Characterization of F8 Secreting Cell

Osman El-Maarri, PhD, Muhammad Ahmer Jamil, Behnaz Pezeshkpoor, PhD, Nicole Nüsgen, Andrea Hofmann, PhD, Per Hoffmann, PhD, Stefanie Heilmann, PhD, Markus M Nöthen, MDPhD, Holger Frohlich, PhD, Johannes Oldenburg

Blood (2015) 126 (23): 4671.

https://doi.org/10.1182/blood.V126.23.4671.4671

Published: 2015

Journal Articles

Transcriptomic Evaluation of CD34+ Marrow Cells from Myelodysplastic Syndrome (MDS) Patients

Hogune Im, PhD, Varsha Rao, PhD, Kunju Joshi Sridhar, PhD, Rui Chen, PhD, George Mias, PhD, Yan Zhang, MD, Li Xiao, MD, Michael P Snyder, PhD, Peter L. Greenberg, MD

Blood (2014) 124 (21): 1894.

https://doi.org/10.1182/blood.V124.21.1894.1894

Published: 2014

Journal Articles

The Acquirement Of Rituximab Resistance Is Associated With De-Regulation Of The PI3K/Akt/mTOR Signaling Pathway Leading To Chemotherapy Resistance In Burkitt Lymphoma Pre-Clinical Models

Sarah Frys, BSc, Andrew Skomra, Natalie M Czuczman, BSc, Cory Mavis, BSc, MSc, Delphine C.M. Rolland, PharmD, PhD, Megan Lim, MD, PhD, Aradhana Awasthi, Ph.D, Mitchell S. Cairo, MD, Myron S. Czuczman, MD, Francisco J. Hernandez-Ilizaliturri, MD, Matthew J. Barth, MD

Blood (2013) 122 (21): 5144.

https://doi.org/10.1182/blood.V122.21.5144.5144

Published: 2013

Journal Articles

Curcumin Potentiates Antitumor Activity of Imatinib Via Inhibition of the AKT/mTOR Signaling Pathway and Down-Regulation of Bcr-Abl Gene in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Yuping Gong, MD, PhD, Yong Guo, MD, PhD, Ting Niu, MD, PhD

Blood (2012) 120 (21): 3559.

https://doi.org/10.1182/blood.V120.21.3559.3559

Published: 2012

Journal Articles

Activation of the mTOR Signaling Pathway by L-Leucine in RPS14-Deficient Erythroid Cells

Bon Ham Yip, Chaitanya Vuppusetty, Andrea Pellagatti, Aristoteles Giagounidis, MD, Ulrich Germing, Abigail A Lamikanra, David J Roberts, Marta Fernandez-Mercado, Emma-Jane McDonald, Cristina Mecucci, Sally Killick, James S Wainscoat, Jacqueline Boultwood, MD

Blood (2012) 120 (21): 171.

https://doi.org/10.1182/blood.V120.21.171.171

Published: 2012

Journal Articles

Novel Treatment for Therapy-Resistant Mantle Cell Lymphoma Targeting NF-κB and mTOR Signaling Pathways in Vitro and in Vivo

Nagendra K Chaturvedi, PhD, Rajkumar Rajule, PhD, Shukla Ashima, BS, Prakash Radhakrishnan, PhD, Amarnath Natarajan, PhD, Julie M Vose, MD, MBA, Shantaram S Joshi, PhD

Blood (2012) 120 (21): 63.

https://doi.org/10.1182/blood.V120.21.63.63

Published: 2012

Journal Articles

MLN4924, An Investigational NAE Inhibitor, Suppresses AKT and mTOR Signaling Pathway Through up Regulating REDD1 in Human Myeloma Cells

Yanyan Gu, MD, PhD, Jonathan L. Kaufman, MD, Lawrence H. Boise, PhD, Sagar Lonial, MD

Blood (2011) 118 (21): 1870.

https://doi.org/10.1182/blood.V118.21.1870.1870

Published: 2011

Journal Articles

Bipterostilbene, a Novel Compound From Rhubarb, Specifically Inhibits the Proliferation of Malignant B Cells Via Inactivation of AKT/mTOR Signaling Pathway

You Hua Yu, Na Guo, Yujing Gong, Baidong Liu, Hong Liu, Haiming Chen

Blood (2011) 118 (21): 1423.

https://doi.org/10.1182/blood.V118.21.1423.1423

Published: 2011

Journal Articles

The proteomic signature of NPM/ALK reveals deregulation of multiple cellular pathways

Megan S. Lim, Mary L. Carlson, David K. Crockett, G. Chris Fillmore, David R. Abbott, Olaotan F. Elenitoba-Johnson, Sheryl R. Tripp, George Z. Rassidakis, L. Jeffrey Medeiros, Philippe Szankasi, Kojo S. J. Elenitoba-Johnson

Blood (2009) 114 (8): 1585–1595.

https://doi.org/10.1182/blood-2009-02-204735

Published: 2009

Includes: Supplemental data

Journal Articles

Oxidative Stress-Mediated Activation of AKT/mTOR Signaling Pathway Leads to Myeloproliferative Syndrome in FoxO3 Null Mice: A Role for Lnk Adaptor Protein

Safak Yalcin, Sathish Kumar Mungamuri, Dragan Marinkovic, Xin Zhang, Wei Tong, PhD, Dana Cullen, Saghi Ghaffari, MD, PhD

Blood (2008) 112 (11): 509.

https://doi.org/10.1182/blood.V112.11.509.509

Published: 2008

Journal Articles

Activation of the mTOR Signaling Pathway in Multiple Myeloma Patients and Its Prognostic Significance.

Tommasina Guglielmelli, MD, Susanna Cappia, MD, Emilia Giugliano, MD, Roberta Merlini, MD, Stefano Mussino, MD, Elena Bacillo, MD, Enrico Bracco, PhD, Maurizio Papotti, PhD, Giuseppe Saglio, PhD

Blood (2007) 110 (11): 1493.

https://doi.org/10.1182/blood.V110.11.1493.1493

Published: 2007

Journal Articles

Influence of mTOR Signalling Pathway on the MHC I Immunopeptidome.

Marie-Hélène Fortier, Etienne Caron, Danielle De Verteuil, Claude Perreault, MD, Pierre Thibault, PhD

Blood (2007) 110 (11): 3887.

https://doi.org/10.1182/blood.V110.11.3887.3887

Published: 2007

Journal Articles

Activation of mTOR Signaling Pathway Contributes to Tumoral Cell Survival in ALK-Positive Anaplastic Large Cell Lymphoma.

Francisco Vega, MD, PhD, L. Jeffrey Medeiros, MD, Coralyn Atwell, BS, Jeong Hee Cho, MD, PhD, Ling Tian, PhD, Francois-Xavier Claret, PhD, George Z. Rassidakis, MD, PhD

Blood (2005) 106 (11): 2419.

https://doi.org/10.1182/blood.V106.11.2419.2419

Published: 2005

Journal Articles

Inhibition of AKT/mTOR Signaling Pathway Induces Cell Cycle Arrest and Apoptosis in Acute Myelogenous Leukemia.

Weina Chen, MD, PhD, Ioannis Grammatikakis, BS, Jiang Li, MD, Vassiliki Leventaki, MD, L. Jeffrey Medeiros, MD, George Z. Rassidakis, MD, PhD

Blood (2005) 106 (11): 2355.

https://doi.org/10.1182/blood.V106.11.2355.2355

Published: 2005

Journal Articles

Defibrotide, an Endothelium Protecting and Stabilizing Drug, Has Anti-Angiogenic Potential In Vitro and In Vivo.

Guenther Eissner, PhD, Edward K. Geissler, PhD, Massimo Iacobelli, MD, Reinhard Andreesen, MD, Ernst Holler, MD, Gudrun E. Koehl, PhD

Blood (2005) 106 (11): 3956.

https://doi.org/10.1182/blood.V106.11.3956.3956

Published: 2005

NARROW

mTOR Signal Pathway Inhibition Promote the Cytotoxicity of Chemotherapy on SHI-1 Cells

PCT3, a Combination of Active Steroidal Saponins from the Paris Forrestii (Takht.) H. Li, Displays Potent Activity Against Acute Myeloid Leukemia By Suppressing the PBX1/RNF6/AKT/mTOR Signaling Pathway

Molecular Characterization of F8 Secreting Cell

Transcriptomic Evaluation of CD34+ Marrow Cells from Myelodysplastic Syndrome (MDS) Patients

The Acquirement Of Rituximab Resistance Is Associated With De-Regulation Of The PI3K/Akt/mTOR Signaling Pathway Leading To Chemotherapy Resistance In Burkitt Lymphoma Pre-Clinical Models

Curcumin Potentiates Antitumor Activity of Imatinib Via Inhibition of the AKT/mTOR Signaling Pathway and Down-Regulation of Bcr-Abl Gene in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Activation of the mTOR Signaling Pathway by L-Leucine in RPS14-Deficient Erythroid Cells

Novel Treatment for Therapy-Resistant Mantle Cell Lymphoma Targeting NF-κB and mTOR Signaling Pathways in Vitro and in Vivo

MLN4924, An Investigational NAE Inhibitor, Suppresses AKT and mTOR Signaling Pathway Through up Regulating REDD1 in Human Myeloma Cells

Bipterostilbene, a Novel Compound From Rhubarb, Specifically Inhibits the Proliferation of Malignant B Cells Via Inactivation of AKT/mTOR Signaling Pathway

The proteomic signature of NPM/ALK reveals deregulation of multiple cellular pathways

Oxidative Stress-Mediated Activation of AKT/mTOR Signaling Pathway Leads to Myeloproliferative Syndrome in FoxO3 Null Mice: A Role for Lnk Adaptor Protein

Activation of the mTOR Signaling Pathway in Multiple Myeloma Patients and Its Prognostic Significance.

Influence of mTOR Signalling Pathway on the MHC I Immunopeptidome.

Activation of mTOR Signaling Pathway Contributes to Tumoral Cell Survival in ALK-Positive Anaplastic Large Cell Lymphoma.

Inhibition of AKT/mTOR Signaling Pathway Induces Cell Cycle Arrest and Apoptosis in Acute Myelogenous Leukemia.

Defibrotide, an Endothelium Protecting and Stabilizing Drug, Has Anti-Angiogenic Potential In Vitro and In Vivo.

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American Society of Hematology

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American Society of Hematology

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