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Journal Articles

Identification of Thrombospondin-1 As a Novel Substrate of Cereblon Responsible for IMiDs-Induced Venous Thromboembolism

Kiwamu Hatakeyama, MD, Yoshikane Kikushige, MD PhD, Toshihiro Miyamoto, MD PhD, Koichi Akashi, MD PhD

Blood (2019) 134 (Supplement_1): 631.

https://doi.org/10.1182/blood-2019-125670

Published: 2019

Journal Articles

Regulation of Erythroid Heme Synthesis By the Mitochondrial Clpx Unfoldase

Catherine Rondelli, Aiden Danoff, Hector Bergonia, Samantha Gillis, Julia Free, John D. Phillips, PhD, Yvette Y Yien, PhD

Blood (2019) 134 (Supplement_1): 427.

https://doi.org/10.1182/blood-2019-132039

Published: 2019

Journal Articles

In Vivo hemostatic Significance of Activated Protein C in Factor VIIIa Regulation

Amelia R. Wilhelm, B.S., Nicole A. Parsons, B.S., Charles T. Esmon, PhD, Rodney M. Camire, PhD, Lindsey A. George, MD

Blood (2019) 134 (Supplement_1): 93.

https://doi.org/10.1182/blood-2019-124493

Published: 2019

Journal Articles

Expression Levels of the TERT Gene Can be Used to Risk Stratify Aplastic Anemia Patients: Study in an Indian Cohort

Arati Khanna-Gupta, PhD, Durga Sarvepalli, Snigdha Majumder, Coral Karunakaran, Malini Manoharan, Shilpa Sudesh, Varun Bafna, Chirantan Bose, Ravi Gupta, K.S. Natraj, Sharat Damodar, MBBS, MD DM, Arkasubhra Ghosh, PhD

Blood (2017) 130 (Supplement 1): 4963.

https://doi.org/10.1182/blood.V130.Suppl_1.4963.4963

Published: 2017

Journal Articles

Mutations in the Telomerase Complex and Expression Levels of the TERT Gene Determine Severity and Outcome of Disease in Aplastic Anemia Patients

Arati Khanna-Gupta, MSc, PhD, Durga Sarvepalli, PhD, Snigdha Majumder, M.Tech, Coral Karunakaran, PhD, Malini Manoharan, PhD, Shilpa Prabhu, MBBS, MD, Varun Bafna, III, MBBS,DNB, Sakthivel Murugan SM, PhD, Chirantan Bose, MD(Path), Ravi Gupta, PhD, Nataraj KS, MD DM, Sharat Damodar, MD DM, Arkasubhra Ghosh, PhD

Blood (2016) 128 (22): 1502.

https://doi.org/10.1182/blood.V128.22.1502.1502

Published: 2016

Journal Articles

Phase I Dose-Escalation Study of Cpi-613, in Combination with Bendamustine, in Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma

Zanetta S. Lamar, MD, Scott Isom, MS, Rakhee Vaidya, MD, Anne W Beaven, MD, Zachariah A. McIver, DO

Blood (2016) 128 (22): 4163.

https://doi.org/10.1182/blood.V128.22.4163.4163

Published: 2016

Journal Articles

The Affinity of Factor X for the Intrinsic Xase Is Determined By Exosite Interactions Between the Substrate and the Enzyme Complex

Manjunath Goolyam Basavaraj, PhD, Sriram Krishnaswamy, PhD

Blood (2015) 126 (23): 1065.

https://doi.org/10.1182/blood.V126.23.1065.1065

Published: 2015

Journal Articles

New Allosteric Inhibitors of Mutant IDH1 in Acute Myeloid Leukemia

Blood (2015) 126 (23): 787.

https://doi.org/10.1182/blood.V126.23.787.787

Published: 2015

Journal Articles

Telomere Length Recovery Strongly Predicts Overall Survival in Acute Promyelocytic Leukemia

Muhamed Baljevic, MD, Bogdan Dumitriu, MD, Ju-Whei Lee, PhD, Elisabeth Paietta, PhD, Janis Racevskis, Christina Chen, BS, Eytan M. Stein, Robert E Gallagher, MD, Jacob M. Rowe, MD, Frederick R. Appelbaum, MD, Bayard L. Powell, MD, Richard A. Larson, Neal S. Young, MD, Martin S. Tallman, MD

Blood (2014) 124 (21): 2375.

https://doi.org/10.1182/blood.V124.21.2375.2375

Published: 2014

Journal Articles

Reduced Polyethylene Glycol-Conjugated B-Domain–Deleted Factor VIII (PEG-BDD-FVIII) Clearance: Selective Peg Steric Modulation without Affecting Potency

Eric Blasko, Lilley Leong, PhD MS, Derek S Sim, PhD, Liang Tang, PhD, Elena Ho, Jim Wu, Katalin Zsofia Kauser, PhD MD DSc, Babu Subramanyam

Blood (2014) 124 (21): 1471.

https://doi.org/10.1182/blood.V124.21.1471.1471

Published: 2014

Journal Articles

Lenalidomide Promotes CRBN-Mediated Ubiquitination and Degradation of IKZF1 and IKZF3

Jan Krönke, Namrata Udeshi, Anupama Narla, Peter Grauman, Slater Hurst, Marie McConkey, Tanya Svinkina, Dirk Heckl, Eamon Comer, Xiaoyu Li, Christie Ciarlo, Emily Hartman, Monica Schenone, Stuart Schreiber, Steven A. Carr, Benjamin L. Ebert

Blood (2013) 122 (21): LBA-5.

https://doi.org/10.1182/blood.V122.21.LBA-5.LBA-5

Published: 2013

Journal Articles

Targeting The Mitochondrial ClpP As a Novel Therapeutic Strategy For Acute Myeloid Leukemia

Alicia Cole, PhD, Zezhou Wang, PhD, Rachel Mattson, Etienne Coyaud, PhD, Rose Hurren, Marcela Gronda, MSc, Fengshu Lin, PhD, Neil Maclean, BSc, Elisa Leung, BSc, Yihua Qiu, MD, Nianxiang Zhang, PhD, Kevin R. Coombes, PhD, Mark D. Minden, MD PhD, Walid A. Houry, PhD, Zenyaho Hao, PhD, Steven M. Kornblau, MD, Brian Raught, PhD, Aaron Schimmer, PhD, MD

Blood (2013) 122 (21): 3937.

https://doi.org/10.1182/blood.V122.21.3937.3937

Published: 2013

Journal Articles

Constitutional Telomerase-Associated Gene Variants In Pediatric Acute Myeloid Leukemia (AML) and In Association With Chemotherapy-Related Toxicities

M. Monica Gramatges, MD, Ghadir S. Sasa, MD, Robert B. Gerbing, MA, Eunji Jo, MS, Todd A. Alonzo, PhD, Charlotte H Ahern, PhD, Soheil Meshinchi, MD, PhD, Alison A. Bertuch, MD, PhD

Blood (2013) 122 (21): 1310.

https://doi.org/10.1182/blood.V122.21.1310.1310

Published: 2013

Journal Articles

The Effect Of Physiological Metal Ions On The Procoagulant Enzyme-Cofactor Complexes Of The Extrinsic Pathway Of Coagulation

Maria Cristina Bravo, Ph.D., Catherine G McGuinness, Matthew Gissel, M.S., Thomas Orfeo, Ph.D., Kenneth G. Mann, Ph.D.

Blood (2013) 122 (21): 1096.

https://doi.org/10.1182/blood.V122.21.1096.1096

Published: 2013

Journal Articles

Constitutional Telomerase-Associated Gene Variants in Pediatric Acute Myeloid Leukemia (AML)

M. Monica Gramatges, MD, Ghadir S. Sasa, MD, Xiaodong Qi, Julian J-L Chen, PhD, Sharon E Plon, MD, PhD, Alison A. Bertuch, MD, PhD

Blood (2012) 120 (21): 1408.

https://doi.org/10.1182/blood.V120.21.1408.1408

Published: 2012

Journal Articles

Mechanisms of Sensitivity and Resistance to Histone Deacetylase Inhibitors in Diffuse Large B-Cell Lymphoma

Ana A Tula-Sanchez, Graduate, Aaron Havas, Peter Alonge, Undergraduate student, Mary E Klein, Undergraduate, Taralyn Y Rogers, Emily Szeto, Lisa M. Rimsza, MD, Catharine L Smith

Blood (2012) 120 (21): 1359.

https://doi.org/10.1182/blood.V120.21.1359.1359

Published: 2012

Journal Articles

Constitutional Telomerase-Associated Gene Variants Associated with Chemotherapy-Related Toxicities in Pediatric Acute Myeloid Leukemia (AML)

M. Monica Gramatges, MD, Todd A. Alonzo, PhD, Robert B. Gerbing, M.A., Alison A. Bertuch, MD, PhD, Soheil Meshinchi, MD, PhD

Blood (2012) 120 (21): 1403.

https://doi.org/10.1182/blood.V120.21.1403.1403

Published: 2012

Journal Articles

Conformational Dynamics of Prothrombin Dictate Its Ordered Cleavage by Prothrombinase

Michelle Homsher, PhD, Erin Zekas, BS, Sriram Krishnaswamy, Ph.D.

Blood (2012) 120 (21): 3359.

https://doi.org/10.1182/blood.V120.21.3359.3359

Published: 2012

Journal Articles

Inhibition of Platelet-Prothrombianse by a Covalent Antithrombin-Heparin Complex.

Ivan Stevic, MSc, PhD candidate, Howard H.W. Chan, MBChB, FRCPC, MSc, Ankush Chander, MBBS, MSc candidate, Leslie R. Berry, Hons. BSc., Anthony K.C. Chan, MBBS, FRCPC, FRCPath

Blood (2012) 120 (21): 2212.

https://doi.org/10.1182/blood.V120.21.2212.2212

Published: 2012

Journal Articles

Targeting the Mammalian Mitochondrial Clpp (mClpP) As a Novel Therapeutic Strategy for Acute Myeloid Leukemia

Alicia Cole, PhD, Zezhou Wang, PhD, Rachel Mattson, Rose Hurren, BSc, Fengshu Lin, PhD, Marcela Gronda, MSc, Neil Maclean, BSc, Methvin Isaac, PhD, Elisa Leung, BSc., Mohan Babu, PhD, Mahadeo A. Sukhai, PhD, Walid A. Houry, PhD, Aaron D. Schimmer, MD

Blood (2012) 120 (21): 3603.

https://doi.org/10.1182/blood.V120.21.3603.3603

Published: 2012

NARROW

Identification of Thrombospondin-1 As a Novel Substrate of Cereblon Responsible for IMiDs-Induced Venous Thromboembolism

Regulation of Erythroid Heme Synthesis By the Mitochondrial Clpx Unfoldase

In Vivo hemostatic Significance of Activated Protein C in Factor VIIIa Regulation

Expression Levels of the TERT Gene Can be Used to Risk Stratify Aplastic Anemia Patients: Study in an Indian Cohort

Mutations in the Telomerase Complex and Expression Levels of the TERT Gene Determine Severity and Outcome of Disease in Aplastic Anemia Patients

Phase I Dose-Escalation Study of Cpi-613, in Combination with Bendamustine, in Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma

The Affinity of Factor X for the Intrinsic Xase Is Determined By Exosite Interactions Between the Substrate and the Enzyme Complex

New Allosteric Inhibitors of Mutant IDH1 in Acute Myeloid Leukemia

Telomere Length Recovery Strongly Predicts Overall Survival in Acute Promyelocytic Leukemia

Reduced Polyethylene Glycol-Conjugated B-Domain–Deleted Factor VIII (PEG-BDD-FVIII) Clearance: Selective Peg Steric Modulation without Affecting Potency

Lenalidomide Promotes CRBN-Mediated Ubiquitination and Degradation of IKZF1 and IKZF3

Targeting The Mitochondrial ClpP As a Novel Therapeutic Strategy For Acute Myeloid Leukemia

Constitutional Telomerase-Associated Gene Variants In Pediatric Acute Myeloid Leukemia (AML) and In Association With Chemotherapy-Related Toxicities

The Effect Of Physiological Metal Ions On The Procoagulant Enzyme-Cofactor Complexes Of The Extrinsic Pathway Of Coagulation

Constitutional Telomerase-Associated Gene Variants in Pediatric Acute Myeloid Leukemia (AML)

Mechanisms of Sensitivity and Resistance to Histone Deacetylase Inhibitors in Diffuse Large B-Cell Lymphoma

Constitutional Telomerase-Associated Gene Variants Associated with Chemotherapy-Related Toxicities in Pediatric Acute Myeloid Leukemia (AML)

Conformational Dynamics of Prothrombin Dictate Its Ordered Cleavage by Prothrombinase

Inhibition of Platelet-Prothrombianse by a Covalent Antithrombin-Heparin Complex.

Targeting the Mammalian Mitochondrial Clpp (mClpP) As a Novel Therapeutic Strategy for Acute Myeloid Leukemia

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American Society of Hematology

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American Society of Hematology

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