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Journal Articles

Inherited Disorders of the Ras-MAPK Pathway

Christian P. Kratz, MD, Martin Zenker, MD

Blood (2018) 132 (Supplement 1): SCI-41.

https://doi.org/10.1182/blood-2018-99-109379

Published: 2018

Journal Articles

Evidence of Long Latency Periods Prior to Development of Mantle Cell Lymphoma

Frederick Racke, MD, PhD, Sabrina Simpson, M.D., Beth Christian, MD, Kristie A. Blum, MD, Robert Hasserjian, MD, Weiqiang Zhao

Blood (2010) 116 (21): 323.

https://doi.org/10.1182/blood.V116.21.323.323

Published: 2010

Journal Articles

Mast cells and the neurofibroma microenvironment

Karl Staser, Feng-Chun Yang, D. Wade Clapp

Blood (2010) 116 (2): 157–164.

https://doi.org/10.1182/blood-2009-09-242875

Published: 2010

Journal Articles

Mast Cells and Tumor Progression.

D. Wade Clapp, MD, Fengchun Yang, MD, PhD, David A. Ingram, Jr., MD, Kent A. Robertson, MD, PhD, Gary D. Hutchins, PhD, Luis F. Parada, PhD

Blood (2009) 114 (22): SCI-33.

https://doi.org/10.1182/blood.V114.22.SCI-33.SCI-33

Published: 2009

Journal Articles

Deletion of the Tumor Suppressor Gene NF1 Is An Alternative Mechanism for Aberrant Activation of the RAS Pathway and Is Found in 11% of Acute Myeloid Leukemia.

Claudia Haferlach, MD, Alexander Kohlmann, PhD, Sonja Schindela, Wolfgang Kern, Susanne Schnittger, PhD, Torsten Haferlach, MD

Blood (2009) 114 (22): 401.

https://doi.org/10.1182/blood.V114.22.401.401

Published: 2009

Journal Articles

Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1 +/− mast cells

Andrew S. McDaniel, Jayme D. Allen, Su-Jung Park, Zahara M Jaffer, Elizabeth G. Michels, Sarah J. Burgin, Shi Chen, Waylan K. Bessler, Clemens Hofmann, David A. Ingram, Jonathan Chernoff, D. Wade Clapp

Blood (2008) 112 (12): 4646–4654.

https://doi.org/10.1182/blood-2008-04-155085

Published: 2008

Journal Articles

Imatinib Mesylate Reduces Plexiform Neurofibromas by Targeting the Hematopoietic Microenvironment.

Feng-Chun Yang, MD, PhD, David Ingram, M.D., Shi Chen, M.D., Ph.D., Kent Robertson, M.D., Ph.D., Xiohong Li, Jin Yuan, Scott Knoll, Whitney Horn, Gary Hutchins, M.D., Ph.D., L. Parada, Ph.D., David Wade Clapp, M.D.

Blood (2007) 110 (11): 1915.

https://doi.org/10.1182/blood.V110.11.1915.1915

Published: 2007

Journal Articles

Loss of Pak1 Corrects Multiple Gain of Function Phenotypes in Nf1+/ − Mast Cells.

Andrew McDaniel, D. Wade Clapp, M.D., J. Chernoff

Blood (2007) 110 (11): 236.

https://doi.org/10.1182/blood.V110.11.236.236

Published: 2007

Journal Articles

Mast Cells Are Integral Components of the Tumor Microenvironment That Are Required for Plexiform Neurofibroma Progression.

Fengchun Yang, MD, PhD, David A. Ingram, MD, Shi Chen, MD, Jin Yuan, Xiaohong Li, Whitney Horn, Luis Parada, PhD, D. Wade Clapp, MD

Blood (2006) 108 (11): 677.

https://doi.org/10.1182/blood.V108.11.677.677

Published: 2006

Journal Articles

Function of the NF1 Tumor Suppressor Gene in Angiogenesis.

Amy M. Munchhof, Fang Li, Laura Mead, Hilary White, Amy Fenoglio, Feng-Chun Yang, MD, David A. Ingram, MD

Blood (2005) 106 (11): 3680.

https://doi.org/10.1182/blood.V106.11.3680.3680

Published: 2005

Journal Articles

p21-Activated Kinase 1 Regulates Hyperproliferation of Nf1 Haploinsufficient Mast Cells In Vitro and In Vivo Via Activation of the MAPK Pathway.

Andrew S. McDaniel

Blood (2005) 106 (11): 3063.

https://doi.org/10.1182/blood.V106.11.3063.3063

Published: 2005

Journal Articles

Adoptive Transfer of Nf1 +/− Bone Marrow Is Sufficient for Neurofibroma Progression in Krox20;Nf1 flox/flox Mice.

Fengchun Yang, MD, PhD

Blood (2005) 106 (11): 3064.

https://doi.org/10.1182/blood.V106.11.3064.3064

Published: 2005

Journal Articles

The Role of Neurofibromin as a GTPase Activating Protein for K-ras in Mast Cells.

Waleed F. Khalaf, Douglas A. Hardesty, Shi Chen, Feng-Chun Yang, M.D., Hilary White, Mary Jo Wenning, David A. Ingram, M.D., D. Wade Clapp, M.D.

Blood (2004) 104 (11): 2560.

https://doi.org/10.1182/blood.V104.11.2560.2560

Published: 2004

Journal Articles

Murine and Human NF1 Haploinsufficient Mast Cells Promote Alterations in Fibroblast Function and Organization of the Extracellular Matrix in Three-Dimensional Collagen Lattices and this Gain in Function Is Abrogated by the Addition of STI-571.

Fengchun Yang, M.D., Clegg Travis, Shi Chen, Xiaohong Li, Selina A. Estwick, Jin Yuan, David A. Ingram, M.D., D. Wade Clapp, M.D.

Blood (2004) 104 (11): 1465.

https://doi.org/10.1182/blood.V104.11.1465.1465

Published: 2004

NARROW

Inherited Disorders of the Ras-MAPK Pathway

Evidence of Long Latency Periods Prior to Development of Mantle Cell Lymphoma

Mast cells and the neurofibroma microenvironment

Mast Cells and Tumor Progression.

Deletion of the Tumor Suppressor Gene NF1 Is An Alternative Mechanism for Aberrant Activation of the RAS Pathway and Is Found in 11% of Acute Myeloid Leukemia.

Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1 +/− mast cells

Imatinib Mesylate Reduces Plexiform Neurofibromas by Targeting the Hematopoietic Microenvironment.

Loss of Pak1 Corrects Multiple Gain of Function Phenotypes in Nf1+/ − Mast Cells.

Mast Cells Are Integral Components of the Tumor Microenvironment That Are Required for Plexiform Neurofibroma Progression.

Function of the NF1 Tumor Suppressor Gene in Angiogenesis.

p21-Activated Kinase 1 Regulates Hyperproliferation of Nf1 Haploinsufficient Mast Cells In Vitro and In Vivo Via Activation of the MAPK Pathway.

Adoptive Transfer of Nf1 +/− Bone Marrow Is Sufficient for Neurofibroma Progression in Krox20;Nf1 flox/flox Mice.

The Role of Neurofibromin as a GTPase Activating Protein for K-ras in Mast Cells.

Murine and Human NF1 Haploinsufficient Mast Cells Promote Alterations in Fibroblast Function and Organization of the Extracellular Matrix in Three-Dimensional Collagen Lattices and this Gain in Function Is Abrogated by the Addition of STI-571.

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American Society of Hematology

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American Society of Hematology

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